{"title":"Intimate partner violence and health among Mexican women with and without disabilities: a population-based study, 2021.","authors":"Liliana Giraldo-Rodríguez, Marcela Agudelo-Botero","doi":"10.24875/GMM.M26001112","DOIUrl":"https://doi.org/10.24875/GMM.M26001112","url":null,"abstract":"<p><strong>Background: </strong>Intimate partner violence (IPV) is a serious public health issue affecting millions of women, with more severe consequences among those with disabilities.</p><p><strong>Objective: </strong>To estimate the prevalence of IPV and disability, disaggregated by type and cause of violence, and to analyze the physical and mental health problems associated with IPV among Mexican women with and without disabilities.</p><p><strong>Material and methods: </strong>This cross-sectional study was based on the 2021 National Sur-vey on the Dynamics of Household Relationships. Data from 47,312,856 women aged 15 years and older with at least one lifetime intimate relationship were analyzed. Prevalence estimates and adjusted risk ratios were calculated.</p><p><strong>Results: </strong>Women with disabilities showed a higher lifetime prevalence of IPV (44.8% vs. 37.8%) and past-year prevalence (22.6% vs. 20.5%) compared to women without disabilities. Sexual violence was associated with the highest risk (relative risk: 2.09). This group also reported more frequent physical (e.g., fractures, sexually transmitted infections) and psychological consequences (e.g., depression 63.8%, suicidal ideation 23.9%).</p><p><strong>Conclusions: </strong>Disability increased the vulnerability of women experiencing IPV and worsened its health consequences. There is an urgent need for integrated interventions that address health, disability, and gender-based violence.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"117-125"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The other side of the coin: health-related applications of some metabolites produced by Pseudomonas aeruginosa.","authors":"Gloria Soberón-Chávez","doi":"10.24875/GMM.M26001106","DOIUrl":"https://doi.org/10.24875/GMM.M26001106","url":null,"abstract":"<p><p>Pseudomonas aeruginosa is an opportunistic pathogen with high intrinsic and acquired antibiotic resistant levels, so the World Health Organization has defined this bacterium as a priority pathogen for research. In the case of Mexico, different strains belonging to a sequence-type (ST309) that is considered as high-risk due to its wide geographical distribution in different countries, and its high levels of antimicrobial resistance have been isolated, so the research with this bacterium is an active field. In a contrasting way, it has been recognized for decades, that some metabolites produce by this bacterium, like rhamnolipids and pyocyanin, have important biotechnological applications. In this review, some uses of these metabolites in health-related applications are presented, as well as some strategies that have been followed to produce them at an industrial scale, despite P. aeruginosa virulence.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"52-60"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guadalupe M L Guerrero-Avendaño, Ana L Sánchez-Sandoval, Eira V Barrón-Palma
{"title":"Research gap and its impact on women's health.","authors":"Guadalupe M L Guerrero-Avendaño, Ana L Sánchez-Sandoval, Eira V Barrón-Palma","doi":"10.24875/GMM.M26001105","DOIUrl":"https://doi.org/10.24875/GMM.M26001105","url":null,"abstract":"<p><p>Currently, we are in a global context where women's human rights, particularly equality and autonomy, have gained increasing relevance. At the same time, national and international documents have been updated, and knowledge about violence against women has expanded, recognizing its various forms (physical, psychological, and sexual) as well as its different settings (family, community, workplace, and healthcare). This highlights that many aspects of women's health are deeply linked to inequality and violence. Investment in biomedical research has a direct impact on population health. If there were no lag in research on women's health, this should also be reflected in women's life expectancy. However, it is essential to prioritize the concept of \"healthy life expectancy\" in order to reach more accurate conclusions. To answer the questions of whether there is a lag in research on women's health and how this lag affects their well-being we propose addressing three key areas: quality-adjusted life expectancy, the evaluation of research projects that include and analyze data by sex, and equitable participation of women in science. Finally, understanding the current landscape of research by and for women in health is essential for designing strategies that help eliminate inequality and violence against women.