Gynecological Endocrinology最新文献_第5页

World's first case report of live birth following autologous ovarian tissue cryopreservation and transplantation in a patient with colon carcinoma. 世界首例结肠癌患者自体卵巢组织冷冻保存和移植后活产的病例报告。

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-10-05 DOI: 10.1080/09513590.2026.2741962

Xiangyan Ruan, Juan Du, Muqing Gu, Fengyu Jin, Jing Jin, Yanglu Li, Jiaojiao Cheng, Yanqiu Li, Weimin Kong, Qi Zhang, Zecheng Wang, Mingzhen Zhang, Anming Liu, Lingling Jiang, Yuejiao Wang, Matthias Korell, Markus Montag, Jana Bender Liebenthron, Alfred O Mueck

{"title":"World's first case report of live birth following autologous ovarian tissue cryopreservation and transplantation in a patient with colon carcinoma.","authors":"Xiangyan Ruan, Juan Du, Muqing Gu, Fengyu Jin, Jing Jin, Yanglu Li, Jiaojiao Cheng, Yanqiu Li, Weimin Kong, Qi Zhang, Zecheng Wang, Mingzhen Zhang, Anming Liu, Lingling Jiang, Yuejiao Wang, Matthias Korell, Markus Montag, Jana Bender Liebenthron, Alfred O Mueck","doi":"10.1080/09513590.2026.2741962","DOIUrl":"https://doi.org/10.1080/09513590.2026.2741962","url":null,"abstract":"Objective: This article reports on the world's first live birth after ovarian tissue cryopreservation and transplantation (OTCT) in a patient with colon cancer.Methods: A 29-year-old unmarried nulliparous patient underwent ovarian tissue cryopreservation before chemotherapy. After chemotherapy-induced premature ovarian insufficiency, she received the first transplantation of six thawed ovarian cortex strips. Despite normal ovarian function being maintained for over 2 years, she requested and underwent a second transplantation with another six strips to maximize her chances of pregnancy.Results: After the first transplantation, she resumed spontaneous menstruation with restored ovarian function, which was remained functional for 28 months until the second transplantation. Following the second transplantation, she conceived spontaneously without assisted reproductive technology two months after grafting. Routine prenatal examinations showed normal fetal development without abnormalities. She delivered a healthy baby girl weighing 2785 g with Apgar scores of 8/9 at 1 and 5 min.Conclusions: This case demonstrates the feasibility and safety of OTCT for fertility and ovarian function preservation in patients with colon cancer.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2741962"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149108890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of serum creatinine-to-albumin ratio with hyperandrogenemia and low sex hormone-binding globulin in women of reproductive age: a cross-sectional analysis of NHANES 2013-2016. 育龄妇女血清肌酐与白蛋白比值与高雄激素血症和低性激素结合球蛋白的相关性：NHANES 2013-2016的横断面分析

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-10-17 DOI: 10.1080/09513590.2026.2750772

