Expert Review of Gastroenterology & Hepatology最新文献_第9页

Development and validation of a risk model to predict the progression of ulcerative colitis patients to acute severe disease within one year. 预测溃疡性结肠炎患者在一年内发展为急性重症的风险模型的开发和验证。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2279737

Jie Chen, Yue Zhang, Qiong Guo, Tianqi Ren, Nana Tang, Han Chen, Hongjie Zhang

{"title":"Development and validation of a risk model to predict the progression of ulcerative colitis patients to acute severe disease within one year.","authors":"Jie Chen, Yue Zhang, Qiong Guo, Tianqi Ren, Nana Tang, Han Chen, Hongjie Zhang","doi":"10.1080/17474124.2023.2279737","DOIUrl":"10.1080/17474124.2023.2279737","url":null,"abstract":"Background and aims: Acute severe ulcerative colitis (ASUC) is strongly associated with poor prognosis. We aimed to establish and validate a model predicting ASUC occurrence within 1 year after ulcerative colitis(UC) diagnosis.Methods: A cohort of UC patients diagnosed between 2018 and 2020 at Northern Jiangsu People's Hospital, who were followed up for one year, was used to develop a risk prediction model. An independent cohort from January to December 2021, monitored until December 2022 at the at the First Affiliated Hospital of Nanjing Medical University, was used for external validation. A multivariable logistic regression analysis was conducted to investigate the adjusted association between six risk factors and ASUC. Subsequently, a simplified model was developed by eliminating a relatively insignificant risk factor to create an easy-to-use index.Results: The prediction model incorporates five parameters: disease extent, endoscopic appearance, histopathology, baseline response medication, and relapse frequency. It generates a nomogram in the end. The discriminant ability (c-index) was separately calculated as 0.982 and 0.925 in the development and validation cohorts.Conclusions: The risk prediction model for developing ASUC within one year demonstrated excellent reliability and validity, which could be a straightforward and clinically valuable tool for predicting ASUC occurrence within 1 year.Clinical trial registration: ChiCTR2300071794.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1341-1348"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71479937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An overview of the efficacy, safety, and predictors of achalasia treatments. 贲门失弛缓症治疗的疗效、安全性和预测因素综述。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2286279

Elise M Wessels, Gwen M C Masclee, Albert J Bredenoord

{"title":"An overview of the efficacy, safety, and predictors of achalasia treatments.","authors":"Elise M Wessels, Gwen M C Masclee, Albert J Bredenoord","doi":"10.1080/17474124.2023.2286279","DOIUrl":"10.1080/17474124.2023.2286279","url":null,"abstract":"Introduction: Achalasia is a rare esophageal motility disorder characterized by abnormal esophageal peristalsis and the inability of the lower esophageal sphincter to relax, resulting in poor esophageal emptying. This can be relieved by endoscopic and surgical treatments; each comes with certain advantages and disadvantages.Areas covered: This review aims to guide the clinician in clinical decision making on the different treatment options for achalasia regarding the efficacy, safety, and important predictors.Expert opinion: Botulinum toxin injection is only recommended for a selective group of achalasia patients because of the short term effect. Pneumatic dilation improves achalasia symptoms, but this effect diminishes over time and requiring repeated dilations to maintain clinical effect. Heller myotomy combined with fundoplication and peroral endoscopic myotomy are highly effective on the long term but are more invasive than dilations. Gastro-esophageal reflux complaints are more often encountered after peroral endoscopic myotomy. Patient factors such as age, comorbidities, and type of achalasia must be taken into account when choosing a treatment. The preference of the patient is also of great importance and therefore shared decision making has to play a fundamental role in deciding about treatment.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1241-1254"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136397112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Noninvasive electrical neuromodulation for gastrointestinal motility disorders. 胃肠运动障碍的无创神经电调节。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2288156

Jieyun Yin, Jiande Dz Chen

{"title":"Noninvasive electrical neuromodulation for gastrointestinal motility disorders.","authors":"Jieyun Yin, Jiande Dz Chen","doi":"10.1080/17474124.2023.2288156","DOIUrl":"10.1080/17474124.2023.2288156","url":null,"abstract":"Introduction: Gastrointestinal motility disorders are highly prevalent without satisfactory treatment. noninvasive electrical neuromodulation is an emerging therapy for treating various gastrointestinal motility disorders.Areas covered: In this review, several emerging noninvasive neuromodulation methods are introduced, including transcutaneous auricular vagal nerve stimulation, percutaneous auricular vagal nerve stimulation, transcutaneous cervical vagal nerve stimulation, transcutaneous electrical acustimulation, transabdominal interference stimulation, tibial nerve stimulation, and translumbosacral neuromodulation therapy. Their clinical applications in the most common gastrointestinal motility are discussed, including gastroesophageal reflux disease, functional dyspepsia, gastroparesis, functional constipation, irritable bowel syndrome, and fecal incontinence. PubMed database was searched from 1995 to June 2023 for relevant articles in English.Expert opinion: Noninvasive neuromodulation is effective and safe in improving both gastrointestinal symptoms and dysmotility; it can be used when pharmacotherapy is ineffective. Future directions include refining the methodology, improving device development and understanding mechanisms of action.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1221-1232"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10842705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138451321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

