Genetika最新文献_第4页

[Genes encoding hevein-like antimicrobial peptides WAMPs: Expression in response to phytohormones and environmental factors]. [hevin -like抗菌肽WAMPs的基因编码:对植物激素和环境因素的表达]。

Genetika Pub Date : 2016-11-01

E A Istomina, T V Korostyleva, N A Rozhnova, E A Rogozhin, V A Pukhalskiy, T I Odintsova

引用次数: 0

[The analysis of association between type 2 diabetes and polymorphic markers in the CDKAL1 gene and in the HHEX/IDE locus]. [2型糖尿病与CDKAL1基因和HHEX/IDE基因座多态性标记的相关性分析]。

Genetika Pub Date : 2016-11-01

D S Khodyrev, A G Nikitin, A N Brovkin, E Yu Lavrikova, N O Lebedeva, O K Vikulova, M Sh Shamhalova, M V Shestakova, M Yu Mayorov, V A Potapov, V V Nosikov, A V Averyanov

{"title":"[The analysis of association between type 2 diabetes and polymorphic markers in the CDKAL1 gene and in the HHEX/IDE locus].","authors":"D S Khodyrev, A G Nikitin, A N Brovkin, E Yu Lavrikova, N O Lebedeva, O K Vikulova, M Sh Shamhalova, M V Shestakova, M Yu Mayorov, V A Potapov, V V Nosikov, A V Averyanov","doi":"","DOIUrl":"","url":null,"abstract":"The increase in diabetes was noted at the turn of the 21st century. Patients with type 2 diabetes (T2DM) make up the majority of patients. Diabetes is a multifactorial disease. It arises from adverse effects of environmental factors on the body of genetically susceptible peoples. According to modern concepts, T2DM is a polygenic disease. Each of the involved genes contributes to the risk of developing of this disease. In our study, the association between polymorphic genetic markers rs7756992, rs9465871, rs7754840, and rs10946398 in the CDKAL1 gene and rs1111875 in the HHEX/IDE locus and T2DM in the Russian population were studied. Four hundred forty patients with type 2 diabetes and 264 healthy individuals without any signs of the disease were examined. The comparative analysis of distribution of genotypes and allele frequencies points to an association between polymorphic genetic markers rs7756992, rs9465871, and rs10946398 in the CDKAL1 gene and this disease. For the other polymorphic genetic markers (rs7754840 in the CDKAL1 gene and rs1111875 in the HHEX/IDE locus), no statistically significant associations are found. On the basis of these data, we can conclude that the CDKAL1 gene is associated with development of T2DM. For the HHEX/IDE locus, such an association is absent.","PeriodicalId":12707,"journal":{"name":"Genetika","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35769544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Phylogeny of firs (genus Abies, Pinaceae) based on multilocus nuclear markers (AFLP)]. [基于多位点核标记(AFLP)的冷杉(冷杉属，松科)系统发育]。

Genetika Pub Date : 2016-11-01

S A Semerikova, V L Semerikov

{"title":"[Phylogeny of firs (genus Abies, Pinaceae) based on multilocus nuclear markers (AFLP)].","authors":"S A Semerikova, V L Semerikov","doi":"","DOIUrl":"","url":null,"abstract":"To study the phylogenetic relationships, evolutionary history, and molecular systematics of firs (genus Abies), the phylogenetic reconstruction, based on nuclear multilocus markers—amplified fragment length polymorphism (AFLP)—was conducted. Using seven combinations of selective primers, 84 samples of 39 taxa were genotyped for 553 polymorphic AFLP loci. A comparison with our earlier chloroplast and mitochondrial phylogenies of the genus (in 2014) shows that the nuclear phylogeny generally is more congruent to the chloroplast tree. Most of the clades resolved by the chloroplast phylogeny were supported also in the AFLP tree. Employing the nuclear DNA-based tree, we revealed the presence of new groups and the differences in the topology of several clades. AFLP confirmed the monophyly of Asian species of section Balsamea and their sister position in relation to the American group of species of this section. As shown by the tree of chloroplast DNA, Asian species of section Balsamea do not form a monophyletic group, but belong to the clade comprising the majority of Asian species. Phylogenetically mitochondrial DNA data to a large extent are not congruent to the nuclear and chloroplast DNA trees, and are more in line with geographical distribution of species. Conflicts between nuclear and cytoplasmic phylogeny were analyzed. Taking them into account, we consider the hypothesis of a hybrid origin of particular groups of firs, including ancient hybridization in section Balsamea. A comparison of molecular data with traditional taxonomy of the genus is discussed.","PeriodicalId":12707,"journal":{"name":"Genetika","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35769541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Insulators can disrupt weak transcription derived from the white gene enhancer in Drosophila transgenic lines]. [在果蝇转基因系中，绝缘子可以破坏来自白色基因增强子的弱转录]。