Qianying Yang

{"title":"Association of serum creatinine-to-albumin ratio with hyperandrogenemia and low sex hormone-binding globulin in women of reproductive age: a cross-sectional analysis of NHANES 2013-2016.","authors":"Qianying Yang","doi":"10.1080/09513590.2026.2750772","DOIUrl":"https://doi.org/10.1080/09513590.2026.2750772","url":null,"abstract":"Background: Hyperandrogenemia (HA) and low sex hormone-binding globulin (SHBG) are core features of polycystic ovary syndrome. The creatinine-to-albumin ratio (CAR), a simple renal-nutritional marker linked to female infertility, has not been studied in relation to HA or low SHBG.Objective: To examine the association of CAR with low SHBG and HA, defined by the free androgen index (FAI), in U.S. women of reproductive age.Methods: In this cross-sectional analysis of NHANES 2013-2016, we included 683 women aged 18-49 years. CAR (serum creatinine/albumin) was categorized into tertiles; low SHBG was defined as < 30 nmol/L and HA as FAI ≥ 75th percentile. Survey-weighted multivariable logistic regression was used, with multiple imputation (m = 5) as a sensitivity analysis.Results: In Model 1 (age, race/ethnicity, education, income), the highest CAR tertile was associated with low SHBG (OR 2.93, 95% CI 1.49-5.75; P = 0.003; P for trend = 0.004) and FAI-defined HA (OR 1.87, 95% CI 1.05-3.34; P = 0.036; P for trend = 0.044). In Model 2 (plus smoking, BMI, low HDL-C), associations attenuated (OR 1.95, 95% CI 1.05-3.64 for low SHBG; 1.24, 95% CI 0.65-2.34 for HA-FAI). HA defined by total testosterone was not associated with CAR.Conclusion: Higher CAR was associated with low SHBG and FAI-defined HA after demographic adjustment, with attenuation after metabolic adjustment, suggesting confounding by shared metabolic factors. As CAR derives from routine laboratory tests, it may be a practical marker of reproductive metabolic risk; the cross-sectional design precludes causal inference.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2750772"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The GPR120 as a novel predictive and diagnostic marker for preeclampsia in the first trimester. GPR120作为早期妊娠子痫前期的一种新的预测和诊断标志物。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-02-25 DOI: 10.1080/09513590.2026.2636355

Mengyuan Lin, Yi-Yuan Jin, Qingwen He, Zhenhong Wu

{"title":"The GPR120 as a novel predictive and diagnostic marker for preeclampsia in the first trimester.","authors":"Mengyuan Lin, Yi-Yuan Jin, Qingwen He, Zhenhong Wu","doi":"10.1080/09513590.2026.2636355","DOIUrl":"https://doi.org/10.1080/09513590.2026.2636355","url":null,"abstract":"Objective: This study aimed to determine if there was a change in serum G protein-coupled receptor 120 (GPR120) level and develop a nomogram model that accurately predicted the risk of preeclampsia (PE) in the first trimester.Methods: A total of 250 pregnant women were included in our prospective cohort study from January 2023 to July 2024. We measured the level of GPR120, and maternal demographics and clinical features were retrieved. Optimization of variable selection was achieved. We developed a nomogram based on multivariate logistic regression to predict the risk of pulmonary embolism (PE), incorporating eight selected predictive indicators. The AUC and calibration plots were utilized to assess the discrimination and calibration of the nomogram. For assessing the clinical advantages and usefulness of the two prediction models, the DCA, IDI, and NRI were utilized.Results: The GPR120 expression level in the first trimester was significantly elevated in women who later developed PE (P < 0.001). The nomogram demonstrated excellent discriminatory power in predicting PE in both the training and validation cohort. Calibration of the nomogram remained satisfactory in both the training and validation cohorts. The NRI values and IDI demonstrated that the performance of the developed nomogram was remarkably superior to that of the Model 2 (P < 0.05). The nomogram's clinical usefulness was validated by the DCA.Conclusions: GPR120 expression is significantly increased in early pregnancy of PE patients. The nomogram exhibited predictive capability for PE development but needs larger, multicenter cohorts for validation.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2636355"},"PeriodicalIF":1.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147305061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of key genes in recurrent pregnancy loss related to obesity. 与肥胖相关的复发性妊娠丢失关键基因的鉴定。

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-04-21 DOI: 10.1080/09513590.2026.2659978