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"45-51"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lourdes Basurto, Violeta Castro-Leyva, Sara Vega-García, Laura L Lugo-Salcedo, Leticia Manuel-Apolinar, Jennyfer M Gaspar-Gurza, Paola Sánchez-Ramos, Ivon K Ruiz-López, Rosalinda Sánchez-Arenas, Sandra Jarquín-López, Nilson A Contreras-Carreto
{"title":"High levels of MCP-1 in menopause and their relationship with components of the metabolic syndrome.","authors":"Lourdes Basurto, Violeta Castro-Leyva, Sara Vega-García, Laura L Lugo-Salcedo, Leticia Manuel-Apolinar, Jennyfer M Gaspar-Gurza, Paola Sánchez-Ramos, Ivon K Ruiz-López, Rosalinda Sánchez-Arenas, Sandra Jarquín-López, Nilson A Contreras-Carreto","doi":"10.24875/GMM.25000295","DOIUrl":"https://doi.org/10.24875/GMM.25000295","url":null,"abstract":"<p><strong>Background: </strong>The menopause stage involves a significant reduction in circulating estrogen levels, resulting in notable changes to the cardiovascular, metabolic, bone, and immune systems. Monocyte chemoattractant protein-1 (MCP-1) is strongly associated with cardiovascular diseases and obesity. However, it is crucial to establish and clarify the relationship between MCP-1 and metabolic parameters in postmenopausal women.</p><p><strong>Objective: </strong>The objective of this study was to assess the relationship between MCP-1 concentrations and various anthropometric and metabolic markers in premenopausal and postmenopausal women.</p><p><strong>Material and methods: </strong>A case-control study, including 82 women (41 in postmenopausal stage, and 41 in premenopausal stage), was matched by body mass index (BMI). Insulin, estradiol, and C-reactive protein (CRP) levels were quantified by chemiluminescence and MCP-1 by enzyme-linked immunosorbent assays.</p><p><strong>Results: </strong>Age was 46.3 ± 2.4 years in premenopausal women and 55.6 ± 5.1 years in postmenopausal women. The MCP-1 level was higher in postmenopausal than premenopausal women (28.7 ± 10.4 vs. 21.3 ± 16.3 pg/mL, p = 0.04). The MCP-1 correlated with BMI (r = 0.39, p = 0.0001), waist circumference (r = 0.34, p = 0.002), CRP (r = 0.33, p = 0.03), high-density lipoprotein cholesterol (r = -0.28, p = 0.02), and visceral adipose tissue (VAT) (r = 0.38, p = 0.0001). Multiple stepwise regression analysis showed that VAT influenced the MCP-1 level.</p><p><strong>Conclusion: </strong>Menopausal status influences MCP-1 concentrations; however, the relationship of MCP-1 with VAT favors the activation of inflammatory mechanisms, outweighing the effects of hormonal status.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"67-72"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvia Giono-Cerezo, Yolanda López-Vidal, María D Alcántar-Curiel
{"title":"Bacterial infections and their association with female infertility: diagnostic and therapeutic perspectives.","authors":"Silvia Giono-Cerezo, Yolanda López-Vidal, María D Alcántar-Curiel","doi":"10.24875/GMM.M26001104","DOIUrl":"https://doi.org/10.24875/GMM.M26001104","url":null,"abstract":"<p><p>Infertility is a public health issue affecting millions of women of reproductive age worldwide. Bacterial infections caused by Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma hominis, and Ureaplasma urealyticum are among the most prevalent. They are associated with pelvic inflammatory disease, chronic endometritis, fallopian tube obstruction, impaired endometrial receptivity and implantation, and increased risk of ectopic pregnancy and pregnancy loss. Timely diagnosis using nucleic acid amplification testing represents the current standard, while advanced techniques, such as sequencing, enable the precise identification of pathogens and dysbiosis. The treatment of infections caused by these microorganisms involved the use of antibiotics, guided by the specific antimicrobial susceptibility pattern of each bacterium. Alternatives such as antioxidants, probiotics, or vaginal microbiota transplantation have been proposed for persistent infections. The clinical approach is interdisciplinary, incorporating imaging studies and inflammatory biomarkers. Understanding the pathogens and their interactions within the microbiome, along with the integration of reproductive medicine and clinical microbiology, provides valuable insights for managing and preserving female fertility.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"28-36"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ingeborg Becker, Adriana Ruiz-Remigio, I Shareny Espinosa-Ojeda, Eduardo Flores-Escobar, César Rivera-Benítez, Carlos Briones-Garduño, Gabriela Meneses, María E Rivera-Montiel, Fabián Correa-Morales
