G3: Genes|Genomes|Genetics最新文献_第6页

Identifying the sex chromosome and sex determination genes in the cattle tick, Rhipicephalus (Boophilus) microplus. 鉴定牛蜱 Rhipicephalus (Boophilus) microplus 的性染色体和性别决定基因。

IF 2.1 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-30 DOI: 10.1093/g3journal/jkae234

Jason P Tidwell, Kylie G Bendele, Deanna Bodine, V Renee Holmes, J Spencer Johnston, Perot Saelao, Kimberly H Lohmeyer, Pete D Teel, Aaron M Tarone

{"title":"Identifying the sex chromosome and sex determination genes in the cattle tick, Rhipicephalus (Boophilus) microplus.","authors":"Jason P Tidwell, Kylie G Bendele, Deanna Bodine, V Renee Holmes, J Spencer Johnston, Perot Saelao, Kimberly H Lohmeyer, Pete D Teel, Aaron M Tarone","doi":"10.1093/g3journal/jkae234","DOIUrl":"https://doi.org/10.1093/g3journal/jkae234","url":null,"abstract":"Rhipicephalus (Boophilus) microplus is globally one of the most economically important ectoparasites of cattle costing the agriculture industry billions of dollars annually. Resistance to chemical control measures has prompted the development of novel methods of control. Recent advancements in genetic control measures for human and other animal vectors have utilized sex determination research to manipulate sex ratios, which have shown promising results in mosquitoes namely Aedes aegypti and Anopheles stephensi. Here, we use R. (B.) microplus as a model to provide foundational research to allow similar avenues of investigation in ticks using R. (B.) microplus as a model. Karyotypes for R. (B.) microplus show an XX:XO sex determining system with the largest chromosome being the sex chromosome. Using flow cytometric methods, the size of the sex chromosome was estimated at 526.91 Mb. All measures to identify the sex chromosome within the cattle tick genome assembly associated sex chromosomal characteristics to two chromosomes. This discrepancy between the assembly and karyotypes of the tick led to generating a new genome assembly with a single adult male specimen. The two chromosomes in question aligned with a single scaffold within the new genome that had a length of 513.29 Mb and was the first time the sex chromosome was identified in an Ixodid genome assembly.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new high-quality genome assembly and annotation for the threatened Florida Scrub-Jay (Aphelocoma coerulescens). 为濒危的佛罗里达鸦雀（Aphelocoma coerulescens）进行新的高质量基因组组装和注释。

IF 2.1 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-27 DOI: 10.1093/g3journal/jkae232

Faye G Romero, Felix E G Beaudry, Eyvind Hovmand Warner, Tram N Nguyen, John W Fitzpatrick, Nancy Chen

{"title":"A new high-quality genome assembly and annotation for the threatened Florida Scrub-Jay (Aphelocoma coerulescens).","authors":"Faye G Romero, Felix E G Beaudry, Eyvind Hovmand Warner, Tram N Nguyen, John W Fitzpatrick, Nancy Chen","doi":"10.1093/g3journal/jkae232","DOIUrl":"https://doi.org/10.1093/g3journal/jkae232","url":null,"abstract":"The Florida Scrub-Jay (Aphelocoma coerulescens), a Federally Threatened, cooperatively-breeding bird, is an emerging model system in evolutionary biology and ecology. Extensive individual-based monitoring and genetic sampling for decades has yielded a wealth of data, allowing for the detailed study of social behavior, demography, and population genetics of this natural population. Here, we report a linkage map and a chromosome-level genome assembly and annotation for a female Florida Scrub-Jay made with long-read sequencing technology, chromatin conformation data, and the linkage map. We constructed a linkage map comprising 4,468 SNPs that had 34 linkage groups and a total sex-averaged autosomal genetic map length of 2446.78 cM. The new genome assembly is 1.33 Gb in length, consisting of 33 complete or near-complete autosomes and the sex chromosomes (ZW). This highly contiguous assembly has an NG50 of 68 Mb and a Benchmarking Universal Single-Copy Orthologs (BUSCO) completeness score of 97.1% with respect to the Aves database. The annotated gene set has a BUSCO transcriptome completeness score of 95.5% and 17,964 identified protein-coding genes, 92.5% of which have associated functional annotations. This new, high-quality genome assembly and linkage map of the Florida Scrub-Jay provides valuable tools for future research into the evolutionary dynamics of small, natural populations of conservation concern.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genome report: Genome sequence of tuliptree scale, Toumeyella liriodendri (Gmelin), an ornamental pest insect. 基因组报告：观赏害虫楸鳞 Toumeyella liriodendri (Gmelin) 的基因组序列。

IF 2.1 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-27 DOI: 10.1093/g3journal/jkae231

