Global Cardiology Science & Practice最新文献

{"title":"Dissecting the difference: Left ventricular aneurysm versus pseudoaneurysm.","authors":"Muhammad Salman Sabri, Kyra Herman, Hussam Al Hennawi, Alexander Shpilman, James L West","doi":"10.21542/gcsp.2025.29","DOIUrl":"10.21542/gcsp.2025.29","url":null,"abstract":"<p><p>Left ventricular aneurysms (LVAs) and pseudoaneurysms (LVPs) are common complications following acute myocardial infarction (AMI), predominantly involving the anterior wall due to complete occlusion of the left anterior descending (LAD) artery. Both conditions are associated with heart failure, arrhythmias, and thromboembolic events. However, differentiating between LVA and LVP is crucial, as LVPs carry a higher rupture risk and require surgical management. We present a case of LVP, diagnosed using cardiac magnetic resonance imaging (CMRI), in a patient with chronic total occlusion of the LAD, which was managed surgically. This case emphasizes the critical role of imaging in guiding appropriate treatment decisions.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 3","pages":"e202529"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-promoting behaviors among patients with heart failure: A cross-sectional study in Georgia.","authors":"Tengiz Verulava, Revaz Jorbenadze","doi":"10.21542/gcsp.2025.33","DOIUrl":"10.21542/gcsp.2025.33","url":null,"abstract":"<p><p><b>Background:</b> The increase in the number of patients with heart failure in recent years is multifactorial and is partly due to an aging population, improved survival from acute cardiovascular events (e.g., myocardial infarction), and advances in primary and secondary prevention strategies that have extended life expectancy of patients. <b>Objective:</b> The purpose of this study is to evaluate health-promoting behaviors in patients with heart failure. <b>Methodology:</b> Using a cross-sectional, observational research method, 143 patients diagnosed with heart failure at the Chapidze Emergency Cardiology Center (Tbilisi, Georgia) were interviewed. The average age of the patients was 64.8 ± 9.2 years, 63% of whom were men. <b>Results and discussion:</b> The results showed a negative association between age and healthy eating habits, as well as a positive mental attitude. Higher education levels were associated with better health behaviors. The more knowledge patients had about their disease, the more likely they were to engage in health-promoting behaviors. Patients with a disease duration of >15 years were more likely to engage in healthy eating habits and maintain a positive mental attitude. Subjects implanted with a pacemaker/cardioverter had a low-confidence mental attitude. <b>Conclusions:</b> Interventions that promote healthy behaviors in patients with heart failure should be expanded, particularly in those who are older, less educated, have a longer disease duration, have low disease knowledge, and/or are implanted with a cardioverter/pacemaker. Future interventions should include educational, psychological, and behavioral support strategies tailored to individual needs to encourage health-promoting behaviors and maintain a positive mental attitude among patients with HF.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 3","pages":"e202533"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of radial arteriovenous fistula after transradial coronary intervention.","authors":"Priyadharshini Krishnaswamy, B S Arun, Vinay Ks, Shivanand S Patil","doi":"10.21542/gcsp.2025.32","DOIUrl":"10.21542/gcsp.2025.32","url":null,"abstract":"<p><p>Radial access for coronary interventions usually has fewer complications than the femoral route. An iatrogenic arteriovenous fistula (AVF) at the access site is a complication sometimes associated with coronary procedures, most often via the transfemoral route. However, it is rarely encountered with transradial access. We report a rare case of iatrogenic right radial arteriovenous fistula in a 52-year-old male following percutaneous transluminal coronary angioplasty (PTCA) via a right radial access. The increasing frequency of right radial access for coronary interventions necessitates awareness and recognition of this potential complication. Furthermore, necessary precautions should be taken to prevent its development.