发布求助
文献互助 智能选刊 最新文献

Bioceramics Development and Applications最新文献

筛选
英文 中文
Effect of Test Circumstances on Compressive Strength of Porous Calcium Phosphate Ceramics for Establishment of Standard Measurement Condition 试验环境对多孔磷酸钙陶瓷抗压强度的影响——建立标准测量条件
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101201
M. Kikuchi
{"title":"Effect of Test Circumstances on Compressive Strength of Porous Calcium Phosphate Ceramics for Establishment of Standard Measurement Condition","authors":"M. Kikuchi","doi":"10.4303/BDA/D101201","DOIUrl":"https://doi.org/10.4303/BDA/D101201","url":null,"abstract":"In order to establish a reasonable biomimetic condition for compressive strength of bioactive ceramics, the compressive strengths of several commercial bioactive ceramics were measured under various conditions. All specimens except for one of Japanese ceramics, specimen A, showed no significant differences among the conditions, but showed a tendency of decreasing the compressive strength more than 10% in comparison to the dry condition that was conventionally described in product brochures. Further, the specimen A indicated a significant decrease of the compressive strength in 24 h soaking conditions. Accordingly, a recommended biomimetic condition would be that specimen would be soaked in PBS after deaeration at 25 °C for 24 h and measured in air after brief wiping surface liquid.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134552107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Biomimetic Calcium Phosphate Coatings for Polymeric Artificial Spinal Disc Implants 高分子人工椎间盘植入物的仿生磷酸钙涂层
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101111
Dunstan H Barnes, R. Cameron, S. Kiamil, F. Meyer, R. Brooks, N. Rushton, S. Best
{"title":"Biomimetic Calcium Phosphate Coatings for Polymeric Artificial Spinal Disc Implants","authors":"Dunstan H Barnes, R. Cameron, S. Kiamil, F. Meyer, R. Brooks, N. Rushton, S. Best","doi":"10.4303/BDA/D101111","DOIUrl":"https://doi.org/10.4303/BDA/D101111","url":null,"abstract":"Discs of poly carbonate urethane (PCU) were coated with a thin layer of calcium phosphate (CaP) by a biomimetic process at temperatures of 28?C and 37?C. The coating morphology was analyzed by SEM. Contact angle analysis was used to assess surface wettability. Human osteoblasts (HOBs) were cultured on uncoated and CaP-coated PCU discs for up to 14 days. Cell metabolism, structure, and morphology were analyzed and compared with the wettability of each sample group. HOBs proliferated and grew on uncoated and CaP-coated samples, but a greater cell metabolism was observed for uncoated samples at early time points in cell culture. A more even dispersion of HOBs across the disc surface, attributable to the increased surface wettability, was seen for CaP-coated samples.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134239463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Bioactivity and Osteoconductivity of Biphasic Calcium Phosphates 双相磷酸钙的生物活性和骨导电性
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101129
Jung Sang Cho, C. Chung, S. Rhee
{"title":"Bioactivity and Osteoconductivity of Biphasic Calcium Phosphates","authors":"Jung Sang Cho, C. Chung, S. Rhee","doi":"10.4303/BDA/D101129","DOIUrl":"https://doi.org/10.4303/BDA/D101129","url":null,"abstract":"Bioactivity and osteoconductivity of calcium phosphates as a function of ?-tricalcium phosphate contents, that is, biodegradability, were investigated. Three calcium phosphates, pure hydroxyapatite, biphasic calcium phosphates with different mixing ratios between hydroxyapatite, and ?-tricalcium phosphate (60HAp:40?- TCP and 40HAp:60?-TCP in wt.%), were synthesized through the precipitation method using calcium hydroxide and phosphoric acid as starting reactants. After drying, they were sintered at 1100 °C for 3 hours, and then bioactivity and osteoconductivity tests were carried out in simulated body fluid (SBF) and calvarial defect of New Zealand white rabbits, respectively. SBF exposure resulted in the deposition of a layer of carbonate apatite crystals on the surfaces of bicalcium phosphates but not on the hydroxyapatite. New bone forming capacity of the biphasic calcium phosphate with 60HAp:40?-TCP granules was the best, whereas that of the pure HAp was the worst. To this end, it can be concluded that the calcium phosphate with moderate biodegradability is good for producing good osteoconductivity.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114044503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
A Processing Approach to Tuning the Drug Delivery Characteristics of Calcium Polyphosphate Matrices 调整聚磷酸钙基质给药特性的加工方法
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101101
M. Filiaggi, N. Djogbenou, G. Hall
