Frontiers in Public Health最新文献

{"title":"Move your body, stay away from depression: a systematic review and meta-analysis of exercise-based prevention of depression in middle-aged and older adults.","authors":"Xiao-Dong Zhao, Sae-Sook Oh, Zheng Zhang, Chong Wang","doi":"10.3389/fpubh.2025.1554195","DOIUrl":"10.3389/fpubh.2025.1554195","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to systematically assess the efficacy of exercise interventions in preventing depression among middle-aged and older adults. It further sought to dissect the impact of various intervention factors on the exercise-depression nexus within this demographic.</p><p><strong>Methods: </strong>We conducted a comprehensive search across multiple databases including PubMed, Embase, Web of Science, and the Cochrane Library, spanning from their inception through April 2024. The initial search yielded several studies, from which 11 papers involving a total of 792 subjects were selected based on predetermined inclusion criteria.</p><p><strong>Results: </strong>Our meta-analysis revealed a significant overall effect size (SMD = -3.64) with a 95% confidence interval of [-4.81, -2.48] and a <i>p</i>-value of <0.00001, underscoring the potent preventative impact of exercise on depressive symptoms in the target population. However, the studies exhibited substantial heterogeneity (<i>I</i> ² = 87%).</p><p><strong>Conclusion: </strong>Exercise interventions, particularly balance and gentle training as well as functional training, significantly reduce the risk of depression among middle-aged and older adults. The most pronounced effects were observed in group exercise settings and with exercise sessions lasting 30-40 min. Interventions of medium duration generally outperformed shorter-term interventions. Despite these promising results, the observed heterogeneity and other potential study limitations suggest a need for further research involving larger samples and more comprehensive study designs to refine and optimize exercise protocols for depression prevention in this population.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1554195"},"PeriodicalIF":3.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prioritizing mental and brain health in the global response to gender-based violence against women migrants and refugees.","authors":"Mohamed Taiebine","doi":"10.3389/fpubh.2025.1567898","DOIUrl":"10.3389/fpubh.2025.1567898","url":null,"abstract":"","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1567898"},"PeriodicalIF":3.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heat health assessment and risk simulation prediction in eastern China: a geospatial analysis.","authors":"Ming Li, Jiaying Xu","doi":"10.3389/fpubh.2025.1521997","DOIUrl":"10.3389/fpubh.2025.1521997","url":null,"abstract":"<p><strong>Background: </strong>High temperatures pose significant health risks and societal challenges in China, with spatial variations in heat health risks. Furthermore, due to the constraint imposed by heat health risk assessment on the construction of the public health security framework, it is necessary to explore the heat health risk pattern of spatial distribution and the trend of future risk development in eastern China.</p><p><strong>Methods: </strong>Based on the Intergovernmental Panel on Climate Change (IPCC) and Risk Triangle framework which is combined with natural and socio-economic factors, the heat health risk assessment index system of eastern China is established in this paper. This paper enhances the accuracy of risk maps with the aid of high-resolution imagery. It also focuses specifically on the exposure of construction workers in urban areas and agricultural workers in rural areas. This paper also evaluates the heat health risk of eastern China from 2010 to 2019 by using ArcGIS and the CA-Markov model.</p><p><strong>Results: </strong>The heat health risk in most areas of eastern China is predominantly highest risk, with the proportion of highest and medium risk areas increasing steadily from 2010 to 2019. The spatial distribution pattern reveals that high-risk areas are concentrated in the central urban areas, while low-risk areas are primarily in the mountainous regions, suburbs, rural areas, and water source areas. The conversion of heat health risk areas mainly occurs between adjacent levels, with no mutation process. From 2010 to 2025, the heat health risk of eastern China has been improving, and the overall distribution pattern of risk levels remains consistent.</p><p><strong>Conclusion: </strong>The research findings provide a basis for us to gain a deeper understanding of the vulnerability of different groups. This study not only presents spatial distribution maps of health risks, but offers a new perspective for us to comprehend the complexity and diversity of these risks. The research findings also establish a foundation for optimizing monitoring and warning systems. Furthermore, this study provides scientific evidence for policymakers to develop comprehensive heatwave mitigation plans. Nevertheless, we must acknowledge the limitations of the research and recognize that there is room for improvement in the future.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1521997"},"PeriodicalIF":3.