General dentistry最新文献_第4页

Preclinical assessment of leukocyte- and platelet-rich fibrin for inhibition of mandibular osteonecrosis. 富含白细胞和血小板的纤维蛋白对下颌骨坏死抑制作用的临床前评估。

General dentistry Pub Date : 2026-03-01

Viviann Ruocco-Vetucci, Rômulo Augusto Costa Chaves, Ana Cláudia Fernandes Ballan, Janaína Cristina de Freitas-Alvarenga, Tauyra Mateus, Pâmela Leticia Dos Santos, Joni Augusto Cirelli, Thallita Pereira Queiroz, Ana Paula Souza Faloni

{"title":"Preclinical assessment of leukocyte- and platelet-rich fibrin for inhibition of mandibular osteonecrosis.","authors":"Viviann Ruocco-Vetucci, Rômulo Augusto Costa Chaves, Ana Cláudia Fernandes Ballan, Janaína Cristina de Freitas-Alvarenga, Tauyra Mateus, Pâmela Leticia Dos Santos, Joni Augusto Cirelli, Thallita Pereira Queiroz, Ana Paula Souza Faloni","doi":"","DOIUrl":"","url":null,"abstract":"Considering that osteonecrosis of the jaw may be due to the antiangiogenic effect of bisphosphonates and that leukocyte- and platelet-rich fibrin (L-PRF) releases proangiogenic factors, this study hypothesized that L-PRF could prevent mandibular osteonecrosis in the surgical alveoli of rats treated with sodium alendronate (ALE) or zoledronic acid (ZOL). A sample of 42 male Holtzman rats aged 3 months was divided into 3 experimental groups receiving different forms of treatment (n = 14): ALE, 1 mg/mL/kg weekly; ZOL, 0.3 mg/mL/kg weekly; or saline solution as a control vehicle, 0.009 mg/mL/kg weekly. After 8 weeks of drug or vehicle administration, the mandibular first molars were extracted, and the sockets were enlarged with a spherical drill. The left socket in each animal was filled with L-PRF, and the right socket was left empty in a split-mouth model. Administration of ALE, ZOL, and VEH continued weekly until 7 or 28 days postextraction, when the animals were euthanized (n = 7 per experimental group per timepoint). Repair of the surgical alveoli was evaluated by means of microcomputed tomography and histomorphologic analyses. The statistical significance value was set at P < 0.05. Micrographs showed no intergroup (Dunn test) or intragroup (Wilcoxon test) differences in bone volume density among the different groups at either time period (P > 0.05). According to the histomorphologic analyses, at both 7 and 28 days some expanded sockets in the ALE and ZOL groups exhibited nonvital bone with empty osteocytic lacunae surrounded by an amorphous material and/or an intense inflammatory infiltrate, regardless of the experimental condition of the socket (filled or not filled with L-PRF). In addition, the bone surface had rounded margins and no cells. The results of this study suggest that the presence of L-PRF did not prevent the occurrence of osteonecrosis of the jaw.","PeriodicalId":12571,"journal":{"name":"General dentistry","volume":"74 2","pages":"22-29"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A practical model for integrated temporomandibular disorder assessment in the routine oral examination. 在口腔常规检查中综合评估颞下颌障碍的实用模型。

General dentistry Pub Date : 2026-03-01

Mahpareh Marefat, Duong Tran, Robert Maxwell Watson, Hayel Abdulghani, Matthew Fortino

{"title":"A practical model for integrated temporomandibular disorder assessment in the routine oral examination.","authors":"Mahpareh Marefat, Duong Tran, Robert Maxwell Watson, Hayel Abdulghani, Matthew Fortino","doi":"","DOIUrl":"","url":null,"abstract":"The COVID-19 era has seen an increase in orofacial pain related to temporomandibular disorders (TMDs). The increased relevance and awareness of these conditions, including the enactment of accreditation standards dictating the inclusion of TMD education in dental school curricula, highlights the need for a simplified TMD screening and evaluation model. A literature review was conducted to establish whether a widely accepted, comprehensive, and clinically practical approach to screening and evaluation for TMDs during routine oral examination was available. Previous studies and available medical and dental history forms were reviewed. While medical and dental history forms currently available to practitioners contain TMD-related questions, they are presented in a nonsequential, sporadic manner that may not lead to intuitive diagnosis from the dental practitioner. This article introduces a proposed model and questionnaire for incorporating TMD examinations into routine examinations. The inclusion of a more practical TMD screening and evaluation model in routine examination is intended to facilitate the dentist's identification and assessment of TMD signs and symptoms, leading to a more targeted approach in diagnosis and referral. This proposed model has not yet been validated clinically; the next steps include further development, implementation within a clinical setting, and evaluation of its effectiveness.","PeriodicalId":12571,"journal":{"name":"General dentistry","volume":"74 2","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Azithromycin in dentistry: a second-line antibiotic with specific indications. 阿奇霉素在牙科中的应用：一种具有特殊适应症的二线抗生素。

