Frontiers in Dentistry最新文献_第2页

Oral Rehabilitation of a 4-Year-Old Child with Metaphyseal Chondrodysplasia: A Case Report. 4岁儿童干骺端软骨发育不良的口腔康复1例。

Frontiers in Dentistry Pub Date : 2025-09-03 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i35.19698

Mansi Gandhy Baviskar, Ajit Baviskar

引用次数: 0

A Comparative Evaluation of Midazolam, Ketamine and Their Combination as Sedative Agents in Pediatric Dentistry: A Systematic Review and Meta-analysis. 咪达唑仑、氯胺酮及其联合应用于儿科牙科镇静的比较评价：系统综述和荟萃分析。

Frontiers in Dentistry Pub Date : 2025-08-23 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i34.19562

Matine Gharavi, Katayoun Salem, Seyyed Amir Yasin Ahmadi, Hamid Reza Baradaran

{"title":"A Comparative Evaluation of Midazolam, Ketamine and Their Combination as Sedative Agents in Pediatric Dentistry: A Systematic Review and Meta-analysis.","authors":"Matine Gharavi, Katayoun Salem, Seyyed Amir Yasin Ahmadi, Hamid Reza Baradaran","doi":"10.18502/fid.v22i34.19562","DOIUrl":"10.18502/fid.v22i34.19562","url":null,"abstract":"Objectives: This study reviewed the efficacy of midazolam, ketamine, and their combination for sedation of uncooperative pediatric dental patients. Materials and Methods: Medline, PubMed, Cochrane Central Register of Controlled Trials, and the World Health Organization International Clinical Trials Registry Platform were searched up to August 31, 2023 for randomized controlled trials (RCTs) comparing midazolam, ketamine, and midazolam-ketamine in pediatric patients. Methodological assessment was conducted using the revised Cochrane ROB-2 tool. A dose-response meta-analysis was performed to analyze the effect of oral midazolam dosage on treatment duration (in minutes). Results: Initially, 2,345 records were identified through database searching. After removing the duplicates, 1,230 records remained. Of which, 941 were excluded after title and abstract screening. Subsequently, 289 full-text articles were reviewed; of which, 269 were excluded for various reasons. The remaining 20 publications underwent detailed screening for qualitative synthesis. Risk of bias assessment categorized eight studies as low risk, six with some concerns, and six as having high risk of bias. The meta-analysis, involving three RCTs with 215 children, indicated an increasing trend in treatment duration up to 0.8 mg/kg dosage of oral midazolam. The combination of midazolam-ketamine was highly successful in providing rapid and effective pain relief and sedation for challenging pediatric patients, outperforming either drug alone, irrespective of the administration method. Conclusion: The findings of this systematic review suggest that when it comes to ease of treatment and clinical efficacy, using a combination of midazolam and ketamine is superior to midazolam or ketamine alone.","PeriodicalId":12445,"journal":{"name":"Frontiers in Dentistry","volume":"22 ","pages":"34"},"PeriodicalIF":0.0,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145494079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential Implications of Organoids in Dental Research. 类器官在牙科研究中的潜在意义。

Frontiers in Dentistry Pub Date : 2025-08-20 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i33.19561

Deepti Sharma, George Koshy, Merin S George, Vishal Kumar Sharma

引用次数: 0

Effect of Oral Hygiene Instruction by an Educational Film versus Practical Face-to-Face Instruction on Simplified Oral Hygiene Index of Third Graders: A Clinical Trial. 口腔卫生教育片教学与面对面教学对三年级小学生口腔卫生指标的影响：临床试验

Frontiers in Dentistry Pub Date : 2025-08-13 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i32.19422

