Bioceramics Development and Applications最新文献_第3页

Anti-Inflammatory Activity of Quantum Energy Living Body on Lipopolysaccharide-Induced Murine RAW 264.7 Macrophage Cell Line 量子能量活体对脂多糖诱导小鼠RAW 264.7巨噬细胞的抗炎活性

Bioceramics Development and Applications Pub Date : 2016-01-25 DOI: 10.4172/2090-5025.1000089

Jong Doo Lee, E. J. S. Vergara, Soojung Choi, S. Hwang, G. Bahng

{"title":"Anti-Inflammatory Activity of Quantum Energy Living Body on Lipopolysaccharide-Induced Murine RAW 264.7 Macrophage Cell Line","authors":"Jong Doo Lee, E. J. S. Vergara, Soojung Choi, S. Hwang, G. Bahng","doi":"10.4172/2090-5025.1000089","DOIUrl":"https://doi.org/10.4172/2090-5025.1000089","url":null,"abstract":"Recent developments from science and medical science show a growing interest in the anti-inflammatory activity of natural materials. Inflammation is the body’s physiologic response to injurious stimulation and is known to be mediated by various pro-inflammatory cytokines (e.g. TNF-α, IL-1β, IL-6 etc) and iNOS (inducible nitric oxide synthase). Quantum energy living body (QELBY) powder is a fusion of a special ceramic powder with natural clay mineral classified as quantum energy radiating material (QERM). The powder, composed mostly of silicon dioxide, is known to radiate reductive radiant energy. This study was designed to evaluate the anti-inflammatory activities of QELBY powder on RAW 264.7 mouse macrophage cells. QELBY powder was mixed with DMEM media and was allowed to stand for 48 hours. Afterwards, the supernatant was taken and diluted to various concentrations (0,5,10,20,40 μg/ml) prior to use. CCK-8 assay was done to determine the effects on cell viability. In addition, NO assay performed to elucidate the effect of QELBY on the NO production of LPS-stimulated macrophages. Lastly, RT-PCR and Western blot analysis for the detection of the mRNA and protein expressions, respectively, of proinflammatory cytokines and iNOS was made. Results demonstrated that QELBY powder causes both an increase in cell proliferation and a concentration-dependent decrease in NO production. Moreover, the mRNA and protein expressions of pro-inflammatory cytokines and iNOS were also inhibited. Taken together, these show that QELBY powder has anti-inflammatory activity and could therefore be used further in the development of materials that induce such kinds of benefits.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125570165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Zirconia Effect on the Bioactivity and the Mechanical Properties ofCalcium Magnesium Silicate Ceramics at (CaO+MgO)/SiO2 Molar RatioClose to Unity (CaO+MgO)/SiO2摩尔比下氧化锆对硅酸钙镁陶瓷生物活性和力学性能的影响

Bioceramics Development and Applications Pub Date : 2016-01-19 DOI: 10.4172/2090-5025.1000088

A. Amin, E. Ewais, Y. Ahmed, Eman A. Ashor, U. Hess, K. Rezwan

{"title":"Zirconia Effect on the Bioactivity and the Mechanical Properties ofCalcium Magnesium Silicate Ceramics at (CaO+MgO)/SiO2 Molar RatioClose to Unity","authors":"A. Amin, E. Ewais, Y. Ahmed, Eman A. Ashor, U. Hess, K. Rezwan","doi":"10.4172/2090-5025.1000088","DOIUrl":"https://doi.org/10.4172/2090-5025.1000088","url":null,"abstract":"New ceramic composites from calcia-magnesia-silica system at a molar ratio of (CaO-MgO)/SiO2 closes to the unity and the addition of different amounts of zirconia (5 wt %, 15 wt % and 25 wt %) have been investigated. These systems powders were formed and fired at 1310 ± 20°C for 2 hr. Phase composition, microstructure, physical and mechanical properties of these composites were determined. The in-vitro bioactivities of these sintered composites were investigated by analysis of their ability for the formation of hydroxyapatite (HA) using SEM-EDS after their soaking in the simulated body fluid (SBF) for 7 days. The findings indicated that beginning of HA formation on the surface of all investigated composites. However, the composite containing 5 wt % ZrO2 gave clear tendency toward the formation-ability of HA typical to cauliflower morphology. The mechanical properties of the promised bioactive composite in term of Vickers hardness and fracture toughness were ~3 Gpa and ~2 Mpa. m1/2, respectively. The ceramic composite containing 5 wt % ZrO2 might be nominated to be implanted material because their property is quite similar to the properties of human cortical bone.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121408127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Does sandblasting improve bond strength between nano-ceramic resin and two different luting composites? 喷砂是否能提高纳米陶瓷树脂与两种不同的复合材料之间的结合强度?

