Genetics and Molecular Biology最新文献_第3页

A novel protein truncating mutation of TTC8 causes Bardet-Biedl Syndrome (BBS) in a Pakistani family. 一种新的TTC8蛋白截断突变导致巴基斯坦一个家庭的Bardet-Biedl综合征（BBS）。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2026-02-09 eCollection Date: 2026-01-01 DOI: 10.1590/1678-4685-GMB-2025-0020

Sana Fatima, Dong Sun, Jianguo Han, Ming Qiu, Safeer Ahmad, Muhammad Zubair, Muhammad Zeeshan Ali, Safdar Abbas, Maria Shafiq, Muhammad Muzammal, Hadia Gul, Jabbar Khan, Shiwei Du, Muzammil Ahmad Khan

{"title":"A novel protein truncating mutation of TTC8 causes Bardet-Biedl Syndrome (BBS) in a Pakistani family.","authors":"Sana Fatima, Dong Sun, Jianguo Han, Ming Qiu, Safeer Ahmad, Muhammad Zubair, Muhammad Zeeshan Ali, Safdar Abbas, Maria Shafiq, Muhammad Muzammal, Hadia Gul, Jabbar Khan, Shiwei Du, Muzammil Ahmad Khan","doi":"10.1590/1678-4685-GMB-2025-0020","DOIUrl":"10.1590/1678-4685-GMB-2025-0020","url":null,"abstract":"Bardet-Biedl syndrome (BBS) is a rare ciliopathic disorder that segregates in an autosomal recessive manner. Genetic studies have so far identified 26 BBS-associated genes worldwide. This study analyzed a multiplex consanguineous Pakistani family with Bardet-Biedl syndrome. Genetic analysis was performed using whole-exome sequencing and Sanger sequencing. Additionally, in silico predictions were performed for functional characterization of the identified mutation. Whole exome analysis of this family identified a novel nonsense mutation [(NM_144596: exon11:c.C1047G: p.(Tyr349*)] in the 11th exon of TTC8 gene. The identified mutation presumably leads to removal of four TPR domains and C-terminus portion. Structural analyses of mutant TTC8 protein showed substantial morphologic and interactional variations, suggesting a defective role of the TTC8 protein in BBSome complex and thus its involvement in disease progression. Identification of novel mutation has expanded the mutational spectrum of TTC8. Moreover, these findings will help in genotype-phenotype association, prenatal diagnosis and genetic counseling of families at risk of BBS syndrome.","PeriodicalId":12557,"journal":{"name":"Genetics and Molecular Biology","volume":"49 1","pages":"e20250020"},"PeriodicalIF":1.3,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phylogenomic analysis of Paracidovorax citrulli strains reveals the presence of two lineages in Brazil. 对巴西瓜瓜副酸菌株的系统基因组分析显示存在两个谱系。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.1590/1678-4685-GMB-2025-0046

David F Duarte, Lucas P Lucena, Marcelo H O Gonçalves, Ana M Benko-Iseppon, Flávia Aburjaile, Vasco Azevedo, Bertram Brenig, Marco A S Gama, Elineide B Souza