Andrew J Mongue, Amanda Markee, Ethan Grebler, Tracy Liesenfelt, Erin C Powell

{"title":"Genome report: Genome sequence of tuliptree scale, Toumeyella liriodendri (Gmelin), an ornamental pest insect.","authors":"Andrew J Mongue, Amanda Markee, Ethan Grebler, Tracy Liesenfelt, Erin C Powell","doi":"10.1093/g3journal/jkae231","DOIUrl":"https://doi.org/10.1093/g3journal/jkae231","url":null,"abstract":"Scale insects are of interest both to basic researchers for their unique reproductive biology and to applied researchers for their pest status. In spite of this interest, there remain few genomic resources for this group of insects. To begin addressing this lack of data, we present the genome sequence of tuliptree scale, Toumeyella liriodendri (Gmelin) (Hemiptera: Coccomorpha: Coccidae). The genome assembly spans 536Mb, with over 96% of sequence assembled into one of 17 chromosomal scaffolds. We characterize roughly 66% of this sequence as repetitive and annotate 16,508 protein coding genes. Then we use the reference genome to explore the phylogeny of soft scales (Coccidae) and evolution of karyotype within the family. We find that T. liriodendri is an early-diverging soft scale, less closely related to most sequenced soft scales than a species of the family Aclerdidae is. This molecular result corroborates a previous, morphology-based phylogenetic placement of Aclerdidae within Coccidae. In terms of genome structure, T. liriodendri has nearly twice as many chromosomes as the only other soft scale assembled to the chromosome level, Ericerus pela (Chavannes). In comparing the two, we find that chromosome number evolution can largely be explained by simple fissions rather than more complex rearrangements. These genomic natural history observations lay a foundation for further exploration of this unique group of insects.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Linkage mapping of root shape traits in two carrot populations. 更正：两个胡萝卜种群根形性状的连锁图谱。

IF 2.1 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-27 DOI: 10.1093/g3journal/jkae227

引用次数: 0

Linear poly-ubiquitin remodels the proteome and influences hundreds of regulators in Drosophila. 线性多泛素重塑了果蝇的蛋白质组，并影响了数百种调节因子。

IF 2.1 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-26 DOI: 10.1093/g3journal/jkae209

Oluwademilade Nuga, Kristin Richardson, Nikhil C Patel, Xusheng Wang, Vishwajeeth Pagala, Anna Stephan, Junmin Peng, Fabio Demontis, Sokol V Todi

{"title":"Linear poly-ubiquitin remodels the proteome and influences hundreds of regulators in Drosophila.","authors":"Oluwademilade Nuga, Kristin Richardson, Nikhil C Patel, Xusheng Wang, Vishwajeeth Pagala, Anna Stephan, Junmin Peng, Fabio Demontis, Sokol V Todi","doi":"10.1093/g3journal/jkae209","DOIUrl":"10.1093/g3journal/jkae209","url":null,"abstract":"Ubiquitin controls many cellular processes via its posttranslational conjugation onto substrates. Its use is highly variable due to its ability to form poly-ubiquitin chains with various topologies. Among them, linear chains have emerged as important regulators of immune responses and protein degradation. Previous studies in Drosophila melanogaster found that expression of linear poly-ubiquitin that cannot be dismantled into single moieties leads to their ubiquitination and degradation or, alternatively, to their conjugation onto proteins. However, it remains largely unknown which proteins are sensitive to linear poly-ubiquitin. To address this question, here we expanded the toolkit to modulate linear chains and conducted ultra-deep coverage proteomics from flies that express noncleavable, linear chains comprising 2, 4, or 6 moieties. We found that these chains regulate shared and distinct cellular processes in Drosophila by impacting hundreds of proteins, such as the circadian factor Cryptochrome. Our results provide key insight into the proteome subsets and cellular pathways that are influenced by linear poly-ubiquitin chains with distinct lengths and suggest that the ubiquitin system is exceedingly pliable.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Agar lot-specific inhibition in the plating efficiency of yeast spores and cells. 琼脂批次对酵母孢子和细胞培养效率的抑制作用。

IF 2.1 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-23 DOI: 10.1093/g3journal/jkae229

Reine U Protacio, Mari K Davidson, Emory G Malone, Dominique Helmlinger, Jeremy R Smith, Patrick A Gibney, Wayne P Wahls

