Green Synthesis and Catalysis最新文献_第6页

Chemoselective synthesis of α-carboline derivatives via hypervalent iodine-catalyzed [3+3] annulation under metal-free conditions 在无金属条件下通过高价碘催化 [3+3] 环化化学选择性合成 α-咔啉衍生物

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2023.01.002

Shuowen Wang , Rong Li , Shanping Chen , Guojiang Mao , Wen Shao , Guo-Jun Deng

引用次数: 0

Rh(II) catalyzed efficient sigmatropic rearrangement reaction of pyridotriazoles and sulfides Rh(II)催化吡啶三唑和硫化物的高效西格玛重排反应

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2023.04.004

Yuting Chen , Guanghui Lv , Zhiyang Li , Meiling Ye , Tianle Huang , Li Hai , Yong Wu

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Photochemical nitrene transfer reactions of iminoiodinanes with sulfoxides 亚氨基碘烷与硫氧化物的光化学芘转移反应

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2024.05.001

Xuemei Zhao, Zhiyuan Tang, Linlin Shi, Yujing Guo, Rene M. Koenigs, Xinqi Hao

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Direct C(sp3)-H functionalization with thiosulfonates via photoredox catalysis 通过光氧化催化实现硫代磺酸盐与 C(sp3)-H 的直接官能化

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2024.05.003

Linfeng Liu, Yujian Pang, Canliang Ma, Daiqing Zhou, Wenjie Zhang, Jin Huang, Jie Sun, Jiangkai Qiu, Yihuan Liu, Lei Shen, Zhenjiang Li, Kai Guo

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Ir-catalyzed photoredox cascade radical annulation reactions toward phosphinimides bearing quaternary carbon center at room temperature 室温下铱催化光氧化级联自由基环化反应生成含季碳中心的膦酰亚胺

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2024.04.006

Shujuan Xu, Fang Xun, Jiapian Huang, Jie Wu, Zhiyuan Chen

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Biocatalytic stereoselective synthesis of methyl mandelates by engineering a cytochrome P450 hydroxylase 通过细胞色素 P450 羟化酶的生物催化立体选择性合成扁桃酸甲酯

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2023.01.005

Lingzhi Xie , Yun Zhang , Ruyue Zhang , Haibo Cui , Baodong Cui , Wenyong Han , Nanwei Wan , Zhi Li , Yongzheng Chen

{"title":"Biocatalytic stereoselective synthesis of methyl mandelates by engineering a cytochrome P450 hydroxylase","authors":"Lingzhi Xie , Yun Zhang , Ruyue Zhang , Haibo Cui , Baodong Cui , Wenyong Han , Nanwei Wan , Zhi Li , Yongzheng Chen","doi":"10.1016/j.gresc.2023.01.005","DOIUrl":"10.1016/j.gresc.2023.01.005","url":null,"abstract":"<div><p>Chiral methyl mandelates are useful synthons in organic transformation and pharmaceutical synthesis. Green synthesis of these valuable compounds by direct C–H activating oxidative hydroxylation has attracted keen interest. Described herein is achieving the stereoselective and efficient bio-hydroxylation of methyl 2-phenylacetates to the chiral methyl mandelates by directed evolution of the cytochrome P450DA hydroxylase. In the present study, a new colorimetric high-throughput screening assay was successfully developed based on a dual-enzyme cascade for the engineering of the P450DA's hydroxylation activity. Several beneficial variants with enhanced bio-hydroxylation activity were created by combining random mutagenesis and site-saturated/directed mutagenesis strategies. Whole-cell bio-hydroxylation of various methyl 2-phenylacetates using the best septuplet-mutant P450DA-11 yielded the corresponding chiral methyl mandelates in up to 92% isolated yields and >99% <em>ee</em>.</p></div>","PeriodicalId":12794,"journal":{"name":"Green Synthesis and Catalysis","volume":"5 2","pages":"Pages 88-93"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666554923000054/pdfft?md5=8b25d52d413e20f9e147427b5b961e35&pid=1-s2.0-S2666554923000054-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87468871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asymmetric reduction of conjugated CC bonds by immobilized fusion of old yellow enzyme and glucose dehydrogenase 通过固定融合老黄酶和葡萄糖脱氢酶不对称还原共轭 CC 键