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis and contrast of psoriasis disease burden trends in China and globally from 1990 to 2021.","authors":"Keyi Yu, Cheng Cao, Feilong An, Aie Xu, Xingang Wu","doi":"10.3389/fpubh.2025.1541292","DOIUrl":"10.3389/fpubh.2025.1541292","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to delineate the temporal tendency in the age and gender burden of psoriasis in China, spanning from 1990 to 2021, encompassing metrics such as incidence, prevalence, and disability-adjusted life years (DALYs). Furthermore, it sought to contrast these findings with the global disease burden. It also purposed to assess the impacts of age, time, and birth cohort, as well as to forecast the psoriasis burden in China for the upcoming 15 years.</p><p><strong>Methods: </strong>Utilizing open-access data from the Global Burden of Disease (GBD) database spanning 1990 to 2021, this study comprehensively examined the burden of psoriasis in China and globally. In China, a detailed analysis was conducted, emphasizing dimensions such as age, gender, and temporal trends. Join-point regression models were employed to calculate the average annual percentage change (AAPC). Furthermore, age-period-cohort (APC) analyses assessed the effects of age, time, and birth cohort, while an extended autoregressive integrated moving average model (ARIMA model) was used to forecast the psoriasis burden in China from 2022 to 2036.</p><p><strong>Results: </strong>Between 1990 and 2021, China experienced significant changes in its age-standardized incidence rate (ASIR), age-standardized prevalence rate (ASPR), and age-standardized DALY Rate (ASDR). Specifically, the ASIR rose from 48 per 100,000 in 1990 to 60 per 100,000 in 2021. Correspondingly, the ASPR increased from 362 per 100,000 in 1990 to 474 per 100,000 in 2021. Finally, the ASDR also showed an upward trend, climbing from 31 per 100,000 in 1990 to 41 per 100,000 in 2021. The AAPC of the ASIR, ASPR, and ASDR in China was 0.7434%, 0.8765%, and 0.8827%, respectively, significantly outpacing the global AAPC of 0.2204%, 0.2220%, and 0.2426%, respectively. The burden of psoriasis in China varied with age and gender, showing a trend of increasing and then decreasing ASIR, ASPR, and ASDR as age advanced. Women experienced lower incidence and prevalence rates of psoriasis than men. Over time, a delay in peak incidence was observed in both genders. The APC analyses revealed that psoriasis incidence initially increased and then declined with advancing age. Across all age groups, earlier birth cohorts had a relatively lower risk. Projections suggest that the incidence and prevalence of psoriasis in China will continue to rise over the next 15 years.</p><p><strong>Conclusion: </strong>Psoriasis poses a substantial public health challenge in China due to the country's large and increasingly aging populace. Mitigating this burden requires a multifaceted approach, including precise epidemiological research, an enhanced understanding of its socioeconomic determinants, and the development of effective health policies.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1541292"},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the application of policy instruments for close-knit county medical communities based on Hood's classification.","authors":"Huang Xianlu, Feng Lei","doi":"10.3389/fpubh.2025.1552590","DOIUrl":"10.3389/fpubh.2025.1552590","url":null,"abstract":"<p><strong>Objective: </strong>By analyzing the selection and application of policy instruments in the construction of close-knit county medical communities in Dazu District, Chongqing, this study aimed to propose countermeasures to optimize these policy instruments, offering valuable lessons for the construction of close-knit county medical communities.</p><p><strong>Methods: </strong>Based on Hood's classification, an analytical framework was constructed that incorporated the selection of basic policy instruments (X dimension) and the different phases in the construction process (Y dimension). Nvivo was used to analyze policy documents (2015-2023) related to the construction of close-knit county medical communities in Dazu District.</p><p><strong>Results: </strong>In the X dimension, the nodality-based instruments accounted for 14.3%, the authority-based instruments accounted for 34.2%, the treasure-based instruments accounted for 16.4%, and the organization-based instruments accounted for 35.2%. In the Y dimension, the total number of policy instruments used in Dazu District across the following three phases-policy initiation, piloting, and promotion-showed an increasing trend, aligning with the number of policies. These statistics indicated several issues such as limited use of nodality-based and treasure-based instruments, an incomplete policy assessment indicator system, insufficient policy synergy and incentives, and a lack of operationalization of strategic measures.</p><p><strong>Conclusion: </strong>The government should increase the use of nodality-based and treasure-based instruments, improve the assessment indicator system, strengthen policy synergy mechanisms and incentives, and optimize the structure of talent resources to improve the operability of the policies.