Genetika Pub Date : 2016-11-01

O V Kyrchanova, N Y Postika, A F Parshikov, P G Georgiev

引用次数: 0

[Genetic diversity and differentiation of Siberian spruce populations at nuclear microsatellite loci]. [核微卫星位点上西伯利亚云杉种群的遗传多样性和分化]。

Genetika Pub Date : 2016-11-01

A N Kravchenko, A K Ekart, A Ya Larionova

{"title":"[Genetic diversity and differentiation of Siberian spruce populations at nuclear microsatellite loci].","authors":"A N Kravchenko, A K Ekart, A Ya Larionova","doi":"","DOIUrl":"","url":null,"abstract":"The results of the study of 21 populations of Siberian spruce (Picea obovata Ledeb.) from different parts of the species natural range by microsatellite (SSR) analysis of nuclear DNA are presented. Using nine loci developed for Picea abies (L.) Karst. and Picea glauca (Moench) Voss and detecting variation in Picea obovata, the parameters of intra- and interpopulation genetic diversity, as well as the degree of population differentiation, were determined. It was demonstrated that the population of Siberian spruce in the study was characterized by a relatively high average level of intrapopulation variability (H o = 0.408; H e = 0.423) and low interpopulation differentiation (F st = 0.048, P = 0.001) at this class of DNA markers. The genetic distance between populations ranged from 0.009 to 0.167, averaging 0.039. The isolated Magadan population, located in the extreme Northeast of Russia at a considerable distance from the main species range and characterized by the lowest genetic diversity among the studied populations, was maximally differentiated from the rest of the spruce populations. In addition, the steppe Ubukun population from Buryatia and the population from the Bogd Khan Uul Biosphere Reserve, Mongolia, were considerably different in the genetic structure from most populations of Siberian spruce, although to a lesser extent than the Magadan population. These findings are consistent with the results of previous studies of this species carried out using allozyme and microsatellite loci of chloroplast DNA and point to the prospects of using nuclear microsatellites as DNA markers to analyze the population genetic structure of Siberian spruce.","PeriodicalId":12707,"journal":{"name":"Genetika","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35770179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[SSR polymorphism of modern cultivars and autochthonous forms of the pear tree from North Caucasus]. [北高加索地区梨树现代品种和乡土品种的SSR多态性]。

Genetika Pub Date : 2016-11-01

I I Suprun, S V Tokmakov, I A Bandurko, E T Ilnitskaya

引用次数: 0

[Chromosomal localization of aromatic alcohol dehydrogenase fast-migrating isoenzyme Aadh1F (CAD1-F) gene in Triticum aestivum L. bread wheat]. 小麦中芳香醇脱氢酶快速迁移同工酶Aadh1F (CAD1-F)基因的染色体定位

