Gigiena i sanitariia最新文献

{"title":"Electromagnetic environment in the workplace when using active means of information protection","authors":"Valentina N. Nikitina, Nina I. Kalinina, Ekaterina N. Dubrovskaya, Vladimir P. Plekhanov","doi":"10.47470/0016-9900-2023-102-8-800-805","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-8-800-805","url":null,"abstract":"Introduction.. Currently, there are a large arsenal of technical means designed to protect information processed by electronic computing equipment from unauthorized access and additional sources of electromagnetic fields of the radio frequency range (RF EMF) in the workplace. However, in the available literature there is practically no data on the hygienic assessment of the electromagnetic environment when using active means of information protection.
 The purpose of the research is to conduct research and hygienic assessment of the electromagnetic environment in the workplace when using technical means of active information protection.
 Materials and methods. Regulatory documents, systems, and principles of information protection of computer equipment objects, technical characteristics and operating modes of devices were studied. EMF levels were measured in rooms and workplaces with personal computers (PCs) when using information security tools, EMF exposure parameters were determined. A hygienic assessment of the electromagnetic environment was carried out.
 Results. The intensity of RF EMF generated by electromagnetic noise generators in the workplace has been established to depend on such many factors as the type of device, the antenna used, its location, distance from the antenna, and others.
 Limitations. There are no limitations of the study.
 Conclusion. Active information protection devices are increasingly being used and there is an obvious need for monitoring and carrying out measures to protect personnel from the adverse effects of RF EMF, including clarifying hygiene standards, developing technical solutions, and creating domestic selective EMF measuring instruments.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135148708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanisms of increasing stress tolerance during transcranial magnetic stimulation in people with intellectual work","authors":"Arnold N. Fleishman, Anastasia V. Yamshchikova, Ilya D. Martynov, Stanislav A. Petrovskiy, Tatyana V. Korablina","doi":"10.47470/0016-9900-2023-102-8-825-829","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-8-825-829","url":null,"abstract":"Introduction. In modern conditions humans are exposed to the high level of stress that causes the gain in psychosomatic disorders. The problem of tolerance to increasing stress is becoming more and more urgent. The study of the possibilities of the dorsolateral prefrontal cortex stimulation, which affects the mechanisms of autonomic regulation, is of clinical interest.
 The aim of the study is to research the mechanisms of the resistance to increasing stress after transcranial magnetic stimulation of the dorsolateral prefrontal cortex of the right hemisphere in young males engaged in mental work. 
 Materials and methods. Thirty four healthy male 20 to 22 years students were observed. Transcranial magnetic stimulation of the dorsolateral prefrontal cortex projection at the F4 point in the electrode system marked “10–20” was carried out with an individually determined stimulus intensity in the amount of 300 stimuli with a frequency of 1 Hz. Autonomic effects were evaluated using spectral analysis of heart rate variability before and after stimulation. Seven-test was used as a stress test.
 Results. The predominance of oscillations in the low frequency of heart rate variability, indicating sympathetic activation, was determined in the examined young men, engaged in mental labour. After stimulation of the prefrontal cortex, there was an increase in heart rate variability, to a greater extent very low frequency oscillations associated with the central mechanisms of parasympathetic activity. During the stress test, the increase in adaptive capabilities was manifested by a less pronounced decrease in heart rate variability in comparison to the reaction before stimulation. A model of the effect of stimulation of the dorsolateral prefrontal cortex on heart rate variability was proposed.
 Limitations. The study is limited to the evaluation of spectral parameters of heart rate variability in 34 young healthy students before and after transcranial magnetic stimulation of the dorsolateral prefrontal cortex.
 Conclusion. Stimulation of the prefrontal cortex increased the adaptive capabilities of the body and can be used to increase stress resistance in people with intellectual work.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hygienic assessment of the acoustic load on airport ground staff during ground handling of aircrafts","authors":"Alexander O. Karelin, Olga E. Filipchick, Gennadiy B. Yeremin","doi":"10.47470/0016-9900-2023-102-8-796-799","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-8-796-799","url":null,"abstract":"Introduction. Among the occupational factors having a harmful effect on the body of airport ground staff, noise dominates, the levels of which may exceed normative values. 
