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[Reproductive techniques and concepts of psychosomatic medicine]. [生殖技术与心身医学概念]。
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-12-03 DOI: 10.1159/000154807
Ingrid Kowalcek
{"title":"[Reproductive techniques and concepts of psychosomatic medicine].","authors":"Ingrid Kowalcek","doi":"10.1159/000154807","DOIUrl":"https://doi.org/10.1159/000154807","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to assess the expectations of the patients regarding prenatal examination and assisted reproductive treatment.</p><p><strong>Methods: </strong>The first sample included patients and their partners at the commencement of assisted reproductive treatment. The couples were asked to predict the success of in vitro fertilization on a scale ranging from 0 to 100%. The second sample included pregnant women and their partners prior to prenatal examination (level III). These couples were asked what expectations they had regarding the prenatal examination.</p><p><strong>Results: </strong>On average, 57% of the women and 61% of their partners expected a successful pregnancy in the course of the ongoing reproductive treatment. The expectations at the prenatal examination indicated that both the women and their partners wished, in the first instance, a reassuring outcome and a positive diagnosis of pregnancy. Lower down the scale in third and fourth position were safety and assurance.</p><p><strong>Discussion: </strong>The patients focused their expectations mainly on the technical possibilities of the reproductive techniques. It is therefore necessary in psychosomatic medicine to introduce personal concepts for discussion in order to avoid being subordinated to prevalent facts.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 4","pages":"231-3"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000154807","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27911864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[High-risk situation - which is the best chemotherapy?]. [高危情况——哪种化疗最好?]
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-06-17 DOI: 10.1159/000127393
Gunter von Minckwitz
{"title":"[High-risk situation - which is the best chemotherapy?].","authors":"Gunter von Minckwitz","doi":"10.1159/000127393","DOIUrl":"https://doi.org/10.1159/000127393","url":null,"abstract":"<p><p>High-risk situations in early breast cancer concern patients with less than 3 involved lymph nodes but additional risk factors as well as patients with more than 3 involved lymph nodes. For the first group, new risk assessment methods to better identify the need for chemotherapy with or without a taxane or with a taxane instead of an anthracycline are needed. For the second group, further improvement of anthracycline- or taxane-containing chemotherapy regimens is warranted. Current approaches include the sequential or simultaneous use of these groups of agents, the combination with antimetabolites, antibodies or small molecules, the neoadjuvant use of chemotherapy as well as dose-dense and dose-escalated chemotherapy regimens.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 3","pages":"118-29"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000127393","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27510375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Androgens and insulin--two key players in polycystic ovary syndrome. Recent concepts in the pathophysiology and genetics of polycystic ovary syndrome. 雄激素和胰岛素——多囊卵巢综合征的两个关键因素。多囊卵巢综合征病理生理学和遗传学的新概念。
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-01-17 DOI: 10.1159/000111465
Andreas N Schuring, Nicole Schulte, Barbara Sonntag, Ludwig Kiesel
{"title":"Androgens and insulin--two key players in polycystic ovary syndrome. Recent concepts in the pathophysiology and genetics of polycystic ovary syndrome.","authors":"Andreas N Schuring,&nbsp;Nicole Schulte,&nbsp;Barbara Sonntag,&nbsp;Ludwig Kiesel","doi":"10.1159/000111465","DOIUrl":"https://doi.org/10.1159/000111465","url":null,"abstract":"<p><p>Androgens and insulin are endocrine key players in the pathophysiology of polycystic ovary syndrome (PCOS), a heterogenic condition of unexplained etiology and a suspected genetic background. Androgens mediate the clinical phenotype of the disease. Therefore,all criteria of the recent PCOS consensus definition are based on their biological effects. Insulin resistance, followed by compensatory hyperinsulinemia, is frequently found in patients with PCOS. Insulin resistance is correlated with a risk of metabolic complications of PCOS, and recent research has focused on possible long-term health consequences of the syndrome. Newest molecular genetic findings at the receptor level of both androgens and insulin support their pivotal role in PCOS. These results could help to better characterize the heterogenic disorder, enabling a refinement of existing individualized therapeutic strategies.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 1","pages":"9-15"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000111465","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41077097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 51
[In vitro maturation--a new therapeutic option in polycystic ovary syndrome]. [体外成熟——多囊卵巢综合征的一种新的治疗选择]。
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-01-17 DOI: 10.1159/000111467
Michael von Wolff, Inge Eberhardt, Thomas Strowitzki