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 3","pages":"e202532"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of ITGA2 C807T and ITGB3 T1565C polymorphisms with platelet characteristics in hypertensive Azerbaijani patients.","authors":"Vafa Nazirova, Zumrud Ismibayli, Ismayil Gafarov, Faig Guliyev","doi":"10.21542/gcsp.2025.28","DOIUrl":"10.21542/gcsp.2025.28","url":null,"abstract":"<p><p><b>Objective:</b> Cardiovascular diseases (CVDs) are a leading cause of mortality worldwide, including in Azerbaijan. This study investigates the association of <i>ITGA2</i> (C807T) and <i>ITGB3</i> (T1565C) gene polymorphisms with platelet characteristics in Azerbaijani patients with arterial hypertension (AH), focusing on potential thrombotic risk. <b>Methods:</b> A total of 100 participants were examined, including 76 hypertensive patients and 24 controls. The hypertensive group was further subdivided based on comorbidities: ischemic heart disease (IHD) and type 2 diabetes mellitus (T2DM). Genotyping was performed using the massARRAY method. Platelet indices, including mean platelet volume (MPV), plateletcrit (PCT), and platelet large cell ratio (P-LCR), platelet distribution width (PDWsd) were evaluated. Statistical analysis was conducted using IBM SPSS Statistics 26, with correlation tests, ANOVA, and Chi-square tests to examine genotype distribution and platelet characteristics. <b>Results:</b> Carriers of the homozygous C/C genotype of the <i>ITGA2</i> gene and T/T genotype of the <i>ITGB3</i> gene exhibited the highest platelet counts and elevated MPV, suggesting a tendency toward increased platelet aggregation. Although all platelet parameters remained within the normal range, significant correlations were found between the <i>ITGA2</i> T allele and MPV, PDWsd, and LPCR in hypertensive patients (<i>p</i> < 0.05). The study indicates that patients with the T/T genotype of <i>ITGA2</i> and ITGB3 may have an elevated risk of thromboembolism. <b>Conclusion:</b> Integrin gene polymorphisms, particularly in <i>ITGA2</i> and <i>ITGB3</i>, are associated with altered platelet characteristics in Azerbaijani patients with arterial hypertension. These genetic markers could serve as predictors for thrombotic complications, providing insights into targeted prevention strategies in CVD management.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 3","pages":"e202528"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phrenic nerve and esophageal injury in pulsed field ablation versus radiofrequency and cryoablation.","authors":"Sarah Shadiqa, Mohammad Iqbal, Giky Karwiky, Chaerul Achmad","doi":"10.21542/gcsp.2025.30","DOIUrl":"10.21542/gcsp.2025.30","url":null,"abstract":"<p><p><b>Background:</b> Phrenic nerve injury (PNI) and esophageal injury are serious complications associated with atrial fibrillation (AF) ablation procedures. Pulsed field ablation (PFA), a non-thermal modality, has emerged as a promising alternative to conventional thermal ablation techniques, such as radiofrequency ablation (RFA) and cryoballoon ablation (CBA). <b>Objective:</b> To evaluate and compare the incidence of PNI and esophageal injury following PFA, RFA, and CBA in patients undergoing AF ablation. <b>Methods:</b> A systematic search of The Cochrane Library, MEDLINE, and EMBASE databases was conducted for studies published between 2014 and 2024. Cohort and case-control studies comparing PFA with RFA and/or CBA in relation to PNI and esophageal injury were included. Risk ratios (RRs) and 95% confidence intervals (CIs) were calculated using a random-effects model. <b>Results:</b> Eleven studies involving 4,603 patients were included in the analysis. The incidence of PNI was 0.23% with PFA, 0.63% with RFA, and 2.68% with CBA, respectively. A meta-analysis of five studies comparing PFA and CBA showed a significantly lower risk of PNI with PFA (RR 0.13, 95% CI [0.04-0.35]; <i>p</i> < 0.0001). No esophageal injury was reported in the PFA group, compared to 2.79% in the RFA group and 1.45% in the CBA group. Pooled analysis demonstrated that PFA significantly reduced the risk of esophageal injury compared to RFA (RR 0.06, 95% CI [0.01-0.29]; <i>p</i> = 0.0005) and CBA (RR 0.07, 95% CI [0.01-0.39]; <i>p</i> = 0.002). <b>Conclusion:</b> PFA is associated with a significantly lower risk of phrenic nerve and esophageal injury than RFA and CBA.