Haixia Mi, Lingling Zhao, Junhong Guo

{"title":"Identification of key genes in recurrent pregnancy loss related to obesity.","authors":"Haixia Mi, Lingling Zhao, Junhong Guo","doi":"10.1080/09513590.2026.2659978","DOIUrl":"10.1080/09513590.2026.2659978","url":null,"abstract":"Objective: The underlying mechanism of recurrent pregnancy loss (RPL) is still not fully understood. We aimed to identify the key genes involved in the process by which obesity influences RPL.Methods: RPL and obesity data were retrieved from the GEO database. The differentially expressed genes (DEGs) between disease and normal samples among RPL and obesity were selected. Through intersecting the above DEGs, important DEGs were obtained. GO and KEGG analyses were used to analyze the function of these important genes. Two algorithms (LASSO and SVM) and receiver operator characteristic (ROC) analysis were used to optimize the DEGs. Furthermore, the immune infiltration and single gene enrichment analysis were performed to explore the correlations between key biomarkers and immune cells.Results: A total of 1857 RPL-related DEGs and 2880 obesity-related DEGs were selected, respectively. Through intersecting the above two parts of DEGs, 100 important genes were obtained, which were involved in immune response processes such as the EGFR tyrosine kinase inhibitor resistance JAK-STAT signaling pathway, and T cell receptor signaling pathway. Through LASSO, SVM, and ROC analyses, five down-regulated optimal genes in RPL were finally considered as biomarkers in obesity-related RPL: GIPR, KRTAP4-11, NFU1, OPN4, and PRMT7. The five biomarkers showed effective diagnostic ability in RPL, with AUC above 0.8. Furthermore, eosinophils, CD56 bright natural killer cells, and monocytes were significantly correlated with the five biomarkers.Conclusion: This study identified five effectively diagnostic genes and explored their correlations with immune cells, providing indications for the following development of diagnostic tools and potential mechanism exploration.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2659978"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147769895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of regional fat distribution indicators with infertility in women: insights from the 2013-2018 NHANES. 区域脂肪分布指标与女性不孕症的关联：来自2013-2018年NHANES的见解

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-05-09 DOI: 10.1080/09513590.2026.2670809

Luming Chen, Fangxiang Mu, Tianyu He, Fang Wang

{"title":"Association of regional fat distribution indicators with infertility in women: insights from the 2013-2018 NHANES.","authors":"Luming Chen, Fangxiang Mu, Tianyu He, Fang Wang","doi":"10.1080/09513590.2026.2670809","DOIUrl":"10.1080/09513590.2026.2670809","url":null,"abstract":"Background: Female infertility is multifactorial, with adiposity and regional fat distribution hypothesized as contributors, though evidence using detailed fat measures is limited. This study aims to examine the association between fat distribution indicators and female infertility in a nationally representative sample.Methods: This retrospective cross-sectional study analyzed NHANES 2013-2018 data from 2,531 women aged 20-45. Infertility was defined by self-reported difficulty conceiving ≥ 12 months or seeking fertility care. Exposures included body mass index (BMI) and DXA-based measures: total percent fat (TPF), android percent fat (APF), gynoid percent fat (GPF), android fat/gynoid fat ratio (AGR), visceral fat/total fat (VPF), subcutaneous fat/total fat (SPF), and visceral fat/subcutaneous fat ratio (VSR). Multivariable logistic regression was used to assess associations, and sensitivity analyses were performed to evaluate robustness.Results: In multivariable-adjusted models, TPF, APF, AGR, and BMI were modestly associated with higher odds of infertility (TPF: OR = 1.02, 95%CI: 1.00-1.05; APF: OR = 1.03, 95%CI: 1.01-1.04; AGR: OR = 1.02, 95%CI: 1.01-1.03; BMI: OR = 1.02, 95%CI: 1.01-1.04). Smooth curve fitting suggested a generally monotonic positive pattern for these associations. Associations were broadly similar across subgroups, although some subgroup interactions were observed.Conclusion: In this analysis, TPF, APF, AGR, and BMI showed modest associations with infertility, which should not be interpreted causally. Although associations were generally consistent across subgroups, subgroup-specific heterogeneity cannot be excluded.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2670809"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147856272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diabetes in Turner syndrome: a distinct entity demanding specific therapeutic strategies. 糖尿病特纳综合征：一个独特的实体需要特定的治疗策略。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-01-20 DOI: 10.1080/09513590.2026.2614166

