Experimental and Сlinical Urology最新文献

{"title":"Robot-assisted partial nephrectomy with zero ischemia in comorbid patients.","authors":"M. S. Mosoyan, G. Shanava, A. Simonyan, E.S. Gilev, N. A. Aysina","doi":"10.29188/2222-8543-2023-16-2-52-57","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-2-52-57","url":null,"abstract":"Introduction. Nephron-sparing surgery is the current gold standard for the surgical treatment of localized renal cell carcinoma (RCC). Partial nephrectomy can be performed by off-clamp or on clamp techniques. It is especially important to preserve renal function during partial nephrectomy in comorbid patients. Objective. To evaluate the perioperative results of robot-assisted partial nephrectomy with zero ischemia in comorbid patients with RCC. Materials and Methods. At the Almazov Center we retrospectively studied the results of 11 comorbid patients who underwent robot-assisted partial nephrectomy with zero ischemia from 2019 to 2022. In 3 (27.3%) of them, renal mass was detected in a solitary kidney. In preoperative period 3D reconstruction was performed using the 3D Slicer modeling program. For rapid mobilization of the renal vessels we used «method of safe exposure of renal pedicle vessels during endovideosurgical resection of the kidney and radical nephrectomy during laparoscopic and robot-assisted operations» (patent RU 2742367). The boundaries of resection were determined with an intracavitary ultrasound probe BK Flex Focus 800. Renal function was assessed by glomerular filtration rate (GFR) using the Chronic Kidney Desease Epidemiology Collaboration (CKD-EPI) formula. Results. There were no intraoperative and postoperative complications. The median console operation time was 110 min [58–130]. Median estimate blood loss was 100 ml [50-280]. No cases had a positive surgical margin. In the postoperative period, GFR was comparable to preoperative values. Conclusion. Robot-assisted partial nephrectomy with zero ischemia for comorbid patients is more expedient to be performed in a multidisciplinary center of competence. The effectiveness of perioperative results of robot-assisted partial nephrectomy with zero ischemia is achieved by using highly informative diagnostic imaging methods and performing a safe method of isolating renal vessels during the operation with rapid renorrhaphy performed by an experienced surgeon.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124477514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency and nature of symptoms of dysfunction of the lower urinary tract in persons over 40 years old.","authors":"I. Shormanov, A. Soloviev, S. A. Zhigalov, M.I. Azizov","doi":"10.29188/2222-8543-2023-16-12-10-15","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-12-10-15","url":null,"abstract":"Introduction. Symptoms of the lower urinary tract (LUTS) are an underestimated, socially significant problem, especially in the age cohort of patients. LUTS are usually not life-threatening, but the degree of their negative impact on the quality of life is often underestimated and not considered in clinical practice. International epidemiological studies have shown that LUTS affects more than half of the entire adult population with an exponential increase in older age groups. Currently, in the Russian segment of epidemiological studies, there is an obvious shortage of data on the prevalence of LUTS and the structure in adult patients. Aim. To determine the prevalence and structure of symptoms of the lower urinary tract in non-urological patients in the age cohort over 40 years old. Patients and methods. A prospective multicenter epidemiological study was conducted on the basis of data obtained during an anonymous survey of 597 patients who complained to outpatient doctors of a neurological profile: in the period from 2020 to 2022. Inclusion criteria: signing of informed consent to the questionnaire and age over 40 years old. Exclusion criteria: pregnancy and verified urinary tract infection during the month preceding the questionnaire. The questionnaire took into account medical and demographic information, including data on concomitant diseases and ongoing therapy. The classification of the LUTS was carried out according to ICS. Results and discussion. The prevalence of LUTS in the general sample was 58.5; in men – 60,1%, in women – 56,9%. 3 ICS symptom groups (voiding, storage, and postmicturition) were present in 23,6% (women: 23,1%, men: 24,2%), which makes them the most common symptoms according to the ICS classification. In men, the most common symptoms were nocturia and terminal dribbling (34,9% and 25,2%, respectively). Women have nocturia (40,8%) and frequent urination (31,1%). The prevalence of LUTS had a distinct tendency to increase with age (groups: 40-50 years – 45,8%, 50-60 years – 61,4%, ≥60 years – 70,4%. The total percentage of participants with any LUTS who sought healthcare professionals (consultation of a urologist 1 or more times) regarding the LUTS, it was only 27,8%. Conclusion. LUTS is an epidemiologically significant symptom complex that is detected in more than half of adult patients older 40 years old and is constantly increasing with age. At the same time, despite the high incidence, there is a paradoxically low appeal of patients to a specialized specialist.