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1552590"},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting the active aging situation in Bangladesh.","authors":"Sadiya Afrin, Md Mehedi Hasan Khan, Md Aminul Haque","doi":"10.3389/fpubh.2025.1517482","DOIUrl":"10.3389/fpubh.2025.1517482","url":null,"abstract":"<p><strong>Background: </strong>The older population in Bangladesh is growing rapidly, from 8.0% in 2020 to 22.0% in 2050. However, the determinants of active aging are scarcely known.</p><p><strong>Objective: </strong>The study aimed to assess the determinants influencing the active aging situation in Bangladesh.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 518 older adults aged 60 and over. Following the WHO active aging model, the respondents' socio-demographic, personal, behavioral, and physical environment and health and social services characteristics were collected using a semi-structured questionnaire. Multiple linear regression was performed to assess the effect of the determinants on active aging, followed by the bivariate level of analysis.</p><p><strong>Results: </strong>The determinants of active aging were deeply rooted in the respondents' socio-cultural, economic, and spatial conditions. Nine out of 23 determinants, like marital status, income, decision-making capacity, regular walking/physical exercise, smokeless tobacco consumption, newspaper reading as a leisure activity, use of medicine, and health service accessibility, significantly influence active aging. The active aging score was 10-15% higher among the respondents who regularly adhered to the above determinants.</p><p><strong>Conclusion: </strong>Effective initiatives are needed to improve the socio-cultural, economic, and health system-related determinants of active aging to enhance the active aging situation. Concerned bodies of the country, ministries, departments, and development partners should take appropriate measures to increase awareness and the participation of people in lifestyle-related determinants to improve the active aging situation in the country.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1517482"},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The combined impact of neutrophil-percentage-to-albumin ratio and depressive symptoms on mortality in US arthritis patients: insights from NHANES (2005-2018).","authors":"Jinyue Bai, Taihong Lv, Hanming Yu, Zishuo Ji, Xiu Gu, Yun Gao, Li Ma","doi":"10.3389/fpubh.2025.1545250","DOIUrl":"10.3389/fpubh.2025.1545250","url":null,"abstract":"<p><strong>Background: </strong>The neutrophil-to-albumin ratio (NPAR) reflects inflammation and nutritional status, while depression significantly impacts survival in chronic disease patients. This study examines the independent and combined effects of NPAR and depressive symptoms on all-cause and cardiovascular mortality in arthritis patients.</p><p><strong>Methods: </strong>We analyzed a nationally representative sample of people with arthritisaged 40 and older from NHANES (2005-2018). NPAR assessed inflammation and nutritional status, while depressive symptoms were measured by PHQ-9. Weighted Cox regression examined the independent and joint associations of NPAR and PHQ-9 with all-cause and cardiovascular disease (CVD) mortality.</p><p><strong>Results: </strong>Our analysis indicated that higher NPAR levels combined with lower depressive symptoms (PHQ-9 < 10) significantly increased all-cause and CVD mortality risks in arthritis patients. In this group, the hazard ratio (HR) for all-cause mortality was 2.087, with a similarly elevated CVD mortality risk (HR = 2.614), underscoring NPAR's predictive strength in non-depressed individuals. Among those with higher depressive symptoms, while elevated NPAR was still associated with increased mortality, its impact on CVD mortality was less marked, highlighting the need for further research into the NPAR-depression interaction.</p><p><strong>Conclusion: </strong>This study identifies NPAR as a key predictor of mortality in arthritis patients, particularly those with fewer depressive symptoms. NPAR significantly predicts all-cause and CVD mortality, underscoring its value as an inflammation and nutrition biomarker. Integrating NPAR in clinical practice could enhance individualized risk assessment and intervention for arthritis patients.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1545250"},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between organophosphate pesticide exposure and atopic dermatitis: a cross-sectional study based on NHANES 1999-2007.","authors":"YueHua Men, YiMeng Wang, WenTing Wu, Ming Chu","doi":"10.3389/fpubh.2025.1555731","DOIUrl":"10.3389/fpubh.2025.1555731","url":null,"abstract":"<p><strong>Background: </strong>Organophosphate pesticides (OPPs) are widely used environmental chemicals with potential health impacts, but their relationship with atopic dermatitis (AD) remains unclear.</p><p><strong>Methods: </strong>Using data from the National Health and Nutrition Examination Survey (NHANES) 1999-2007, we investigated associations between urinary OPP metabolites and AD in 4,258 adults. Six dialkyl phosphate (DAP) metabolites were measured, and weighted quantile sum (WQS) regression was used to assess mixture effects.</p><p><strong>Results: </strong>Both DMP (odds ratio [OR] = 1.17, 95% confidence interval [CI]: 1.05-1.31) and DMDTP (OR = 2.23, 95%CI: 1.08-4.60) showed significant positive associations with AD in fully adjusted models. WQS regression revealed significant associations between mixed OPP exposure and AD (OR = 1.25, 95%CI: 1.04-1.50), with DMP contributing most (45.8%) to the mixture effect. Stratified analyses indicated stronger associations in males, younger adults (<60 years), and smokers.