Frontiers in Public Health最新文献

{"title":"Effects of privacy concerns on older adults' discontinuous usage intention: the chain mediating effect of technology anxiety and the moderating role of perceived price value.","authors":"Jing An, Kexin Wan, Ziyue Xiang, Xuanyu Zhu, Jinlong An, Yujie Yang","doi":"10.3389/fpubh.2025.1543409","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1543409","url":null,"abstract":"<p><strong>Introduction: </strong>With the continuous progress of global information and communication technology, online medical care has become a hot topic. And online health consultation platforms have also emerged and provided patients, especially the older adults, with a new way to obtain health information.</p><p><strong>Objective: </strong>To explore the impact of privacy concerns, technology anxiety, dissatisfaction, and perceived price value on older adults' discontinuous usage intention of online health consultation platforms.</p><p><strong>Methods: </strong>Using quantitative analysis method, 254 valid questionnaires were collected online with the sample of older adults aged over 50 years in China. Descriptive statistics and structural equation models were established, and hypothesis testing was carried out using SPSS software.</p><p><strong>Results: </strong>In this study, privacy concerns (<i>β</i> = 0.268, <i>p</i> < 0.001), technology anxiety (<i>β</i> = 0.256, <i>p</i> < 0.001), and dissatisfaction (<i>β</i> = 0.433, <i>p</i> < 0.001) directly affect the discontinuous usage intention of online health consultation platforms, among which technology anxiety and dissatisfaction play a mediating role (<i>p</i> < 0.01). Price value moderates the impact of privacy concerns on discontinuous usage intention. The results of this study indicate that the mental state of older adults using the online health consultation platform will significantly affect their dissatisfaction and discontinuous usage intention of the platform.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1543409"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-rated health habits, mental health, emotional intelligence, and impulsivity across the Baltic States.","authors":"Albertas Skurvydas, Dovile Valanciene, Ausra Lisinskiene, Ruta Dadeliene, Asta Sarkauskiene, Andra Fernāte, Zermena Vazne, Juris Grants, Andre Koka, Daiva Majauskiene","doi":"10.3389/fpubh.2025.1522918","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1522918","url":null,"abstract":"<p><strong>Introduction: </strong>The study aims to compare physical activity, sleep, body mass index (BMI), subjective health, stress, depression, impulsivity, and emotional intelligence across the Baltic countries while identifying key health determinants.</p><p><strong>Methods: </strong>We interviewed men and women (18-64 years) in Estonia (<i>n</i> = 1,503) Latvia (<i>n</i> = 1,563) and Lithuania (<i>n</i> = 2,358) via an online survey.</p><p><strong>Results: </strong>Obesity is most common among individuals in EE, both males and females, while the highest rates of overweight are observed in EE females and LT males. Sleep duration is comparable across the different countries, with women generally sleeping longer than men (<i>p</i> < 0.05). Sedentary behavior is shortest among LT females and LV males, although in all countries, females tend to sit more than males (<i>p</i> < 0.05). Moderate physical activity (MPA) levels are similar among males, but they are highest among EE females. In contrast, vigorous physical activity (VPA) is most prevalent in LV males and females. Emotional intelligence (EI) is lowest among LV females and EE males, while females consistently exhibit higher EI than males across all countries. Lithuanians frequently rate their health as \"excellent\" and show the lowest levels of impulsivity. Additionally, depression and stress are lowest in EE females and LV males. Estonians are more likely to eat breakfast regularly and tend to overeat less than their counterparts in LV and LT.</p><p><strong>Conclusion: </strong>Our research clearly shows that perceived health among the Baltic countries is significantly inversely related to age, perceived stress, depression, and Body Mass Index (BMI). In contrast, we found positive associations between vigorous physical activity (VPA) and emotional intelligence (EI).</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1522918"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual reality solution to promote adapted physical activity in older adults: outcomes from VR2Care project exploratory study.","authors":"Vincenzo De Luca, Malak Qbilat, Alessandra Cuomo, Antonio Bianco, Francesca Cesaroni, Chiara Lanari, Ad van Berlo, Telma Mota, Lucia Pannese, Michael Brandstötter, Matthieu Arendse, Vania Mota, Willeke van Staalduinen, Hugo Paredes, Guido Iaccarino, Maddalena Illario","doi":"10.3389/fpubh.2025.1584406","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1584406","url":null,"abstract":"<p><strong>Background: </strong>Insufficient physical activity is one of the leading risk factors for death worldwide. Regular exercise can improve physical performance and quality of life, reduce the risks of falls and depressive symptoms, and reduce the likelihood of cognitive decline in older adults. Virtual reality (VR) and serious games (SG) are promising tools to improve physical and cognitive functioning. As part of the VR2Care project activities, four pilot sites explored the capabilities of the VR environment in a remote psychomotor training with SG and a hybrid approach with local groups of older adults performing physical activity.