{"title":"Phylogenomic analysis of Paracidovorax citrulli strains reveals the presence of two lineages in Brazil.","authors":"David F Duarte, Lucas P Lucena, Marcelo H O Gonçalves, Ana M Benko-Iseppon, Flávia Aburjaile, Vasco Azevedo, Bertram Brenig, Marco A S Gama, Elineide B Souza","doi":"10.1590/1678-4685-GMB-2025-0046","DOIUrl":"10.1590/1678-4685-GMB-2025-0046","url":null,"abstract":"Paracidovorax citrulli is the causative agent of bacterial fruit blotch in melons and watermelons. This study used comparative genomic approaches of 17 Brazilian P. citrulli strains obtained from melons and watermelons to classify them into groups I and II and try to understand their genomic differences. The genomes of P. citrulli presented general characteristics similar to those shown for the genomes of the type strain of P. citrulli and reference strains of groups I and II. A phylogenomic analysis revealed two distinct groups of P. citrulli, in which most Brazilian P. citrulli strains were grouped with the strain representing group I. CRISPR-Cas analysis revealed the presence of two proteins, Cas3 and Cas10, in all Brazilian P. citrulli genomes. In addition, we observed the presence of two plasmids (pAMC6 and pAC53) in three Brazilian P. citrulli strains, all closely related to group I. The prediction of effector proteins revealed the XopE/AvrPphe protein as a differential between the strains of groups I and II. The present study will contribute to a more detailed understanding of aspects of host-pathogen interactions and will help improve the detection of strains from these groups, thus elucidating the population dynamics of Brazilian strains of P. citrulli.","PeriodicalId":12557,"journal":{"name":"Genetics and Molecular Biology","volume":"48 4","pages":"e20250046"},"PeriodicalIF":1.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12961662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147289555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural evolution of the whole mitochondrial genome and phylogenetic inference in snakes (Squamata: Serpentes), including the undescribed mitogenome of the Brazilian endemic and critically endangered pitviper Bothrops insularis. 蛇类（Squamata: Serpentes）全线粒体基因组的结构进化和系统发育推断，包括未描述的巴西特有和极度濒危的pitviper Bothrops insularis的有丝分裂基因组。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2026-01-30 eCollection Date: 2026-01-01 DOI: 10.1590/1678-4685-GMB-2024-0196

Igor Salles-Oliveira, José S L Patané, Milton Y Nishiyama-Júnior, Maria José J Silva

{"title":"Structural evolution of the whole mitochondrial genome and phylogenetic inference in snakes (Squamata: Serpentes), including the undescribed mitogenome of the Brazilian endemic and critically endangered pitviper Bothrops insularis.","authors":"Igor Salles-Oliveira, José S L Patané, Milton Y Nishiyama-Júnior, Maria José J Silva","doi":"10.1590/1678-4685-GMB-2024-0196","DOIUrl":"10.1590/1678-4685-GMB-2024-0196","url":null,"abstract":"Evolutionary analyses of mitogenomes have provided insights into species evolution and conservation. Studies on snakes revealed a higher diversity especially involving variation in tRNA clusters. However, despite the increase in assemblies in databases, the available information for Brazilian species remains scarce in mitogenomic surveys. Based on this, we sequenced and provided the first description of the mitogenome of Bothrops insularis, a critically endangered taxon. We also used the B. insularis assembly and 128 molecules available in databases up to March 2022 to explore rearrangements and evolution of the mtDNA under a phylogenomic perspective. Comparative analyses revealed 24 mitotypes due to rearrangements within four tRNA clusters and within control regions. Mitotype 1 (M1) and Mitotype 2 (M2) are restricted to Scolecophidia and M3 is highly distributed within Alethinophidia. In addition, the M3 is suggested as the most likely ancestral mitotype during the mitogenome evolution. Regarding Bothrops, we recovered the same mitotype for B. jararaca and B. insularis, which structure differs from other Bothrops species. Nucleotide variation suggests 1.5% divergence between B. jararaca and B. insularis. Therefore, we suggest that B. insularis can be considered an evolutionary significant unit, and the data generated herein can be valuable for insights into genome evolution and conservation.","PeriodicalId":12557,"journal":{"name":"Genetics and Molecular Biology","volume":"48 4","pages":"e20240196"},"PeriodicalIF":1.3,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12893195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146156686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phyllosphere microbiomes uncovered: Research trends, geographic disparities, and key microbial players. 层球微生物群揭示：研究趋势、地理差异和关键微生物参与者。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2026-01-23 eCollection Date: 2026-01-01 DOI: 10.1590/1678-4685-GMB-2025-0083

Isabel Cristina Cadavid, Érika Frydrych Capelari, Caroline Salvati, Rogerio Margis