</p><p><strong>Conclusion: </strong>Our findings suggest that OPP exposure, particularly DMP, may be associated with increased AD risk in adults. These results provide new insights into environmental risk factors for AD.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1555731"},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefits of musculoskeletal health promotion in school communities through service-learning: a mixed-method approach.","authors":"Sandra Calvo, Rocío Fortún-Rabadán, Sara Pérez-Palomares, Beatriz Carpallo-Porcar, Raquel Lafuente-Ureta, Carolina Jiménez-Sánchez","doi":"10.3389/fpubh.2025.1507730","DOIUrl":"10.3389/fpubh.2025.1507730","url":null,"abstract":"<p><strong>Background: </strong>Service-learning (S-L) is an educational method that enhances social and civic engagement among health science students, addressing unmet community needs. Musculoskeletal disorders (MSKD) represent a public health issue with increasing prevalence among school-aged population as reported by at least 1 on 5 children. Prevention programs for MSKD in schools are scarce, although evidence supports the efficacy of health education provided by physical therapists. This study aimed to evaluate the impact of a musculoskeletal health promotion program through S-L on school students, teachers, and physical therapy students.</p><p><strong>Methods: </strong>A mixed-methods approach was used. A quasi-experimental design assessed the learning and satisfaction of school students and teachers using pre-and post-intervention questionnaires. Additionally, qualitative data from reflective diaries of fourth-year physical therapy students were analyzed to capture their experiences. The intervention was conducted in 10 schools in Spain over two academic years, targeting children aged 10-14 and their teachers.</p><p><strong>Results: </strong>A total of 1,051 school students and 32 teachers participated. Pre-post evaluations revealed significant learnings on MSKD prevention and body awareness in both groups (<i>p</i> < 0.05), highlighting the increase in knowledge about MSKD prevention and self-treatment for school students and on MSKD derived from inadequate postures for schoolteachers. Satisfaction was high, with students and teachers rating the program 4.4/5. Teachers highlighted the value of training for their professional practice, while students appreciated learning about self-care. Physical therapy students were 4 and reflected on their motivation for the project, learning experiences, as well as positive and negative aspects of the service.</p><p><strong>Discussion: </strong>The S-L community-based intervention effectively increased awareness of musculoskeletal health and self-management skills. The peer learning environment and participatory approach encouraged engagement and knowledge retention in both students and teachers.</p><p><strong>Conclusion: </strong>S-L is a valuable strategy for promoting musculoskeletal health in schools while improving health education skills among the future physical therapists through experiential learning.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1507730"},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of ultraviolet radiation on filtering facepiece respirators and SARS-CoV-2 detection.","authors":"Khaled Al-Hadyan, Najla Al-Harbi, Sara Bin Judia, Maha Al-Ghamdi, Ibtihaj Alsharif, Layla Alharbi, Maha Al-Mozaini, Belal Moftah, Salem Al-Ghamdi, Ghazi Alsbeih","doi":"10.3389/fpubh.2025.1537742","DOIUrl":"10.3389/fpubh.2025.1537742","url":null,"abstract":"<p><strong>Introduction: </strong>The global coronavirus disease (COVID-19) pandemic of 2020 caused by SARS-CoV-2 resulted in a shortage of filtering facepiece respirators (FFRs), such as N95 and KN95 masks. Ultraviolet-C (UV-C) irradiation has been proposed as a potential decontamination method to enable FFR reuse and mitigate the shortage. This study aims to evaluate the impact of UV-C irradiation on the filtration efficiency (FE) of various FFR types and SARS-CoV-2 RNA degradation.</p><p><strong>Method: </strong>We evaluated the effect of UV-C irradiation (60-900 mJ/cm²) on the FE using various particle sizes (PSs, 0.3-5 μm) representing seven common FFR types (3M-8210, 3M-1860, Gerson 1730, Medline, Benehal, KN95 \"duck shape,\" and KN95 \"molded shape\") and the stability of the SARS-CoV-2 RNA genes (<i>E, RdRp2, RdRp4</i>, and <i>N</i>) using reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR).</p><p><strong>Results: </strong>Following UV-C exposure, the FE of the FFRs at all PSs was >98%, with no significant differences among them (<i>p</i> > 0.05). UV-C irradiation significantly increased the RT-qPCR cycle threshold values (ΔCt) for the <i>E</i>, <i>RdRp2</i>, and <i>RdRp4</i> SARS-CoV-2 genes (<i>p</i> ≤ 0.001) compared with the control, indicating marked RNA degradation; however, it did not significantly affect <i>N</i> gene stability (<i>p</i> = 0.612).</p><p><strong>Discussion: </strong>These results support the use of UV-C as an effective decontamination technique for FFRs, particularly during periods of shortage.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1537742"},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}