</p><p><strong>Objective: </strong>The present study aimed to explore and measure the impact on older adults' quality of life and physical activity of using VR2Care solution and the level of usability, satisfaction and acceptance.</p><p><strong>Methods: </strong>The study is a mixed method study, using qualitative and quantitative surveys to evaluate quality of life and physical activity of older users, and usability, satisfaction and acceptance of the solution. The data collection is a mix of investigator site data entry and users' self-reported data through the solutions or through online and paper-based means. Data were collected at baseline and after a follow-up of 6 weeks. Data are expressed as mean ± standard deviation (SD) unless otherwise stated. Within the group, baseline to end of observation differences were assessed by paired sample t-test. A <i>p</i> = 0.05 was considered significant.</p><p><strong>Results: </strong>No significant improvements in quality of life and physical activity were found. Little improvement, although not significant, in physical activity was found, comparing the Total MET average value of users who participated in phase I and II, therefore using SmartAL and Rehability. Little improvement, although not significant, in physical activity applies in ≥76 population. Users' feedback on usability, satisfaction and acceptance of VR2Care is generally positive. VR2Care was appreciated mostly for its usefulness in managing physical activity and the capacity to influence the consistency of attending physical activity sessions as prescribed by doctors.</p><p><strong>Conclusion: </strong>Our results suggest that randomized controlled trial will be needed to assess correlations between specific features of the solution and health outcomes.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1584406"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Cannabis and cannabinoids in psychiatry.","authors":"Pooja R Sarkar, Mark S Gold, Kevin P Hill","doi":"10.3389/fpubh.2025.1618252","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1618252","url":null,"abstract":"","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1618252"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and preliminary validation of the nutrition literacy scale for type 2 diabetes mellitus in China-a mixed methods study.","authors":"Wenjuan Zhang, Yan Wu, Yibao Zhang, Ziyu Sun, Jiaqi Wang, Yuhong Wu","doi":"10.3389/fpubh.2025.1569675","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1569675","url":null,"abstract":"<p><strong>Background: </strong>Nutrition literacy is an important predictor of eating behavior in patients with type 2 diabetes. However, current methods lack rigorously validated tools to assess nutrient literacy in this group. Therefore, the aim of this study was to develop and validate the Nutrition Literacy Scale for patients with type 2 diabetes mellitus.</p><p><strong>Methods: </strong>This study was divided into two phases, including the generation of the items and the validation of the scales. The generation of the items was developed through a literature study, semi-structured interviews, a Delphi expert consultation, and a small-sample pre-survey. Convenience sampling method was used to select a large sample of 576 patients in Hangzhou for item analysis, reliability and validity tests.</p><p><strong>Results: </strong>The formal scale covered 4 dimensions with 31 items. The exploratory factor analysis extracted four common factors with a cumulative variance contribution of 62.725%; the results of the confirmatory factor analysis showed that the model fit was good, the content validity of the scale was 0.957. The calibration correlation validity of the newly developed scale with the Adult Nutrition Literacy Measurement Scale was 0.760. Cronbach's <i>α</i> coefficient was 0.946, and re-test reliabilitiy was 0.884.</p><p><strong>Conclusion: </strong>The nutrition literacy scale for people with type 2 diabetes has good reliability and validity and is suitable for assessing the level of nutrition literacy in relevant populations.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1569675"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weight changes among antiretroviral therapy-naïve people living with human immunodeficiency virus in Lagos, Nigeria.","authors":"Oluwatosin Olaseni Odubela, Nasheeta Peer, Nkiruka Nnonyelum Odunukwe, Adesola Zaidat Musa, Babatunde Lawal Salako, Andre Pascal Kengne","doi":"10.3389/fpubh.2025.1545676","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1545676","url":null,"abstract":"<p><strong>Introduction: </strong>The advent of antiretroviral therapy (ART) has converted HIV from a death sentence to a chronic disease. Subsequently, weight changes, including the development of overweight/obesity have been observed following ART initiation. Our study aimed to assess weight changes and the associated factors among ART-naïve people living with HIV (PLWH) following enrollment in an ART clinic in Lagos, Nigeria.</p><p><strong>Methodology: </strong>Data were collected among adult ART-naïve PLWH enrolled at a large ART clinic over 10 consecutive years. Weight changes within the first 6 months of enrolment were determined by actual and relative weight differences expressed in kilogram (kg) and percentages (%) respectively. Weight changes were classified as neutral weight change, weight gain and weight loss. Logistic regressions were applied to identify variables associated with weight changes with statistical significance set at <i>p</i> < 0.05.