 The purpose of the study. To assess the acoustic loads on airport ground staff when working on the platform of a modern airport.
 Materials and methods. Noise measurements at the workplaces of airport ground staff of the profession “Duty “follow me” Driver” (hereinafter referred to as the Duty Driver) were carried out in accordance with GOST ISO 9612–2016. On the basis of the analysis of the working situation and the typical structure of the working day a measurement strategy based on the labour function was adopted. The CENTER 322 noise meter was used to measure the noise.
 Results. The basic duration of the Duty Driver’s working shift is 10.5 hours and the effective duration of the working day in the sector of the installation of the aircraft (AC) at the parking place (PP) is 4 hours. It is revealed that the greatest noise load on the Duty Officer occurs at the time of coordination of the AC on PP. The main and basic sources of noise in this case are the working turbines of the aircraft. The maximum sound pressure levels depended on the type of aircraft and ranged from 91.2 dBA for the Boeing-747 to 111.0 dBA for the AN-26. The equivalent sound pressure level for a 10.5-hour working day was 
 92.3 ± 3.4 dBA, for the effective duration of the working day (4 hours) – 96.5 ± 3.4 dBA. The maximum sound levels for most brands of modern aircraft do not exceed the standard parameters. Equivalent sound pressure levels exceed the established standards by 12.3–16.5 dBA.
 Limitations of the study. Since the Duty Driver was wearing a microphone on himself, there were uncertainties caused by the shielding and reflecting effects of the body.
 Conclusion. Duty Drivers are exposed to noise exceeding hygienic standards. This makes it possible to attribute the workplace of the Duty Officers to the harmful class of working conditions 3.2 according to the acoustic factor and makes it necessary for them to use personal protective equipment against noise when working on the platform.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of the air environment of the production premises 
 of the cobalt salts extraction unit","authors":"Alexander N. Nikanov, Valery P. Chashchin, Ekaterina V. Ulanovskaya, Andrey I. Zaichenko, Alena V. Shilnikovskaya, Andrey B. Gudkov, Olga N. Popova","doi":"10.47470/0016-9900-2023-102-8-806-810","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-8-806-810","url":null,"abstract":"Introduction. The introduction of new and modern methods of extracting metals from mineral ores in the metallurgical industry should be accompanied by an expert hygienic assessment of working conditions. 
 Materials and methods. The research was carried out at one of the metallurgical enterprises of the Murmansk region, which processes sulfide copper-nickel ores, produces electrolyte nickel, copper, cobalt, cobalt concentrate and precious metal concentrates. The characteristics of the air environment in the cobalt salt extraction department were carried out at the workplaces of hydrometallurgists based on the results of the analysis of fifty samples. Air samples were taken using individual samplers during 75.0% of the time of the work shift simultaneously at all three stages (sections) of cobalt salt extraction. The measurement of metals was performed by inductively coupled plasma atomic emission spectrometry.
 Results. Apparatchiks-hydrometallurgists body was estabished to be affected by a lot of harmful substances of complex composition, water-soluble and water-insoluble compounds of nickel and cobalt where the most significant. The content of water-soluble compounds of nickel and cobalt at all extraction sites of cobalt salts ranged from 0.0066–0.0236 mg/m3 and 0.0147–0.303 mg/m3, whereas water-insoluble – 0.0043–0.0150 mg/m3 and 0.002–0.0163 mg/ m3. The concentrations of copper, lead, cadmium compounds in the air of the working area did not exceed the MPC in all samples.
 Limitations. The study is limited of 50 air samples of the working areas of the metallurgical operators of the cobalt salt extraction department.