{"title":"Chagas disease in pregnant women of Mexico: challenges and opportunities for reducing maternal-fetal risk.","authors":"Ingeborg Becker, Adriana Ruiz-Remigio, I Shareny Espinosa-Ojeda, Eduardo Flores-Escobar, César Rivera-Benítez, Carlos Briones-Garduño, Gabriela Meneses, María E Rivera-Montiel, Fabián Correa-Morales","doi":"10.24875/GMM.25000280","DOIUrl":"10.24875/GMM.25000280","url":null,"abstract":"<p><strong>Background: </strong>Chagas disease in pregnant women remains a public health concern in Mexico, carrying risks to both maternal and fetal health.</p><p><strong>Objective: </strong>This study aims to review Chagas disease in pregnant women reported in Mexico, including a study of 22 pregnant women infected with Trypanosoma cruzi (T. cruzi), who were attended at the \"Hospital General de México.\"</p><p><strong>Material and methods: </strong>A review of the literature on Chagas disease in pregnant women from Mexico, and an analysis of data of 22 pregnant patients with Chagas disease from Hospital General was carried out.</p><p><strong>Results: </strong>The review of published data revealed higher rates of T. cruzi infections among pregnant women of Chiapas, Oaxaca, and Jalisco, with premature rupture of membranes being the most frequent complication. Patients from the study at Hospital General showed a T. cruzi infection rate of 14.6%, with the most frequently reported complication being abortions (50%), followed by gestational diabetes (37%). The study discusses the low sensitivity of the commercial serological test, highlighting discrepancies when compared to serological assays employing T. cruzi lineages from Mexico.</p><p><strong>Conclusions: </strong>To improve serological diagnosis, it is essential to incorporate antigens from Mexican T. cruzi lineages. Pregnant women with Chagas disease should be screened for gestational diabetes for the potential risk of Type 2 Diabetes.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"37-44"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan P Fernández-Hernández, Martha A Hernández-González, Blanca Vázquez, Iván Cruz-Aceves, Sergio E Solorio-Meza, Gabriela Borrayo-Sánchez
{"title":"Lipid profile in mexican women at cardiaovascular risk.","authors":"Juan P Fernández-Hernández, Martha A Hernández-González, Blanca Vázquez, Iván Cruz-Aceves, Sergio E Solorio-Meza, Gabriela Borrayo-Sánchez","doi":"10.24875/GMM.M26001109","DOIUrl":"https://doi.org/10.24875/GMM.M26001109","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular diseases are a leading cause of morbidity and mortality among women, particularly postmenopausal. Metabolic and social gender differences influence lipid profiles and cardiovascular risk. In Mexico, factors such as obesity, diabetes, hormonal contraceptive use, and limited healthcare access exacerbate this issue.</p><p><strong>Objective: </strong>To describe the lipid profile of Mexican women with high and very high cardiovascular risk, and compare it to that of men.</p><p><strong>Material and methods: </strong>A cross-sectional study from the REMEXDIS (Mexican Registry of Dyslipidemia) cohort. Clinical, demographic, and biochemical variables were analyzed in 17,532 patients (9536 women). Statistical tests were applied to identify sex-related differences.</p><p><strong>Results: </strong>Women had a higher body mass index and a lower rate of suspected familial hyper-cholesterolemia. Men had significantly higher levels of total cholesterol, low-density lipoprotein cholesterol, triglycerides, and glucose. However, women were more frequently classified as very high cardiovascular risk (59.44% vs. 35.90%; p = 0.01). Notably, 48.36% of dyslipidemic women were previously undiagnosed.</p><p><strong>Conclusions: </strong>Mexican women with cardiovascular risk exhibit distinct clinical and metabolic characteristics compared to men. These findings highlight the importance of gender-specific strategies for prevention, diagnosis, and management of cardiovascular disease in women.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"81-87"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriela Borrayo-Sánchez, Martín Rosas-Peralta, Martha A Hernández-González, Dania N Lima-Sánchez, Ana C Sepúlveda-Vildósola
