Frontiers in Public Health最新文献

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Impact of accelerated review policy on portfolio planning of vaccine companies.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1339141
Guicui Liu, Zhe Huang
{"title":"Impact of accelerated review policy on portfolio planning of vaccine companies.","authors":"Guicui Liu, Zhe Huang","doi":"10.3389/fpubh.2024.1339141","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1339141","url":null,"abstract":"<p><strong>Background: </strong>With the introduction of the accelerated drug review policy in China, the clinical research and development time and the review and approval time of drugs have been shortened accordingly. Especially under the influence of the COVID-19 pandemic, the vaccine formulations released through the accelerated review policy are springing up, and the question of how the accelerated review policy affects the investment portfolio of vaccine enterprises has also attracted more and more attention.</p><p><strong>Aims and methods: </strong>The article uses mixed-integer linear programming to develop a new model on portfolio planning for vaccine companies based on the accelerated review policy context. The model is constructed using the Gurobi extension class of .NET, and the investment decision is made and simulated by the Gurobi solver to investigate the portfolio planning decision of a vaccine company maximizing the net present value of its vaccine production portfolio with the increase of available capital over a 20-year time horizon.</p><p><strong>Results: </strong>The NPV under the accelerated review policy is significantly higher than the net present value under the standard review policy when the available capital exceeds RMB 900 million. And the difference between the two of them peaks at RMB 1.87 billion when the available capital is RMB 1.9 billion; break-even occurs about 1.3 years earlier in the accelerated review policy than in the standard review; and when the available capital is the same, firms in the accelerated review policy choose to produce four products earlier and make the decision to invest in facility construction earlier; scenarios in the accelerated review policy are not as sensitive to changes in model parameters as they are in the standard review.</p><p><strong>Conclusion: </strong>The accelerated review policy is effective in providing incentives for commercialisation. The results of this study will provide an effective reference for vaccine companies to make scientific portfolio planning under the accelerated review policy.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1339141"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between phenotypic age and mortality risk in individuals with obesity: a retrospective cohort study.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1505066
Yingxuan Huang, Apei Zhou, Yisen Huang, Yubin Wang, Xiaobo Liu, Xiaoqiang Liu
{"title":"Association between phenotypic age and mortality risk in individuals with obesity: a retrospective cohort study.","authors":"Yingxuan Huang, Apei Zhou, Yisen Huang, Yubin Wang, Xiaobo Liu, Xiaoqiang Liu","doi":"10.3389/fpubh.2024.1505066","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1505066","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the association between phenotypic age acceleration (PAA) and all-cause and cause-specific mortality in obese individuals.</p><p><strong>Methods: </strong>Data were drawn from the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2018, including 9,925 obese adults (BMI ≥ 30 kg/m<sup>2</sup>). PAA, defined as phenotypic age exceeding chronological age, was assessed using clinical biomarkers. Kaplan-Meier survival analysis and Cox proportional hazards models were used to assess the relationship between PAA and all-cause, cardiovascular, and cancer mortality, adjusting for covariates such as age, gender, race, lifestyle, and health status. Subgroup and sensitivity analyses were performed to ensure the robustness of the findings.</p><p><strong>Results: </strong>During a median follow-up of 10.6 years, 1,537 deaths were recorded, including 419 from cardiovascular disease and 357 from cancer. PAA was significantly associated with all-cause mortality (HR = 1.84, 95% CI: 1.64-2.06), cardiovascular mortality (HR = 1.86, 95% CI: 1.50-2.31), and cancer mortality (HR = 1.47, 95% CI: 1.17-1.85). These associations remained significant after adjusting for multiple variables, and sensitivity analyses confirmed the robustness of the results.</p><p><strong>Conclusion: </strong>PAA is an independent predictor of all-cause, cardiovascular, and cancer mortality in obese individuals. This study highlights the importance of PAA in mortality risk assessment and health management in the obese population.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1505066"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interventions to support the psychological empowerment of nurses: a scoping review.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1427234
Liebin Huang, Ming Liu, Xin Wang, Meihua Hsu