</p><p><strong>Results: </strong>A total of 6,737 study participants had their weights available at both visits. Most study participants were females (67.2%), employed (83.3%), married (57.1%), and had normal range body mass index (53.5%). Almost half (49.5%) of the study participants gained weight, while 25.5% recorded weight loss. Baseline variables, including viral load ≥ 100,000 copies/ml, CD4 counts ≤ 200 cells/μL, WHO clinical stages 3 and 4, male gender, presence of anaemia and tuberculosis were associated with weight gain after ART initiation.</p><p><strong>Conclusion: </strong>Considering the high proportion of participants that gained weight, this study highlights the importance of monitoring weight changes following ART initiation. This will facilitate the identification of PLWH at greater risk for cardiometabolic diseases and other weight-related health outcomes.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1545676"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the effect of social media use on medical students' academic performance: cross-sectional study from Jordan.","authors":"Hana Taha, Diana Abu-Surrah, Luna Abu-Awadh, Ameen Mahmoud, Tamara Al-Qadi, Layan Al Hamdan, Moumen Hijazi, Abdulla Al Ani, Vanja Berggren","doi":"10.3389/fpubh.2025.1551905","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1551905","url":null,"abstract":"<p><strong>Background: </strong>The use of social media in the modern world is necessary to stay equipped with the fast-paced changes of the 21st century. The integration of social media platforms into the life of medical students and their effect on their academic performance has not been studied enough.</p><p><strong>Objective: </strong>This study examines the duration of time spent on social media, the type of content medical students is exposed to, the online engagement in study groups, and the influence of the interaction between students and their professors via social media on students' academic performance.</p><p><strong>Methods: </strong>A cross-sectional study that used structured self-administered online questionnaire to assess the use of social media by a random sample of 429 medical students in Jordan. The data was analyzed using descriptive and multivariate analysis by SPSS 28.</p><p><strong>Results: </strong>Over 61.3% of participants used social media for 3 h or more per day. Instagram (48.7%) followed by Facebook (19.3%) and YouTube (11.9%) were the most utilized platforms. Entertainment content was the most pursued on social media (83.0%) followed by educational purposes (72.5%), sports (29.1%), and politics-related activities (17.9%). Approximately 64.6% of the students indicated that using social media is distracting, decreases their ability to focus (65.3%) and delays their daily tasks (61.8%). GPA was significantly associated with more time spent on social media (OR: 0.476; 95%CI: 0.278-0.813; <i>p</i> = 0.022). The negative impact of social networking on academic performance was significantly associated with GPA (OR: 2.292; 95%CI: 1.244-4.224; <i>p</i> = 0.007).</p><p><strong>Conclusion: </strong>This study provided evidence about the pattern and effect of using social media on the academic performance of medical students in Jordan. It delivered context-sensitive data for decision-making to enhance the positive use of social media by medical students. It also highlighted the importance of using appropriate online educational platforms to engage the medical students in relevant learning activities.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1551905"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional, and national analyses of the burden among adult women of breast cancer attributable to diet high in red meat from 1990 to 2021: longitudinal observational study.","authors":"Xiaoyun Ding, Zhenning Tang, Hang Ma, Can Jiang","doi":"10.3389/fpubh.2025.1580177","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1580177","url":null,"abstract":"<p><strong>Background: </strong>The association between red meat consumption and breast cancer risk has been well established; however, it is crucial to understand the temporal trends, geographical variations, and socio-demographic factors that influence this risk among women aged 25-45. Consequently, this study seeks to investigate the impact of red meat consumption on breast cancer risk among adult women for the first time.</p><p><strong>Methods: </strong>Data were extracted from the Global Burden of Disease (GBD) 2021 study to calculate age-standardized rates (ASR) for mortality and disability-adjusted life years (DALYs). Trends were assessed using estimated annual percentage change (EAPC) with linear regression analysis. Hierarchical clustering identified temporal trends, and examined the relationships between EAPC, ASR, DALYs, and the socio-demographic index (SDI).</p><p><strong>Results: </strong>Our findings indicate that breast cancer-related deaths and DALYs attributable to high red meat consumption increased globally, rising from 44,492 deaths and 1,379,721 DALYs in 1990 to 79,956 deaths and 2,407,092 DALYs in 2021. In high SDI regions, age-standardized mortality (-1.47%) and DALYs (-1.48%) rates declined, while low-middle and high-middle SDI regions showed significant increases. Low SDI regions, despite lower absolute numbers, experienced sharp relative increases in both deaths and DALYs. Additionally, a nonlinear relationship between ASR and SDI was observed, with the burden peaking in moderate SDI regions.