{"title":"Phyllosphere microbiomes uncovered: Research trends, geographic disparities, and key microbial players.","authors":"Isabel Cristina Cadavid, Érika Frydrych Capelari, Caroline Salvati, Rogerio Margis","doi":"10.1590/1678-4685-GMB-2025-0083","DOIUrl":"10.1590/1678-4685-GMB-2025-0083","url":null,"abstract":"In recent years, significant efforts have been made to understand the phyllosphere microbiome. To clarify current research trends and identify knowledge gaps, we conducted a systematic review of the literature and investigated the methodologies used to analyze microbiome communities associated with plants, along with the objectives of these studies. Applying systematic review principles, we assessed 333 reports from the Web of Science database for eligibility. Articles were included if they presented original research on microbiomes associated with phyllosphere tissues identified by next-generation sequencing. Of these, 268 reports, published from 2009 to March 2025, were retrieved. These reports were used to extract data in a controlled and methodical manner. The analyses identified the most frequently studied plant species and primary tissues, the geographical locations sampled, the variables investigated in the phyllosphere microbiome, and the methodologies and tools employed. A comparison of the number of studies on below-ground (n=1562) versus above-ground tissue (n=375) underscores the relatively unexplored nature of above-ground research. We notice a surprisingly low number of studies from the Southern Hemisphere. Additionally, through data mining, we identify the most dominant bacteria and fungi reported in phyllosphere studies. Based on these findings, we offer recommendations for future research on the phyllosphere.","PeriodicalId":12557,"journal":{"name":"Genetics and Molecular Biology","volume":"49Suppl 1 Suppl 1","pages":"e20250083"},"PeriodicalIF":1.3,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12893196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146164967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gene expression analysis for feed efficiency trait in liver tissue of lactating Girolando cows. 泌乳吉兰多奶牛肝组织饲料效率性状的基因表达分析。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2026-01-19 eCollection Date: 2026-01-01 DOI: 10.1590/1678-4685-GMB-2025-0036

Daniele Ribeiro de Lima Reis Faza, Mariana Magalhães Campos, Thierry Ribeiro Tomich, Fernanda Samarini Machado, Luiz Gustavo Ribeiro Pereira, Robert Domingues, Ana Luiza Franco, Marta Fonseca Martins, João Cláudio do Carmo Panetto, Marcos Vinicius Gualberto Barbosa da Silva, Wanessa Araújo Carvalho, Marco Antonio Machado

{"title":"Gene expression analysis for feed efficiency trait in liver tissue of lactating Girolando cows.","authors":"Daniele Ribeiro de Lima Reis Faza, Mariana Magalhães Campos, Thierry Ribeiro Tomich, Fernanda Samarini Machado, Luiz Gustavo Ribeiro Pereira, Robert Domingues, Ana Luiza Franco, Marta Fonseca Martins, João Cláudio do Carmo Panetto, Marcos Vinicius Gualberto Barbosa da Silva, Wanessa Araújo Carvalho, Marco Antonio Machado","doi":"10.1590/1678-4685-GMB-2025-0036","DOIUrl":"10.1590/1678-4685-GMB-2025-0036","url":null,"abstract":"The selection of high feed efficiency (FE) animals impacts sustainability and profitability of beef and dairy cattle production systems. An approach to investigate the mechanisms of FE involves analyzing gene expression profile in liver. This study used residual feed intake as a metric of FE to select 10 Gir x Holstein crossbred cows (Girolando F1) divided into high (HE) and low (LE) FE groups. Hepatic biopsies were used for differential gene expression investigation using RNA-seq analyses which revealed 20,787 known genes mapped accordingly to the bovine reference genome. The comparison of HE and LE revealed 149 significantly differentially expressed genes (DEG), 41 up-regulated, and 108 down-regulated in the LE group. Among DEG, some stood out as potential candidate genes, including DLK1, CACNG4, SLC2A12, SLC26A4, DUOX2, and DUOXA2. Functional enrichment analyses showed pathways that potentially influence FE, such as the negative regulation of leukocyte migration, regulation of calcium channel activity, negative regulation of cell migration and adhesion, extracellular matrix (ECM) organization, and thyroid hormone synthesis. ECM composition and immune system roles were also highlighted. These results could help understanding the mechanisms related to FE in dairy cattle and the development of selection strategies to improve this trait.","PeriodicalId":12557,"journal":{"name":"Genetics and Molecular Biology","volume":"48 4","pages":"e20250036"},"PeriodicalIF":1.3,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12814931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146003470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Updating the frequency of CCR5Δ32 in Brazil: Descriptive analysis of malaria cases and controls from Acre State, Amazon region. 更新巴西CCR5Δ32的频率：亚马逊地区阿克里州疟疾病例和控制的描述性分析。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2026-01-16 eCollection Date: 2026-01-01 DOI: 10.1590/1678-4685-GMB-2025-0056