 Conclusion. Thus, modern methods of obtaining cobalt salts by extraction can pose a real threat to the health of workers in this production. The need to use correct models to assess and manage the risks of the harmful effects of water-soluble and water-insoluble metal compounds (nickel, cobalt) on human health requires the development of a special methodology for the implementation of hygienic regulation of their content in inhaled aerosol fractions of closed industrial premises.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135148704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probability of health preservation among employees of industrial enterprises, healthcare and educational institutions","authors":"Gennady A. Sorokin, Nikolay D. Chistyakov, Marina N. Kir’yanova, Irina D. Bulavina, Natalia N. Loginova","doi":"10.47470/0016-9900-2023-102-8-817-824","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-8-817-824","url":null,"abstract":"Introduction. For an integral quantitative assessment of working population health it is reasonable to use “the chance of being healthy” indicator.
 Objective: The objective of the study is to establish regularities in age trends of “being healthy” chances among various occupational categories and jobs.
 Materials and methods. Three thousand two hundred forty three healthcare, industrial enterprise and education workers were surveyed. The assessment criterion is the absence of any chronic cardiovascular, respiratory, digestive, musculoskeletal, nervous, genitourinary and dermal system diseases. Chances of being healthy (ChH1) were calculated according to formula: ChH1 (%)= 100 • Ki /K, where: Ki is the number of people in i-age group, who have none of the above-mentioned chronic diseases, К is total number of persons examined in i-age group. Fatigue state duration, as “hours of fatigue per working week”, was used as a physiological equivalent of occupational load. Managing, psychological, hygienic, and non-occupational causes of fatigue and stress among workers were analyzed.
 Results. The age trend in chances of being healthy in workers employed in three various occupational fields was studied. Regression models “Chances of being healthy – age” were designed for doctors and nurses, working males and females, workers and experts, heads. A change of ChH1 in workers of different age groups, different workloads, and depending on managing, psychological, hygienic, and non-occupational factors was reported. 
 Limitations. The study is limited to considering two indicators, characterizing the chances of being healthy and four groups of fatigue and stress causes (managing, psychological, hygienic, and non-occupational) among workers of three fields of activity: healthcare, industry, and education.
 Conclusions. Three periods in the age trend of workers’ chances for being healthy, which differ in the level and rate of reducing chances: 20–39 years old, 
 40–69 y.o. and 70 and over y.o., are distinguished. The annual decrease of chances for being healthy is 1.17% in 25–45-aged healthcare workers, 1.19% in industrial workers, and 0.89% among university employees. The chances of being healthy depend on managing, psychological, hygienic, and non-occupational factors of fatigue and load. A criterion and a scale for assessing the age trend of being healthy chances for workers are suggested.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health risk assessment for welders (retrospective study)","authors":"Vladimir P. Plekhanov, Marina N. Kir’yanova, Olga L. Markova","doi":"10.47470/0016-9900-2023-102-8-861-867","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-8-861-867","url":null,"abstract":"Introduction. A significant variety of exposure to harmful production factors of the welding process makes it difficult to assess the risk to the health of workers. Health risk assessment is an urgent task for the prevention of occupational and work-related diseases in welders.
 Objective. The objective of the work is to assess the health risk based on data on the incidence in welders at a modern industrial enterprise with varying intensity of exposure to factors of the working environment and the labour process.
 Materials and methods. Hygienic studies of the factors of the working environment and health risk assessment were carried out on the basis of 4 workshops of a large enterprise in 2007–2016. 
 Results. Priority classes of diseases according to ICD-10 in welders and locksmiths at a large industrial enterprise have been established. The calculation and assessment of the relative health risk were carried out according to the data of the medical and sanitary part of the enterprise on the temporary disability of employees, depending on age and work experience.
 Limitations. The study is limited to a retrospective risk assessment based on data from the electronic database of the enterprise for a 10-year period, taking into account cases of the disease according to ICD-10 in workers of two occupational groups exposed to welding aerosol to varying degrees.
