{"title":"National impact and advantages of the robotic approach to liver surgery in the era of minimally invasive surgery.","authors":"Antoine Rouault, Yasmina Richa, Stéphanie Truant","doi":"10.21037/hbsn-2025-94","DOIUrl":"https://doi.org/10.21037/hbsn-2025-94","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"275-278"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Short- and long-term outcomes of laparoscopic versus open resection of perihilar cholangiocarcinoma: a propensity score-based analysis.","authors":"Zhi-Peng Liu, Yue Wang, Yu Pan, Xiao-Lin Zhao, Long-Fei Chen, Xue-Song Li, Xiao-Jun Wang, Jian-Wei Li, Xian-Yu Yin, Jie Bai, Yan-Qi Zhang, Hai-Su Dai, Zhi-Yu Chen, Shu-Guo Zheng","doi":"10.21037/hbsn-23-680","DOIUrl":"https://doi.org/10.21037/hbsn-23-680","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic resection (LR) of perihilar cholangiocarcinoma (pCCA) is still in the exploratory stage due to its exacting technical requirements, and its feasibility remains controversial. The objective of this study was to compare the short- and long-term outcomes of LR and open resection (OR) of pCCA.</p><p><strong>Methods: </strong>This study analyzed the data of pCCA patients who underwent LR or OR from January 2012 to January 2020 at Southwest Hospital. Inverse probability of treatment weighting (IPTW) and propensity score matching (PSM) were used to balance the baseline characteristics between the LR and OR groups. The short- and long-term outcomes were compared between the LR and OR groups.</p><p><strong>Results: </strong>Forty-five patients in the LR group and 243 in the OR group were analyzed. After IPTW and PSM, the amount of intraoperative blood loss, incidence of surgical site infections (SSIs), length of stay (LOS), and number of perioperative blood transfusions (PBTs) were significantly lower in the LR group than in the OR group (after IPTW: P<0.001, P=0.009, P=0.01, P<0.001 respectively; after PSM: P<0.001, P=0.003, P=0.03, P=0.04 respectively). Only after IPTW was the 30-day mortality rate significantly lower in the LR group than in the OR group (P=0.005). There was no significant difference in overall survival (OS) or recurrence-free survival (RFS) between the two groups after IPTW or PSM.</p><p><strong>Conclusions: </strong>LR of pCCA is an achievable procedure whose long-term outcomes are similar to those of OR, and LR outperforms OR in short-term outcomes such as intraoperative blood loss, SSI, LOS, 30-day mortality, and PBTs. It is believed that it is safe and feasible to treat pCCA with LR after rigorous patient selection.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"207-221"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High-volume living donor liver transplantation (LDLT): what the data tells us.","authors":"Berkay Demirors, Michele Molinari","doi":"10.21037/hbsn-2025-74","DOIUrl":"https://doi.org/10.21037/hbsn-2025-74","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"319-321"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Belkacem Acidi, Jean-Nicolas Vauthey, Hop S Tran Cao
{"title":"Transplantation for colorectal liver metastases: lessons from TransMet and future challenges.","authors":"Belkacem Acidi, Jean-Nicolas Vauthey, Hop S Tran Cao","doi":"10.21037/hbsn-2025-51","DOIUrl":"https://doi.org/10.21037/hbsn-2025-51","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"271-274"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Shifting paradigm of quality of life after pancreatoduodenectomy for pancreas cancer.","authors":"Kyuseok Im, Victoria V O'Connor","doi":"10.21037/hbsn-2025-79","DOIUrl":"https://doi.org/10.21037/hbsn-2025-79","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"316-318"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resmetirom as an important cornerstone of multidisciplinary management of metabolic dysfunction-associated steatohepatitis.","authors":"Kahei Au, Wah Yang","doi":"10.21037/hbsn-2024-716","DOIUrl":"https://doi.org/10.21037/hbsn-2024-716","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"290-294"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laparoscopic hepatectomy and near-infrared fluorescence based on the concept of \"biliary territory\" in the treatment of hepatolithiasis: a propensity score-matched study with videos.","authors":"Fengwei Gao, Qingyun Xie, Xin Zhao, Manyu Yang, Kangyi Jiang, Tianyang Mao, Jiayin Yang, Hong Wu","doi":"10.21037/hbsn-23-643","DOIUrl":"https://doi.org/10.21037/hbsn-23-643","url":null,"abstract":"<p><strong>Background: </strong>Hepatolithiasis, a common condition in East Asia, often requires surgical treatment. The aim of this study was to evaluate the safety and efficacy of near-infrared fluorescence (NIF)-guided laparoscopic hepatectomy (LH) using the 'biliary territory' concept for hepatolithiasis.