General dentistry Pub Date : 2026-03-01

Mark Donaldson, Jason H Goodchild

引用次数: 0

Evaluation of root canal morphology and additional mesiobuccal canals in maxillary molars in the West Texas region. 西德克萨斯地区上颌磨牙根管形态及附加中颊根管的评价。

General dentistry Pub Date : 2026-03-01

Alex Gonzalez, Michelle McAden, Silvia Rojas-Rueda, Carlos A Jurado

{"title":"Evaluation of root canal morphology and additional mesiobuccal canals in maxillary molars in the West Texas region.","authors":"Alex Gonzalez, Michelle McAden, Silvia Rojas-Rueda, Carlos A Jurado","doi":"","DOIUrl":"","url":null,"abstract":"This study aimed to evaluate the mesiobuccal root canal morphology of maxillary molars with cone beam computed tomography (CBCT), categorize the morphology according to the Weine classification, and quantify the prevalence of additional mesiobuccal canals. CBCT scans from patients in El Paso, Texas, were collected. A total of 422 scans (231 maxillary first molars and 191 maxillary second molars) that met the inclusion criteria were examined using 3-dimensional software. The number of canals in the mesiobuccal root at the coronal and apical thirds was recorded, and root canal morphology was categorized based on the Weine classification. Data analysis revealed that 80.5% of maxillary first molars had a second mesiobuccal (MB2) canal, with 77.9% showing an MB2 canal at the chamber level and 30.3% at the apex. In maxillary second molars, 37.2% had an MB2 canal, with 32.5% showing an MB2 canal at the chamber and 13.6% at the apex. The most prevalent Weine classification for maxillary first molars was type II (50.2%), followed by types III (27.7%), I (19.5%), and IV (2.6%); for second molars, the most prevalent was type I (63.4%), followed by types II (23.6%), III (9.3%), and IV (3.7%). The difference in MB2 prevalence between maxillary first and second molars was statistically significant (chi-square test; P < 0.05). These findings emphasize the complexity of maxillary molars and the critical role of CBCT in successful endodontic treatment.","PeriodicalId":12571,"journal":{"name":"General dentistry","volume":"74 2","pages":"46-50"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What every dentist needs to know about microplastics and dental materials. 每个牙医都需要知道的关于微塑料和牙科材料的知识。

General dentistry Pub Date : 2026-03-01

Lisa C D'Affronte, John K Brooks, Nasir Bashirelahi

{"title":"What every dentist needs to know about microplastics and dental materials.","authors":"Lisa C D'Affronte, John K Brooks, Nasir Bashirelahi","doi":"","DOIUrl":"","url":null,"abstract":"Microplastics (MPs), defined as plastic particles ranging from 1 μm to 5 mm, have become a growing concern with potentially significant implications for human health. Originating from diverse sources, including consumer products, industrial activities, and biomedical supplies, MPs have been detected in water, food, air, and even human tissues. This review focuses on the potential health risks and sources of MPs, particularly those arising from dental products. Dental products such as toothpastes, toothbrushes, dental floss, resin-based composites, denture base materials, and thermoplastic orthodontic appliances contain or generate MPs through degradation and routine use. Human exposure to MPs occurs via ingestion, inhalation, and dermal contact, with evidence suggesting systemic distribution that affects multiple organ systems, including the cardiovascular, nervous, and endocrine systems. MPs can cross critical biological barriers, leading to neurotoxicity, hormonal disruption, and potential carcinogenesis. The cumulative plastic waste from dental care contributes to environmental pollution. Emerging solutions such as biodegradable materials and improved waste management strategies show promise but require further investigation. This review underscores the need for continued research on MP exposure to mitigate health risks and environmental impact.","PeriodicalId":12571,"journal":{"name":"General dentistry","volume":"74 2","pages":"52-56"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging healthcare news. 新兴医疗保健新闻。

General dentistry Pub Date : 2026-01-01

John K Brooks, Nasir Bashirelahi

引用次数: 0

Evidence-based approach to apexification: a literature review and novel clinical protocol. 循证方法根尖矫正：文献回顾和新的临床方案。

General dentistry Pub Date : 2026-01-01

Yale Kim, Kishore Shetty

{"title":"Evidence-based approach to apexification: a literature review and novel clinical protocol.","authors":"Yale Kim, Kishore Shetty","doi":"","DOIUrl":"","url":null,"abstract":"Apexification, a well-established endodontic treatment for managing immature permanent teeth with pulp necrosis, aims to create a calcified apical barrier to seal communication with the periapical tissues and allow gutta percha placement. This literature review explores advancements of apexification and introduces a systematic, evidence-based procedure for achieving optimal outcomes for apexification procedures. The discussion compares the materials most commonly used in apexification: calcium hydroxide [Ca(OH)2], mineral trioxide aggregate (MTA), and Biodentine. Compared with Ca(OH)2, contemporary calcium silicate-based materials such as MTA and Biodentine have significantly greater predictability, biocompatibility, and fracture resistance, increasing the longevity of the immature tooth. In addition, the article discusses alternatives to apexification, including regenerative endodontic therapy. A review of the scholarly literature reveals that apexification has long been a cornerstone of treatment for immature permanent teeth with necrotic pulp, offering a predictable method to create a calcified barrier at the apex and enable tooth restoration. While apexification does not promote further root growth, it remains a reliable solution, particularly for cases requiring immediate treatment and a high degree of predictability.","PeriodicalId":12571,"journal":{"name":"General dentistry","volume":"74 1","pages":"28-33"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Painful and partially erupted odontoma: a case report. 疼痛及部分爆发的牙瘤1例。