{"title":"A Processing Approach to Tuning the Drug Delivery Characteristics of Calcium Polyphosphate Matrices","authors":"M. Filiaggi, N. Djogbenou, G. Hall","doi":"10.4303/BDA/D101101","DOIUrl":"https://doi.org/10.4303/BDA/D101101","url":null,"abstract":"Amorphous calcium polyphosphate (CPP) has potential as an implantable drug delivery matrix by virtue of a low temperature gelling protocol that has been shown to eliminate burst release and extend drug release time from the matrix. However, a greater understanding of this material’s interaction with aqueous environments is needed to more fully exploit this application. Variations in aqueous exposure were assessed using as-made amorphous CPP as well as CPP processed using established low temperature protocols. Solid-state 31P-NMR along with thermal and X-ray diffraction analyses were used to track resulting structural changes. Exposure to aqueous environments caused a reduction in CPP chain length that was dependant on gel time and mode of exposure. Significantly, increased gel times or water availability further resulted in crystallization events upon drying, except in the presence of a buffered solution. In general, drug elution studies showed an increase in the burst release of vancomycin from CPP disks gelled for extended periods, with matrix-water interactions appearing to be most influential during the drug loading stage. Overall, this study shows that CPP drug delivery matrices can be produced with tailored properties by closely controlling CPP-water interactions during processing.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123686729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Difference in Osteoclast Responses to Tricalcium Phosphate in Culture Medium Supplemented with Zinc and to Zinc-Containing Tricalcium Phosphate 加锌培养基中破骨细胞对磷酸三钙和含锌培养基中破骨细胞对磷酸三钙反应的差异
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101106
Xia Li, Koji Senda, A. Ito, Y. Sogo, and Atsushi Yamazaki
{"title":"Difference in Osteoclast Responses to Tricalcium Phosphate in Culture Medium Supplemented with Zinc and to Zinc-Containing Tricalcium Phosphate","authors":"Xia Li, Koji Senda, A. Ito, Y. Sogo, and Atsushi Yamazaki","doi":"10.4303/BDA/D101106","DOIUrl":"https://doi.org/10.4303/BDA/D101106","url":null,"abstract":"Difference in osteoclast responses (i.e., apoptosis, actin ring formation) to tricalcium phosphate (TCP) in culture medium supplemented with zinc and to zinc-containing tricalcium phosphate (ZnTCP) was investigated in this study. On the TCP ceramic, an increase in zinc ion in the culture medium within the range between 0.3 and 6.8 ppm significantly induced an increase in osteoclast apoptosis and a decrease in actin ring formation. However, even a high level of magnesium ion up to 100 ppm in the culture medium or up to 6.8mol% in the ceramic was unlikely to influence osteoclast activity. There was almost no significant difference in osteoclast apoptosis and actin ring formation between ZnTCP with 1mol% zinc and magnesiumcontaining tricalcium phosphate with 1.5mol% magnesium ceramic which have the same solubility and the same dissolution rate. It is suggested that only an increase in zinc level outside resorption lacuna has an inhibitory effect on osteoclast resorption and that an increase in zinc level inside resorption lacuna could not influence osteoclast activity.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127190564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Novel Patterning of Silicon-Substituted Hydroxyapatite 硅取代羟基磷灰石的新图型
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101109
G. Munir, Xiang Li, M. Edirisinghe, W. Bonfield, M. Esat, J. Huang
{"title":"Novel Patterning of Silicon-Substituted Hydroxyapatite","authors":"G. Munir, Xiang Li, M. Edirisinghe, W. Bonfield, M. Esat, J. Huang","doi":"10.4303/BDA/D101109","DOIUrl":"https://doi.org/10.4303/BDA/D101109","url":null,"abstract":"Template-assisted electrohydrodynamic atomisation (TAEA) spraying of nanometer-sized siliconsubstituted hydroxyapatite (nanoSiHA) was used to pattern implant surfaces for guided cell growth to improve the repair and regeneration of medical implants. A suspension of nanoSiHA was prepared and characterized. Patterns of pillars and tracks of various dimensions were prepared using the suspension. It was found that the resolution of the pattern was affected by TAEA processing parameters, such as applied voltage, flow rate, distance between needle and substrate, and spray time. Fifteen minutes spraying time provided the most clear and uniform patterned topography with a distance between nozzle and substrate of 50mm and a flow rate of 4?l/min. Therefore, well-defined nanoSiHA patterns can be achieved by TAEA deposition, it thus offers great potential for patterning the surface of medical implants.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115702786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Electrospun Titania Oxide Nanofibers Coupled Zinc Oxide Nanobranches as a Novel Nanostructure for Lithium Ion Batteries Applications 电纺丝氧化钛纳米纤维耦合氧化锌纳米分支作为锂离子电池的新型纳米结构
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D110129
Muzafar A. Kanjwal, N. Barakat, F. A. Sheikh, H. Kim
