Frontiers in Public Health最新文献

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Unraveling meteorologically influenced recurrence and sequential infection risks among influenza, mumps, scarlet fever, and hand-foot-and-mouth disease: evidence from Shenzhen, China. 气象因素对流感、腮腺炎、猩红热和手足口病复发和顺序感染风险的影响:来自中国深圳的证据
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-27 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1920316
Hongxin Lyu, Huawei Xiong, Jue Liao, Lifang Cai, Yanpeng Cheng
{"title":"Unraveling meteorologically influenced recurrence and sequential infection risks among influenza, mumps, scarlet fever, and hand-foot-and-mouth disease: evidence from Shenzhen, China.","authors":"Hongxin Lyu, Huawei Xiong, Jue Liao, Lifang Cai, Yanpeng Cheng","doi":"10.3389/fpubh.2026.1920316","DOIUrl":"10.3389/fpubh.2026.1920316","url":null,"abstract":"<p><strong>Background: </strong>Meteorological factors are key triggers for infectious diseases in high-density cities, yet their influence on the acute disease patterns of influenza, mumps, scarlet fever, and hand-foot-and-mouth disease (HFMD) remains unclear. This study aims to reveal the variations in relative risk and secondary infection associated with meteorological factors, thereby providing clues for further confirmatory research.</p><p><strong>Methods: </strong>We analyzed city-wide incidence data from 2012 to 2020 alongside daily meteorological observations. Distributed lag non-linear models (DLNM) were used to quantify exposure-lag-response relationships. Andersen-Gill models assessed effects on disease recurrence, and Cox models evaluated risks of sequential infections between disease pairs, stratified by season.</p><p><strong>Results: </strong>The peak-risk temperatures were 14.5 °C for influenza, 18.5 °C for mumps, 17 °C for scarlet fever, and 28.5 °C for hand-foot-and-mouth disease (HFMD). Average temperature (AT) increase raised influenza recurrence risk (e.g., 1.3% higher risk per 1 °C in children aged 0-14 years). Greater temperature variability reduced sequential infection risk for influenza after HFMD in the cold season (Hazard Ratio [HR] = 0.16) and warm season (HR = 0.14). Increased diurnal temperature range also lowered this risk in the cold season (HR = 0.09). Higher AT in warm season reduced sequential infection risks from influenza to HFMD (HR = 0.61). Increased relative humidity was protective in the cold season but became a risk factor in the warm season in specific disease.</p><p><strong>Conclusion: </strong>Meteorological factors are pivotal in modulating the dynamics of common infections, and influencing both recurrence and sequential transmission. The protective effect of increased temperature variability against secondary infections highlights a complex climate-susceptibility interaction at the population level.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1920316"},"PeriodicalIF":4.1,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13523138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal trends and determinants of delayed care-seeking after rabies exposure: a 27,930-patient analysis in Tianjin. 狂犬病暴露后延迟就医的时间趋势和决定因素:天津27,930例患者分析
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-26 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1911137
Shuai Li, Shuangyan Liu
{"title":"Temporal trends and determinants of delayed care-seeking after rabies exposure: a 27,930-patient analysis in Tianjin.","authors":"Shuai Li, Shuangyan Liu","doi":"10.3389/fpubh.2026.1911137","DOIUrl":"10.3389/fpubh.2026.1911137","url":null,"abstract":"<p><strong>Objective: </strong>Prompt care-seeking after rabies exposure is essential for effective post-exposure prophylaxis (PEP). This study aimed to identify independent factors associated with care-seeking delay and to map the full PEP pathway.</p><p><strong>Methods: </strong>We retrospectively enrolled 27,930 patients attending the rabies PEP clinic at Santan Hospital, Tianjin, between February 2022 and January 2026. Delay was defined as >12 h from exposure to registration. Multivariable logistic regression, combined with XGBoost and SHAP, identified independent factors for delay and quantified their relative importance. Restricted cubic splines examined the non-linear relationship between age and delay. Subgroup analysis assessed the stability of the association of grade III exposure with more prompt care-seeking. A Sankey diagram traced the PEP pathway.</p><p><strong>Results: </strong>The delay rate was 29.7%. Eight independent factors were identified. Adults had a 34% higher risk of delay than children (aOR = 1.34, 95% CI: 1.22-1.47, <i>P</i> < 0.001). Grade III exposure was associated with more prompt care-seeking (aOR = 0.69, 95% CI: 0.65-0.73, <i>P</i> < 0.001). Previous rabies vaccination (aOR = 1.17, 95% CI: 1.11-1.23, <i>P</i> < 0.001) and inadequate wound management (aOR = 1.57, 95% CI: 1.31-1.88, <i>P</i> < 0.001) were associated with higher delay risk. Age showed a non-linear relationship with delay risk, with adults at highest risk. The Sankey diagram showed that inadequate wound management was rare in the PEP pathway, and the two-dose booster schedule achieved a much higher completion rate than the standard schedule.