Sara Ghadimi, Bahman Seraj, Mehrdad Mohebi, Marzieh Salehi Shahrabi

{"title":"Effect of Oral Hygiene Instruction by an Educational Film versus Practical Face-to-Face Instruction on Simplified Oral Hygiene Index of Third Graders: A Clinical Trial.","authors":"Sara Ghadimi, Bahman Seraj, Mehrdad Mohebi, Marzieh Salehi Shahrabi","doi":"10.18502/fid.v22i32.19422","DOIUrl":"10.18502/fid.v22i32.19422","url":null,"abstract":"Objectives: Oral hygiene instruction is an important step to promote oral health. Educational health promoting interventions focus on knowledge enhancement and adoption of optimal oral health behaviors. The visual media can greatly help in this respect. This study aimed to compare the effect of an educational film versus practical face-to-face instruction on Oral Hygiene Index-Simplified (OHI-S). Materials and Methods: This parallel-design single-blind clinical trial was conducted on 120 third-graders (9-year-olds) in Hamadan city in 2020 who were selected by convenience sampling from 4 random schools. They were randomly assigned to two groups of educational film and practical face-to-face instruction. An educational film was sent to all students through Shaad mobile application. The second group received practical face-to-face oral hygiene instructions. Next, all students were requested to use their own toothbrush for one month. The OHI-S was calculated for students at the onset of the study and at one month after the intervention. Data were analyzed by ANOVA using SPSS version 24. Results: In the practical instruction group, the OHI-S was 1.55±0.45 at one month after the intervention, showing a reduction by 0.25±0.11 units. In the educational film group, the OHI-S was 1.48±0.39 at one month after the intervention, showing a reduction by 0.29±0.19 units. The two groups had no significant difference regarding the reduction of OHI-S (P=0.10). Conclusion: Both practical instruction and educational film effectively decreased the OHI-S of students. Considering the ongoing COVID-19 pandemic, educational film can serve as a suitable alternative to practical face-to-face oral hygiene instruction.","PeriodicalId":12445,"journal":{"name":"Frontiers in Dentistry","volume":"22 ","pages":"32"},"PeriodicalIF":0.0,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12588256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Assessment of Open Flap Debridement Using Magnifying Loupes and Surgical Operating Microscope: A Split-Mouth Randomized Controlled Clinical Trial. 用放大镜和外科手术显微镜进行开瓣清创的临床评价：一项裂口随机对照临床试验。

Frontiers in Dentistry Pub Date : 2025-08-06 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i31.19399

Jaswitha Vintha, Mohan Kumar Pasupuleti, Gautami Subhadra Penmetsa, Sruthima Naga Venkata Satya Gottumukkala, Ramesh Santosh Venkata Konathala, Santosh Vamsi Eagala

{"title":"Clinical Assessment of Open Flap Debridement Using Magnifying Loupes and Surgical Operating Microscope: A Split-Mouth Randomized Controlled Clinical Trial.","authors":"Jaswitha Vintha, Mohan Kumar Pasupuleti, Gautami Subhadra Penmetsa, Sruthima Naga Venkata Satya Gottumukkala, Ramesh Santosh Venkata Konathala, Santosh Vamsi Eagala","doi":"10.18502/fid.v22i31.19399","DOIUrl":"10.18502/fid.v22i31.19399","url":null,"abstract":"Objectives: To overcome the drawbacks of the conventional flap surgery, newer surgical techniques like minimally invasive surgery were evolved to optimize the primary closure of the flap. Using a surgical operating microscope is one such technique, enhancing precession with clinical benefits. The current study aimed to compare the efficacy of a surgical operating microscope versus surgical loupes regarding periodontal treatment outcomes. Materials and Methods: In this split-mouth randomized controlled clinical trial, flap surgery was planned for sites with a pocket probing depth (PPD)≥5mm under a surgical operating microscope and surgical loupes. All clinical periodontal parameters were recorded at baseline, and 3, and 6 months. The patients' perception of postoperative pain and wound healing were also assessed. Results: The study comprised of 20 participants with mild to severe periodontitis. The reduction in the mean PPD was significantly greater at the test site than the control site at 3 months (P=0.05) and 6 months (P=0.005). At 3 months, there was a statistically significant difference in clinical attachment level (CAL) between the test and control sites (P=0.001). Flap surgery performed under a surgical operating microscope significantly enhanced early wound healing and caused less postoperative pain compared to flap surgery performed under surgical loupes (P<0.05). Conclusion: All parameters improved at the test and control sites after the procedure. Nonetheless, the clinical parameters were noticeably better at the test site. Also, the test site had lower postoperative pain and enhanced wound healing compared with the test site.","PeriodicalId":12445,"journal":{"name":"Frontiers in Dentistry","volume":"22 ","pages":"31"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12588103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Preemptive Amitriptyline on Postoperative Pain after Impacted Mandibular Third Molar Extraction: A Randomized Clinical Trial. 预防性阿米替林对下颌阻生第三磨牙拔牙术后疼痛的影响：一项随机临床试验。

Frontiers in Dentistry Pub Date : 2025-08-02 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i30.19398

