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Know your molecule: pharmacological characterization of drug candidates to enhance efficacy and reduce late-stage attrition 了解你的分子:候选药物的药理学特征,以提高疗效并减少后期损耗。
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-18 DOI: 10.1038/s41573-024-00958-9
Terry Kenakin
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引用次数: 0
Author Correction: The state of the art in secondary pharmacology and its impact on the safety of new medicines 作者更正:二级药理学的最新进展及其对新药安全性的影响。
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-17 DOI: 10.1038/s41573-024-00993-6
Richard J. Brennan, Stephen Jenkinson, Andrew Brown, Annie Delaunois, Bérengère Dumotier, Malar Pannirselvam, Mohan Rao, Lyn Rosenbrier Ribeiro, Friedemann Schmidt, Alicia Sibony, Yoav Timsit, Vicencia Toledo Sales, Duncan Armstrong, Armando Lagrutta, Scott W. Mittlestadt, Russell Naven, Ravikumar Peri, Sonia Roberts, James M. Vergis, Jean-Pierre Valentin
{"title":"Author Correction: The state of the art in secondary pharmacology and its impact on the safety of new medicines","authors":"Richard J. Brennan, Stephen Jenkinson, Andrew Brown, Annie Delaunois, Bérengère Dumotier, Malar Pannirselvam, Mohan Rao, Lyn Rosenbrier Ribeiro, Friedemann Schmidt, Alicia Sibony, Yoav Timsit, Vicencia Toledo Sales, Duncan Armstrong, Armando Lagrutta, Scott W. Mittlestadt, Russell Naven, Ravikumar Peri, Sonia Roberts, James M. Vergis, Jean-Pierre Valentin","doi":"10.1038/s41573-024-00993-6","DOIUrl":"10.1038/s41573-024-00993-6","url":null,"abstract":"","PeriodicalId":122,"journal":{"name":"Allergy","volume":"23 7","pages":"563-563"},"PeriodicalIF":122.7,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41573-024-00993-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141420006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDA approves first telomerase inhibitor FDA 批准首个端粒酶抑制剂
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-14 DOI: 10.1038/d41573-024-00102-7
Asher Mullard
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引用次数: 0
Upcoming market catalysts in Q3 2024 2024 年第三季度即将出现的市场催化剂
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-12 DOI: 10.1038/d41573-024-00099-z
Kaniaw Dilzer
{"title":"Upcoming market catalysts in Q3 2024","authors":"Kaniaw Dilzer","doi":"10.1038/d41573-024-00099-z","DOIUrl":"10.1038/d41573-024-00099-z","url":null,"abstract":"","PeriodicalId":122,"journal":{"name":"Allergy","volume":"23 7","pages":"489-489"},"PeriodicalIF":122.7,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141309001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antisense and CRISPR-based drugs build cases for better hereditary angioedema treatments 基于反义和CRISPR的药物为更好地治疗遗传性血管性水肿提供了案例
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-11 DOI: 10.1038/d41573-024-00101-8
Asher Mullard
{"title":"Antisense and CRISPR-based drugs build cases for better hereditary angioedema treatments","authors":"Asher Mullard","doi":"10.1038/d41573-024-00101-8","DOIUrl":"10.1038/d41573-024-00101-8","url":null,"abstract":"","PeriodicalId":122,"journal":{"name":"Allergy","volume":"23 7","pages":"488-488"},"PeriodicalIF":122.7,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141304517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chromatin-targeted drug discovery at “a very special moment” 处于 "非常特殊时刻 "的染色质靶向药物发现
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-11 DOI: 10.1038/d41573-024-00096-2
Asher Mullard
{"title":"Chromatin-targeted drug discovery at “a very special moment”","authors":"Asher Mullard","doi":"10.1038/d41573-024-00096-2","DOIUrl":"10.1038/d41573-024-00096-2","url":null,"abstract":"Cigall Kadoch, a cancer researcher at Dana-Farber Cancer Institute and co-founder of Foghorn Therapeutics, discusses the case for a new wave of epigenetic drugs, targeting chromatin remodelling complexes. Cigall Kadoch, a cancer researcher at Dana-Farber Cancer Institute and co-founder of Foghorn Therapeutics, discusses the case for a new wave of epigenetic drugs, targeting chromatin remodelling complexes.","PeriodicalId":122,"journal":{"name":"Allergy","volume":"23 7","pages":"490-491"},"PeriodicalIF":122.7,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141304382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RNA delivery heats up cold tumours RNA 输送为寒冷的肿瘤升温
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-10 DOI: 10.1038/d41573-024-00098-0
M. Teresa Villanueva
{"title":"RNA delivery heats up cold tumours","authors":"M. Teresa Villanueva","doi":"10.1038/d41573-024-00098-0","DOIUrl":"10.1038/d41573-024-00098-0","url":null,"abstract":"","PeriodicalId":122,"journal":{"name":"Allergy","volume":"23 7","pages":"497-497"},"PeriodicalIF":122.7,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141299009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expanding the psychedelic toolkit 扩展迷幻药工具包。
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-10 DOI: 10.1038/d41573-024-00100-9
Katie Kingwell
{"title":"Expanding the psychedelic toolkit","authors":"Katie Kingwell","doi":"10.1038/d41573-024-00100-9","DOIUrl":"10.1038/d41573-024-00100-9","url":null,"abstract":"","PeriodicalId":122,"journal":{"name":"Allergy","volume":"23 7","pages":"496-496"},"PeriodicalIF":122.7,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A route to small-molecule Lp(a) inhibitors for heart disease 治疗心脏病的小分子脂蛋白(a)抑制剂之路
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-10 DOI: 10.1038/d41573-024-00097-1
Isobel Leake
{"title":"A route to small-molecule Lp(a) inhibitors for heart disease","authors":"Isobel Leake","doi":"10.1038/d41573-024-00097-1","DOIUrl":"10.1038/d41573-024-00097-1","url":null,"abstract":"","PeriodicalId":122,"journal":{"name":"Allergy","volume":"23 7","pages":"498-498"},"PeriodicalIF":122.7,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141298927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDA approves mRNA-based RSV vaccine FDA 批准基于 mRNA 的 RSV 疫苗
IF 122.7 1区 医学
Allergy Pub Date : 2024-06-07 DOI: 10.1038/d41573-024-00095-3
Asher Mullard
{"title":"FDA approves mRNA-based RSV vaccine","authors":"Asher Mullard","doi":"10.1038/d41573-024-00095-3","DOIUrl":"10.1038/d41573-024-00095-3","url":null,"abstract":"","PeriodicalId":122,"journal":{"name":"Allergy","volume":"23 7","pages":"487-487"},"PeriodicalIF":122.7,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141287146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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