</p><p><strong>Conclusions: </strong>Our findings suggest that adults may face the highest risk of care-seeking delay, and that improving healthcare access for adults and promoting simplified vaccination schedules may be key to improving PEP quality.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1911137"},"PeriodicalIF":4.1,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13522977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exposure-relevant microplastic characteristics in drinking water and estuarine environments: environmental parameters for musculoskeletal experimental research. 饮用水和河口环境中与暴露相关的微塑性特征:肌肉骨骼实验研究的环境参数。
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-26 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1926761
Muhammad Adil Malik, Song Wu, Wenxiu Zhang, Junjie Huang, Xu Cao, Muhammad Salman Azhar
{"title":"Exposure-relevant microplastic characteristics in drinking water and estuarine environments: environmental parameters for musculoskeletal experimental research.","authors":"Muhammad Adil Malik, Song Wu, Wenxiu Zhang, Junjie Huang, Xu Cao, Muhammad Salman Azhar","doi":"10.3389/fpubh.2026.1926761","DOIUrl":"10.3389/fpubh.2026.1926761","url":null,"abstract":"<p><strong>Background: </strong>Microplastics are heterogeneous environmental contaminants whose transport, persistence, and potential biological interactions may depend on particle morphology, size, geometry, and polymer composition. Environmental monitoring studies commonly describe particle occurrence within individual matrices, whereas experimental studies frequently use standardized particles that may not adequately represent environmentally observed configurations.</p><p><strong>Objective: </strong>This study aimed to characterize microplastic morphology, dimensional characteristics, size distribution, and polymer composition in drinking-water and estuarine datasets and to identify environmentally observed particle profiles that may inform future musculoskeletal research.</p><p><strong>Methods: </strong>Two publicly available environmental datasets were analyzed separately. Overall morphology was summarized across 44,221 San Francisco Bay particle records with valid classifications. For matrix-level analyses, quality-assurance samples were excluded, and sample-level morphology proportions were compared using permutational multivariate analysis of variance based on Bray-Curtis dissimilarities with 9,999 permutations. Homogeneity of multivariate dispersion was assessed using PERMDISP. Particle length and aspect ratio were analyzed using generalized estimating equations accounting for particles clustered within samples and adjusted for environmental matrix. Drinking-water records were analyzed descriptively because of heterogeneity in observational units and analytical methods.</p><p><strong>Results: </strong>In the complete archived particle inventory, fibers were the most frequently recorded morphology (49.8%, <i>n</i> = 22,012), followed by fragments (40.3%, <i>n</i> = 17,804). Among 266 environmental or biological samples retained for inferential analysis after exclusion of quality-assurance samples, sample-level morphology profiles differed significantly among matrices (PERMANOVA pseudo-<i>F</i> = 34.14, R2 = 0.344, <i>p</i> < 0.001), although multivariate dispersion also differed (PERMDISP <i>F</i> = 94.31, p < 0.001). In cluster-adjusted models, fibers were approximately 2.51 times longer than fragments (95% CI, 2.35-2.68) and had 24.76 times their aspect ratio (95% CI, 22.70-27.01).</p><p><strong>Conclusion: </strong>Environmental microplastics occurred as heterogeneous combinations of fibers, fragments, particle sizes, and polymer categories. These environmentally observed combinations of morphology, dimensions, and material identity may provide empirically grounded parameters for selecting more representative particles in future cartilage-, synovium-, and bone-related experimental studies. However, this study does not measure human intake, internal exposure, tissue accumulation, biological responses, or musculoskeletal outcomes and therefore does not establish toxicological risk, clinical association, or causality.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1926761"},"PeriodicalIF":4.1,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13523142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between social capital, self-efficacy, and health-related quality of life in rural empty-nest older adults with chronic diseases: a latent profile and mediation analysis. 农村空巢老年人慢性病患者社会资本、自我效能和健康相关生活质量的关系:潜在特征和中介分析