Farrokh Farhadi, Mohammadhossein Asadi, Saeed Nezafati, Tannaz Pourlak

{"title":"Effect of Preemptive Amitriptyline on Postoperative Pain after Impacted Mandibular Third Molar Extraction: A Randomized Clinical Trial.","authors":"Farrokh Farhadi, Mohammadhossein Asadi, Saeed Nezafati, Tannaz Pourlak","doi":"10.18502/fid.v22i30.19398","DOIUrl":"10.18502/fid.v22i30.19398","url":null,"abstract":"Objectives: Extraction of impacted mandibular third molars is one of the most common procedures in oral and maxillofacial surgery, which is usually associated with significant postoperative pain. This study aimed to evaluate the effect of preemptive amitriptyline on postoperative pain after impacted mandibular third molar extraction. Materials and Methods: This randomized double-blind placebo-controlled clinical trial included 20 patients (n=40 teeth) who referred to the Department of Oral and Maxillofacial Surgery of Tabriz Dental School for bilateral extraction of impacted third molars. After obtaining ethical approval and informed consent, the participants were randomly assigned to two groups: the intervention group received 25 mg amitriptyline preemptively while the control group received a placebo. The primary outcomes included postoperative pain score measured by a visual analog scale (VAS), and the frequency of analgesics taken during the postoperative period. Data were analyzed by paired samples t-test (alpha=0.05). Results: A total of 20 patients (10 males and 10 females) participated in this study, with a mean age of 22.2 years. The mean duration of surgery was almost similar in the two groups (P=0.847). The intervention group consumed significantly lower number of analgesics during the postoperative period than the control group (P<0.001). The time interval from surgery to the first analgesic intake was significantly longer in the amitriptyline group (P<0.001). Conclusion: Preemptive consumption of amitriptyline can effectively reduce postoperative pain and analgesic consumption following impacted mandibular third molar extraction surgery.","PeriodicalId":12445,"journal":{"name":"Frontiers in Dentistry","volume":"22 ","pages":"30"},"PeriodicalIF":0.0,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12588255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tissue Response and Osteoconductive Properties of Forsterite/Poly Lactic Acid Hybrid Nano-Composite Scaffold in Rat. 福斯特石/聚乳酸复合纳米支架在大鼠体内的组织响应及骨传导性能。

Frontiers in Dentistry Pub Date : 2025-07-24 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i29.19213

Parichehr Behfarnia, Paria Biglary, Mohammad Tavakoli, Seyed Mohammad Razavi, Seyed Amir Mirghaderi, Saman Naghieh, Ehsan Foroozmehr, Mahshid Kharaziha

{"title":"Tissue Response and Osteoconductive Properties of Forsterite/Poly Lactic Acid Hybrid Nano-Composite Scaffold in Rat.","authors":"Parichehr Behfarnia, Paria Biglary, Mohammad Tavakoli, Seyed Mohammad Razavi, Seyed Amir Mirghaderi, Saman Naghieh, Ehsan Foroozmehr, Mahshid Kharaziha","doi":"10.18502/fid.v22i29.19213","DOIUrl":"10.18502/fid.v22i29.19213","url":null,"abstract":"Objectives: Objectives: The present research aimed to evaluate the potential of three-dimensional (3D) poly lactic acid (PLA) microstrut scaffolds, surface-modified with nanocomposite gelatin-forsterite fibrous layers possessing porosities of 40% and 70%, to facilitate bone regeneration and angiogenesis in a rat model. Materials and Methods: Thirty-six rats, each with a surgically created cranial defect measuring 4mm in radius, were randomly assigned in a 1:1:1 ratio to one of three experimental groups: A 40% scaffold group (G1), a 70% scaffold group (G2), and a control group receiving no scaffold (G3). Animals were euthanized at either 4 or 8 weeks post-surgery. Histological analysis using hematoxylin and eosin (H&E) staining was performed to observe the tissue response and bone formation within the surgical defects. Histomorphometric assessment was employed to quantify the percentage of newly formed woven and lamellar bone in each group. Results: The mean percentages of total bone formation at 4 weeks were 33.55±4.32%, 37.76±6.20%, and 33.66±2.30% in groups G1, G2, and G3, respectively. At 8 weeks, the corresponding mean percentages were 34.25±1.94%, 37.33±4.30%, and 35.16±3.68% for the same groups. Statical analysis revealed a significant difference in angiogenesis between G1and G2 at 8 weeks (p≤0.01). Conclusion: Our findings demonstrated that the fabricated scaffold exhibited the capacity to facilitate osseous tissue development and promote osteoblast adhesion and infiltration. The scaffolds with 70% porosity showed superior performance in total bone formation compared to those with 40% porosity. This novel scaffold design holds promise for enhancing both angiogenesis and osteogenesis processes.","PeriodicalId":12445,"journal":{"name":"Frontiers in Dentistry","volume":"22 ","pages":"29"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12588107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive Evaluation of Six Flowable Composite Resins in the Market: A Comparative Study. 市场上六种可流动复合树脂的综合评价：比较研究。

Frontiers in Dentistry Pub Date : 2025-07-23 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i28.19206

Sara Abtahi, Sajjad Omidian, Yasaman Sherafatmand, Golnaz Tayebi, Alireza Ranjbar Hassani

