发布求助
文献互助 智能选刊 最新文献

Bioceramics Development and Applications最新文献

筛选
英文 中文
Biological Effect of Calcium Phosphate Bioceramics Microstructure 磷酸钙生物陶瓷微结构的生物效应
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101113
Serge Baroth, G. Daculsi
{"title":"Biological Effect of Calcium Phosphate Bioceramics Microstructure","authors":"Serge Baroth, G. Daculsi","doi":"10.4303/BDA/D101113","DOIUrl":"https://doi.org/10.4303/BDA/D101113","url":null,"abstract":"Understanding of interactions between cells and biomaterials is a huge parameter for improving tissue engineering and regenerative medical fields. Many different materials have already been tested (including calcium phosphate ceramics) and it has been established that surface characteristic is a parameter that influences cell responses. The aim of this work was to characterize calcium phosphate discs containing various ratios of HA/?-TCP and specific microstructure. First results show that chemical composition and compression parameters modify surface materials. Secondly, cells were cultured (osteoblast-like cells MC3T3- E1) and morphology, viability, and differentiation were studied. SEM observations, mitochondrial (MTS assay), and alkaline phosphatase activity (ALP) measurements showed that osteoblasts have better viability and a higher rate of differentiation when cultured on dense surface compared to porous surface. The aim of this experiment was to contribute to the knowledge of interactions between osteoblast-like cells and microstructured calcium phosphate bioceramics pellets.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121270458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Forming Fibrous Nanocomposite Tissue Engineering Scaffolds Through Electrospinning: a Comparative Study of Three Fabrication Routes 静电纺丝制备纤维纳米复合材料组织工程支架:三种制备工艺的比较研究
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D110107
H. Tong, Min Wang
{"title":"Forming Fibrous Nanocomposite Tissue Engineering Scaffolds Through Electrospinning: a Comparative Study of Three Fabrication Routes","authors":"H. Tong, Min Wang","doi":"10.4303/BDA/D110107","DOIUrl":"https://doi.org/10.4303/BDA/D110107","url":null,"abstract":"Due to osteoconductivity of hydroxyapatite (HA), HA/polymer composite scaffolds have been investigated for bone tissue engineering by various groups. In scaffold fabrication, electrospinning of ultrafine fibrous scaffolds incorporated with substantial amounts of evenly distributed HA nanoparticles is still a challenge. The problem of nanoparticle agglomeration not only reduces the electrospinning efficiency but also undermines the homogeneity of the distribution of the HA nanoparticles along the fibers. In this study, an approach using ultrasonification was developed so as to electrospin fibrous nanocomposite scaffolds having the carbonated HA (CHA) nanosphere content up to about 15 wt% with minimal agglomeration of CHA nanospheres. SEM and EDX results showed an even distribution of CHA nanospheres while FTIR results further confirmed the presence of CHA within the electrospun fibers. The nanocomposite fibrous scaffolds fabricated through this route could be used in further investigations for bone tissue engineering applications.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125741080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Development of Osseointegrative Ceramic Coatings Based onZPTAâMechanical Characterization and Influence on the Substrate 基于zpta<e:1>的骨整合陶瓷涂层的研制及其对基体的影响
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101202
B. Theelke, M. Kuntz, M. Zipperle, S. Eichhorn, T. Boxleitner, Orf, R. Burgkart