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-21 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1866381
Yajuan Wang, Yu Zhao, Chunyu Tian, Limin Shi, Mengze Xu
{"title":"The relationship between social capital, self-efficacy, and health-related quality of life in rural empty-nest older adults with chronic diseases: a latent profile and mediation analysis.","authors":"Yajuan Wang, Yu Zhao, Chunyu Tian, Limin Shi, Mengze Xu","doi":"10.3389/fpubh.2026.1866381","DOIUrl":"10.3389/fpubh.2026.1866381","url":null,"abstract":"<p><strong>Background: </strong>Health-related quality of life is a key indicator of health status among rural empty-nest older adults with chronic diseases, who face limited social resources and a high disease burden. Although social capital is associated with quality of life, its heterogeneity and underlying mechanisms remain unclear. This study aims to identify distinct profiles of social capital using latent profile analysis, examine their effects on health-related quality of life, and test the mediating role of self-efficacy.</p><p><strong>Methods: </strong>A total of 425 rural empty-nest older adults with chronic diseases in Ningxia, China were surveyed between April and December 2025 using multistage stratified random sampling method combined with convenience sampling. Data were collected using the social capital scale, the self-efficacy scale, and the EuroQol five-dimension questionnaire (EQ-5D). All statistical analyses were performed using SPSS 27.0 and Mplus 8.3.</p><p><strong>Results: </strong>Latent profile analysis identified three social capital profiles: low (29.9%), moderate (49.4%), and high (20.7%). Health-related quality of life and self-efficacy differed significantly across profiles (<i>P</i> < 0.001). In mediation analyses using the low profile as the reference, the indirect effect of self-efficacy was not supported for the moderate profile (SE =0.014, 95% CI =-0.002, 0.053). In contrast, a significant indirect effect was observed for the high profile (SE =0.017, 95% CI =0.028, 0.095), with self-efficacy accounting for 21.2% of the total effect.</p><p><strong>Conclusion: </strong>Social capital was heterogeneous among rural empty-nest older adults with chronic diseases. The high social capital profile was associated with higher health-related quality of life and self-efficacy than the lower profiles. Self-efficacy partially mediated this association, whereas no significant indirect effect was found for the moderate profile. These findings support profile-informed interventions that enhance self-efficacy in individuals with high social capital and strengthen social capital in those with low or moderate social capital.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1866381"},"PeriodicalIF":4.1,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13522742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship among college students' social support, exercise motivation, and physical exercise behavior: a cross-lagged analysis. 大学生社会支持、运动动机与体育运动行为的关系:一个交叉滞后分析。
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-21 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1896136
Wensi Wan, Wentao Zhang, Ting Zhang
{"title":"The relationship among college students' social support, exercise motivation, and physical exercise behavior: a cross-lagged analysis.","authors":"Wensi Wan, Wentao Zhang, Ting Zhang","doi":"10.3389/fpubh.2026.1896136","DOIUrl":"10.3389/fpubh.2026.1896136","url":null,"abstract":"<p><strong>Objective: </strong>This study examines the dynamic relationship among social support, exercise motivation, and physical exercise behavior, and tests the longitudinal mediating role of exercise motivation between social support and subsequent exercise behavior.</p><p><strong>Methods: </strong>Using Jiangxi Normal University as the sample institution, a three-wave cross-lagged model was employed, with measurements taken every six months (T1, T2, T3); the final matched sample comprised 576 participants. Measurements were taken using the Social Support Scale, the Exercise Motivation Scale and the Physical Activity Level Scale.</p><p><strong>Results: </strong>The findings indicate that: (1) there are significant correlations between social support, exercise motivation and physical exercise behavior, both within and across time periods; (2) Cross-lagged analysis revealed that, across every two consecutive waves, there were significant bidirectional positive longitudinal associations between social support, exercise motivation and physical exercise behavior; (3) The results of the mediation analysis showed that social support at T1 had no significant direct predictive effect on physical exercise behavior at T3 [β = 0.006, 95% CI (-0.091, 0.103), <i>p</i> = 0.903]; however, it exerted a significant positive indirect effect on physical exercise behavior at T3 via exercise motivation at T2 [β = 0.019, 95% CI (0.006, 0.032), <i>p</i> = 0.004].