 Conclusions. Health risk assessment for several forms of diseases can be a sensitive and informative indicator under conditions of varying intensity of exposure to production factors.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of polymorphic loci of candidate genes in patients with occupational diseases","authors":"Y. Chernyak, A. P. Merinova","doi":"10.47470/0016-9900-2023-102-7-689-694","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-7-689-694","url":null,"abstract":"Introduction. Development and progress features of vibration syndrome (VS) and noise-induced hearing loss (NIHL) are determined by genetic factors to a certain extent. The latter define the relevance of the search for individual approaches to  prevention and medical support of patients with these occupational diseases. \u0000The aim of the study was to investigate the genotypes distribution of polymorphic loci of candidate genes in patients with occupational diseases caused by vibration and noise impact. \u0000Materials and methods. Polymorphic variants of the HSPA1B (rs1061581), IL17A (rs2275913), IL10 (rs1800872), and TNF-α (rs1800629) genes of three hundred ninety eight males were studied using PCR-RFLP and real-time PCR methods, including 268  patients with VS divided into two groups: VShtv (n = 117) and VScomb (n = 151), in which VS was caused by exposure to hand-transmitted vibration (HTV) or combined exposure to HTV and whole-body vibration (COMB), respectively. The study also involved 96 patients with occupational NIHL diagnosis and 34 individuals of the comparison group without occupational contact with physical factors. \u0000Results. The increase in GG-HSPA1B (1267A/G) genotype frequency  (p=0.058) was found in VScomb patients compared with those from the VShtv group. There was a significant difference in carriers of the C/C genotype of the IL10 (rs1800872) polymorphic locus in the group of NIHL patients relative to the comparison group (p=0.036). The results of regression analysis indicate the carriage of the A allele to reduce the risk of NIHL development. \u0000Limitations. The limitations include the number of examined cases in all groups, especially in comparison group and the lack of groups of workers with no occupational exposure to a physical factor.   \u0000Conclusion. The obtained results expand the understanding of the genetic features able to determine sensitivity to the physical factors exposure that define the development of occupational pathology and the issues to be resolved at the next stage of research.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41317394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative assessment of the state of main arteries in workers of the pivotal occupations in the coal and aluminum industries","authors":"O. Korotenko, E. Filimonov, N. I. Panev, E. V. Ulanova","doi":"10.47470/0016-9900-2023-102-7-658-663","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-7-658-663","url":null,"abstract":"Introduction. To prevent cardiovascular accidents and preserve the employability in workers in the pivotal occupations of the coal and aluminum industries it is required timely identification of risk groups for long-term asymptomatic damage to the atherosclerotic process of the arteries. \u0000Material and methods. The study included two hundred twenty two miners and 109 workers in the aluminum industry aged of 40–55 years (average age of miners – 47.1 ± 0.36 years, metallurgists – 47.64 ± 0.43 years, р = 0.367). All subjects underwent ultrasound investigation of the carotid and femoral arteries. Also anamnestic, anthropometric data, the presence of arterial hypertension, indices of lipid and carbohydrate metabolism were evaluated. \u0000Results. Miners were more often diagnosed with intimal thickening (41.9% vs. 27.5%, p = 0.011), in contrast to aluminum production workers, who were significantly more likely to have atherosclerotic plaques (57.8% vs. 43.2%, p = 0.0127). The frequency of generally accepted risk factors for atherosclerosis in both occupational cohorts (arterial hypertension, smoking, carbohydrate metabolism disorders, physical inactivity, obesity) was detected without significant differences. Miners with atherosclerosis were diagnosed with significantly higher average values of total cholesterol and low-density lipoprotein cholesterol, metallurgists with atherosclerosis showed hypertriglyceridemia. \u0000Limitations. The study was limited by the number of the examined persons undergoing periodic medical examination at the Research Institute for Complex Problems of Hygiene and Occupational Diseases. \u0000Conclusion. A more significant lesion of the main arteries in the form of atherosclerotic plaques with varying degrees of stenosis was found in aluminum production workers compared to miners, which was probably due to the more aggressive influence of harmful production factors in metallurgists. In this regard, it is recommended to conduct a screening ultrasound investigation of the main arteries at a periodic medical examination, which will identify a risk group for the timely prevention of cardiovascular complications.