General dentistry Pub Date : 2026-01-01

John K Brooks, Patricia K McAuley, Muhammad J Qazi, Ahmed S Sultan

引用次数: 0

Recurrence of clinical symptoms in an endodontically treated tooth following COVID-19 vaccination: a case report. COVID-19疫苗接种后牙髓治疗后临床症状复发1例报告

General dentistry Pub Date : 2026-01-01

Teng K Ong

{"title":"Recurrence of clinical symptoms in an endodontically treated tooth following COVID-19 vaccination: a case report.","authors":"Teng K Ong","doi":"","DOIUrl":"","url":null,"abstract":"The aim of this report is to present an unusual case in which clinical symptoms recurred in an endodontically treated tooth after the patient received a COVID-19 vaccination. A 61-year-old woman reported severe pain in her maxillary right lateral incisor 2 months after completion of root canal treatment. The patient reported developing the clinical symptoms a few days after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine. Clinical examination revealed no extraoral or intraoral swelling, but the incisor exhibited tenderness on percussion. Palpation of the surrounding tissue did not elicit any tenderness, and no sinus tract was observed. The periodontal probing depths were within normal limits. A periapical radiograph showed no significant change in the radiolucency associated with the treated tooth. The pain had lessened after the use of nonsteroidal anti-inflammatory drugs, and the patient declined any active treatment for the tooth. At the 2-year follow-up, the tooth was asymptomatic, and complete resolution of the periapical radiolucency was observed in radiographic and cone beam computed tomographic images. This case report describes a possible association between COVID-19 vaccination and the onset of self-limiting clinical symptoms in a tooth that had recently undergone endodontic treatment. This case is a reminder that the recurrence of symptoms does not necessarily indicate endodontic treatment failure. No absolute cause-effect relationship can be established between the vaccination the patient received and the recurrence of clinical symptoms in her endodontically treated tooth, but clinicians should not immediately propose an intervention for a tooth presenting with clinical symptoms if the patient has recently received a COVID-19 vaccination. Longer follow-up is needed to assess the success of endodontic treatment.","PeriodicalId":12571,"journal":{"name":"General dentistry","volume":"74 1","pages":"73-76"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of bioactive glass air abrasion on the bond strength of adhesive to caries-affected dentin. 生物活性玻璃空气磨耗对牙本质黏合剂结合强度的影响。

General dentistry Pub Date : 2026-01-01

Zahra Fattah, Fereshteh Shafiei, Shiva Sobhani

{"title":"Influence of bioactive glass air abrasion on the bond strength of adhesive to caries-affected dentin.","authors":"Zahra Fattah, Fereshteh Shafiei, Shiva Sobhani","doi":"","DOIUrl":"","url":null,"abstract":"The purpose of this study was to investigate the influence of bioactive glass (BAG) air abrasion on the microshear bond strength (μSBS) between caries-affected dentin and universal adhesive used in etch-and-rinse (E&R) or self-etching (SE) mode. A total of 40 extracted, caries-infected human molars were randomly divided into 4 treatment groups based on dentin surface treatment and etching mode: E&R, E&R/BAG air abrasion, SE, and SE/BAG air abrasion. The teeth were flattened to provide a caries-affected, midcoronal dentin surface. After restoration procedures, the caries-affected surfaces were submitted to μSBS testing. Two-way analysis of variance and Student t test were used to analyze the data, with significance set at P < 0.05. The E&R/BAG group had the highest mean (SD) μSBS, 23.66 (6.05) MPa, but the value was not significantly different from that of the E&R group without BAG air abrasion, 22.06 (7.51) MPa. However, air abrasion with BAG adversely influenced the μSBS of the adhesive in SE mode, resulting in values of 10.51 (2.01) MPa in the SE/BAG group compared with 17.45 (3.65) MPa in the SE group (P < 0.0001). In the groups subjected to BAG air abrasion, the etching mode had a significant effect on μSBS (P < 0.0001). Scanning microscopic evaluation revealed little difference between the E&R and E&R/ BAG groups in hybrid layer and resin tag formation, but BAG air abrasion resulted in fewer resin tags and less resin penetration when the adhesive was used in SE mode. Bioactive glass air abrasion did not have any adverse effects on the μSBS of universal adhesive used in E&R mode, while it did reduce the μSBS when the adhesive was used in SE mode.","PeriodicalId":12571,"journal":{"name":"General dentistry","volume":"74 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0