</p><p><strong>Conclusion: </strong>These findings suggest that external support can only lead to sustained behavioral change when it is internalized as intrinsic motivation. Consequently, interventions should prioritize stimulating and maintaining exercise motivation, whilst making full use of the mutually reinforcing feedback loop between social support and exercise motivation, in order to achieve sustainable changes in health behaviors.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1896136"},"PeriodicalIF":4.1,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13494153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148791613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge-based Basic Life Support competency and associated factors among healthcare professionals across different hospital levels: a multicenter cross-sectional study. 基于知识的基本生命支持能力及其相关因素在不同医院级别的医疗保健专业人员:一项多中心横断面研究
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-20 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1881120
Pan Pan, YaXiong Zhou, YaoWen Jiang, YiQin Xia, TianYong Han, E Pan, Yao Chen
{"title":"Knowledge-based Basic Life Support competency and associated factors among healthcare professionals across different hospital levels: a multicenter cross-sectional study.","authors":"Pan Pan, YaXiong Zhou, YaoWen Jiang, YiQin Xia, TianYong Han, E Pan, Yao Chen","doi":"10.3389/fpubh.2026.1881120","DOIUrl":"10.3389/fpubh.2026.1881120","url":null,"abstract":"<p><strong>Background: </strong>Timely and effective Basic Life Support (BLS) is essential for improving survival after cardiac arrest. However, knowledge-based BLS competency among healthcare professionals (HCPs) working at different hospital levels has not been sufficiently characterized. This multicenter cross-sectional study aimed to assess knowledge-based BLS competency among HCPs and identify factors associated with high knowledge-based BLS competency.</p><p><strong>Methods: </strong>From March 2025 to March 2026, a cross-sectional survey of 2,017 HCPs (physicians, nurses, technicians, and other clinical staffs) was carried out in tertiary, secondary, and primary hospitals of Chengdu, Sichuan Province in urban areas. Demographic and professional characteristics, CPR training history, and BLS knowledge were assessed using an electronic questionnaire developed by the research team with reference to international BLS guidelines. The internal consistency of the questionnaire in the analytical sample was acceptable, with a Cronbach's alpha of 0.701. Descriptive statistics, chi-square tests, and multivariable regression analyzes were used to identify factors associated with knowledge-based BLS competency. A total BLS knowledge score of ≥80 points was classified as high knowledge-based BLS competency. Item-level accuracy and domain-specific knowledge scores were also calculated.</p><p><strong>Results: </strong>Overall, 40.26% of participants met the criterion for high knowledge-based BLS competency. In the unadjusted analyzes, professional role, hospital level, and educational level were significantly associated with high knowledge-based BLS competency. In the multivariable logistic regression model, physicians (OR = 3.01, 95% CI: 1.58-5.74) and nurses (OR = 2.46, 95% CI: 1.31-4.63) had significantly higher odds of achieving high knowledge-based BLS competency than technicians and other clinical staff. HCPs working in tertiary hospitals also had higher odds of achieving high knowledge-based BLS competency than those working in primary hospitals (OR = 1.48, 95% CI: 1.09-2.00). Core CPR knowledge had the highest domain-specific accuracy (87.43%), whereas defibrillation-related knowledge had the lowest accuracy (59.06%).</p><p><strong>Conclusion: </strong>Knowledge-based BLS competency among the surveyed HCPs working in the participating hospitals remained suboptimal, with particularly notable knowledge gaps in defibrillation-related topics. Professional role, hospital level, and educational background were associated with knowledge-based BLS competency. These findings support the development of standardized, regular, and targeted CPR education, particularly for lower-level hospitals and professional groups with relatively lower knowledge-based BLS competency.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1881120"},"PeriodicalIF":4.1,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between early menopause and adverse cardiovascular events in postmenopausal women: a systematic review and meta-analysis stratified by smoking status and type 2 diabetes mellitus. 绝经后妇女早期绝经与不良心血管事件之间的关系:吸烟状况和2型糖尿病分层的系统回顾和荟萃分析
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-20 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1906440
Zhongfang Chen, Xinyan Zhang, Yu Chen, Wen Shi, Chaoyue Ma, Xinyue Chen, Shuyu Yao