{"title":"[In vitro maturation--a new therapeutic option in polycystic ovary syndrome].","authors":"Michael von Wolff,&nbsp;Inge Eberhardt,&nbsp;Thomas Strowitzki","doi":"10.1159/000111467","DOIUrl":"https://doi.org/10.1159/000111467","url":null,"abstract":"velopment of a new technique, called in vitro maturation (IVM), in which immature oozytes can be obtained without stimulation by exogenous gonadotropins, thereby avoiding the risk of an ovarian hyperstimulation syndrome. The introduction of IVM in Germany in 2005 has revealed a pregnancy rate in young patients of around 15% per treatment cycle. Even though the pregnancy rate is lower than in regular IVF treatments, its success rate is acceptable in PCOS patients as the risk of developing an ovarian hyperstimulation syndrome is avoided. IVM is therefore a new therapy that can be recommended in young PCOS patients. Copyright © 2008 S. Karger AG, Basel","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 1","pages":"24-30"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000111467","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41077099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
[Adjuvant therapy of breast cancer with trastuzumab]. [曲妥珠单抗辅助治疗乳腺癌]。
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-06-17 DOI: 10.1159/000127395
Christine Beneder, Christian Marth
{"title":"[Adjuvant therapy of breast cancer with trastuzumab].","authors":"Christine Beneder,&nbsp;Christian Marth","doi":"10.1159/000127395","DOIUrl":"https://doi.org/10.1159/000127395","url":null,"abstract":"<p><p>With the approval of trastuzumab (Herceptin) in 1998, a new era of breast cancer treatment has been heralded. This antibody is directed at the intracellular domain of a member of the epidermal growth factor receptor family, the so-called HER2 receptor. About 25-30% of all breast cancers overexpress this factor, which is associated with a more unfavorable prognosis. Trastuzumab is indicated for patients whose tumor overexpresses HER2. All previous studies on the adjuvant therapy with trastuzumab show very consistent results and provide evidence that the risk of recurrence can be reduced by half by the antibody. Nevertheless, there are still numerous open and controversially discussed questions concerning the use of trastuzumab in adjuvant therapy.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 3","pages":"138-42"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000127395","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27509783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Family and career planning in young physicians]. [青年医生的家庭与职业规划]。
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-12-03 DOI: 10.1159/000154808
Barbara Buddeberg-Fischer, Martina Stamm, Richard Klaghofer
{"title":"[Family and career planning in young physicians].","authors":"Barbara Buddeberg-Fischer,&nbsp;Martina Stamm,&nbsp;Richard Klaghofer","doi":"10.1159/000154808","DOIUrl":"https://doi.org/10.1159/000154808","url":null,"abstract":"<p><strong>Objectives: </strong>The study investigates in what way physicians integrate their desire to have children into their career planning.</p><p><strong>Methods: </strong>Within the framework of a prospective cohort study of Swiss medical school graduates on career development of young physicians, beginning in 2001, 534 participants (285 women, 249 men) were assessed in January 2007, in terms of having children, planning to have children, the career aspired to and the work-family balance used or planned.</p><p><strong>Results: </strong>Among the study participants, 19% (54) of the women and 24% (59) of the men have children. Of the others 88% plan to start a family in the future. Female physicians with children are less advanced in their careers than women without children; for male physicians no such difference can be observed. Of the female physicians with children or the desire for children 42% aspire to work in a practice, 28% to a clinical and only 4% to an academic career. Of the male physicians with children or the desire for children one third aspire to work in a practice, one third to a clinical and 14% to an academic career. The preferred model of work repartition of female physicians with children is father full time/mother part time or both parents part time; the preferred model of male physicians is father full time/mother part time or not working.</p><p><strong>Conclusion: </strong>Children are an important factor in the career and life planning of physicians, female physicians paying more attention to an even work-family balance than male physicians.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 4","pages":"234-40"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000154808","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27911865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
[Botulinum toxin A in the treatment of the idiopathic overactive bladder. Expert letter Nr. 25 from 28 August 2007]]. 肉毒毒素A治疗特发性膀胱过动症。2007年8月28日第25号专家信函]]。
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-01-17 DOI: 10.1159/000111471