{"title":"Comprehensive Evaluation of Six Flowable Composite Resins in the Market: A Comparative Study.","authors":"Sara Abtahi, Sajjad Omidian, Yasaman Sherafatmand, Golnaz Tayebi, Alireza Ranjbar Hassani","doi":"10.18502/fid.v22i28.19206","DOIUrl":"10.18502/fid.v22i28.19206","url":null,"abstract":"Objectives: This study aimed to comprehensively evaluate the mechanical and physical properties of six commercially available flowable dental composite resins, providing critical insights for informed material selection. Materials and Methods: Six flowable composite resin materials namely Edge Flow (EDF), Opallis Flow (OPF), Els Flow (ELF), Denfil Flow (DFF), DX Flow (DXF), and Charisma Flow (CHF) were tested according to ISO 4049 standards. Each material underwent evaluation of depth of cure, flexural strength, solubility, water sorption, and radiopacity. Statistical analyses with ANOVA and post-hoc Tukey test were conducted to identify significant differences among the six study groups (alpha=0.05). Results: Significant material-specific differences were noted in depth of cure and flexural strength among the six study groups (P<0.05). Solubility and water sorption profiles were also significantly different among the study groups (P<0.05). All tested composite resins met the required radiopacity standards, ensuring accurate radiographic diagnosis and monitoring. However, none of the composite groups achieved an exact color match with the A2 reference shade. Conclusion: This study revealed significant differences in mechanical properties of flowable composites, particularly in depth of cure and flexural strength, underscoring the importance of selecting the appropriate material. Shade matching presented ongoing challenges, emphasizing the need for careful material selection. Future research should explore long-term clinical performance and standardized methods for handling of pre-test failures.","PeriodicalId":12445,"journal":{"name":"Frontiers in Dentistry","volume":"22 ","pages":"28"},"PeriodicalIF":0.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145494356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single Injection of Twin Nerve Block in Longstanding Unilateral Temporomandibular Joint Dislocation: A Novel Technique. 单次注射双神经阻滞治疗长期单侧颞下颌关节脱位的新技术。

Frontiers in Dentistry Pub Date : 2025-07-22 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i27.19204

Neeraj Kumar, Richa Kumari

引用次数: 0

Corrosion Resistance and Cytotoxicity of Copper-Based and Nickel-Chromium Alloys for Cast Post and Core Fabrication. 铸造桩芯用铜基和镍铬合金的耐蚀性和细胞毒性。

Frontiers in Dentistry Pub Date : 2025-07-19 eCollection Date: 2025-01-01 DOI: 10.18502/fid.v22i26.19203

Mina Mohaghegh, Mohammad Kazemi, Mehdi Bidaki, Mitra Farzin

{"title":"Corrosion Resistance and Cytotoxicity of Copper-Based and Nickel-Chromium Alloys for Cast Post and Core Fabrication.","authors":"Mina Mohaghegh, Mohammad Kazemi, Mehdi Bidaki, Mitra Farzin","doi":"10.18502/fid.v22i26.19203","DOIUrl":"10.18502/fid.v22i26.19203","url":null,"abstract":"Objectives: This study assessed the corrosion resistance and cytotoxicity of two copper-based alloys and one nickel-chromium (Ni-Cr) alloy used for post and core fabrication. Materials and Methods: In this in vitro study, the corrosion resistance of 9 specimens of dental casting alloys including one Ni-Cr-based (VeraBond) and two copper-based (American Dent-All and Aalbadent NPG) alloys (n=3) was assessed by electrochemical impedance spectroscopy (EIS) in artificial saliva in two different pH levels of 2.5 and 7.1. Their cytotoxicity was evaluated by the methyl thiazolyl tetrazolium (MTT) assay using 15 specimens (n=5). Statistical analysis was performed by one-way ANOVA (alpha=0.05). Results: EIS showed that the Ni-Cr alloy had the highest corrosion resistance. Aalbadent NPG and American Dent-All alloys showed significantly lower corrosion resistance than the Ni-Cr alloy (P<0.05). Aalbadent NPG showed higher corrosion resistance than American Dent-All in early hours, but its corrosion resistance decreased over time and became similar to that of American Dent-All at later time points. Although all groups showed higher corrosion in acidic environment, Ni-Cr showed good corrosion resistance in acidic pH. The cytotoxicity test revealed a significant difference between the copper-based groups (P<0.05). Ni-Cr was the most biocompatible alloy amongst all, followed by Aalbadent NPG. American Dent-All showed a high degree of cytotoxicity. Conclusion: The findings of this study raised some concerns regarding the clinical suitability of copper-based alloys for dental treatments, and the first choice for cast post and core restorations should be Ni-Cr alloys because they are more resistant to corrosion, and are less cytotoxic.","PeriodicalId":12445,"journal":{"name":"Frontiers in Dentistry","volume":"22 ","pages":"26"},"PeriodicalIF":0.0,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12595524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145481126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0