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42774537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalized prediction of the probability of developing arterial hypertension and coronary heart disease in miners with anthracosilicosis using an automated system","authors":"N. I. Panev, S. N. Filimonov, R. N. Panev, N. Evseeva, O. Korotenko","doi":"10.47470/0016-9900-2023-102-7-675-681","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-7-675-681","url":null,"abstract":"Introduction. The remaining high level of production-related cardiovascular morbidity necessitates timely preventive measures. The development of an automated forecasting technique will make it possible to implement personalized and differentiated approaches in the prevention of cardiovascular pathology in persons in contact with harmful production factors. \u0000Materials and methods. The object of the study were workers employed in underground coal mining: One hundred sixty eight miners with previously diagnosed anthracosilicosis and 151 miners of the control group without lung pathology (a total of 319 people). Identification of diseases of the circulatory system and risk factors was carried out using clinical, laboratory, instrumental methods. The Bayes method was used to develop a forecasting system. The forecasting software as developed in the Lazarus environment using object-oriented programming methods. \u0000Results. The most informative markers associated with a high probability of developing arterial hypertension and coronary heart disease in workers with anthracosilicosis have been identified. A software “Automated system for personalized prediction of the probability of developing arterial hypertension and coronary heart disease in miners with anthracosilicosis” has been developed. An automated forecasting system determines the degree of risk of diseases based on the results of the sum of prognostic coefficients. \u0000Limitations. The limitation of the study was related to the sample of coal mine workers examined in the clinic of the Institute, namely: age from 40 to 54 years, long-term (more than 15 years) work experience in harmful working conditions. The study did not include miners who had other occupational diseases besides anthracosilicosis. \u0000Conclusions. An automated system of personalized forecasting ensures the formation of high cardiovascular risk groups with minimal time costs, which allows starting primary prevention of cardiological pathology in a timely manner.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43671761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of autonomic disorders in miners with vibration disease","authors":"A. V. Yamshchikova, A. Fleishman, I. Martynov","doi":"10.47470/0016-9900-2023-102-7-664-669","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-7-664-669","url":null,"abstract":"Introduction. Autonomic disorders in the form of autonomic neuropathy develop in vibration disease already at the early stages. As the disease progresses, the compensatory mechanisms of autonomic regulation are depleted, which leads to a worse prognosis for life and an increased risk of sudden cardiac death in patients with a severe degree of autonomic neuropathy. \u0000The aim of the study was to evaluate the severity of autonomic disorders and the preservation of compensatory reserves of autonomic regulation in patients with vibration disease. \u0000Materials and methods. One hundred thirty six miners with a proven diagnosis of vibration disease and 60 apparently healthy men of similar age without complaints and who had never worked under the conditions of exposure to industrial vibration were examined. Heart rate variability was analyzed at rest and during an active orthostatic test. \u0000Results. A decrease in the spectral parameters of heart rate variability in the patients with vibration disease was revealed. In a subgroup of the patients with an initially low level of very low frequency oscillations (less than 30 ms2/Hz), a decrease in the non-linear entropy index (less than 180) was determined; when performing an active orthostatic test, the power of very low frequency spectrum oscillations in the patients of this subgroup decreased by more than 50% of the initial values. In all patients with vibration disease under orthostatic load, a decrease in the oscillations of high and low frequencies of the spectrum of heart rate variability was revealed, whereas in the control group, the low frequency oscillation power remained at the initial level. \u0000Limitations. The study was limited to the evaluation of spectral and non-linear indices of heart rate variability in 136 miners with vibration disease. \u0000Conclusion. The criteria for a severe course of autonomic neuropathy in the patients with vibration disease were identified: an initial decrease in the power of very low frequency oscillations and a non-linear entropy index of heart rate variability, as well as a decrease in the power of very low frequency oscillations by more than 50% during an orthostatic test. According to these criteria, in 40.4% of the miners with vibration disease, pronounced violations of the autonomic support with a lack of compensatory mechanisms of autonomic regulation were found to be detected.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70834804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}