Genetika Pub Date : 2016-10-01

A A Konovalov, I K Shundrina, E V Karpova, N P Goncharov, E Ya Kondratenko

{"title":"[Chromosomal localization of aromatic alcohol dehydrogenase fast-migrating isoenzyme Aadh1F (CAD1-F) gene in Triticum aestivum L. bread wheat].","authors":"A A Konovalov, I K Shundrina, E V Karpova, N P Goncharov, E Ya Kondratenko","doi":"","DOIUrl":"","url":null,"abstract":"Differences in isoenzyme pattern of aromatic alcohol dehydrogenase, NADP-AADH or CAD, were found in the Triticum aestivum L. winter bread wheat cultivars by the method of electrophoresis in the starch gel. A standard three-component spectrum is present in the cv. Zitnica (former Yugoslavia); additional fact-migrating isoenzymes appear in the cv. Novosibirskaya 9 (Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Russia). The presence of fast-migrating CAD isoenzymes is designated as FF phenotype; their absence, as 00 phenotype. Hybridological analysis was carried out; the excess of “null” genotypes was found in F2 progenies. Hybridization with nulli-tetrasomic lines of the chromosomes of the fifth homeologous group was conducted for the gene localization. The segregation analysis demonstrated the most probable localization of the CAD1-F gene in the chromosome 5A. The plants with FF and 00 genotypes differed in a number of chemical and anatomical traits, as well as in grain productivity. The results obtained are discussed in connection with the function of this enzyme in the wheat plant tissues.","PeriodicalId":12707,"journal":{"name":"Genetika","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35766109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Genetic polymorphism of Tulipa gesneriana L. evaluated on the basis of the ISSR marking data]. [基于ISSR标记数据的郁金香遗传多态性评价]。

Genetika Pub Date : 2016-10-01

A S Kashin, T A Kritskaya, I A Schanzer

{"title":"[Genetic polymorphism of Tulipa gesneriana L. evaluated on the basis of the ISSR marking data].","authors":"A S Kashin, T A Kritskaya, I A Schanzer","doi":"","DOIUrl":"","url":null,"abstract":"Using the method of ISSR analysis, the genetic diversity of 18 natural populations of Tulipa gesneriana L. from the north of the Lower Volga region was examined. The ten ISSR primers used in the study provided identification of 102 PCR fragments, of which 50 were polymorphic (49.0%). According to the proportion of polymorphic markers, two population groups were distinguished: (1) the populations in which the proportion of polymorphic markers ranged from 0.35 to 0.41; (2) the populations in which the proportion of polymorphic markers ranged from 0.64 to 0.85. UPGMA clustering analysis provided subdivision of the sample into two large clusters. The unrooted tree constructed using the Neighbor Joining algorithm had similar topology. The first cluster included slightly variable populations and the second cluster included highly variable populations. The AMOVA analysis showed statistically significant differences (F CT = 0.430; p = 0.000) between the two groups. Local populations are considerably genetically differentiated from each other (F ST = 0.632) and have almost no links via modern gene flow, as evidenced by the results of the Mantel test (r =–0.118; p = 0.819). It is suggested that the degree of genetic similarities and differences between the populations depends on the time and the species dispersal patterns on these territories.","PeriodicalId":12707,"journal":{"name":"Genetika","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35765700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[New single nucleotide polymorphisms of androgen receptor gene (AR) in the Russian breed of Dzhalginsky Merino sheep]. 俄罗斯扎尔金斯基美利奴羊雄性激素受体基因(AR)新单核苷酸多态性研究

Genetika Pub Date : 2016-10-01

V I Trukhachev, A Yu Krivoruchko, V S Skripkin, A N Kvochko, A N Kulichenko, D A Kovalev, S V Pisarenko, A S Volynkina, M I Selionova, M M Aybazov, O A Yatsyk

引用次数: 0

[Induction of transcription through the scs insulator leads to abnormal development of Drosophila melanogaster]. [通过scs绝缘体诱导转录导致果蝇发育异常]。

Genetika Pub Date : 2016-10-01

O V Kyrchanova, D V Leman, S V Toshchakov, M V Utkina, M V Tikhonov, A F Parshikov, O G Maksimenko, P G Georgiev

引用次数: 0