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123034228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of tubeless percutaneous nephrolithotripsy in children.","authors":"A. Vardak, L. D. Arustamov, Y. Rudin, D. Merinov, D. A. Galitskaya, O. Apolikhin, A. Kaprin","doi":"10.29188/2222-8543-2023-16-2-165-172","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-2-165-172","url":null,"abstract":"Introduction. Currently, percutaneous renal surgery is a common surgical procedure in urologic practice for the treatment of large and staghorn renal stones. Placement of a nephrostomy tube has been well recognized as a standard procedure to provide hemostasis, adequate drainage, and access for additional endoscopic procedures. At the same time, the use of a nephrostomy tube has negative consequences such as discomfort/pain symptom, longer hospital stay and possible urine extravasation. In view of the above, draining of the access tract raises questions in some cases. The aim of the study was effectiveness of tubeless percutaneous nephrolithotripsy in the treatment of urolithiasis in children. Materials and methods. Between 2013 and 2019, 66 patients (aged 1-17 y/o) underwent tubeless percutaneous nephrolithotomy (PNL) at the Department of Pediatric Urology of N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology. Patients were divided into three groups depending on the size of the instruments and the way the operation was completed. The first group (n=28) underwent surgery using the mini-PNL technique with the closure of the access tract. The second group (n=21) underwent surgery using the mini-PNL technique in the end of the surgery, moderate bleeding along the tract was detected in order to stop bleeding, a hemostatic matrix with thrombin was introduced. The third group (n=17) underwent surgery using the standard PNL technique and moderate bleeding was also determined in this group with the aim of tubeless completion, a hemostatic matrix with thrombin was introduced. Drainage of the upper urinary tract in the postoperative period was carried out by \"JJ\"-internal and \"J\"-external ureteral stents, which were held for up to 14 days. Results. The complete removal of the calculus in one surgical session was similar in all three groups. In the first group there were 26 (92.8%) children, in the second group 19 (90.4%) and in the third group 16 patients (94.1%). In the first group it was 26 (92.8%) children, in the second group 19 (90.4%) and in the third group 16 patients (94.1%). The need for additional interventions after surgical treatment was 21.4% in the first group, 23.7% in the second and 17.5% in the third group. Febrile fever (persistent temperature 380 C) most often occurred in the first group – in 10.7% of cases, while in the second and third groups this complication was detected in 4.7% and 5.8% of cases, respectively. Gross hematuria in the postoperative period was noted in the group without the use of a hemostatic matrix, averaging 35 (2-115) hours. Conclusion. The proposed tubeless PNL with the use of a hemostatic matrix is indicated for children without bacteriuria, with complete removal of the calculus, in the absence of trauma of the pelvicalyceal system and intensive bleeding. The duration of gross hematuria decreased with the introduction of the matrix in standard tubeless PNL by 51.4% and in mini-PNL b","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124563739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large cist of the tunica albuginea.","authors":"A. Ryzhkov, S. Sokolova, S. A. Zhigalov, I. Shormanov","doi":"10.29188/2222-8543-2023-16-2-86-90","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-2-86-90","url":null,"abstract":"Introduction. A cyst of the tunica albuginea of the testis is a rare benign formation, the prevalence in the male population varies from 0.3 to 0.76%. Cysts of the tunica albuginea are usually small in size from 2 to 5 mm. Clinical case. A case of a large cyst of the tunica albuginea (3.5×2.5×2.9 cm) of the left testicle in a 44-year-old man is presented. In the case presented, the cyst was probably of post-traumatic origin, since the patient had suffered a blunt trauma to the scrotum about 10 years ago. The patient complained of pain in the left half of the scrotum. An operation was performed – microsurgical excision of the cyst of the albuginea of the left testicle. Postoperative period without complications. The pain syndrome was relieved 14 days after the operation. Histological examination – a cystic formation with a connective tissue wall lined with cubic, in places ciliated epithelium. Ultrasound control after 3 months – the size of the left testicle is 4.2 * 2.7 * 1.9 (volume 11.2 cm3), the parenchyma is homogeneous. Conclusion. The presented observation demonstrates that cysts of the albuginea of the testis can reach a significant size, spreading into the testicular parenchyma. Organ-sparing treatment in symptomatic patients with large cysts of the albuginea with intraparenchymal growth allows to eliminate pain symptoms and preserve the residual testicular parenchyma. The use of microsurgical techniques may be useful in minimizing circulatory disturbance and reducing the risk of atrophic changes in the testicular parenchyma.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125179196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New biomarkers of kidney damage and their use in minimally invasive treatment of urolithiasis.","authors":"L. E. Belyi, V. Klochkov, A. Klochkov","doi":"10.29188/2222-8543-2023-16-2-67-75","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-2-67-75","url":null,"abstract":"Introduction. The effect of various minimally invasive treatment for kidney stones on renal function has not been sufficiently studied. To assess the specificity, severity, and prognostic significance of renal injury of urolithiasis and its minimally invasive treatment, it is necessary to search for «biomarkers of injury». The concentration of serum urea and creatinine used in routine clinical practice, the glomerular filtration rate change in the later stages of the disease and are functional parameters. Materials and methods. The data were searched in the PubMed, Web of Science, Google