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Fundamental Toxicological Sciences最新文献

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Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals 定量构效关系和一类方法支持人用药物的藻类毒性评价
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/fts.8.195
Takashi Yamada, T. Kawamura, Taeko Maruyama, Masayuki Kurimoto, Hiroshi Yamamoto, N. Katsutani, A. Hirose
{"title":"Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals","authors":"Takashi Yamada, T. Kawamura, Taeko Maruyama, Masayuki Kurimoto, Hiroshi Yamamoto, N. Katsutani, A. Hirose","doi":"10.2131/fts.8.195","DOIUrl":"https://doi.org/10.2131/fts.8.195","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78820622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells 在培养的牛主动脉内皮细胞中，核仁蛋白积极调节细胞的自发增殖，但不参与铅对细胞增殖的抑制
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.233
Tsutomu Takahashi, Yuka Takagi, Y. Honma, Y. Shinoda, Y. Tsuneoka, Takato Hara, C. Yamamoto, T. Kaji, Y. Fujiwara
{"title":"Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells","authors":"Tsutomu Takahashi, Yuka Takagi, Y. Honma, Y. Shinoda, Y. Tsuneoka, Takato Hara, C. Yamamoto, T. Kaji, Y. Fujiwara","doi":"10.2131/fts.7.233","DOIUrl":"https://doi.org/10.2131/fts.7.233","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"9 1","pages":"233-239"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74862278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia 印度尼西亚手工小规模金矿地区从大米中摄取汞与人类健康风险
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.215
Randy Novirsa, Q. Dinh, Huiho Jeong, Sylvester Addai-Arhin, W. Nugraha, Nana Hirota, B. Wispriyono, Y. Ishibashi, K. Arizono
{"title":"The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia","authors":"Randy Novirsa, Q. Dinh, Huiho Jeong, Sylvester Addai-Arhin, W. Nugraha, Nana Hirota, B. Wispriyono, Y. Ishibashi, K. Arizono","doi":"10.2131/fts.7.215","DOIUrl":"https://doi.org/10.2131/fts.7.215","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"18 1","pages":"215-225"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72881324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Postnatal wheel running mitigates endocrine disruption of mammary gland development in mice 产后跑轮可减轻小鼠乳腺发育的内分泌干扰
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.189
Emily E. Schmitt, W. Porter, J. T. Lightfoot
{"title":"Postnatal wheel running mitigates endocrine disruption of mammary gland development in mice","authors":"Emily E. Schmitt, W. Porter, J. T. Lightfoot","doi":"10.2131/fts.7.189","DOIUrl":"https://doi.org/10.2131/fts.7.189","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"32 1","pages":"189-199"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86959969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of measuring long bone length in toxicity studies: results of a 14-day repeated dose oral toxicity study of dexamethasone in young, periadolescent and adult rats 测量长骨长度在毒性研究中的效用:对年轻、青春期和成年大鼠进行的14天重复剂量口服地塞米松毒性研究的结果
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.85
Chihiro Noguchi, Satoshi Tsuji, Y. Nakanishi, M. Sasaki
{"title":"Utility of measuring long bone length in toxicity studies: results of a 14-day repeated dose oral toxicity study of dexamethasone in young, periadolescent and adult rats","authors":"Chihiro Noguchi, Satoshi Tsuji, Y. Nakanishi, M. Sasaki","doi":"10.2131/fts.7.85","DOIUrl":"https://doi.org/10.2131/fts.7.85","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"4 1","pages":"85-96"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84969745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats 一氧化氮合酶抑制剂L-NAME对妊娠中后期大鼠蜕膜细胞增殖的抑制作用
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.287
Wataru Ishikawa, Shugo Kazama, Takehito Suzuki, Rei Yamana, Y. Miyazaki, Kazuaki Tanaka, M. Usami, T. Takizawa
{"title":"Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats","authors":"Wataru Ishikawa, Shugo Kazama, Takehito Suzuki, Rei Yamana, Y. Miyazaki, Kazuaki Tanaka, M. Usami, T. Takizawa","doi":"10.2131/fts.7.287","DOIUrl":"https://doi.org/10.2131/fts.7.287","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"1 1","pages":"287-289"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88652035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells 甲状腺毒性和肝毒性橡胶抗氧化剂2-巯基苯并咪唑及其4-或5-甲基衍生物对兔角膜细胞的体外细胞毒性
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.249
Y. Kuroda, A. Miyajima, Kazue Sakemi-Hoshikawa, M. Usami, K. Mitsunaga, Y. Ohno, M. Sunouchi
{"title":"In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells","authors":"Y. Kuroda, A. Miyajima, Kazue Sakemi-Hoshikawa, M. Usami, K. Mitsunaga, Y. Ohno, M. Sunouchi","doi":"10.2131/fts.7.249","DOIUrl":"https://doi.org/10.2131/fts.7.249","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"238 1","pages":"249-252"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74655094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex differences in the effects of high-fat diet on mouse sciatic nerves 高脂肪饮食对小鼠坐骨神经影响的性别差异
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.133
M. Ogawa, Takahiro Kimura, Y. Tanetani, Masami Hori, Takahiro Kyoya, M. Terada
{"title":"Sex differences in the effects of high-fat diet on mouse sciatic nerves","authors":"M. Ogawa, Takahiro Kimura, Y. Tanetani, Masami Hori, Takahiro Kyoya, M. Terada","doi":"10.2131/fts.7.133","DOIUrl":"https://doi.org/10.2131/fts.7.133","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"67 1","pages":"133-139"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84912002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of HepaRG cells in the mitochondrial function assay for the estimation of potential risk of idiosyncratic drug-induced liver injury HepaRG细胞在线粒体功能测定中用于评估特异性药物性肝损伤潜在风险的有效性
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.153
Keisuke Goda, T. Masuyama
{"title":"Usefulness of HepaRG cells in the mitochondrial function assay for the estimation of potential risk of idiosyncratic drug-induced liver injury","authors":"Keisuke Goda, T. Masuyama","doi":"10.2131/fts.7.153","DOIUrl":"https://doi.org/10.2131/fts.7.153","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"48 1","pages":"153-160"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90620235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats 自发性糖尿病Torii-Leprfa (SDT脂肪)大鼠与Sprague-Dawley大鼠辛伐他汀治疗后肝脏变化的比较
Fundamental Toxicological Sciences Pub Date : 2020-01-01 DOI: 10.2131/fts.7.41
Tadakazu Takahashi, Yusuke Suzuki, Naohito Yamada, K. Toyoda, Keisuke Goda, Katsunori Ryoke, Chizuru Matsuura, Akio Kobayashi, S. Sugai, K. Shimoi
{"title":"Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats","authors":"Tadakazu Takahashi, Yusuke Suzuki, Naohito Yamada, K. Toyoda, Keisuke Goda, Katsunori Ryoke, Chizuru Matsuura, Akio Kobayashi, S. Sugai, K. Shimoi","doi":"10.2131/fts.7.41","DOIUrl":"https://doi.org/10.2131/fts.7.41","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"10 1","pages":"41-54"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86704196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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