Marina Ziliotto, Joel Henrique Ellwanger, Jamille Gregório Dombrowski, Claudio Romero Farias Marinho, Alessandra Pontillo, José Artur Bogo Chies

引用次数: 0

Cytogenotoxicity of food preservatives in mammalian cells: A systematic review. 食品防腐剂在哺乳动物细胞中的细胞遗传毒性：系统综述。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1590/1678-4685-GMB-2025-0137

Thiago Guedes Pinto, Daniel V de Souza, Rogerio A Dedivitis, Ana Claudia M Renno, Daniel A Ribeiro, Daisy M F Salvadori

{"title":"Cytogenotoxicity of food preservatives in mammalian cells: A systematic review.","authors":"Thiago Guedes Pinto, Daniel V de Souza, Rogerio A Dedivitis, Ana Claudia M Renno, Daniel A Ribeiro, Daisy M F Salvadori","doi":"10.1590/1678-4685-GMB-2025-0137","DOIUrl":"10.1590/1678-4685-GMB-2025-0137","url":null,"abstract":"This systematic review investigates the cytogenotoxicity of various food preservatives in mammalian cells, including sodium benzoate and potassium sorbate, through a comprehensive analysis of studies retrieved from PubMed, SCOPUS, and Web of Science. An orderly search conducted in March 2025 identified 19 relevant studies (from an initial 594), which employed assays, such as the micronucleus test and the comet assay to assess DNA damage, and MTT assay and polychromatic/normochromatic erythrocytes (PCE/NCE) ratio for evaluating cytotoxicity. Among these, 13 studies (68 %) reported genotoxic effects, with sodium benzoate being the most frequently associated with micronucleus formation and chromosomal abnormalities. Additionally, 12 studies (63 %) described cytotoxic effects, evidenced by decreased cell viability, altered proliferation indices, or nuclear alterations. As for the quality assessment, 18 studies (out of 19) were categorized as strong (n = 15) or moderate (n = 3) and, therefore, we consider our findings to be trustworthy. In summary, the consistent association between exposure to food preservatives and cytogenotoxic outcomes highlights the importance of monitoring such compounds and establishing clearer safety thresholds to protect human health. Certainly, these findings are important for clarifying the role of biomarkers related to cytogenotoxicity due to food preservative consumption in humans.","PeriodicalId":12557,"journal":{"name":"Genetics and Molecular Biology","volume":"49 suppl 1","pages":"e20250137"},"PeriodicalIF":1.3,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12766372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of a novel unliked 12 X-STR typing assay for forensic purposes in an admixed Rio de Janeiro population sample. 在巴西混合人口样本中鉴定一种新的不喜欢的12x - str分型法。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2025-12-12 eCollection Date: 2025-01-01 DOI: 10.1590/1678-4685-GMB-2025-0015

Isadora C de Toledo E Mello, Maria Clara da Costa Simas, Rosane Silva, Rodrigo Soares de Moura Neto