</p><p><strong>Conclusion: </strong>This study concludes the rising global burden of breast cancer in adult women associated with high red meat consumption, with particularly pronounced impacts in low and middle SDI regions.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1580177"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12107595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The intention and influencing factors of human papillomavirus vaccination among female students in the secondary vocational schools in East China: a cross-sectional study.","authors":"Ruihua Zhang, Junhui Du, Zhixiang Zhang","doi":"10.3389/fpubh.2025.1467546","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1467546","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to explore the intention and influencing factors toward HPV vaccination among female students in secondary vocational schools in East China.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 500 female students aged 16-20 years from four secondary vocational schools in East China from September to December 2023. The information, including HPV and HPV vaccine-related knowledge questionnaire, family characteristics, attitudes toward premarital sex, information sources, and HPV vaccination or appointment status, was collected through an online questionnaire survey. According to the vaccination or appointment status, 421 participants who met the inclusion criteria were divided into two groups. The relationship between different factors and HPV vaccination intention was assessed using univariate and multivariate logistic analyses.</p><p><strong>Results: </strong>Out of 421 participants, 286 (67.9%) were in the nonappointment group, while 135 (32.1%) were in the appointment/vaccination group. There was no significant difference in HPV and HPV vaccine-related knowledge scores and attitudes toward premarital sex between the two groups (<i>p</i> > 0.05). The factors such as grade level, family characteristics (including family's residence, parents' highest education level, monthly living expenses, and only child), and information sources showed significant differences between the two groups (<i>p</i> < 0.05). After multivariate logistic regression analysis (analyzing one characteristic at a time and adjusting all other characteristics as confounders), factors such as higher grades (grade 3 [odds ratio, OR = 0.39; 95% confidence interval, CI: 0.22-0.68], grade 4 [OR = 0.03; 95% CI: 0.02-0.07]), family's residence in urban areas (OR = 1.94; 95% CI: 1.1-3.41), monthly living expenses ≥2000 yuan (OR = 2.19; 95% CI: 1.08-4.47), only child (OR = 2; 95% CI: 1.2-3.36), and information sources from family or friends (OR = 2.34; 95% CI: 1.18-4.62), were independent influencing factors of HPV vaccination intention (all <i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>The HPV vaccination policy of the local government significantly impacts accination intention. Meanwhile, family factors are independent influencing factors on HPV vaccination intention. When promoting HPV vaccination, secondary vocational schools in East China should focus on senior female students from rural areas, low-income families, and families with multiple children.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1467546"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness analysis of herpes zoster vaccination for adults aged 50 years in Zhejiang province, China.","authors":"Fuxing Chen, Linglin Ding, Yu Hu","doi":"10.3389/fpubh.2025.1401930","DOIUrl":"https://doi.org/10.3389/fpubh.2025.1401930","url":null,"abstract":"<p><strong>Objective: </strong>Live-attenuated zoster vaccine (LZV) and adjuvanted recombinant zoster vaccine (RZV) have been approved for use in China. This study aimed to evaluate and compare the cost-effectiveness of these two herpes zoster (HZ) vaccination strategies in a birth cohort of individuals aged 50 years.</p><p><strong>Methods: </strong>The cost-effectiveness of RZV and LZV was compared to no vaccination strategy using a lifetime Markov model from a societal perspective. Model parameters were obtained from up-to-date published literature and statistical data. The costs associated with vaccination and medical treatment, quality-adjusted life years (QALYs), the number of herpes zoster and related complication cases averted, and the incremental cost-effectiveness ratio (ICER) were calculated. Sensitivity analyses were performed to assess the robustness of the results.</p><p><strong>Results: </strong>Compared to the no-vaccination strategy, the RZV strategy was estimated to prevent 4,126 HZ cases and 772 postherpetic neuralgia (PHN) cases, while the LZV strategy was estimated to avert 2,355 HZ cases and 467 PHN cases. The ICER was estimated at 711.46 US $/QALY and 914.62 US $/QALY for the RZV and LZV strategies, respectively.</p><p><strong>Conclusion: </strong>HZ vaccination could provide significant health benefits at a reasonable cost. RZV was predicted to be more cost-effective than LZV.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1401930"},"PeriodicalIF":3.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144156637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}