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2022.10.012

Yongxing Li , Pengqian Luan , Lele Dong , Jianqiao Liu , Luying Jiang , Jing Bai , Fufeng Liu , Yanjun Jiang

{"title":"Asymmetric reduction of conjugated CC bonds by immobilized fusion of old yellow enzyme and glucose dehydrogenase","authors":"Yongxing Li , Pengqian Luan , Lele Dong , Jianqiao Liu , Luying Jiang , Jing Bai , Fufeng Liu , Yanjun Jiang","doi":"10.1016/j.gresc.2022.10.012","DOIUrl":"https://doi.org/10.1016/j.gresc.2022.10.012","url":null,"abstract":"<div><p>Asymmetric reduction of the conjugated C<img>C bonds by the old yellow enzymes (OYEs) presents a promising field in the synthesis of chiral chemicals. Nevertheless, few natural OYEs have been applied in large-scale applications due to the requirement of costly NADPH and low operational stability. Herein, a stable and efficient fusion of YqjM from <em>Bacillus subtilis</em> and glucose dehydrogenase (GDH) from <em>Bacillus megaterium</em> was constructed to stereoselectively reduce the conjugated C<img>C bonds in a self-sufficient continuous process. The effects of the enzyme order and different linkers on the fusions were investigated by structural analysis and all-atom molecular dynamics simulation. The best fusion YqjM_G_GDH gave 98% conversion of 100 mmol/L 2-methylcyclopentenone with an excellent <em>ee</em> value (>99%) in 3 h, while the mixture of individual enzymes only obtained 68% conversion after more than 8 h. The improved substrate conversion of YqjM_G_GDH fusion was probably attributed to the increased flexibility of each fused enzyme and the shortening of the diffusion distance of NADPH regenerated. A one-pot process was designed to purify and immobilize the fusion on the Ni<sup>2+</sup>-nitrilotriacetic acid functionalized magnetic mesoporous silica nanoflowers. The resulting immobilized biocatalyst not only catalyzed the asymmetric reduction of various <em>α,β</em>-unsaturated ketones (20 mmol/L) continuously with only 50 μmol/L NADP<sup>+</sup> to initiate the whole process, but also retained more than 82% of the initial activity after seven cycles, serving as a good candidate for the industrial applications.</p></div>","PeriodicalId":12794,"journal":{"name":"Green Synthesis and Catalysis","volume":"5 2","pages":"Pages 80-87"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666554922001119/pdfft?md5=e72d818078f5545af9df52bf008b7cf4&pid=1-s2.0-S2666554922001119-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Graphene oxide in palladium nanoparticle (GrafeoPlad): a new class of functional materials 钯纳米粒子中的氧化石墨烯（GrafeoPlad）：一类新型功能材料

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2024.04.004

Matteo Formenti, M. Pagliaro, Cristina Della Pina, R. Ciriminna

引用次数: 0

Magnetic wrinkled organosilica-based metal-enzyme integrated catalysts for enhanced chemoenzymatic catalysis 用于增强化学酶催化的磁性皱褶有机硅基金属-酶集成催化剂

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2023.01.008

Yunting Liu , Na Guo , Weixi Kong , Shiqi Gao , Guanhua Liu , Liya Zhou , Jing Gao , Yanjun Jiang

引用次数: 0

Recent advances in transition-metal-free conversion of aldehydes to ketones 无过渡金属醛酮转化的最新进展

Green Synthesis and Catalysis Pub Date : 2024-05-01 DOI: 10.1016/j.gresc.2024.04.007

Yike Bai, Wenhua Yu, Rong Chen, Guipeng Yu, Baosheng Wei

引用次数: 0