Mehdi Boubaddi, Arthur Marichez, Florian Pecquenard, Charlotte Maulat, Emmanuel Buc, Laurent Sulpice, Ahmet Ayav, Stéphanie Truant, Fabrice Muscari, Laurence Chiche, Christophe Laurent
{"title":"Liver venous deprivation (LVD) before extended hepatectomy: a French multicentric retrospective cohort.","authors":"Mehdi Boubaddi, Arthur Marichez, Florian Pecquenard, Charlotte Maulat, Emmanuel Buc, Laurent Sulpice, Ahmet Ayav, Stéphanie Truant, Fabrice Muscari, Laurence Chiche, Christophe Laurent","doi":"10.21037/hbsn-24-315","DOIUrl":"10.21037/hbsn-24-315","url":null,"abstract":"<p><strong>Background: </strong>Post-hepatectomy liver failure (PHLF) is the first cause of death after major hepatectomy, and future liver remnant (FLR) volume is the main factor predicting PHLF. Liver venous deprivation (LVD) via portal and hepatic vein embolization has been suggested to induce a better hypertrophy of the FLR than portal vein embolization. The aim of this retrospective multicentric study was to assess safety, feasibility and efficacity of LVD in a French national multicentric register.</p><p><strong>Methods: </strong>Between 2016 and 2023, LVD was performed in 7 expert centers, for patients with liver malignancies requiring major hepatectomy with an FLR percentage of total liver volume (FLR%) ≤25% for a healthy liver or <30% for a diseased liver. FLR volumetry was assessed before and 4 weeks after the procedure.</p><p><strong>Results: </strong>One hundred and ninety-two patients were included in the study. The technical success rate was 100% and severe complication rate post-LVD was 2.6% (5/192). The FLR% increased by 61.7% over an average of 27±9.7 days. Major hepatectomy was performed 40 days after LVD on 161 (83.8%) patients. Hepatectomy was not performed on 31 (16.2%) patients, mostly because of oncological progression. Severe postoperative complications (Clavien-Dindo grade ≥ IIIA) occurred in 21.1% (34/161) of patients. Postoperative mortality rate was 4.3% (7/161).</p><p><strong>Conclusions: </strong>This study is the largest to confirm that LVD is a safe, reproducible, efficient technique that induces rapid major FLR growth. However, this new technique needs to be standardized and harmonized between centers to ensure uniform results.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"937-949"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jamie Olapo Schnuck, Sardar Shahmir B Chauhan, Jonathan G Sham
{"title":"Surrogate endpoints in clinical trials: when is good...good enough?","authors":"Jamie Olapo Schnuck, Sardar Shahmir B Chauhan, Jonathan G Sham","doi":"10.21037/hbsn-24-607","DOIUrl":"10.21037/hbsn-24-607","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"1062-1064"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lingmin Jiang, Xin Huang, Xin Hua, Qiaoqiao Li, Yujing Zhang, Jun Wang, Shengping Li
{"title":"Treatment of locally advanced pancreatic cancer with irreversible electroporation and intraoperative radiotherapy.","authors":"Lingmin Jiang, Xin Huang, Xin Hua, Qiaoqiao Li, Yujing Zhang, Jun Wang, Shengping Li","doi":"10.21037/hbsn-24-526","DOIUrl":"10.21037/hbsn-24-526","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"1087-1090"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otto B van Leeuwen, Philipp Dutkowski, Diethard Monbaliu, Vincent E de Meijer
{"title":"Continuous normothermic machine perfusion of donor livers in the United States: the challenging road from the trial-world into the real-world.","authors":"Otto B van Leeuwen, Philipp Dutkowski, Diethard Monbaliu, Vincent E de Meijer","doi":"10.21037/hbsn-24-521","DOIUrl":"10.21037/hbsn-24-521","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"1022-1026"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recurrence-free or progression-free survival as a surrogate endpoint for overall survival in hepatobiliary-pancreatic cancers: would be associated with time change.","authors":"Ning Peng, Chuang Qin, Shao-Ping Liu, Jun-Liang Nong, Teng-Meng Zhong, Jian-Hong Zhong","doi":"10.21037/hbsn-24-597","DOIUrl":"10.21037/hbsn-24-597","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"1047-1050"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute coil migration in upper gastrointestinal bleeding.","authors":"Ziying Han, Kun He, Qingwei Jiang, Dong Wu","doi":"10.21037/hbsn-24-538","DOIUrl":"10.21037/hbsn-24-538","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"1091-1092"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emergency pancreaticoduodenectomy with portal vein reconstruction using polytetrafluoroethylene graft for fatal duodenal malignant ulcer bleeding due to pancreatic cancer: an aggressive, but precise surgical approach.","authors":"Bingcheng Meng, Weitao Chen, Banghao Xu, Hai Zhu, Jilong Wang, Zongrui Jin, Weimin Mao, Ling Zhang, Rui Song, Tingting Lu, Ya Guo, Zhang Wen","doi":"10.21037/hbsn-24-355","DOIUrl":"10.21037/hbsn-24-355","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"1077-1083"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhang Wen, Shuyue Tuo, Ying Liu, Jia Yuan, Yong Li, Lu Li, Shejiao Dai, Xinxing Tantai
{"title":"Validating the prognostic value of muscle changes in patients with cirrhosis undergoing transjugular intrahepatic portosystemic shunt.","authors":"Zhang Wen, Shuyue Tuo, Ying Liu, Jia Yuan, Yong Li, Lu Li, Shejiao Dai, Xinxing Tantai","doi":"10.21037/hbsn-24-418","DOIUrl":"10.21037/hbsn-24-418","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"1010-1014"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A European expert consensus surgical technique description for robotic hepatectomy.","authors":"Gabriela Pilz da Cunha, Daan J Lips, Jawad Ahmad, Niclas Kvarnström, Luca Aldrighetti, Mathieu D'Hondt, Jeroen Hagendoorn, Rutger-Jan Swijnenburg","doi":"10.21037/hbsn-23-510","DOIUrl":"10.21037/hbsn-23-510","url":null,"abstract":"<p><p>The robotic platform enables surgeons to operate with a similar level of freedom and control as in open surgery, while still providing the patient with the benefits of a minimally invasive approach. More centres continue to adopt robotic liver surgery however standardized training materials and consensus on the surgical technique are currently lacking. The availability of a standardized surgical protocol could benefit the further dissemination of the robotic approach while promoting safe and effective operating techniques. We present a comprehensive surgical technique description for robotic hepatectomy agreed upon by seven expert robotic liver surgeons in Europe. They contributed insights from their extensive experience with the robot to develop this report, highlighting the key steps and important considerations for performing robotic hepatectomy. We describe the surgical technique for four most common hepatectomy types with varying complexity: partial anterolateral resections, partial posterosuperior resections, left hepatectomy and right hepatectomy. This report encompasses recommendations from the experts, covering the preparatory steps such as patient selection and pre-operative imaging, and extending through to care in the postoperative phase. The step-by-step surgical technique description serves as a compendium of best practice methods presently utilized in robotic liver surgery. Although some variations in technique cannot be eliminated from practice, general recommendations in a structured form will help to homogenize the technique, safeguarding surgical quality. This paper aims to inform and advise surgeons in the process of adopting robotic liver surgery and can act as a starting point for further optimization and refinement of the technique.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"13 6","pages":"991-1006"},"PeriodicalIF":6.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}