发布求助
文献互助 智能选刊 最新文献

Fundamental Toxicological Sciences最新文献

筛选
英文 中文
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice 多壁碳纳米管(MWCNT)悬浮液对小鼠呼吸道合胞病毒(RSV)感染的影响
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/fts.8.215
Seiko Hashiguchi, A. Miyauchi, Keiji Komemoto, Tomoyuki Ueda, Kenji Tokuda, A. Hirose, H. Yoshida, T. Akashi, M. Kurokawa, W. Watanabe
{"title":"Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice","authors":"Seiko Hashiguchi, A. Miyauchi, Keiji Komemoto, Tomoyuki Ueda, Kenji Tokuda, A. Hirose, H. Yoshida, T. Akashi, M. Kurokawa, W. Watanabe","doi":"10.2131/fts.8.215","DOIUrl":"https://doi.org/10.2131/fts.8.215","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85220753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity 氧化锌纳米颗粒在THP-1细胞中免疫调节活性的效力转移与细胞毒性有关
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/fts.8.205
A. Miyajima, T. Kawakami, K. Komoriya, Reiko Kato, M. Usami, K. Isama
{"title":"Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity","authors":"A. Miyajima, T. Kawakami, K. Komoriya, Reiko Kato, M. Usami, K. Isama","doi":"10.2131/fts.8.205","DOIUrl":"https://doi.org/10.2131/fts.8.205","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84213813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-dose ionizing radiation suppresses the apoptosis-induced by serum-removal culture 低剂量电离辐射抑制血清去除培养诱导的细胞凋亡
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/fts.8.249
Yuki Nakamura, Shinsuke Katoh, Junya Kobayashi, T. Umeda, Yoshiko Kobayashi, S. Numazawa
{"title":"Low-dose ionizing radiation suppresses the apoptosis-induced by serum-removal culture","authors":"Yuki Nakamura, Shinsuke Katoh, Junya Kobayashi, T. Umeda, Yoshiko Kobayashi, S. Numazawa","doi":"10.2131/fts.8.249","DOIUrl":"https://doi.org/10.2131/fts.8.249","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81777380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of long-term ingestion of D-allulose in hypercholesterolemia patients under statin therapy 长期摄入D-allulose对接受他汀类药物治疗的高胆固醇血症患者的影响
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/FTS.8.23
Misuzu Tanaka, Akane Kanasaki, Noriko Hayashi, T. Iida, K. Murao
{"title":"The influence of long-term ingestion of D-allulose in hypercholesterolemia patients under statin therapy","authors":"Misuzu Tanaka, Akane Kanasaki, Noriko Hayashi, T. Iida, K. Murao","doi":"10.2131/FTS.8.23","DOIUrl":"https://doi.org/10.2131/FTS.8.23","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"58 1","pages":"23-31"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83948584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15 瓦阿巴宁是强心性类固醇瓦阿班的一种苷元，作为LXR配体发挥作用，但通过诱导kr<s:1> ppel样因子15来避免SREBP-1的升高
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/FTS.8.17
T. Fujino, Kouta Sugizaki, Saki Ohkawa, S. Fujikawa, Toshiyuki Oshima, M. Hayakawa
{"title":"Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15","authors":"T. Fujino, Kouta Sugizaki, Saki Ohkawa, S. Fujikawa, Toshiyuki Oshima, M. Hayakawa","doi":"10.2131/FTS.8.17","DOIUrl":"https://doi.org/10.2131/FTS.8.17","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"8 1","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87671052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of an inhalation exposure system of a pressurized metered-dose inhaler (pMDI) formulation for small experimental animals 小型实验动物加压计量吸入器(pMDI)配方吸入暴露系统的研制
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/fts.8.169
Y. Taquahashi, Hirokatsu Saito, M. Kuwagata, S. Kitajima
{"title":"Development of an inhalation exposure system of a pressurized metered-dose inhaler (pMDI) formulation for small experimental animals","authors":"Y. Taquahashi, Hirokatsu Saito, M. Kuwagata, S. Kitajima","doi":"10.2131/fts.8.169","DOIUrl":"https://doi.org/10.2131/fts.8.169","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78668221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells 濑户内海(Setonaikai)养殖的叶藻(Neopyropia yezoensis)乙醇提取物对包括内分泌治疗耐药乳腺癌细胞在内的10种人类癌细胞活力的影响