Bioceramics Development and Applications Pub Date : 2015-11-05 DOI: 10.4172/2090-5025.1000086

A. Davide, Augusti Gabriele, Cerutti Francesca, D. Re

{"title":"Does sandblasting improve bond strength between nano-ceramic resin and two different luting composites?","authors":"A. Davide, Augusti Gabriele, Cerutti Francesca, D. Re","doi":"10.4172/2090-5025.1000086","DOIUrl":"https://doi.org/10.4172/2090-5025.1000086","url":null,"abstract":"Purpose: To assess how sandblasting influences shear bond strength (SBS) between nano-ceramic-resin and two resin cements. Methods: 40 nano-ceramic-resin blocks were divided into two groups (n=20): a control (C) and a test group (S_50) where air abrasion (50 µm, 0.28 MPa,10 s) was applied. Each group was divided into two subgroups (n=10) according to the applied luting material: a self-etch dual-cure resin cement (LP) and a dual-cure resin cement (LR). SBSs were determined with a universal testing machine at a crosshead speed of 0.5 mm/min. Fracture patterns were evaluated by a stereomicroscope (25x) and classified into adhesive, cohesive and mixed. One-way ANOVA test (α=.01) was used to establish differences between groups, considering SBS as dependent and the type of surface treatment as independent variable. Results: Mean SBS (MPa) obtained for P were 8.68 ± 1.16 for C and 13.91 ± 2.58 for S_50. Sandblasting positively affected (p<0.01) the self-adhesive cement adhesion to nano-ceramic resin. Group C_LP showed 100% of adhesive fractures, while S_50_LP had some cohesive (20%) and mixed fractures (10%). The fracture pattern of group C_LR was 60% cohesive, 20% adhesive and 20% mixed, while group S_50-LR showed 100% of cohesive failure. Conclusion: Sandblasting is suggested when luting nano-ceramic resin with LP.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116469056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

A Comparative Study of Static and Kinetic Frictional Resistance during the Sliding of Arch Wires through Orthodontic Brackets, using Different Methods of Ligation, in the Dry State 干状态下不同结扎方式下弓丝在正畸托槽内滑动时静、动摩擦阻力的比较研究

Bioceramics Development and Applications Pub Date : 2015-07-08 DOI: 10.4172/2090-5025.1000085

F. ArmandoMontesinos

引用次数: 1

Self Setting Bone Cement Formulations Based on Egg shell Derived TetraCalcium Phosphate BioCeramics 基于蛋壳衍生磷酸四钙生物陶瓷的自凝骨水泥配方

Bioceramics Development and Applications Pub Date : 2015-04-10 DOI: 10.4172/2090-5025.1000084

Bone cements, Biologically relevant ions

{"title":"Self Setting Bone Cement Formulations Based on Egg shell Derived TetraCalcium Phosphate BioCeramics","authors":"Bone cements, Biologically relevant ions","doi":"10.4172/2090-5025.1000084","DOIUrl":"https://doi.org/10.4172/2090-5025.1000084","url":null,"abstract":"Egg shells have been used as a calcium source for synthesis of tetra calcium phosphate (ETTCP) by solid state reaction method. The cell parameters and cell volume of ETTCP measured by X-ray powder diffraction method were lower than the tetra calcium phosphate prepared using synthetic Ca(CO)3 (pure TTCP) for comparison. The vibration bands of ETTCP were also slightly different from the vibration bands of pure TTCP characterized by Fourier transformed infrared spectroscopy. ETTCP has been tried as a main component in a self setting bone cement to evaluate the advantages of the presence of the biologically relevant ions such as Mg2+, Sr2+, SiO2- 4, F-, K+ and Na+ ions in the cement properties. The setting time of the ETTCP derived cement was ~ 11 min compared to ~ 16 min of the pure TTCP derived cement. The amount of hydroxyapatite formed as the end product was about 12% higher for ETTCP derived cement than pure TTCP derived cement after 28 days of immersion in phosphate buffer solution as confirmed by phase analysis. Elemental analysis also indicates the presence of trace elements in minor concentration in ETTCP derived cement. Although both the cements showed similar compressive strength after 28 days, the initial strength of the ETTCP derived cement was remarkably higher during initial stages of the hardening reaction (24 h–7 days) compared to TTCP derived cement. Cell viability of L6 cells was higher and cell spreading was more for the ETTCP derived cement than pure TTCP derived cement. The present study has demonstrated the advantages of eggshell derived TTCP in bone cement formulations due to the presence of biologically relevant ions. This may help the clinician with brief surgical procedure by using faster setting cement as well as the patient to have quick recovery with a higher initial strength of cement.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117073861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Physical Properties of Calcium Phosphate-Alumina Bio ceramics as DentalImplants 磷酸钙-氧化铝生物陶瓷牙种植体的物理性能研究

Bioceramics Development and Applications Pub Date : 2015-03-22 DOI: 10.4172/2090-5025.1000083