{"title":"Characterization of a novel unliked 12 X-STR typing assay for forensic purposes in an admixed Rio de Janeiro population sample.","authors":"Isadora C de Toledo E Mello, Maria Clara da Costa Simas, Rosane Silva, Rodrigo Soares de Moura Neto","doi":"10.1590/1678-4685-GMB-2025-0015","DOIUrl":"10.1590/1678-4685-GMB-2025-0015","url":null,"abstract":"X-STR analysis offers novel pathways for exploring both paternal and maternal lineages, which is particularly valuable in parenthood testing where standard methods fail. Despite being limited in availability, these markers show promise in improving forensic analyses, especially with emerging technology such as Massively Parallel Sequencing (MPS). This study introduces a new X-STRs multiplex system that could increase discrimination power in complex cases, expanding marker diversity and complementing traditional markers. We selected 12 X-STR loci (DXS61071, DXS97199, DXS12310, DXS14221, DXS33963, DXS39152, DXS44734, DXS54471, DXS68748, DXS70370, DXS13932, and DXS14986) for the assay. Genomic DNA was extracted from 100 unrelated males and 104 females, in a sample population from Rio de Janeiro, amplified with custom-designed primers and subjected to capillary gel electrophoresis and MPS. Forensic efficiency evaluation revealed high values of the combined power of discrimination in males (cPDM ≥ 0.999999997) and females (cPDF ≥ 0.999999999999995), as well as combined paternity exclusion (cPE ≥ 0.99999). Among these markers, two exhibit high polymorphism, with multiple isoalleles distinguishable by their sequences, using MPS technology. The incorporation of these new X-STR markers multiplex system in conjunction with MPS analysis could potentially increase the power of discrimination in forensic analysis for mixtures and complex cases.","PeriodicalId":12557,"journal":{"name":"Genetics and Molecular Biology","volume":"48 4","pages":"e20250015"},"PeriodicalIF":1.3,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12704242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145756137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fungal diversity in larval diets of Melipona interrupta: Impacts on queen development and survival. 断头蜂幼虫日粮中真菌多样性对蜂后发育和存活的影响。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2025-12-12 eCollection Date: 2025-01-01 DOI: 10.1590/1678-4685-GMB-2025-0021

Luana Evillyn Vinente de Queiroz, Flavia da Silva Fernandes, Gabriel Garcês Santos, João Vicente Braga de Souza, Gislene Almeida Carvalho-Zilse

引用次数: 0

Sequenced genomes and chromosome mapping illuminate key aspects of satellite DNA biology in Drosophila gouveai and D. borborema (buzzatii cluster, repleta group). 基因组测序和染色体定位阐明了goveai和D. borborema （buzzatii cluster, repleta group）卫星DNA生物学的关键方面。

IF 1.3 4区生物学

Genetics and Molecular Biology Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.1590/1678-4685-GMB-2025-0133

Anna C Rossi, Ana M Laborne, Dora Y Barrios-Leal, Maura H Manfrin, Gustavo C S Kuhn

{"title":"Sequenced genomes and chromosome mapping illuminate key aspects of satellite DNA biology in Drosophila gouveai and D. borborema (buzzatii cluster, repleta group).","authors":"Anna C Rossi, Ana M Laborne, Dora Y Barrios-Leal, Maura H Manfrin, Gustavo C S Kuhn","doi":"10.1590/1678-4685-GMB-2025-0133","DOIUrl":"10.1590/1678-4685-GMB-2025-0133","url":null,"abstract":"Satellite DNAs are abundant components of the genomes of many eukaryotic species. They are composed of long and rather homogeneous arrays of tandem repeats that are typically located at the heterochromatin. They may contribute to the structural organization and regulatory dynamics of the genome. However, they evolve rapidly between species and changes in their sequences and abundance may contribute to the process of speciation. Here we used Illumina genomic sequencing raw data and the TAREAN bioinformatic tool to identify and characterize the most abundant satDNAs present in two sister species from the buzzatii cluster (repleta group): D. gouveai and D. borborema. We found five satDNAs, two are reported in these species for the first time (CDSTR138 and CDSTR230), two have already been reported (pBuM and DBC-150) and one is described here for the first time (CDSTR8). These satDNAs differ in both quantitative and qualitative terms between the two species. Most notoriously, the pBuM satDNA was found in D. gouveai, but it is virtually absent in D. borborema, despite their relatively recent divergence (<0.5My). We mapped these satDNAs to the chromosomes and found that most of them are located near or at the centromeres, with overlapping distribution in several locations.","PeriodicalId":12557,"journal":{"name":"Genetics and Molecular Biology","volume":"48 4","pages":"e20250133"},"PeriodicalIF":1.3,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12697916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145741973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0