Hepatobiliary surgery and nutrition最新文献

{"title":"An enigmatic abdominal mass presenting 1 year after childbirth.","authors":"Antonio Cubisino, Jules Grégory, Aurélie Beaufrère","doi":"10.21037/hbsn-2025-156","DOIUrl":"10.21037/hbsn-2025-156","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"531-533"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emphasis on waiting list management towards better prognosis of all potential liver transplant recipients.","authors":"Yongfa Huang","doi":"10.21037/hbsn-2025-310","DOIUrl":"10.21037/hbsn-2025-310","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"500-501"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic effect of surgical margin in patients undergoing hepatectomy for colorectal liver metastasis.","authors":"Katsunori Sakamoto, Yoichiro Uchida, Kentaro Kadono, Hidenobu Kojima, Asahi Sato, Takashi Ito, Takamichi Ishii, Etsuro Hatano","doi":"10.21037/hbsn-2025-192","DOIUrl":"10.21037/hbsn-2025-192","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"476-481"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking portal hypertension in hepatocellular carcinoma resection: a gradient of risk beyond black and white.","authors":"David Pereyra, Patrick Starlinger","doi":"10.21037/hbsn-2025-213","DOIUrl":"10.21037/hbsn-2025-213","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"490-493"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When technology fails: the pivotal role of meticulous clinical reasoning in unmasking an invisible colon cancer mimicking chronic ischemic colitis.","authors":"Lisha Jing, Hemiao Xu, Shuai Li, Jingjuan Liu, Jia Xu, Yabing Wang, Qingyang Zhou, Zheng Wang, Kun He","doi":"10.21037/hbsn-2025-152","DOIUrl":"10.21037/hbsn-2025-152","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"515-518"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ectopic hepatocellular carcinoma in the gallbladder.","authors":"Da-Long Wan, Chen-Guang Hua, Xu Yang, Chen Hu, Qing-Hong Ke, Yan Shen","doi":"10.21037/hbsn-2025-105","DOIUrl":"10.21037/hbsn-2025-105","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"522-525"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating liver resection outcomes post Y90 TARE with personalized dosimetry in intermediate or advanced hepatocellular carcinoma: a focus on surgical and biliary complications.","authors":"Mohamad Azhar Meerun, Carole Allimant, Valentina Schembri, Margaux Hermida, Christine Latry-Kuhn, Denis Mariano-Goulart, Fabrizio Panaro, Boris Guiu","doi":"10.21037/hbsn-24-151","DOIUrl":"10.21037/hbsn-24-151","url":null,"abstract":"<p><strong>Background: </strong>While preliminary reports on resection following downstaging using transarterial radioembolization (TARE) for intermediate or advanced hepatocellular carcinomas (HCCs) reported promising oncological outcomes, there's a notable gap in the literature concerning post operative morbidity. Contrary to post hepatectomy liver failure (PHLF), damages to the bile ducts and their potential consequences have been poorly evaluated. Thus, our aim was to explore postoperative complications in HCC patients undergoing liver resection after Y90 TARE, focusing particularly on biliary complications.</p><p><strong>Methods: </strong>Conducted from June 2015 to December 2022, this retrospective study involved 30 HCC patients undergoing liver resection post-TARE. Comprehensive data on surgical procedures, complications, and follow-up were collected. Logistic regression analyses were conducted, starting with univariate analysis followed by multivariate analysis, focusing on variables with a significance level below P<0.2.</p><p><strong>Results: </strong>The objective response rate (ORR) in the TARE-treated area was 97% at 3 months. Survival outcomes showed a median overall survival (OS) of 5.1 years and progression-free survival (PFS) of 3.5 years post-liver resection. The study found a 40% (12 out of 30 patients) rate of severe postoperative complications and a 7% (2 out of 30 patients) 90-day mortality rate. After liver resection, grade B bile leaks occurred in 20% (6 out of 30) of patients, with a third experiencing recurrence. Biliary-specific mortality was 9%. After multivariate analysis, only the interval between TARE and surgery emerged a significant risk factor for biliary complications, showing increased odds of bile leaks if surgery occurred 3-6 months post-TARE compared to after 6 months.</p><p><strong>Conclusions: </strong>This study highlights the importance of timing between TARE and surgery, suggesting a waiting period of at least 6 months. Such timing not only enhances the radiation effects of TARE but also optimizes both future liver remnant growth and patient selection.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"398-410"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding the horizons of cytoreductive surgery-hyperthermic intraperitoneal chemotherapy and liver resection for colorectal peritoneal and liver metastases.","authors":"Yoshimasa Gohda, Norihiro Kokudo","doi":"10.21037/hbsn-2025-189","DOIUrl":"10.21037/hbsn-2025-189","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"473-475"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Splenic hypertrophy predicts liver-specific complications in patients undergoing major liver resection for colorectal liver metastases, after preoperative chemotherapy.","authors":"Gerrit Josephs, Lea Hitpass, Daniel Truhn, Franziska Meister, Marie-Luise Berres, Tom Luedde, Danny Jonigk, Steven W M Olde Damink, Sven Arke Lang, Florian Vondran, Iakovos Amygdalos","doi":"10.21037/hbsn-24-121","DOIUrl":"10.21037/hbsn-24-121","url":null,"abstract":"<p><strong>Background: </strong>In patients with colorectal liver metastases (CRLM), preoperative chemotherapy may increase resectability and survival outcomes. However, cytotoxic agents can also cause chemotherapy-associated liver injury (CALI), leading to increased rates of postoperative complications. This study evaluates the association between splenic hypertrophy (SH) after preoperative chemotherapy and postoperative liver-specific complications (LSC), in patients undergoing major liver resection for CRLM.