{"title":"Electrospun Titania Oxide Nanofibers Coupled Zinc Oxide Nanobranches as a Novel Nanostructure for Lithium Ion Batteries Applications","authors":"Muzafar A. Kanjwal, N. Barakat, F. A. Sheikh, H. Kim","doi":"10.4303/BDA/D110129","DOIUrl":"https://doi.org/10.4303/BDA/D110129","url":null,"abstract":"First, electrospinning of colloidal solution consisting of titanium isopropoxide/poly(vinyl acetate) zinc nanoparticles has been achieved to produce polymeric nanofibers embedding solid nanoparticles. Calcination of the obtained electrospun nanofiber mats in air at 600 °C has been revealed to produce TiO2 nanofibers containing ZnO nanoparticles; ZnO-doped TiO2 nanofibers. The formed ZnO nanoparticles have been exploited as seeds to outgrow ZnO branches around the TiO2 nanofibers using a hydrothermal technique. As anode in lithium ion battery, the prepared nanostructure exhibited a high rate capacity of 1232 mAhg–1.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128342541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Calcium Phosphate Formation on Titanium and Zirconium and Its Application to Medical Devices 钛和锆上形成磷酸钙及其在医疗器械中的应用
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D110119
T. Hanawa, Y. Tsutsumi
{"title":"Calcium Phosphate Formation on Titanium and Zirconium and Its Application to Medical Devices","authors":"T. Hanawa, Y. Tsutsumi","doi":"10.4303/BDA/D110119","DOIUrl":"https://doi.org/10.4303/BDA/D110119","url":null,"abstract":"Titanium and zirconium were immersed in Hanks’ solution with and without calcium and phosphate ions, and the surfaces were characterized with X-ray photoelectron spectroscopy (XPS) to determine the mechanism of calcium phosphate formation on titanium in simulated body fluids and in a living body. In addition, they were cathodically polarized in the above solutions. As a result, neither calcium nor phosphate stably exists alone on titanium, and calcium phosphate is naturally formed on it; calcium phosphate formed on titanium is stable and protective. On the other hand, calcium is never incorporated on zirconium, while zirconium phosphate, which is easily formed on zirconium, is highly stable and protective.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124630087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Application of Imogolite, Almino-Silicate Nanotube, as Scaffold for the Mineralization of Osteoblasts 硅酸铝纳米管在成骨细胞矿化支架中的应用
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D110133
K. Ishikawa, T. Akasaka, S. Abe, Y. Yawaka, Masaya Suzuki, F. Watari
{"title":"Application of Imogolite, Almino-Silicate Nanotube, as Scaffold for the Mineralization of Osteoblasts","authors":"K. Ishikawa, T. Akasaka, S. Abe, Y. Yawaka, Masaya Suzuki, F. Watari","doi":"10.4303/BDA/D110133","DOIUrl":"https://doi.org/10.4303/BDA/D110133","url":null,"abstract":"Imogolite is a naturally occurring aluminosilicate clay mineral with a nanotube structure. In this study, synthetic imogolite nanotubes were applied to cell culture and the properties as scaffold were compared with those of a conventional culture dish and the carbon nanotube scaffold. The surface characteristics of the imogolite scaffold were drastically changed with the amount of imogolite on the dish. Human osteoblast-like cells (SaOS2) on imogolite scaffolds showed a widely spreading morphology and a high functional expression. Particularly, the scaffold with the large amount of imogolite provided the suitable environments of topography, roughness, wettability and protein adsorption ability for widely spreading morphology and differentiation of osteoblasts. Imogolite retains various positive factors as scaffolds for osteoblastic proliferation and differentiation and is expected for the application to bone tissue engineering.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125166148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
BSA Attachment on Apatite Surface Modified with Zn2+ and Sr2+ Zn2+和Sr2+改性磷灰石表面BSA的附着
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101115
E. Mavropoulos, M.L.F.M. Kede, N. D. C. Rocha, A. M. Costa, A. Tosi, M. H. P. D. Silva, A. Rossi
{"title":"BSA Attachment on Apatite Surface Modified with Zn2+ and Sr2+","authors":"E. Mavropoulos, M.L.F.M. Kede, N. D. C. Rocha, A. M. Costa, A. Tosi, M. H. P. D. Silva, A. Rossi","doi":"10.4303/BDA/D101115","DOIUrl":"https://doi.org/10.4303/BDA/D101115","url":null,"abstract":"Synthetic hydroxyapatite was modified with zinc and strontium by two methods: ion exchange and coprecipitation synthesis. Hydroxyapatite and metal modified hydroxyapatite samples were characterized by XRD, ICP-OES, and FTIR-DRS. BSA adsorption experiments were accomplished during 24 hours using 1.0mg/mL of protein. UV spectrometry was used to quantify the protein at 278 nm. The results suggest that metal presence on the surface or in the bulk of hydroxyapatite improves the protein adsorption efficiency. FTIR-DRS showed that the protein main secondary structure ?-Helix is involved in the adsorption process.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127382535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信