</p><p><strong>Methods: </strong>This retrospective study included 97 patients who had undergone LH for hepatolithiasis between June 2018 and November 2022. The patients were divided into two groups based on whether intraoperative NIF-guided (n=31) or traditional white light (WL) laparoscopy (n=66) had been performed. Propensity score matching (PSM) was used to create 27 pairs for comparison. Perioperative outcomes, stone recurrence, and recurrence-free survival (RFS) were assessed.</p><p><strong>Results: </strong>Prior to PSM, NIF guidance was associated with reduced bleeding (P=0.01) and a lower conversion rate (P=0.001). After PSM, only the postoperative albumin concentration differed significantly between the two groups (P=0.003). The median duration of follow-up was 36 months. Before PSM, RFS differed significantly between the groups (P=0.009), whereas in the matched cohort, the stone recurrence rate was 33.3% in the WL group and 7.4% in the NIF group; however, the RFS did not differ significantly between these groups (P=0.09). Postoperative complications were identified by Cox regression analysis as an independent risk factor for recurrence (95% CI: 1.02-15.21, P=0.047).</p><p><strong>Conclusions: </strong>NIF-guided LH is a safe and effective approach to the treatment of hepatolithiasis, long-term outcomes being comparable to those of traditional techniques. Future studies should be larger and have longer follow-up.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"194-206"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chinese expert consensus on the diagnosis and treatment of hepatocellular carcinoma with microvascular invasion (2024 edition).","authors":"Juxian Sun, Yong Xia, Feng Shen, Shuqun Cheng","doi":"10.21037/hbsn-24-359","DOIUrl":"https://doi.org/10.21037/hbsn-24-359","url":null,"abstract":"<p><strong>Background: </strong>Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in China. Surgical resection is the preferred treatment for HCC, but the postoperative recurrence and metastasis rates are high. Current evidence shows that microvascular invasion (MVI) is an independent risk factor for postoperative recurrence and metastasis, but there are still many controversies about the diagnosis, classification, prediction, and treatment of MVI worldwide.</p><p><strong>Methods: </strong>Systematic literature reviews to identify knowledge gaps and support consensus statements and a modified Delphi method to develop evidence- and expert-based guidelines and finalization of the clinical consensus statements based on recommendations from a panel of experts.</p><p><strong>Results: </strong>After many discussions and revisions, the Chinese Association of Liver Cancer of the Chinese Medical Doctor Association organized domestic experts in related fields to form the \"Chinese expert consensus on the diagnosis and treatment of hepatocellular carcinoma with microvascular invasion (2024 edition)\" which included eight recommendations to better guide the prediction, diagnosis and treatment of HCC patients with MVI. The MVI pathological grading criteria as outlined in the \"Guidelines for Pathological Diagnosis of Primary Liver Cancer\" and the Eastern Hepatobiliary Surgery Hospital (EHBH) nomogram for predicting MVI are highly recommended.</p><p><strong>Conclusions: </strong>We present an expert consensus on the diagnosis and treatment of MVI and potentially improve recurrence-free survival (RFS) and overall survival (OS) for HCC patients with MVI.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"246-266"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing the management of hepatocellular carcinoma: surrogate markers and predictive biomarkers for survival on immunotherapy.","authors":"Naoshi Nishida","doi":"10.21037/hbsn-2025-78","DOIUrl":"https://doi.org/10.21037/hbsn-2025-78","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"311-315"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diamantis I Tsilimigras, Ioannis Ntanasis-Stathopoulos, Dimitrios Moris
{"title":"Recurrence beyond Milan criteria following liver resection for early-stage hepatocellular carcinoma: incidence, prediction and implications for treatment selection.","authors":"Diamantis I Tsilimigras, Ioannis Ntanasis-Stathopoulos, Dimitrios Moris","doi":"10.21037/hbsn-2025-45","DOIUrl":"https://doi.org/10.21037/hbsn-2025-45","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 2","pages":"305-307"},"PeriodicalIF":6.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}