Francisco Álvarez-Nava

引用次数: 0

Intrauterine platelet-rich plasma infusion with hormone replacement therapy improves menstrual and pregnancy outcomes in thin endometrium patients undergoing frozen-thawed embryo transfer. 宫内富血小板血浆输注激素替代疗法改善薄子宫内膜患者接受冻融胚胎移植的月经和妊娠结局。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-01-06 DOI: 10.1080/09513590.2025.2610084

Xiaofeng Zhu, Xiaoyang Deng, Li Li, Xia Zhao, Yanhua Guo

{"title":"Intrauterine platelet-rich plasma infusion with hormone replacement therapy improves menstrual and pregnancy outcomes in thin endometrium patients undergoing frozen-thawed embryo transfer.","authors":"Xiaofeng Zhu, Xiaoyang Deng, Li Li, Xia Zhao, Yanhua Guo","doi":"10.1080/09513590.2025.2610084","DOIUrl":"https://doi.org/10.1080/09513590.2025.2610084","url":null,"abstract":"Objective: To evaluate the effect of intrauterine infusion of platelet-rich plasma (PRP) on luteal support and pregnancy outcomes in patients with thin endometrium undergoing frozen-thawed embryo transfer (FET).Methods: A total of 160 patients with thin endometrium undergoing FET from March 2023 to March 2024 were assigned to the observation group (PRP infusion, n = 80) or the control group (conventional treatment, n = 80). All patients underwent hormone replacement therapy cycles,with PRP infused on days 9, 11, and 13 in the observation group. Outcomes included endometrial thickness, uterine hemodynamic parameters (PI, RI), PBAC-assessed menstrual volume, pregnancy outcomes, and embryology-related variables. Logistic regression identified independent factors associated with clinical pregnancy. Adverse events were also recorded.Results: Post-treatment, the observation group had greater endometrial thickness and lower PI and RI values than the control group. PBAC scores, clinical pregnancy rate (36.25% vs. 21.25%), and live birth rate (25.00% vs. 12.50%) were significantly higher, while preterm birth rate did not differ. Embryo transfer-related variables were comparable between groups. Multivariate analysis identified PRP infusion and endometrial thickness at transfer as independent protective factors for clinical pregnancy, whereas advanced age was an unfavorable factor. No obvious adverse events occurred.Conclusion: PRP infusion enhances endometrial receptivity by improving thickness and blood perfusion, thereby increasing pregnancy and live birth rates in thin endometrium patients undergoing FET. It is safe and may be used as an effective adjunct in endometrial preparation.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2610084"},"PeriodicalIF":1.7,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Statement of retraction: Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome. 撤回声明：在一项随机对照试验中，肌醇和褪黑素对肌醇改善多囊卵巢综合征患者体外受精的影响。

IF 1.7 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-02-02 DOI: 10.1080/09513590.2026.2625568

引用次数: 0

Relugolix combination therapy in symptomatic adenomyosis and uterine fibroids: a case series. 瑞路高利联合治疗症状性bbb和子宫肌瘤：一个病例系列。

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-04-18 DOI: 10.1080/09513590.2026.2659439

Stefania Saponara, Maurizio Nicola D'Alterio, Stefano Di Michele, Caterina Chilà, Antonio Maiorana, Michele Vignali, Ludovico Muzii, Stefano Angioni