{"title":"Interventions to support the psychological empowerment of nurses: a scoping review.","authors":"Liebin Huang, Ming Liu, Xin Wang, Meihua Hsu","doi":"10.3389/fpubh.2024.1427234","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1427234","url":null,"abstract":"<p><strong>Background: </strong>Establishing an empowering work environment is significantly contributing to nurse's job satisfaction, performance, retention, and organizational success. This study aimed to conduct a scoping review to chart and synthesize current research on interventions to support nurses' psychological empowerment.</p><p><strong>Methods: </strong>Ten databases were searched, including PubMed/Medline, Web of Science, Scopus, Embase, EBSCOhost, Cochrane Library, CNKI, Wanfang, VIP, and OpenGrey, following the Joanna Briggs Institute's methodology for scoping reviews. The search encompassed literature from its inception to 5 September 2024. The selection of studies followed predetermined inclusion and exclusion criteria. A manualized systematic quality assessment method was applied to the included studies, and the extracted data were charted using a series of tables.</p><p><strong>Results: </strong>Eleven studies were included. Seven studies reported the theoretical framework used. The interventions are all educational and are divided into two main sections: theoretical learning and applied practice. The duration of the interventions spanned a wide range of hours. The intervention format was based on offline training. The participants included both nurse managers and nurses. The evaluation measures were mostly multiple time points using the Spreitzer Psychological Empowerment Instrument. The interventions were generally effective, although some studies reported different results.</p><p><strong>Conclusion: </strong>Research on psychological empowerment interventions for nurses is still in the developmental phase, with preliminary evidence validating their positive effects. Future research should focus on conducting randomized controlled studies with larger sample sizes, selecting appropriate theoretical frameworks to design interventions, enriching the content and form of interventions, and strengthening evaluation measures to improve the quality of psychological empowerment interventions for nurses.</p><p><strong>Systematic review registration: </strong>OSF, https://doi.org/10.17605/OSF.IO/W7ZG6.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1427234"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition literacy profile among adolescents in Kuwait: a cross-sectional study.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1453484
Anwar H AlBaloul, Maraheb M AlKhalidi, Haya AlAjmi
{"title":"Nutrition literacy profile among adolescents in Kuwait: a cross-sectional study.","authors":"Anwar H AlBaloul, Maraheb M AlKhalidi, Haya AlAjmi","doi":"10.3389/fpubh.2024.1453484","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1453484","url":null,"abstract":"<p><strong>Background: </strong>Adolescent nutrition literacy and knowledge are associated with nutrient intake and obesity. With the rising prevalence of obesity in Kuwait, limited studies have assessed nutrition literacy among Kuwaiti adolescents. Therefore, this study aims to assess nutrition literacy among Kuwaiti adolescents and examine factors associated with nutrition literacy, such as body mass index (BMI) and dietary intake.</p><p><strong>Methods: </strong>A school-based cross-sectional study was conducted in public schools across Kuwait, enrolling a convenience sample of 375 adolescents (mean age = 15.6 years, 53.1% female participants). A self-administered questionnaire was used to collect relevant data. The Nutrition Literacy Assessment Instrument (NLit) score was used to assess nutrition knowledge and skills in making food choices.</p><p><strong>Results: </strong>The median NLit score among adolescents was 29 (IQR = 6). A large percentage (72.5%) of Kuwaiti adolescents demonstrated adequate overall nutrition literacy and scored adequately in the majority of NLit subscales. However, the majority of adolescents (73.3%) demonstrated inadequate nutrition literacy in understanding food labels. Predictors of NLit included BMI, place of residence, and smoking status. Moreover, the NLit score was negatively associated with the intake of sugar-sweetened beverages.</p><p><strong>Conclusion: </strong>This study's findings may inform future research aimed at designing effective nutrition literacy interventions to enhance food choices among adolescents in Kuwait. The results of this study may also provide insights for policymakers and public health professionals to tailor food and nutrition programs to address the decline in food literacy skills and combat obesity.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1453484"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Examining upstream to understand downstream: use of telehealth and other health equity measures for addressing health disparities.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1529825
Gulzar H Shah, Kristie Cason Waterfield, Tran Nguyen, Sripriya Rajamani
{"title":"Editorial: Examining upstream to understand downstream: use of telehealth and other health equity measures for addressing health disparities.","authors":"Gulzar H Shah, Kristie Cason Waterfield, Tran Nguyen, Sripriya Rajamani","doi":"10.3389/fpubh.2024.1529825","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1529825","url":null,"abstract":"","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1529825"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A large-scale screening of hepatitis C among men who have sex with men in the community using saliva point-of-care testing.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1478195
Sonia Albertos, Francesc X Majo, Rafael Esteban, Joan Colom, María Buti