Scholar, еLibrary.ru using the following keywords: «acute kidney injury», «KIM-1», «kidney injury molecule 1», «NGAL», «neutrophil gelatinase- associated lipocalin», «L-FABP», «liver-type fatty acid binding protein», «cystatin C», «retrograde intrarenal surgery», «percutaneous nephrolithotomy», «kidney injury urolithiasis», «kidney injury nephrolithiasis». Results. Today new biomarkers have been proposed to detect renal injury at the initial stages. These are neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, kidney injury molecule-1 (KIM-1) and liver-type fatty acid binding protein (L-FABP). The level of NGAL and KIM-1 increases until the serum creatinine level increases and the corresponding histological changes in the renal parenchyma develop. In percutaneous nephrolithotomy, multiple punctures and postoperative bleeding are independent risk factors for deterioration of renal function in the long term, and the large size and high density of stones, staghorn stones, and long duration of intervention are largely associated with the development of acute renal injury in the early postoperative period. Obstructive uropathy affects kidney damage in the postoperative period. The elimination of obstruction leads to a decrease in KIM-1 in urine already in the early postoperative period. The dynamics of biomarker levels suggests that percutaneous nephrolithotomy causes more renal injury than retrograde intrarenal surgery (RIRS). Conclusion. Аny minimally invasive treatment for kidney stones may lead to renal injury, which is not always accompanied by impaired function. The mechanisms of renal injury in various variants of minimally invasive treatment for kidney stones have specific features, and the short-term and long-term consequences are currently not fully determined. Further research evaluating the effect of various minimally invasive methods of urolithiasis treatment on the condition of the renal tubules using modern biomarkers is needed.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116934723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Instrumental methods for assessing the functional ability of the kidneys.","authors":"M. Prosyannikov, A. Kazachenko, D. Voytko, O. Konstantinova, N. V. Anokhin, A. Gromov, A. Sivkov, O. Apolikhin, A. Kaprin","doi":"10.29188/2222-8543-2023-16-2-76-85","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-2-76-85","url":null,"abstract":"Introduction. Chronic kidney disease (CKD) is a global medical problem. The long-term latent course of the disease leads to a progressive increase in its incidence. Along with laboratory methods of research in the arsenal of the diagnostic service, there are tools that allow you to detect a violation of the kidneys functional ability. Purpose. To analyze modern instrumental methods for diagnosing the functional ability of the kidneys. Materials and methods. The review was conducted based on data published in PubMed databases (https://www.ncbi.nlm.nih.gov/pubmed /) and еLibrary.ru (https://elibrary.ru) and was limited only to articles in scientific peer-reviewed journals. It was carried out until January 2023, by keywords: kidney ultrasound, computed tomography, positron emission tomography, magnetic resonance imaging, kidney function. Results. We found 189 sources not older than 10 years (published after 2012) that were relevant to the topic of the review. Conference abstracts, short messages, duplicate publications were excluded from them. After that, based on the relevance of the data, reliability of sources, impact factors of journals and the sequence of presentation of the material in the manuscript, 46 articles were selected directly for citation in the review. Also, when writing the review, original articles published before 2012 were used. Conclusion. The available modern instrumental methods for assessing renal function open up broad prospects for their clinical application and require further research.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127333086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midurethral synthetic tuneable tension tape in treatment of stress urinary incontinence in women.","authors":"N. Kubin, I. A. Labetov, G. Kovalev, A. S. Shulgin, A. Nuriev, D. Shkarupa","doi":"10.29188/2222-8543-2023-16-2-152-159","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-2-152-159","url":null,"abstract":"Introduction. The use of midurethral synthetic slings is currently considered to be the most widespread treatment option for stress urinary incontinence (SUI). The most difficult in the existing approaches is to achieve the optimal tension of the sling, on which the result of treatment directly depends. To solve this problem, sling systems with the possibility of tension adjustment in the early postoperative period were created. A comparative study of the effectiveness and safety of such a system and a sling without the possibility of adjustment seems to be a relevant task. Materials and Methods. The study involved 320 female patients with a mean age of 55.2±11.2 years and a confirmed diagnosis of SUI. The patients were allocated into two groups: the first group underwent a synthetic suburethral sling by the standard technique (TOT); the second group received a suburethral sling with early mobilization (TTT). All patients underwent stress test, uroflowmetry and ultrasound investigation to determine the volume of residual urine. UDI-6, ICIQ-SF, PISQ-12 questionnaires were filled out to assess subjective efficiency. Results. In the second group, 28% of the patients needed to increase the tension of the prosthesis. Due to the possibility of tightening the sling in the early postoperative period, the operation was ineffective at the delayed follow-up stage at 36 months only in 11% of the women in the TTT group and in 32% of the patients in the LTT group, p<0.001. Loosening the sling tension was required in every fourth patient in the TTT group. Signs of obstructive urination at the stage of 36 months persisted in 13 patients in the TOT group and were completely absent in the TTT group. Subjective satisfaction with treatment was higher in the TTT group and amounted to 82%. Conclusion. A synthetic mid-urethral tuneable tension tape is superior to a classic sling without adjustment capability in long-term efficacy and safety.