{"title":"Development of Osseointegrative Ceramic Coatings Based onZPTAâMechanical Characterization and Influence on the Substrate","authors":"B. Theelke, M. Kuntz, M. Zipperle, S. Eichhorn, T. Boxleitner, Orf, R. Burgkart","doi":"10.4303/BDA/D101202","DOIUrl":"https://doi.org/10.4303/BDA/D101202","url":null,"abstract":"In this article, the mechanical characterization of a monolithic cup made of BIOLOX\u0002delta with a porous ceramic coating for osseointegration is presented. During the coating process, a ceramic slurry is deposited on a green substrate, both slurry and substrate are based on BIOLOX\u0002delta. To achieve a porous coating, organic pore-forming agents were used which are pyrolized in the following sintering process. Porosities of 18 to 47% could be reached depending on the layer thickness. Extensive mechanical investigations were applied on the fabricated cups to verify the suitability of the produced porous layers for biomechanical demands of the interface between bone and dense substrate. The test results showed that coated ceramic cups require comparable push out forces for the disconnection from artificial bone to established metal shells with plasma sprayed titanium coatings.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132942554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Next Generation Antibacterial Hydroxyapatite Coating: Antibacterial Activity of Ag Ions in Serum 新一代抗菌羟基磷灰石涂层:血清中Ag离子的抗菌活性
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101102
I. Noda, F. Miyaji, Y. Ando, H. Miyamoto, T. Shimazaki, Y. Yonekura, M. Miyazaki, M. Mawatari, T. Hotokebuchi
{"title":"Next Generation Antibacterial Hydroxyapatite Coating: Antibacterial Activity of Ag Ions in Serum","authors":"I. Noda, F. Miyaji, Y. Ando, H. Miyamoto, T. Shimazaki, Y. Yonekura, M. Miyazaki, M. Mawatari, T. Hotokebuchi","doi":"10.4303/BDA/D101102","DOIUrl":"https://doi.org/10.4303/BDA/D101102","url":null,"abstract":"We developed a novel thermal spraying technology for a silver-containing hydroxyapatite (Ag-HA) coating with antibacterial activity to reduce the incidence of implant-associated infections. In this study, we determined the concentration of Ag ions that show antibacterial activity in fetal bovine serum (FBS) and antibacterial activity of the Ag-HA coating in FBS. The minimum inhibitory concentration (MIC) of Ag ions for several bacteria in FBS was in the range of 4.0–7.9 ppm. When 10 ppm Ag were added (as AgNO3 solution), 0.01 ppm of free Ag ions was detected. As the MIC of Ag ions approached the concentration that enabled formation of free Ag ions in FBS, the antibacterial activity of added Ag can be attributed to the free Ag ions. The Ag-HA coating showed strong antibacterial activity in FBS as well; the Ag concentration in FBS was 26 ppm for the antibacterial test of the Ag-HA coating. Because the Ag-HA coating can release sufficient free Ag ions in FBS, we observed that the Ag-HA coating shows a strong antibacterial effect in the biological medium studied.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124983299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Fabrication of Apatite-Hyaluronic Acid Hybrids 磷灰石-透明质酸杂合体的制备
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D110117
S. Nagashima, Y. Morita, T. Miyazaki, E. Ishida, K. Tanaka, T. Goto
{"title":"Fabrication of Apatite-Hyaluronic Acid Hybrids","authors":"S. Nagashima, Y. Morita, T. Miyazaki, E. Ishida, K. Tanaka, T. Goto","doi":"10.4303/BDA/D110117","DOIUrl":"https://doi.org/10.4303/BDA/D110117","url":null,"abstract":"Apatite-polymer hybrids have been attractive as novel bone-bonding bioactive bone substitutes with mechanical performances analogous to those of natural bone. It is shown that carboxyl group (COOH) can induce the apatite nucleation in an environment of simulated body fluid (SBF). In the present study, we fabricated porous hyaluronic acid gels abundant in COOH group and investigated their apatite formation ability in SBF. Hyaluronic acid has been attractive for boneand cartilagerepairing materials due to high biological compatibility. We attempted the preparation of bioactive organic-inorganic hybrids from Hyaluronic acid. It has been attractive for boneand cartilage-repairing materials due to high biological compatibility. It is known that divinyl sulfone is a candidate of cross-linker to bridge the hydroxyl groups. The hydroxyl group of hyaluronic acid side chains were bridged by divinyl sulfone. Porous hyaluronic acid gels stable in aqueous environment were obtained by appropriate crosslinking. They formed the apatite on their surfaces in SBF, when they were priorly treated with CaCl2 aqueous solution. In addition, trehalose, a kind of disaccharide, is found to increase the pore size of the porous hyaluronic acid. This suggests that the pore size and porosity can be controlled by addition of trehalose during fabrication of the scaffolds.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114166101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Characteristics of Silver-Hydroxyapatite/PVP Nanocomposite 银-羟基磷灰石/PVP纳米复合材料的性能研究