{"title":"Agar lot-specific inhibition in the plating efficiency of yeast spores and cells.","authors":"Reine U Protacio, Mari K Davidson, Emory G Malone, Dominique Helmlinger, Jeremy R Smith, Patrick A Gibney, Wayne P Wahls","doi":"10.1093/g3journal/jkae229","DOIUrl":"https://doi.org/10.1093/g3journal/jkae229","url":null,"abstract":"The fission yeast Schizosaccharomyces pombe and the budding yeast Saccharomyces cerevisiae are highly diverged (530 mya), single-celled, model eukaryotic organisms. Scientists employ mating, meiosis, and the plating of ascospores and cells to generate strains with novel genotypes and to discover biological processes. Our three laboratories encountered independently sudden-onset, major impediments to such research. Spore suspensions and vegetative cells no longer plated effectively on minimal media. By systematically analyzing multiple different media components from multiple different suppliers, we identified the source of the problem. Specific lots of agar were toxic. We report that this sporadic toxicity affects independently the agar stocks of multiple vendors, has occurred repeatedly over at least three decades, and extends to species in highly diverged taxa. Interestingly, the inhibitory effects displayed variable penetrance and were attenuated on rich media. Consequently, quality control checks that use only rich media can provide false assurances on the quality of the agar. Lastly, we describe likely sources of the toxicity and we provide specific guidance for quality control measures that should be applied by all vendors as preconditions for their sale of agar.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross Potential Selection: A Proposal for Optimizing Crossing Combinations in Recurrent Selection Using the Usefulness Criterion of Future Inbred Lines. 杂交潜力选择：利用未来近交系的有用性标准优化循环选择中的杂交组合的建议。

IF 2.1 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-23 DOI: 10.1093/g3journal/jkae224

Kengo Sakurai, Kosuke Hamazaki, Minoru Inamori, Akito Kaga, Hiroyoshi Iwata

{"title":"Cross Potential Selection: A Proposal for Optimizing Crossing Combinations in Recurrent Selection Using the Usefulness Criterion of Future Inbred Lines.","authors":"Kengo Sakurai, Kosuke Hamazaki, Minoru Inamori, Akito Kaga, Hiroyoshi Iwata","doi":"10.1093/g3journal/jkae224","DOIUrl":"https://doi.org/10.1093/g3journal/jkae224","url":null,"abstract":"In plant breeding programs, rapid production of novel varieties is highly desirable. Genomic selection allows the selection of superior individuals based on genomic estimated breeding values. However, it is worth noting that superior individuals may not always be superior parents. The choice of the crossing pair significantly influences the genotypic value of the resulting progeny. This study has introduced a new crossing strategy, termed cross potential selection (CPS), designed to expedite the production of novel varieties of inbred crops. CPS integrates fast recurrent selection and usefulness criterion to generate novel varieties. It considers the segregation of each crossing pair and computes the expected genotypic values of the top-performing individuals, assuming that the progeny distribution of genotypic values follows a normal distribution. It does not consider genetic diversity and focuses only on producing a novel variety as soon as possible. We simulated a 30-year breeding program in two scenarios, low heritability (h2 = 0.3) and high heritability (h2 = 0.6), to compare CPS with two other selection strategies. CPS consistently demonstrated the highest genetic gains among the three strategies in early cycles. In the 3rd year of the breeding program with a high heritability (h2 = 0.6), CPS exhibited the highest genetic gains, 138 times that of 300 independent breeding simulations. Regarding long-term improvement, the other selection strategies outperformed CPS. Nevertheless, compared with the other two strategies, CPS achieved significant short-term genetic improvements. CPS is a suitable breeding strategy for the rapid production of varieties within limited time and cost.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mistranslating tRNA variants have anticodon- and sex-specific impacts on Drosophila melanogaster. 错误翻译的 tRNA 变体对黑腹果蝇具有反密码子和性别特异性影响。

IF 2.1 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-23 DOI: 10.1093/g3journal/jkae230

Joshua R Isaacson, Matthew D Berg, Jessica Jagiello, William Yeung, Brendan Charles, Judit Villén, Christopher J Brandl, Amanda J Moehring

{"title":"Mistranslating tRNA variants have anticodon- and sex-specific impacts on Drosophila melanogaster.","authors":"Joshua R Isaacson, Matthew D Berg, Jessica Jagiello, William Yeung, Brendan Charles, Judit Villén, Christopher J Brandl, Amanda J Moehring","doi":"10.1093/g3journal/jkae230","DOIUrl":"10.1093/g3journal/jkae230","url":null,"abstract":"Transfer RNAs (tRNAs) are vital in determining the specificity of translation. Mutations in tRNA genes can result in the misincorporation of amino acids into nascent polypeptides in a process known as mistranslation. Since mistranslation has different impacts, depending on the type of amino acid substitution, our goal here was to compare the impact of different mistranslating tRNASer variants on fly development, lifespan, and behaviour. We established two mistranslating fly lines, one with a tRNASer variant that misincorporates serine at valine codons (V→S) and the other that misincorporates serine at threonine codons (T→S). While both mistranslating tRNAs increased development time and developmental lethality, the severity of the impacts differed depending on amino acid substitution and sex. The V→S variant extended embryonic, larval, and pupal development whereas the T→S only extended larval and pupal development. Females, but not males, containing either mistranslating tRNA presented with significantly more anatomical deformities than controls. Since mistranslation disrupts cellular translation and proteostasis, we also tested the hypothesis that tRNA variants impact fly lifespan. Interestingly, mistranslating females experienced extended lifespan whereas mistranslating male lifespan was unaffected. Consistent with delayed neurodegeneration and beneficial effects of mistranslation, mistranslating flies from both sexes showed improved locomotion as they aged. The ability of mistranslating tRNA variants to have both positive and negative effects on fly physiology and behaviour has important implications for human health given the prevalence of tRNA variants in humans.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Rhg1 copy number variation on a soybean cyst nematode resistance transcriptional network. Rhg1 拷贝数变异对大豆胞囊线虫抗性转录网络的影响。