M. HafidMBelafaquir, N. Merzouk, H. AlGana, L. Fajri

引用次数: 3

Novel Bioceramic Scaffolds for Regenerative Medicine 再生医学用新型生物陶瓷支架

Bioceramics Development and Applications Pub Date : 2015-01-25 DOI: 10.4172/2090-5025.1000082

A. Hannickel, Prado da Silva Mh

引用次数: 5

Evaluation of PLAGA/n-HA Composite Scaffold Bioactivity in vitro PLAGA/n-HA复合支架体外生物活性评价

Bioceramics Development and Applications Pub Date : 2014-11-03 DOI: 10.4172/2090-5025.1000080

Q. Lv, Xiaohua Yu, M. Deng, L. Nair, C. Laurencin

{"title":"Evaluation of PLAGA/n-HA Composite Scaffold Bioactivity in vitro","authors":"Q. Lv, Xiaohua Yu, M. Deng, L. Nair, C. Laurencin","doi":"10.4172/2090-5025.1000080","DOIUrl":"https://doi.org/10.4172/2090-5025.1000080","url":null,"abstract":"Polymeric sintered microsphere scaffolds have shown their tremendous potential in bone tissue engineering applications due to their highly porous and interconnected three dimensional structure and excellent mechanical properties. While these scaffolds are able to support basic cellular activity after seeding cells on them, the bioactivity of these scaffolds in terms of enhancing the biological performance of stem cells during bone regeneration is still under satisfactory. We hypothesized that incorporation of bioactive addictive such as hydroxyapatite into these scaffolds could improve their bioactivity without sacrificing the bulk properties of the scaffolds. We have successfully incorporated nano-hydroxyapatite (n-HA) into poly (lactic acid-glycolic acid) (PLAGA) microsphere based scaffolds in our previous studies. Herein, we aimed to evaluate the bioactivity of PLAGA/n-HA composite scaffolds, with a focus on studying the mineralization of the scaffolds in vitro. The capability of inducing apatite formation in vitro was largely enhanced in the composite scaffolds compared to plain PLAGA scaffolds. More importantly, PLAGA/n-HA composite scaffolds have been shown to improve rabbit mesenchymal stem cells (RMSCs) proliferation, differentiation, and mineralization as compared to control PLAGA scaffolds. Taken together, introduction of n-HA appears to be an efficient approach to improve the bioactivity of PLAGA scaffolds for bone tissue engineering.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129224303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Silver and Gadolinium Ions Co-substituted Hydroxyapatite Nanoparticles as Bimodal Contrast Agent for Medical Imaging 银和钆离子共取代羟基磷灰石纳米颗粒作为医学成像的双峰造影剂

Bioceramics Development and Applications Pub Date : 2014-10-31 DOI: 10.4172/2090-5025.1000079

K. Madhumathi, S. Ts, T. MohammedSanjeed, A. SabikMuhammed, Sahal Nazrudeen, D. Sharanya

{"title":"Silver and Gadolinium Ions Co-substituted Hydroxyapatite Nanoparticles as Bimodal Contrast Agent for Medical Imaging","authors":"K. Madhumathi, S. Ts, T. MohammedSanjeed, A. SabikMuhammed, Sahal Nazrudeen, D. Sharanya","doi":"10.4172/2090-5025.1000079","DOIUrl":"https://doi.org/10.4172/2090-5025.1000079","url":null,"abstract":"Developing multimodal contrast agents is an upcoming area and hydroxyapatite nanoparticles substituted with various elements like gadolinium, eurobium etc., seems to be a promising contrast agent, especially for multimodal imaging of bone-tissue interface. A bimodal contrast agent using silver (Ag+) and gadolinium (Gd3+) ions co-substituted hydroxyapatite nanoparticles has been developed for X-ray and magnetic resonance imaging. Ag+ and Gd3+ ions were co-substituted into hydroxyapatite at various atomic percentages (Ag:Gd=0.25:0.25, 0.25:0.5, 0.25:0.75) using microwave accelerated wet chemical synthesis. Pure as well as Ag+ and Gd3+ ions substituted hydroxyapatite samples were also synthesized for comparison. All samples were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy etc., and found to be monophasic, nanocrystalline with the substituted ions. These co-substituted hydroxyapatite samples were then tested in different diagnostic modalities such as X-ray, computed tomography imaging and magnetic resonance imaging. Appreciable variation in contrast was observed with different amount of substitutions. All the Ag+ and Gd3+ ions co-substituted hydroxyapatite nanoparticles showed higher contrast in all imaging modalities compared to those substituted with either Ag+ or Gd3+ ions only. Hydroxyapatite sample co-substituted with 0.25Ag and 0.75Gd at. % substitution showed the best bimodal CT-MRI contrast.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131092123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Calcium Orthophosphates: Occurrence, Properties and Major Applications 正磷酸钙:发生、性质及主要应用

Bioceramics Development and Applications Pub Date : 2014-10-27 DOI: 10.4172/2090-5025.1000081

S. Dorozhkin

引用次数: 14