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/fts.8.75
Shuso Takeda, Masayo Hirao-Suzuki, Y. Yamagishi, Takahiro Sugihara, Masataka Kaneko, G. Sakai, Tetsuya Nakamura, Yuhzo Hieda, M. Takiguchi, Masahiro Okada, N. Sugihara
{"title":"Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells","authors":"Shuso Takeda, Masayo Hirao-Suzuki, Y. Yamagishi, Takahiro Sugihara, Masataka Kaneko, G. Sakai, Tetsuya Nakamura, Yuhzo Hieda, M. Takiguchi, Masahiro Okada, N. Sugihara","doi":"10.2131/fts.8.75","DOIUrl":"https://doi.org/10.2131/fts.8.75","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89946550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity 沙利度胺电穿孔水稻胚胎的发育毒性评价
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/fts.8.189
Yuki Nishiyama, Masaya Uchida, Akinori Terada, S. Kono, H. Ishibashi, K. Arizono, N. Tominaga
{"title":"Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity","authors":"Yuki Nishiyama, Masaya Uchida, Akinori Terada, S. Kono, H. Ishibashi, K. Arizono, N. Tominaga","doi":"10.2131/fts.8.189","DOIUrl":"https://doi.org/10.2131/fts.8.189","url":null,"abstract":"The evaluation of developmental toxicity requires new methods that provide an alternative to animal use. In this study, we evaluated the effects of thalidomide exposure [upon nanosecond pulsed electric field (nsPEF) treatment] on the embryonic development of, teratogenic effects in, and gene expression levels in medaka embryos, to determine whether the adverse effects of thalidomide can be detected using medaka. Incorporation of thalidomide into medaka embryos led to malformations in individuals. The results obtained by microinjecting thalidomide into zebrafish embryos could be reproduced by medaka embryo electroporation. Furthermore, the teratogenic mechanism of thalidomide was confirmed at the genetic level. Medaka eggs, in addition to zebrafish, can be used to assess the effects of thalidomide. As the nsPEF method can efficiently incorporate of test chemicals into medaka eggs, it is suggested to have great potential for use as a high-throughput animal alternative evaluation system.","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72701224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Acrylamide in dog food 狗粮中含有丙烯酰胺
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/FTS.8.49
K. Sugita, Junpei Yamamoto, Kimika Kaneshima, Chika Kitaoka-Saito, M. Sekimoto, O. Endo, Y. Takagi, Y. Kato-Yoshinaga
{"title":"Acrylamide in dog food","authors":"K. Sugita, Junpei Yamamoto, Kimika Kaneshima, Chika Kitaoka-Saito, M. Sekimoto, O. Endo, Y. Takagi, Y. Kato-Yoshinaga","doi":"10.2131/FTS.8.49","DOIUrl":"https://doi.org/10.2131/FTS.8.49","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"40 3","pages":"49-52"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72573790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals 定量构效关系和一类方法支持人用药物的藻类毒性评价
Fundamental Toxicological Sciences Pub Date : 2021-01-01 DOI: 10.2131/fts.8.195
Takashi Yamada, T. Kawamura, Taeko Maruyama, Masayuki Kurimoto, Hiroshi Yamamoto, N. Katsutani, A. Hirose
{"title":"Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals","authors":"Takashi Yamada, T. Kawamura, Taeko Maruyama, Masayuki Kurimoto, Hiroshi Yamamoto, N. Katsutani, A. Hirose","doi":"10.2131/fts.8.195","DOIUrl":"https://doi.org/10.2131/fts.8.195","url":null,"abstract":"","PeriodicalId":12489,"journal":{"name":"Fundamental Toxicological Sciences","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78820622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信