{"title":"A large-scale screening of hepatitis C among men who have sex with men in the community using saliva point-of-care testing.","authors":"Sonia Albertos, Francesc X Majo, Rafael Esteban, Joan Colom, María Buti","doi":"10.3389/fpubh.2024.1478195","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1478195","url":null,"abstract":"<p><strong>Aim: </strong>To assess the feasibility and acceptability of massive hepatitis C virus (HCV) testing in point of care on the street using quick tests, determine the characteristics of the population included, and the prevalence of HCV infection in this population.</p><p><strong>Methods: </strong>Cross-sectional community-based study including adult men who have sex with men (MSM) who attended the three most important LGTB+ events in Sitges (Catalonia, Spain) in 2022. Points of care were set up on tents on the street and attendees were offered voluntary anti-HCV antibody self-testing. Participants were informed of the study, provided consent, completed the test for identification of risk practices (TIRP), and took the test with the OraQuick® HCV test on a saliva sample (sensitivity: 97.8% [95% confidence interval (CI), 93.2-99.4%] and specificity: 100% [95% CI, 98.4-100%]; gold standard: IgG antibody test for HCV by immunoassay [serum]); participants with positive results were offered HCV virus testing with the Xpert HCV Fingerstick® on a blood drop.</p><p><strong>Results: </strong>A total of 1249 adults participated in the large-scale screening, of which 1197 (95.8%) were identified as MSM. The screening time was 39 participants/h. Four (0.32%) participants had positive anti-HCV results, all with undetectable HCV RNA levels. Participants' median (IQR) age was 44 (35, 54) years; most were Europeans, and 13% reported being unaware of their serological HCV status. The mean (SD) TIRP score was 1.40 (1.44) (<i>n</i> = 1062), with 67.41% reporting some risk, and the self-perceived sexually transmitted disease score was 3.0 (2.82) (<i>n</i> = 969).</p><p><strong>Conclusion: </strong>The point-of-care strategy on the street using a quick oral self-test at massive MSM events is feasible, well-accepted, and quick, and may be a useful strategy to reach other populations at risk of HCV infection.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1478195"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Burden of melanoma in China and its provinces from 1990 to 2021: an analysis for the Global Burden of Disease Study 2021.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1486617
Lingling Yu, Fanshu Yan, Jinlei Qi, Lijun Wang, Maigeng Zhou, Peng Yin
{"title":"Burden of melanoma in China and its provinces from 1990 to 2021: an analysis for the Global Burden of Disease Study 2021.","authors":"Lingling Yu, Fanshu Yan, Jinlei Qi, Lijun Wang, Maigeng Zhou, Peng Yin","doi":"10.3389/fpubh.2024.1486617","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1486617","url":null,"abstract":"<p><strong>Background: </strong>The incidence of melanoma in China has been increasing over the past few decades. This study aimed to investigate the burden of melanoma at both national and subnational level in China, where the population is rapidly aging.</p><p><strong>Methods: </strong>The annual melanoma data from 1990 to 2021 was collected from the Global Burden of Disease (GBD) 2021 China subnational study. Number of cases and age-standardized rates were estimated for incidence, mortality, prevalence, disability-adjusted life-years (DALYs) of melanoma by age and sex at subnational level with 33 province-level administrative units. Joinpoint regression model was used to evaluate the trends in disease burdens attributable to melanoma across time. A decomposition method was used to attribute changes in total deaths and DALYs to three explanatory components: population growth, population aging, and change of age-specific rates.</p><p><strong>Results: </strong>Over the past 30 years, the age-standardized incidence rate (ASIR) of melanoma in China has shown an upward trend. The ASIR of melanoma in 2021 was 0.7 per 100,000 (95%UI 0.4-0.9), representing an increase of 89.2% (95% UI: 14.7-157.9%) from 1990. Among younger adults aged <60 years, melanoma was more common in men, whereas among older adults who were aged >60 years, it was more common in women. The ASIR was higher in the coastal provinces in 2021 and the age-standardized rates (ASR) of DALYs was generally higher in the western provinces. Total numbers of death and DALYs of melanoma increased over the study period, mainly driven by population aging in China.</p><p><strong>Conclusion: </strong>China has experienced a substantial increase in the burden of melanoma from 1990 to 2021. It is beneficial to develop more targeted strategies for older adults populations, especially for women, to reduce the melanoma burden throughout China, particularly in some coastal and western provinces.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1486617"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between ethylene oxide exposure and chronic bronchitis: results from the NHANES 2013-2018.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1424555
Yan Li, Hui Wang, Xiaoqing Bi, Guowei Zhao