{"title":"Association between early menopause and adverse cardiovascular events in postmenopausal women: a systematic review and meta-analysis stratified by smoking status and type 2 diabetes mellitus.","authors":"Zhongfang Chen, Xinyan Zhang, Yu Chen, Wen Shi, Chaoyue Ma, Xinyue Chen, Shuyu Yao","doi":"10.3389/fpubh.2026.1906440","DOIUrl":"10.3389/fpubh.2026.1906440","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The impact of early menopause on adverse cardiovascular events may be modified by smoking and type 2 diabetes mellitus (T2DM). This study aims to investigate the effect of early menopause on adverse cardiovascular events in women, with stratification by smoking status and T2DM status.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Studies were retrieved from four databases (Embase, Web of Science, PubMed, and Cochrane Library) from their inception to January 2026. In this study, early menopause was defined as natural menopause occurring before age 45 years, encompassing both premature menopause (&lt;40 years) and early menopause (40-45 years). This systematic review was registered with PROSPERO (Registration No.: CRD420251238709). Results were presented as hazard ratios (HR) or relative risks (RR) with corresponding 95% confidence intervals (95% CI).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In this study, a total of seven cohort studies involving over 1.77 million postmenopausal women were included. Among non-smoking women, early menopause was associated with a higher risk of heart failure (HF: HR = 1.23, 95% CI = 1.02-1.49, &lt;i&gt;p&lt;/i&gt; = 0.031, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 87.9%, &lt;i&gt;n&lt;/i&gt; = 2) and coronary heart disease (CHD: RR = 1.26, 95% CI = 1.18-1.35, &lt;i&gt;p&lt;/i&gt; &lt; 0.001, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 0.0%, &lt;i&gt;n&lt;/i&gt; = 2). In contrast, among smoking women, we did not find statistically significant evidence of an association between early menopause and either HF (HR = 1.15, 95% CI = 0.88-1.52, &lt;i&gt;p&lt;/i&gt; = 0.311, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 73.7%, &lt;i&gt;n&lt;/i&gt; = 2) or CHD (RR = 1.63, 95% CI = 0.90-2.96, &lt;i&gt;p&lt;/i&gt; = 0.105, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 97.2%, &lt;i&gt;n&lt;/i&gt; = 2). For women without T2DM, early menopause was associated with a higher risk of both HF (HR = 1.19, 95% CI = 1.00-1.43, &lt;i&gt;p&lt;/i&gt; = 0.050, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 94.1%, &lt;i&gt;n&lt;/i&gt; = 2), a borderline finding that should be interpreted with caution, and significantly associated with stroke (HR = 1.11, 95% CI = 1.09-1.13, &lt;i&gt;p&lt;/i&gt; &lt; 0.001, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 0.0%, &lt;i&gt;n&lt;/i&gt; = 2). For women with T2DM, early menopause was associated with a higher risk of HF (HR = 1.29, 95% CI = 1.11-1.50, &lt;i&gt;p&lt;/i&gt; = 0.001, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 54.3%, &lt;i&gt;n&lt;/i&gt; = 2), but not find with stroke risk (HR = 1.11, 95% CI = 0.99-1.25, &lt;i&gt;p&lt;/i&gt; = 0.062, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 59.6%, &lt;i&gt;n&lt;/i&gt; = 2). In both the T2DM and non-T2DM groups, no statistically significant evidence of an association between early menopause and with all-cause mortality was found (T2DM: HR = 1.20, 95% CI = 0.83-1.74, &lt;i&gt;p&lt;/i&gt; = 0.333, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 54.3%, &lt;i&gt;n&lt;/i&gt; = 2; without T2DM: HR = 1.18, 95% CI = 0.94-1.47, &lt;i&gt;p&lt;/i&gt; = 0.148, &lt;i&gt;I&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 53.3%, &lt;i&gt;n&lt;/i&gt; = 2, respectively).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Early menopause is associated with the risk of adverse cardiovascular events in women, with divergent results by smoking status and T2DM.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Systematic review registration: &lt;/strong&gt;https://www.crd.york.ac.uk/PROSPERO/","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1906440"},"PeriodicalIF":4.1,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13538119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Tai Chi-based combined interventions on muscle function, muscle mass, and physical performance in older adults with sarcopenia, frailty, or risk of functional decline: a systematic review and meta-analysis. 以太极为基础的联合干预对肌肉减少症、虚弱或功能衰退风险的老年人肌肉功能、肌肉质量和身体表现的影响:系统回顾和荟萃分析
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-20 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1891703
Xudong Jin, Enliang Hu, Caiduo Shi