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 3","pages":"e202530"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor's page.","authors":"Magdi H Yacoub","doi":"10.21542/gcsp.2025.34","DOIUrl":"https://doi.org/10.21542/gcsp.2025.34","url":null,"abstract":"","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 3","pages":"e202534"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of PDE5 inhibitors on cardiovascular outcomes.","authors":"Imad Ghantous, Mohamad Tlais, Ali El Khatib, Georges Ghantous, George Maroun, Anthony Challita, Mohamad Ayek, Giorgio Barmo, Maria Sahyoun, Georges El Kari","doi":"10.21542/gcsp.2025.31","DOIUrl":"10.21542/gcsp.2025.31","url":null,"abstract":"<p><p>Erectile dysfunction and cardiovascular disease share common underlying mechanisms, with the former being an early marker of cardiovascular risk. Phosphodiesterase-5 inhibitors, widely used as first-line therapy for erectile dysfunction, also exhibit systemic vasodilatory properties with potential cardiovascular implications. This systematic review evaluates their impact on cardiovascular outcomes in patients with coexisting erectile dysfunction and cardiovascular disease. A comprehensive analysis of 13 studies identified significant cardiovascular benefits, including reduced risks of myocardial infarction, heart failure, and overall mortality. The mechanisms underlying these effects include improved endothelial function, reduced systemic inflammation, and enhanced exercise capacity. Despite these benefits, neutral or adverse outcomes have been noted in specific conditions and populations, such as heart failure with preserved ejection fraction and post-stroke patients. These findings highlight the importance of patient-specific factors in determining the appropriateness of phosphodiesterase-5 inhibitors. These results underscore the potential of these therapies to provide cardioprotective effects while emphasizing the necessity for tailored treatment strategies to maximize benefits and mitigate risks in high-risk populations.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 3","pages":"e202531"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of patient information guides generated by LLMs for common cardiological procedures.","authors":"Suppraja Soundarrajan, Karine Vartanian, Rahul Bhakle, Thanuja Katakam, Kinnera Dhanwada, Karansher Singh Randhawa, Nikhitha Puvvala","doi":"10.21542/gcsp.2025.26","DOIUrl":"10.21542/gcsp.2025.26","url":null,"abstract":"<p><p><b>Introduction</b>: The use of artificial intelligence (AI) has advanced rapidly in the field of cardiology owing to its ability to process complex data and analyze electrocardiograms, echocardiography, and cardiac testing. AI tools, such as ChatGPT and Google Gemini, can provide evidence-based treatment recommendations using concise language, which can help in the early diagnosis of disease. <b>Methodology:</b> In this cross-sectional study, patient information brochures for three cardiological procedures (ECG, 2D echocardiography, and exercise stress testing) were generated using ChatGPT and Google Gemini. The total word count, sentence count, average words per sentence, and syllables for words were assessed using the Flesch-Kincaid Calculator. The similarity of the text was determined using the Quill Bot plagiarism tool. The reliability of the generated responses was analyzed and graded using the Modified DISCERN Score, which is a 5-point rating system that uses a set of uniform standards to assess the accuracy and dependability of consumer health-related data. Statistical analysis was performed using RStudio v4.3.2. Additionally, the simplicity and reliability scores were compared using Pearson's Coefficient of Correlation. The unpaired <i>t</i>-test was used to compare the responses. <b>Results:</b> Responses generated by ChatGPT and Google Gemini were observed to have no significant difference in the word count (<i>P</i> = 0.59), sentence count (<i>P</i> = 0.74), average word per sentence (<i>P</i> = 0.79), grade level (<i>P</i> = 0.06), similarity (<i>P</i> = 0.45), and reliability scores (<i>P</i> = 0.38) between ChatGPT and Google Gemini. However, the ease score was significantly better for Google Gemini-generated responses than for ChatGPT (<i>P</i> = 0.0044), indicating that the responses generated by Google Gemini are more easily readable and understandable. <b>Conclusions:</b> The study found a statistically significant difference between the average syllables per word and ease score. No significant differences were observed in the number of words, sentences, average words per sentence, grade level, similarity, or reliability scores. More AI technologies need to be evaluated in future studies, which should cover a wider range of illnesses.