{"title":"[Botulinum toxin A in the treatment of the idiopathic overactive bladder. Expert letter Nr. 25 from 28 August 2007]].","authors":"","doi":"10.1159/000111471","DOIUrl":"https://doi.org/10.1159/000111471","url":null,"abstract":"• Therapieresistente überaktive Harnblase (gemäss Definition der International Continence Society: «overactive bladder», mit urodynamisch nachgewiesener Detrusorüberaktivität, mit oder ohne Inkontinenz) • Therapieresistente hypersensitive, hypokapazitäre Harnblase mit persistierendem imperativem Dranggefühl, Pollakisurie, Nykturie (Therapieresistenz = Symptome nicht wirksam therapierbar selbst mit maximalen Dosierungen von herkömmlichen Therapien wie Anticholinergika, Verhaltenstraining und physikalischen Therapien) • Bei nicht tolerierbaren Nebenwirkungen, hervorgerufen durch Anticholinergika (Xerostomie, Obstipation, Nausea, Müdigkeit und Konzentrationsschwäche) • Kontraindikationen einer Anticholinergikatherapie Leidensdruck des Patienten/der Patientin und fachärztliche Beurteilung der Wahrscheinlichkeit eines Behandlungserfolgs auf der Basis urodynamischer und klinischer Untersuchungen sollen über die Indikation zur Botulinumtoxininjektion entscheiden. Zur Behandlung befähigt sind Zentren mit urodynamischer Ausrüstung und entsprechender Expertise.","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 1","pages":"47-50"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000111471","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41076251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Laparoscopic ovarian drilling in polycystic ovary syndrome to achieve ovulatory cycles]. 【腹腔镜卵巢钻孔治疗多囊卵巢综合征实现排卵周期】。
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-01-17 DOI: 10.1159/000111464
Thomas Strowitzki
{"title":"[Laparoscopic ovarian drilling in polycystic ovary syndrome to achieve ovulatory cycles].","authors":"Thomas Strowitzki","doi":"10.1159/000111464","DOIUrl":"https://doi.org/10.1159/000111464","url":null,"abstract":"Die operative Behandlung des polyzystischen Ovarsyndroms ist als laparoskopische ovarielle Thermokoagulation (Drilling, LOD) ein weit verbreitetes Verfahren. Der Stellenwert ist noch unklar. Langzeiterfolge mit ovulatorischen Zyklen über einen Nachbeobachtungszeitraum von bis zu 9 Jahren sind beschrieben. Schwangerschaftsraten sind unter LOD vergleichbar einer niedrig dosierten Gonadotropinstimulation über 3–6 Zyklen. Nachteile des LOD sind die Notwendigkeit eines operativen Eingriffs und postoperative Adhäsionsbildung. Bei Patientinnen mit schlechter Ansprechrate kann LOD die ovarielle Stimulierbarkeit verbessern.","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 1","pages":"3-8"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000111464","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41077096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The polycystic ovary syndrome--metabolic consequences]. 【多囊卵巢综合征——代谢后果】。
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-01-17 DOI: 10.1159/000111466
Susanne Tan, Susanne Hahn, Onno E Janssen
{"title":"[The polycystic ovary syndrome--metabolic consequences].","authors":"Susanne Tan,&nbsp;Susanne Hahn,&nbsp;Onno E Janssen","doi":"10.1159/000111466","DOIUrl":"https://doi.org/10.1159/000111466","url":null,"abstract":"Objective: The polycystic ovary syndrome (PCOS) is often associated with insulin resistance. This article aims to demonstrate the metabolic consequences following insulin resistance in PCOS-affected women and the need of intervention. Methods: A systematic review of the published literature, using the MEDLINE database, was conducted to identify studies assessing the prevalence of insulin resistance and cardiovascular risk factors in PCOS patients. Results: Besides the classic cardiovascular risk factors like insulin resistance, visceral obesity, dyslipidemia and hypertension, patients with PCOS also show elevated markers of chronic inflammation and are often suffering from subclinical atherosclerosis. Conclusions: Patients with PCOS are at high risk for developing impaired glucose tolerance and show a distinct cardiovascular risk profile. Therefore, the early identification of affected patients and the institution of lifestyle changes or pharmacological treatments may help delay the progression to type 2 diabetes mellitus and cardiovascular disease.","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 1","pages":"16-23"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000111466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41077098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Magnetic resonance tomography in the diagnostics of breast implants: a survey]. 磁共振断层扫描在乳房植入物诊断中的应用综述
Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-04-16 DOI: 10.1159/000118935
E A Hauth, O Hoffmann, T Zadow-Eulerich, R Kimmig, M Forsting
{"title":"[Magnetic resonance tomography in the diagnostics of breast implants: a survey].","authors":"E A Hauth,&nbsp;O Hoffmann,&nbsp;T Zadow-Eulerich,&nbsp;R Kimmig,&nbsp;M Forsting","doi":"10.1159/000118935","DOIUrl":"https://doi.org/10.1159/000118935","url":null,"abstract":"<p><p>This review article describes the procedure of magnetic resonance (MR) mammography in patients with breast implants. The spectrum of breast implants in MR imaging and local implant complications are illustrated. MR mammography should be used for the diagnosis of implant complications and suspected malignant lesions in patients with breast implants.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"48 2","pages":"76-83"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000118935","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27398537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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