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101128
A. Mostafa, H. Oudadesse, E. Foad, G. Cathelineau
{"title":"Characteristics of Silver-Hydroxyapatite/PVP Nanocomposite","authors":"A. Mostafa, H. Oudadesse, E. Foad, G. Cathelineau","doi":"10.4303/BDA/D101128","DOIUrl":"https://doi.org/10.4303/BDA/D101128","url":null,"abstract":"Metal nanoparticles play an important role in many different areas such as catalysis, electronics, sensors, and cancer therapy. Silver, in its many oxidation states (Ag0, Ag+, Ag2+, and Ag3+), has long been recognized as having an inhibitory effect towards many bacterial strains and microorganisms commonly present in medical and industrial processes. Silver was introduced in various materials including hydroxyapatite due to its biocompatibility. The unique size-dependent properties of nanomaterials make them superior and indispensable. In this work, nanohydroxyapatite/polyvinylpyrrolidone composite was doped with 2 different concentrations of silver nanoparticles prepared by reduction method. Several techniques like TEM, XRD, FT-IR, and SEM with EDS were used to characterize the prepared samples. The bioactivity test (soaking in SBF) at different short time intervals was characterized by using inductively coupled plasma-optical emission spectroscopy (ICP-OES) method. It is demonstrated that silver-doped nanohydroxyapatite obviously improves the bioactivity of the apatite at the early stages of immersion. The antibacterial inhibition over 3 types of bacteria (Staphylococcus aureus, Streptococcus mutans, and Pseudomonas) is under investigation.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123964912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Hydroxyapatite Particulate Nanofiber Modified Titanium: In-Vitro Bioactivity 羟基磷灰石颗粒纳米纤维改性钛:体外生物活性
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D110131
M. P. Bajgai, D. Parajuli, S. Park, K. Chu, Hyung-Sub Kang, H. Kim
{"title":"Hydroxyapatite Particulate Nanofiber Modified Titanium: In-Vitro Bioactivity","authors":"M. P. Bajgai, D. Parajuli, S. Park, K. Chu, Hyung-Sub Kang, H. Kim","doi":"10.4303/BDA/D110131","DOIUrl":"https://doi.org/10.4303/BDA/D110131","url":null,"abstract":"Current work demonstrates the ability of titanium based implant surfaces to promote human osteoblasts (HOBs) differentiation and matrix production, and enhance osseointegration in vitro. Titanium surface was modified by electrospinning with sol-gel-derived hydroxyapatite (HAp) and successively calcined at various temperatures. After heat-treatment, the crystal structure of the filmed titanium oxide and sol-gel-derived crystalline HAp on titanium’s surface was identified using wide-angle X-ray diffraction. Surfaces of three different samples, HAp electrospun and calcined at 600, 700 and 800 °C, were investigated in terms of their ability of promotion, adherence, proliferation and differentiation of human HOB cells in vitro up to 6 days. The cells cultured on electrospun and 800 °C calcined titanium surfaces showed the best results among three samples in terms of adhesion, growth and proliferation of HOBs. This work would provide a promising alternative for titaniumbased medical devices since it provides enhancement both on the surface and bulk properties.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124791628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effect of Particle Size of Magnetite Nanoparticles on Heat Generating Ability under Alternating Magnetic Field 磁铁矿纳米颗粒粒径对交变磁场下发热能力的影响
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D110128