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 2","pages":"e202526"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13025549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147573756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of electrocardiographic alterations before and after bariatric surgery.","authors":"Shokoufeh Hajsadeghi, Aida Iranpour, Faranak Olamaeian, Ali Tayebi, Mahdis Gheitasi","doi":"10.21542/gcsp.2025.22","DOIUrl":"10.21542/gcsp.2025.22","url":null,"abstract":"<p><p><b>Background:</b> Obesity is a key risk factor for cardiac arrhythmia and sudden cardiac death. Additionally, morbid obesity is associated with an acquired elongation of the corrected QT interval, which could potentially lead to dangerous arrhythmias. In this study, we compare electrocardiography changes in patients with body mass index ≥40 before and after bariatric surgery. <b>Methods:</b> We enrolled 55 patients with severe obesity in this study. All patients underwent bariatric surgery; electrocardiography along with anthropometric data and laboratory tests before and at least six months after bariatric surgery were performed. <b>Results:</b> In total, 55 patients completed the study protocol (44 women and 11 men) and the mean age was 37.0 ± 10.5 years. Mean body mass index decreased from 46.7 ± 6.1 to 32.5 ± 5.1 (<i>P</i> < 0.0001) and the average variables of waist circumference, systolic and diastolic blood pressure, fasting blood sugar and glycated hemoglobin before and at least six months after bariatric surgery were significantly decreased (<i>P</i> < 0.0001). The postoperative assessment revealed a considerable decrease in the heart rate (<i>P</i> < 0.0001) and the corrected QT interval (<i>P</i> < 0.003). <b>Conclusion:</b> This study showed that in a select group of patients with severe obesity, the corrected QT interval was reduced at least 6 months following the procedure. Also, as we expected, we observed decrease in systolic and diastolic pressure, heart rate, fasting blood sugar, glycated hemoglobin, the body indices including body mass index and waist circumference notably.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 2","pages":"e202522"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13025551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147573714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous coronary artery dissection in a patient with a progestin-releasing intrauterine device.","authors":"Enad Haddad, Sudeep Nugooru, Tyler Lee, Prerana Sevella, Asoka Balaratna","doi":"10.21542/gcsp.2025.23","DOIUrl":"10.21542/gcsp.2025.23","url":null,"abstract":"<p><p>Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome (ACS), which predominantly affects women. This case report describes a 55-year-old female with SCAD potentially linked to a progestin-releasing intrauterine device (IUD) placed 1.5 years ago. The patient presented with acute chest pain and diaphoresis, and was eventually found to have ST-elevation myocardial infarction that led to coronary angiography, revealing type 1 SCAD from the proximal right coronary artery (RCA) to the mid-RCA with grade 3 thrombolysis in myocardial infarction (TIMI) flow distally. She was managed conservatively with antithrombotics, statins, and blood pressure control, achieving favorable outcomes without invasive intervention. The IUD was removed due to its potential role as a hormonal trigger. This case underscores the importance of considering SCAD in women presenting with ACS, particularly in those with hormonal risk factors.</p>","PeriodicalId":12669,"journal":{"name":"Global Cardiology Science & Practice","volume":"2025 2","pages":"e202523"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13025553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147573743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}