{"title":"Sex differences in hospital mortality with the myocardial infarction code.","authors":"Gabriela Borrayo-Sánchez, Martín Rosas-Peralta, Martha A Hernández-González, Dania N Lima-Sánchez, Ana C Sepúlveda-Vildósola","doi":"10.24875/GMM.M26001110","DOIUrl":"https://doi.org/10.24875/GMM.M26001110","url":null,"abstract":"<p><strong>Background: </strong>There are differences in acute coronary syndrome (ACS), with a worse prognosis in women.</p><p><strong>Objective: </strong>To evaluate sex differences in presentation, management of the myocardial infarction code and in-hospital mortality in the National Registry of Acute Coronary Syndromes.</p><p><strong>Material and methods: </strong>A total of 62,118 adults (74% men and 26% women) with ST elevation myocardial infarction (STEMI) or non ST elevation myocardial infarction (NSTEMI) treated in 177 hospitals were included. Treatment and prognosis were compared.</p><p><strong>Results: </strong>Women had higher comorbidity and lower smoking rates. STEMI was more prevalent in men (73.0% vs. 63.6%), and Non ST Elevation-Acute Coronary Ayndrome (NSTE-ACS) was more prevalent in women (36.4% vs. 27.0%). Under the heart attack code, reperfusion rates were higher in men: percutaneous coronary intervention (PCI) 28.3% vs. 27.9%, fibrinolytic therapy (FT) 36.4% vs. 31.9%, and pharmaco-invasive strategy (PIS) 7.9% vs. 7.2%, respectively; non-reperfusion rates were higher in women (27.3% vs. 33%; p < 0.0001). Complications were more frequent in women, and mortality was also higher in women (15.3% vs. 10.4%; OR: 1.56; 95% CI: 1.48-1.65). In logistic regression, female sex, age, diabetes, and hypertension independently predicted in-hospital death.</p><p><strong>Conclusions: </strong>Women received less reperfusion, greater comorbidity and mortality, therefore timely and equitable care in the myocardial infarction code must be guaranteed.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"88-96"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Lourdes Basurto-Acevedo, Aurora De la Peña-Díaz, Paola Sánchez-Ramos, Marcia Hiriart-Urdanivia
{"title":"Cardiometabolic health in women: differences compared to men.","authors":"M Lourdes Basurto-Acevedo, Aurora De la Peña-Díaz, Paola Sánchez-Ramos, Marcia Hiriart-Urdanivia","doi":"10.24875/GMM.M26001133","DOIUrl":"10.24875/GMM.M26001133","url":null,"abstract":"<p><p>Cardiometabolic diseases such as type 2 diabetes, hypertension, dyslipidemia, and cerebrovascular disease, are among the leading causes of mortality in Latin America, with a significant impact on the female population. In Mexico, these conditions show a high and increasing prevalence, particularly among postmenopausal women, due to hormonal changes that negatively affect endothelial function, lipid metabolism, and insulin resistance. Abdominal obesity, prediabetes, and type 2 diabetes affect a substantial proportion of women, and tend to worsen with age. Female-specific factors such as menopause, polycystic ovary syndrome, and hypertensive disorders of pregnancy further increase cardiovascular risk. Hormonal transition influences the lipid profile by elevating markers such as lipoprotein (a), thereby increasing thrombotic risk. These sex-based differences in cardiovascular physiology, including heart size, electrical activity, and vascular response, necessitate a tailored approach to prevention, diagnosis, and treatment. Four key challenges are highlighted: recognizing pathophysiological differences, identifying risk factors during menopause, early detection and treatment of prediabetes and dyslipidemia, and strengthening primary healthcare with guidelines specifically designed for Mexican women.</p>","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"16-20"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The understanding of the female body from medical research.","authors":"Liz Hamui-Sutton","doi":"10.24875/GMM.M26001115","DOIUrl":"https://doi.org/10.24875/GMM.M26001115","url":null,"abstract":"","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"162 1","pages":"146-148"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}