{"title":"Effects of Tai Chi-based combined interventions on muscle function, muscle mass, and physical performance in older adults with sarcopenia, frailty, or risk of functional decline: a systematic review and meta-analysis.","authors":"Xudong Jin, Enliang Hu, Caiduo Shi","doi":"10.3389/fpubh.2026.1891703","DOIUrl":"10.3389/fpubh.2026.1891703","url":null,"abstract":"<p><strong>Background and objective: </strong>Sarcopenia and frailty involve declines in muscle strength, muscle mass, and physical performance, and single Tai Chi may be insufficient to cover all functional needs. Tai Chi-based combined interventions have emerged, but their overall effects remain unclear. This study evaluated their effects in older adults with sarcopenia, frailty, or risk of functional decline.</p><p><strong>Methods: </strong>We systematically searched PubMed, Embase, CENTRAL, Web of Science, Scopus, CINAHL, ClinicalTrials.gov, CNKI, Wanfang, and VIP from database inception to May 12, 2026. Randomized controlled trials and cluster-randomized controlled trials comparing Tai Chi-based combined interventions with non-exercise, active-exercise, or single Tai Chi controls were included. Risk-domain composite standardized mean differences (SMDs) were used for the primary analysis, assuming rho = 0.5. A restricted maximum-likelihood random-effects model with Hartung-Knapp adjustment was applied. Risk of bias was assessed using the Cochrane Risk of Bias 2 tool, and certainty of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation approach.</p><p><strong>Results: </strong>A total of 21 studies (22 reports) were included, of which 16 contributed to quantitative synthesis. In the core layer, compared with active exercise control, combined interventions showed a potentially favorable estimate in the frailty/overall physical performance domain (SMD = 0.63, 95% CI: 0.05-1.21), whereas muscle function and muscle mass/quality estimates remained uncertain. Compared with non-exercise control, the muscle function domain (SMD = 1.00, 95% CI: 0.12-1.88) and frailty/overall physical performance domain (SMD = 1.35, 95% CI: 0.38-2.31) showed favorable estimates, whereas muscle mass/quality did not improve consistently. Among 14 GRADE bodies of evidence, 2 were Low and 12 Very low, with none Moderate or High.</p><p><strong>Conclusion: </strong>Tai Chi-based combined interventions may improve selected aspects of muscle function and overall physical performance, but the evidence was based on few heterogeneous studies and was of Low or Very low certainty. Additional benefits over active exercise or single Tai Chi, as well as the optimal intervention combination and dose, remain uncertain.</p><p><strong>Systematic review registration: </strong>The systematic review was registered in PROSPERO (CRD420261387528) https://www.crd.york.ac.uk/PROSPERO/view/CRD420261387528.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1891703"},"PeriodicalIF":4.1,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13538022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Problematic generative AI use and mental health risks among Chinese university students: latent profiles, network structure, and health literacy as a modifiable resource. 中国大学生有问题的生成人工智能使用和心理健康风险:潜在概况、网络结构和健康素养作为可改变的资源
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-20 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1910408
Zeyu Zhang, Yinlan Zhang, Xiaomei Lu, Min Zhang
{"title":"Problematic generative AI use and mental health risks among Chinese university students: latent profiles, network structure, and health literacy as a modifiable resource.","authors":"Zeyu Zhang, Yinlan Zhang, Xiaomei Lu, Min Zhang","doi":"10.3389/fpubh.2026.1910408","DOIUrl":"10.3389/fpubh.2026.1910408","url":null,"abstract":"<p><strong>Objective: </strong>Generative artificial intelligence (GenAI) has become a routine academic tool for university students, but dysregulated use may co-occur with anxiety, sleep problems, psychological distress, and impaired academic functioning. This study examined GenAI-related digital behavior as a public health issue and assessed whether health literacy and self-regulated learning were associated with lower-risk profiles.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted among Chinese university students from six universities in eastern, central, and western China. A total of 2,140 questionnaires were submitted; after four-step data-quality screening, 1,872 valid responses were retained. Measures assessed GenAI-use dysregulation, academic anxiety, sleep problems, psychological distress, health literacy, self-regulated learning, academic engagement, and demographic and use-related covariates. Latent profile analysis identified GenAI-use and mental-health risk profiles. Profile differences were examined using omnibus and <i>post hoc</i> tests, multinomial logistic regression examined external factors associated with profile membership, and regularized network analysis identified central and bridge nodes.