{"title":"Associations between ethylene oxide exposure and chronic bronchitis: results from the NHANES 2013-2018.","authors":"Yan Li, Hui Wang, Xiaoqing Bi, Guowei Zhao","doi":"10.3389/fpubh.2024.1424555","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1424555","url":null,"abstract":"<p><strong>Introduction: </strong>Ethylene oxide (EtO) is a reactive gas commonly used in the production of various chemical compounds. Research has linked EtO exposure to respiratory conditions, including chronic obstructive pulmonary disease (COPD) and asthma. However, its potential effects on chronic bronchitis (CB) remain unclear, highlighting the need for further study to understand its role in respiratory health.</p><p><strong>Methods: </strong>Our study investigated data from 5,044 NHANES participants between 2013 and 2018 across three 2-year survey cycles. The relationship between HbEtO and CB was examined using weighted logistic regression, with HbEtO quartiles analyzed to assess the trend. A smoothed curve was fitted to verify the relationship between HbEtO and CB. Additionally, sensitivity analyses were conducted to assess the robustness of our results, while subgroup analyses explored potential effect modifiers of the HbEtO-CB association.</p><p><strong>Results: </strong>Compared with patients without CB, patients with CB had elevated HbEtO levels. Specifically, natural Log<sub>2</sub>HbEtO levels were linked to a greater prevalence of CB in a fully adjusted model (OR = 1.243, 95% CI: 1.143-1.352). Analysis of Log<sub>2</sub>HbEtO quartiles showed a significant trend in Q4 compared with Q1 (<i>p</i> for trend < 0.001). The fitted smoothed curve indicated a U-shaped nonlinear association, with saturation and threshold analysis revealing an inflection point at Log<sub>2</sub>HbEtO = 4.87. Sensitivity analyses confirmed the robustness of these findings, and subgroup analyses identified consistent associations across various groups.</p><p><strong>Conclusion: </strong>Our study found a significant association between EtO exposure and the occurrence of CB. Given the health risks linked to EtO exposure, implementing effective control measures is essential. Such actions could help lower CB prevalence and enhance respiratory health in vulnerable populations.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1424555"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diarrhea and associated factors among under-five children in open defecation free and open defecation rural households of Degem district, Oromia, Ethiopia.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1480949
Demelash Dereje, Dejene Hailu, Sisay Abebe Debela, Tamiru Yazew, Fikadu Tolesa, Bogalu Abebe
{"title":"Diarrhea and associated factors among under-five children in open defecation free and open defecation rural households of Degem district, Oromia, Ethiopia.","authors":"Demelash Dereje, Dejene Hailu, Sisay Abebe Debela, Tamiru Yazew, Fikadu Tolesa, Bogalu Abebe","doi":"10.3389/fpubh.2024.1480949","DOIUrl":"https://doi.org/10.3389/fpubh.2024.1480949","url":null,"abstract":"<p><strong>Introduction: </strong>Diarrheal diseases are the top cause of preventable death, particularly among children under the age of five in developing countries like Ethiopia. Despite the national level of latrine coverage being 61%, diarrhea is responsible for the deaths of half a million children under 5 years annually. Therefore, this study aimed to assess diarrhea and its associated factors among children in open defecation free (ODF) and open defecation (OD) households of Degem district, Oromia, Ethiopia.</p><p><strong>Methods: </strong>A comparative cross-sectional study was conducted within the community, involving 398 participants (200 from open defecation free [ODF] and 198 from open defecation [ODF] households). The selection of study participants from OD and ODF households was done using a multistage sampling approach. Data input was carried out using Epi Data 3.1, while data analysis would be performed using Statistical Package for Social Sciences (SPSS) version 26 software, employing appropriate testing methods. Statistical significance and the strength of relationships were assessed using odds ratios with a 95% confidence interval.</p><p><strong>Results: </strong>The prevalence of diarrhea among children in open defecation free and open defecation households was 26 and 38%, respectively. Factors such as children who were not vaccinated for rotavirus, mothers or caregivers did not have diarrhea, mothers or caregivers did not wash their hands at critical times, and individuals with poor latrine utilization were significantly associated with diarrhea among children in ODF households. On the other hand, children who were not vaccinated for rotavirus, not received vitamin A supplementation, mothers or caregivers did not wash their hands at critical times, children lacking access to latrines and children whose their families practice open field solid waste disposal were significantly associated with diarrhea among children in open defecation free households.</p><p><strong>Conclusion: </strong>The study results indicated that the prevalence of diarrhea among children under five in open defecation areas was notably higher compared to those residing in open defecation free areas. Consequently, it is imperative for all responsible bodies to focus on evidence-based strategies to combat childhood diarrhea and to ensure child health status.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"12 ","pages":"1480949"},"PeriodicalIF":3.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measurement and decomposition of education-related inequality in exclusive breastfeeding practice among Ethiopian mothers: applying Wagstaff decomposition analysis.
IF 3 3区 医学
Frontiers in Public Health Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.3389/fpubh.2024.1407210
Anteneh Mengist Dessie, Melkamu Aderajew Zemene, Asaye Alamneh Gebeyehu, Denekew Tenaw Anley, Rahel Mulatie Anteneh, Natnael Moges, Ermias Sisay Chanie, Sintayehu Simie Tsega, Melaku Ashagrie Belete, Ermiyas Alemayehu, Natnael Kebede
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