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130009377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence and neural networks in urology.","authors":"K.K. Shchamkhalova, D. Merinov, A. Artemov, S. Gurbanov","doi":"10.29188/2222-8543-2023-16-2-32-37","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-2-32-37","url":null,"abstract":"Introduction. The review is devoted to the analysis of the world experience in the use of artificial intelligence in medicine and urology. Materials and methods. The review was conducted on the basis of data published in the PubMed, Scientific Electronic Library eLibrary.ru databases and on the professional medical associations websites. The article contains 43 scientific publications. Results. In this literature review, the types of neural networks and the features of their application are considered in detail. Special attention is paid to the use of artificial intelligence in medical imaging, particularly in urology. Effectiveness and accuracy of developing the connectionism method application in artificial neural network (ANN) in recent publications are presented. Advantages and disadvantages of artificial intelligence for a predictive model are outlined. We also considered the main mistakes displayed in publications regarding unreliable or poorly created neural networks and studies in the use of ANNs for clinical practice. Conclusion. The use of neural networks as a tool in the daily clinical practice of a specialist is still limited. The main problems are still the unreliability of the created models and lack of easy-to-use algorithms.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134518562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postcoital cystitis as a cause of sexual dysfunction in women.","authors":"B. Komyakov, V. Ochelenko, M. Shevnin, V. Tarasov, R. Melikov","doi":"10.29188/2222-8543-2023-16-2-134-139","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-2-134-139","url":null,"abstract":"Introduction. Postcoital cystitis is a special form of recurrent cystitis. Against the background of this disease, especially with an aggressive course, the daily activity of patients may change, the quality of life may deteriorate, and sexual dysfunction may develop. Aim. Study the prevalence of sexual dysfunction in patients with recurrent postcoital cystitis, as well as to assess their quality of life. Material and methods. The study compared two groups of patients: the main (first group) and control (second group). The first group included 70 women with recurrent postcoital cystitis. The control group included 70 women without recurrent postcoital cystitis. To assess the prevalence of sexual dysfunction was used: Female Sexual Function Index (FSFI). Patients' quality of life indicators were determined using the SF12v2 questionnaire. Results. The total FSFI score between the groups was statistically significantly different. Sexual dysfunction was detected in patients with recurrent postcoital cystitis in 88.6% of cases, and in 15.7% among women in the control group. Quality of life indicators significantly differed between the groups. More pronounced changes were observed in the mental component of the quality of life. Conclusion. Our data indicate a high incidence of sexual dysfunction in patients with recurrent postcoital cystitis, as well as the impact of postcoital cystitis on the quality of life.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124924219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corporoplasty with synthetic graft in fibroplastic penile induration.","authors":"A. Panferov, E. Bekreev, V. Elagin, S. Kotov","doi":"10.29188/2222-8543-2023-16-1-122-127","DOIUrl":"https://doi.org/10.29188/2222-8543-2023-16-1-122-127","url":null,"abstract":"Introduction. Peyronie's disease is a multifactorial disease leading to various types of penile deformities. Surgical treatment is the most effective method of correcting erectile deviation. In patients with preserved erectile function the technique of plaque incident with grafting is widely used, in the presence of erectile dysfunction phalloprosthesis with plaque incident and grafting should be performed. The question of the choice of material for defect replacement in surgical treatment of Peyronie's disease is relevant, because today none of the used grafts is a reference. Aim of the study. Evaluation of the results of corporoplasty using synthetic grafts in patients with Peyronie's disease. Materials and methods. 11 patients underwent corporoplasty using a synthetic graft made of modified polytetrafluoroethylene (ePTFE), in 4 cases this technique was combined with falloprosthetics. Results. Erectile deviation was eliminated in all patients. At the same time, no early and long-term complications were noted during the follow-up. All patients were satisfied with the outcome of the surgical intervention. Conclusion. Synthetic grafts can be used for surgical treatment of Peyronie's disease with the achievement of a positive effect. The use of this material in the treatment of Peyronie's disease requires further study.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123589372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}