</p><p><strong>Methods: </strong>This retrospective study included patients who underwent major curative liver resection of CRLM following preoperative chemotherapy at the University Hospital RWTH Aachen (UH-RWTH) between 2010-2021. Patients with missing radiological images, incomplete data on chemotherapy regimens, or prior splenectomy were excluded. Volumetric measurements of the spleen were performed on preoperative computerized tomography (CT) and magnetic resonance imaging (MRI) images, using segmentation software (3D-Slicer). Receiver-operating characteristic (ROC) analysis was performed to determine the optimal SH cut-off for predicting postoperative LSC. Independent risk factors of postoperative LSC were examined using logistic regression.</p><p><strong>Results: </strong>A total of 115 patients were included in the study, of which 78 (68%) received oxaliplatin as part of their preoperative chemotherapy regimen. A threshold of 8.6% SH (Youden Index =0.25) was identified as predictive of postoperative LSC. Patients with SH >8.6% (n=62) received oxaliplatin significantly more often (84% <i>vs.</i> 49%; P<0.001) and exhibited higher rates of liver fibrosis (72% <i>vs.</i> 52%, P=0.03) and LSC (63% <i>vs.</i> 38%, P=0.007). Multivariable logistic regression analysis identified SH >8.6% as an independent risk factor for LSC (odds ratio 2.86, 95% confidence interval: 1.104-7.402, P=0.03).</p><p><strong>Conclusions: </strong>Preoperative SH may be a valuable predictor of postoperative LSC in patients undergoing major liver resection for CRLM, following chemotherapy. Further studies are necessary to investigate the impact on a larger cohort and find preventive strategies to mitigate and treat CALI.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"411-422"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgery-related factors for pancreatic fistula after pancreatectomy: an umbrella review.","authors":"Yu Teng, Yaoqun Wang, Sishu Yang, Guilin Nie, Ningyuan Wen, Yingyi Zhang, Nansheng Cheng, Xianze Xiong, Jiong Lu, Geng Liu, Bei Li","doi":"10.21037/hbsn-23-601","DOIUrl":"10.21037/hbsn-23-601","url":null,"abstract":"<p><strong>Background: </strong>Multiple risk or protective factors for postoperative pancreatic fistula (POPF) have been suggested in the literature of surgical specialities. We aimed to map existing evidence regarding the risk factors for POPF to help guide future clinical treatment.</p><p><strong>Methods: </strong>We performed an umbrella review by searching the Web of Science, PubMed, Embase, and Cochrane databases until June 19, 2023. Meta-analyses (MAs) that included ≥2 studies were included. Methodological quality was assessed using AMSTAR2 scores and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) tools were used to quantify the strength of the evidence.</p><p><strong>Results: </strong>Of the 42 MAs, 1 was rated as having high methodological quality, and 4 were rated as moderate. Among the 82 outcomes, 6 were supported by high-quality evidence. Moderate-quality evidence was found for 13 outcomes. The remaining outcomes had either low- or very low-quality evidence. In pancreaticoduodenectomy (PD), protective factors for all-grade POPF include pancreaticogastrostomy (PG) [<i>vs.</i> pancreaticojejunostomy (PJ), moderate quality], external pancreatic ductal stent (<i>vs.</i> no stents, high quality). Risk factors for all-grade POPF in PD include pancreatic duct occlusion (<i>vs.</i> no occlusion, moderate quality) and sealant (<i>vs.</i> no sealant, moderate quality). Polyglycolic acid mesh [<i>vs.</i> no mesh, moderate quality] was a protective factor for clinically relevant POPF (CR-POPF) in PD, omental/falciform ligament wrapping (<i>vs.</i> no wrapping, low quality), and artery-first PD (<i>vs.</i> standard, low quality). In distal pancreatectomy (DP), no factors for all-grade POPF were rated as high- or moderate-quality evidence. Polyglycolic acid mesh (<i>vs.</i> no mesh, moderate quality) was a protective factor for CR-POPF in DP. No factors were rated as high- or moderate-quality evidence in other types of pancreatectomy. In addition, high- and moderate-quality evidence showed that there was little difference in the incidence of pancreatic fistula in PD between minimally invasive and open surgery, duct-to-mucosa and invaginated PJ, Roux-en-Y and conservative reconstruction, extended and standard lymphadenectomy, and in the incidence of pancreatic fistula in DP between fibrin sealant patch and no patch.</p><p><strong>Conclusions: </strong>This umbrella review found varying levels of evidence for the associations between different surgery-related risk factors for POPF. Given the wealth of existing evidence of relatively low quality, future research should focus on improving its credibility.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"442-459"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}