{"title":"Relugolix combination therapy in symptomatic adenomyosis and uterine fibroids: a case series.","authors":"Stefania Saponara, Maurizio Nicola D'Alterio, Stefano Di Michele, Caterina Chilà, Antonio Maiorana, Michele Vignali, Ludovico Muzii, Stefano Angioni","doi":"10.1080/09513590.2026.2659439","DOIUrl":"10.1080/09513590.2026.2659439","url":null,"abstract":"Objective: To evaluate the clinical efficacy and safety of a once-daily oral fixed-dose combination of relugolix 40 mg, estradiol 1 mg, and norethisterone acetate 0.5 mg in women with symptomatic adenomyosis coexisting with uterine fibroids.Methods: This case series included six women with uterine fibroids and concomitant adenomyosis, diagnosed by transvaginal ultrasound according to MUSA criteria. All patients received continuous treatment for 12 months. Clinical outcomes included changes in dysmenorrhea and pelvic pain assessed by the Visual Analogue Scale (VAS), menstrual blood loss evaluated through the Pictorial Blood Assessment Chart (PBAC), and hemoglobin levels. Ultrasonographic assessment measured uterine volume and adenomyosis-related features before and after treatment.Results: All patients achieved complete resolution of dysmenorrhea and chronic pelvic pain, with VAS scores reduced to zero. Menstrual bleeding ceased in all cases (PBAC = 0), and hemoglobin levels improved after 12 months. Ultrasound examination demonstrated a reduction in uterine volume ranging from 8.6% to 58.3%, along with partial regression of direct adenomyotic features. No adverse events or treatment discontinuations were reported during follow-up.Conclusions: Relugolix/estradiol/norethisterone acetate combination therapy was effective, well-tolerated, and associated with consistent clinical and sonographic improvement in women with adenomyosis and coexisting fibroids. Future larger-scale, controlled studies with extended follow-up are warranted to validate these findings.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2659439"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147722716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The global impact of female infertility: regional disparities and future projections from the GBD 2021 study. 女性不育的全球影响：GBD 2021研究的区域差异和未来预测

IF 3 4区医学

Gynecological Endocrinology Pub Date : 2026-12-31 Epub Date: 2026-07-22 DOI: 10.1080/09513590.2026.2697103

Bingxue Ning, Xiaojing Wang, Mengjie Zhang, Su Nan, Raowan Bur, Haozhe Ma, Kun Liu, Xiaolin La

{"title":"The global impact of female infertility: regional disparities and future projections from the GBD 2021 study.","authors":"Bingxue Ning, Xiaojing Wang, Mengjie Zhang, Su Nan, Raowan Bur, Haozhe Ma, Kun Liu, Xiaolin La","doi":"10.1080/09513590.2026.2697103","DOIUrl":"https://doi.org/10.1080/09513590.2026.2697103","url":null,"abstract":"Objective: Female infertility is an escalating global health challenge. Utilizing data from the Global Burden of Disease Study 2021, this study analyzed the spatiotemporal distribution of female infertility (1990-2021) and projected trends through 2050.Methods: We evaluated prevalence, disability-adjusted life years (DALYs), and age-standardized rates across 204 countries, stratified by Socio-demographic Index (SDI). Temporal trends were quantified using Estimated Annual Percentage Change (EAPC), and future burdens were forecasted via Bayesian Age-Period-Cohort models.Results: Global female infertility cases surged by 84.4%, rising from 59.69 million in 1990 to 110.09 million in 2021, with the age-standardized prevalence rate (ASPR) trending upward (EAPC=0.70). While High-middle and Middle SDI regions bore the largest absolute burden-driven by persistent infections and metabolic risks-High SDI regions exhibited the steepest increase (EAPC=1.43). This rapid rise in developed nations aligns with delayed childbearing, evidenced by a peak prevalence shift to the 40-44 age group, contrasting with the global peak at 35-39 years. Projections indicate a continued ascent in burden across all cohorts through 2050.Conclusions: The global burden of female infertility is rising and spatially distinct. Transitioning economies face high baseline rates, yet developed nations show the fastest growth, demanding urgent action. Strategies must be tailored to regional drivers: prioritizing infection control and metabolic health in middle-income settings, and fertility support policies in high-income regions.","PeriodicalId":12865,"journal":{"name":"Gynecological Endocrinology","volume":"42 1","pages":"2697103"},"PeriodicalIF":3.0,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148561742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0