IF 2.6 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-19 DOI: 10.1093/g3journal/jkae226

Usawadee Chaiprom,Esmaeil Miraeiz,Tong Geon Lee,Jenny Drnevich,Matthew Hudson

{"title":"Impact of Rhg1 copy number variation on a soybean cyst nematode resistance transcriptional network.","authors":"Usawadee Chaiprom,Esmaeil Miraeiz,Tong Geon Lee,Jenny Drnevich,Matthew Hudson","doi":"10.1093/g3journal/jkae226","DOIUrl":"https://doi.org/10.1093/g3journal/jkae226","url":null,"abstract":"Soybean yield loss due to soybean cyst nematode (SCN) infestation has a negative impact on the U.S. economy. Most SCN-resistant soybeans carry a common resistance locus (Rhg1), conferred by copy number variation of a 31.2-kb segment at the Rhg1 locus. To identify the effects of Rhg1 copy number on the plant prior to SCN infection, we investigated genome-wide expression profiles in isogenic Fayette plants carrying different copy numbers at the Rhg1 locus (9-11 copies), that confer different levels of resistance to SCN. We found that even small differences in copy number lead to large changes in expression of downstream defense genes. The co-expression network constructed from differentially expressed genes (DEGs) outside the Rhg1 locus revealed complex effects of Rhg1 copy number on transcriptional regulation involving signal transduction and ethylene-mediated signaling pathways. Moreover, we report a variation in expression levels of phytoalexin biosynthesis-related genes that is correlated with copy number, and the activation of different NBS-LRR gene sets, indicating a broad effect of copy number on defense responses. Using qRT-PCR time series during SCN infection, we validated the SCN responses of DEGs detected in the copy number comparison and showed a stable upregulation of genes related to phytoalexin biosynthesis in resistant Fayette lines during the early stages of the incompatible interaction between soybeans and SCN, before syncytium formation. These results suggest additional genes that could enhance Rhg1-mediated SCN resistance.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Local adaptation can cause both peaks and troughs in nucleotide diversity within populations 局部适应可导致种群内核苷酸多样性出现高峰和低谷

IF 2.6 3区生物学

G3: Genes|Genomes|Genetics Pub Date : 2024-09-18 DOI: 10.1093/g3journal/jkae225

Russ J Jasper, Sam Yeaman

{"title":"Local adaptation can cause both peaks and troughs in nucleotide diversity within populations","authors":"Russ J Jasper, Sam Yeaman","doi":"10.1093/g3journal/jkae225","DOIUrl":"https://doi.org/10.1093/g3journal/jkae225","url":null,"abstract":"The amount of standing variation present within populations is a fundamental quantity of interest in population genetics, commonly represented by calculating the average number of differences between pairs of nucleotide sequences (nucleotide diversity, π). It is well understood that both background and positive selection can cause reductions in nucleotide diversity, but less clear how local adaptation affects it. Depending on the assumptions and parameters, some theoretical studies have emphasized how local adaptation can reduce nucleotide diversity, while others have shown that it can increase it. Here, we explore how local adaptation shapes genome-wide patterns in within-population nucleotide diversity, extending previous work to study the effects of polygenic adaptation, genotypic redundancy, and population structure. We show that local adaptation produces two very different patterns depending on the relative strengths of migration and selection, either markedly decreasing or increasing within-population diversity at linked sites at equilibrium. At low migration, regions of depleted diversity can extend large distances from the causal locus, with substantially more diversity eroded than expected with background selection. With higher migration, peaks occur over much smaller genomic distances but with much larger magnitude changes in diversity. Across spatially extended environmental gradients, both patterns can be found within a single species, with increases in diversity at the center of the range and decreases towards the periphery. Our results demonstrate that there is no universal diagnostic signature of local adaptation based on within-population nucleotide diversity, so it will not be broadly useful for explaining increased FST. However, given that neither background nor positive selection inflate diversity, when peaks are found they suggest local adaptation may be acting on a causal allele in the region.","PeriodicalId":12468,"journal":{"name":"G3: Genes|Genomes|Genetics","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0