</p><p><strong>Results: </strong>A four-profile solution showed the best balance of fit, entropy, class size, and interpretability (entropy = 0.891). The profiles were low-risk adaptive users (39.9%), anxiety-prone dependent users (25.7%), sleep-disrupted overusers (19.8%), and high-risk dysregulated users (14.6%). Confirmatory factor analysis supported the measurement structure of the adapted and selected scales (CFI = 0.958, TLI = 0.951, RMSEA = 0.036, SRMR = 0.041), and Harman's single-factor test did not indicate serious common method bias. Higher health literacy and self-regulated learning were associated with greater odds of low-risk rather than high-risk membership. Network analysis identified loss of control, academic worry, delayed bedtime, and academic avoidance as central or bridge nodes, whereas credibility evaluation and time management showed negative bridge expected influence.</p><p><strong>Conclusion: </strong>GenAI-related digital behavior among university students varied in ways that involved dysregulated use, academic anxiety, sleep problems, distress, and academic functioning. These findings may help universities identify students who report difficulty controlling AI use, academic worry, delayed bedtime, academic avoidance, or trouble setting limits on AI use. They also point to health literacy, self-regulation, and time management as candidate resources for future longitudinal and intervention studies.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1910408"},"PeriodicalIF":4.1,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13538084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between PM2.5 constituents and non-suicidal self-injury among Chinese adolescents: modifying role of biological rhythm. PM2.5成分与中国青少年非自杀性自伤的关系:生物节律的调节作用
IF 4.1 3区 医学
Frontiers in Public Health Pub Date : 2026-08-20 eCollection Date: 2026-01-01 DOI: 10.3389/fpubh.2026.1887542
Xiaodi Ren, Longqing Ouyang, Yang Xie, Shuqin Li, Runyu Wei, Yi Zhang, Huiqiong Xu, Hui Gao, Fangbiao Tao, Yuhui Wan, Ying Tang
{"title":"Association between PM<sub>2.5</sub> constituents and non-suicidal self-injury among Chinese adolescents: modifying role of biological rhythm.","authors":"Xiaodi Ren, Longqing Ouyang, Yang Xie, Shuqin Li, Runyu Wei, Yi Zhang, Huiqiong Xu, Hui Gao, Fangbiao Tao, Yuhui Wan, Ying Tang","doi":"10.3389/fpubh.2026.1887542","DOIUrl":"10.3389/fpubh.2026.1887542","url":null,"abstract":"<p><strong>Background: </strong>Non-suicidal self-injury (NSSI) has emerged as a growing public health concern among Chinese adolescents. Although exposure to fine particulate matter (PM<sub>2.5</sub>) has been associated with adverse mental health outcomes, the specific chemical constituents driving this association and the potential modifying role of biological rhythms remain poorly understood.</p><p><strong>Methods: </strong>A multicenter, population-based survey was conducted across 15 schools located in four provinces of China. A total of 18,398 adolescents in grades 7 through 12 completed the eligible questionnaires. NSSI behaviors were assessed using the Adolescent Non-suicidal Self-injury Assessment Questionnaire (ANSAQ). The Self-rating Questionnaire of Biological Rhythm Disorders for Adolescents (SBRDA) was used to conduct a comprehensive assessment of participants' multidimensional biological rhythms. Binary logistic regression and weighted quantile sum (WQS) regression were employed to examine the associations between PM<sub>2.5</sub> constituents and NSSI, with stratified analyses performed to explore the moderating effects of factors such as biological rhythms.</p><p><strong>Results: </strong>After adjusting for covariates, PM<sub>2.5</sub> and its constituents showed significant positive associations with NSSI risk, with black carbon exhibiting the strongest association (<i>OR</i> = 1.76, 95% <i>CI</i>: 1.60-1.94). Mixed exposure analyses consistently identified black carbon as the dominant constituent (WQS weight = 0.810; Qgcomp effect size = 0.671). Stratified analyses revealed heightened vulnerability among adolescents with disrupted biological rhythms, good family economic situations, junior high school enrollment, and heavy learning burdens. Furthermore, disruptions in activity rhythm and eating rhythm can significantly amplify the risk impact of pollutants on NSSI behaviors.</p><p><strong>Discussion: </strong>Exposure to PM<sub>2.5</sub> (particularly BC) increases adolescent NSSI risk, with factors like biological rhythm disruption potentially amplifying this effect. Integrating strategies to manage BC emissions with initiatives that encourage adolescents to maintain healthy routines, such as timely meal consumption, could synergistically lower mental health risks.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"14 ","pages":"1887542"},"PeriodicalIF":4.1,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13538845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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