Z. Li, M. Kawashita, N. Araki, M. Mistumori, M. Hiraoka
{"title":"Effect of Particle Size of Magnetite Nanoparticles on Heat Generating Ability under Alternating Magnetic Field","authors":"Z. Li, M. Kawashita, N. Araki, M. Mistumori, M. Hiraoka","doi":"10.4303/BDA/D110128","DOIUrl":"https://doi.org/10.4303/BDA/D110128","url":null,"abstract":"In this study, magnetite nanoparticles (MNPs) with series of size varying from 8 nm to 103 nm were synthesized by a chemical co-precipitation and an oxidationprecipitation method to aim for finding the optimum particle size which has high heating efficiency in the applied magnetic field (9.6–23.9 kA·m–1, 100 kHz). Their in vitro heating efficiencies in agar phantom, at a MNPs concentration of 58 mg Fe·ml–1, were measured in the applied field. The temperature increase (ΔT) of the agar phantom at 30 s was 9.3 °C for MNPs of 8 nm, exhibiting a high heating efficiency in a field intensity of 9.6 kA·m–1. The ΔT of agar was 55 °C for MNPs of 24 nm and 25 °C for MNPs of 8 nm in a field intensity of 23.9 kA·m–1. The excellent heating efficiency for MNPs of 24 nm might be a combined effect of relaxation loss and hysteresis loss of the magnetic particles.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123656642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
The Effect of Adding Chondroadherin to an Injectable Ceramic Bone Substitute on Bone Ingrowth 可注射陶瓷骨替代物中添加软骨粘附素对骨长入的影响
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D101105
H. E. Ozturk, J. Wang, L. Lidgren, D. Heinegård
{"title":"The Effect of Adding Chondroadherin to an Injectable Ceramic Bone Substitute on Bone Ingrowth","authors":"H. E. Ozturk, J. Wang, L. Lidgren, D. Heinegård","doi":"10.4303/BDA/D101105","DOIUrl":"https://doi.org/10.4303/BDA/D101105","url":null,"abstract":"Objective. The aim of the present study is to prepare a 3D porous silk fibroin scaffold with a hierachical structure that can meet the demands for bone tissue engineering. Materials and Methods. 3D fibroin scaffold was prepared by the methods of partial dissolution in acid solution and freeze drying fibroin solution. Results. The nets were composed of a mesh of randomly oriented fibers that ranged between 10 ?m and 30 ?m in diameter. Branchpoints and three dimensional open spaces were distributed throughout the structure with an average pore size of about 177.9 ± 40.0 ?m. Conclusion. With the methods of non-woven silk fibroin net preparation and frozen-dried technics, it is possible to prepare a 3D porous silk fibroin scaffold with hierachical fine structure.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129036644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomolecules Loading and Mesoporous SBA-15 Pore Sizes 生物分子负载和介孔SBA-15孔径
Bioceramics Development and Applications Pub Date : 2010-12-02 DOI: 10.4303/BDA/D110126
Y. Yokogawa, T. Toma, A. Saito, A. Nakamura, I. Kishida
{"title":"Biomolecules Loading and Mesoporous SBA-15 Pore Sizes","authors":"Y. Yokogawa, T. Toma, A. Saito, A. Nakamura, I. Kishida","doi":"10.4303/BDA/D110126","DOIUrl":"https://doi.org/10.4303/BDA/D110126","url":null,"abstract":"The encapsulation and immobilization of biomolecules on solid materials, mesoporous SBA-15, have been studied. Highly ordered hexagonal mesoporous silicates (MPS) with different mean pore sizes have been synthesized using two kinds of triblock copolymers (P123 or L123) as a template. The mixture of tetraethyl orthosilicate (TEOS) and the triblock copolymer (poly(ethylene glycol)poly(propylene glycol)-poly(ethylene glycol)) was stirred and hydrothermally treated at various temperatures to form the MPS structure. Higher temperatures during stirring and hydtrothermal treatment led to the enlargement of pore size. UV-spectrometry was performed to determine the amount of bovine serum albumin (BSA) encapsulated in MPS. It was found that the adsorption processes of BSA on/in MPS could be well described by intraparticle diffusion model.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126235077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信