To STRIDE or not to STRIDE: a critique of "treat to target" in Crohn´s disease. STRIDE与否：对克罗恩病 "靶向治疗 "的批判。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2296564

Klaus R Herrlinger, Eduard F Stange

{"title":"To STRIDE or not to STRIDE: a critique of \"treat to target\" in Crohn´s disease.","authors":"Klaus R Herrlinger, Eduard F Stange","doi":"10.1080/17474124.2023.2296564","DOIUrl":"10.1080/17474124.2023.2296564","url":null,"abstract":"Introduction: The STRIDE consensus suggested to focus on mucosal healing, based on biomarkers and endoscopy, in addition to clinical endpoints as treatment target. This narrative review provides a critique of this concept in Crohn´s disease.Areas covered: We analyze and discuss the limitations of endpoints as targets, their currently limited achievability, and the controversial evidence relating to 'treat to target.' The relevant publications in Pubmed were identified in a literature review with the key word 'Crohn´s disease.'Expert opinion: All targets and endpoints have their limitations, and, even if reached, not all have unequivocally been shown to improve prognosis. The major deficiency of STRIDE is not only the lack of validation and agreement upon endpoints but little evidence of their achievability in a sizable proportion of patients by dose or timing adjustments or switching the medication. Above all, the concept should be based on clear evidence that patients indeed benefit from appropriate escalation of treatment and relevant controlled studies in this regard have been controversial. Until the STRIDE approach is proven to be superior to standard treatment focusing on clinical well-being, the field should remain reluctant and expect more convincing evidence before new targets are approved.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1205-1219"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138829123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nosocomial spontaneous bacterial peritonitis is associated with high mortality - a systematic review and meta-analysis. 医院源性自发性细菌性腹膜炎与高死亡率相关——一项系统综述和荟萃分析。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2284825

Mubeen Khan Mohammed Abdul, Karim T Osman, Joseph M Cappuccio, Carol Spencer, Sanjaya K Satapathy

{"title":"Nosocomial spontaneous bacterial peritonitis is associated with high mortality - a systematic review and meta-analysis.","authors":"Mubeen Khan Mohammed Abdul, Karim T Osman, Joseph M Cappuccio, Carol Spencer, Sanjaya K Satapathy","doi":"10.1080/17474124.2023.2284825","DOIUrl":"10.1080/17474124.2023.2284825","url":null,"abstract":"Introduction: It is unclear if Nosocomial Spontaneous Bacteria Peritonitis (NSBP) is associated with higher mortality compared with community acquired spontaneous bacterial peritonitis.Methods: Database search from inception to May 2022 was conducted. The databases included MEDLINE, EMBASE, Cochrane registry of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus. Inclusion criteria were as follows: adult patients, age >18 years, with a diagnosis of NSBP. Pooled estimates of mortality were calculated following the restricted maximum likelihood method. The mortality rate between NSBP and CA-SBP was reported as odds ratio (OR) and 95% confidence interval (CI). Data synthesis was obtained using random effects meta-analysis. Heterogeneity was reported as I2.Results: A total of 482 unique titles were screened. Twenty-two articles were included. A total of 2,145 patients with NSBP were included. Patients were followed for a median of 90 days. The pooled mortality rate of NSBP was 52.51% (95% CI 42.77-62.06%; I2 83.72%). Seven studies compared the mortality outcome of patients with NSBP and CA-SBP. NSBP was significantly associated with a higher rate of mortality (OR 2.78, 95% CI 1.87-4.11; I2 36.00%).Conclusion: NSBP was associated with higher mortality rate compared to CA-SBP, which could be due to a higher rate of resistance organisms.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1333-1339"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138046685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the molecular and genetic mechanisms underlying gut motility disorders. 评估肠道运动紊乱的分子和遗传机制。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2296558

Atchariya Chanpong, Maria M Alves, Elena Bonora, Roberto De Giorgio, Nikhil Thapar

{"title":"Evaluating the molecular and genetic mechanisms underlying gut motility disorders.","authors":"Atchariya Chanpong, Maria M Alves, Elena Bonora, Roberto De Giorgio, Nikhil Thapar","doi":"10.1080/17474124.2023.2296558","DOIUrl":"10.1080/17474124.2023.2296558","url":null,"abstract":"Introduction: Gastrointestinal (GI) motility disorders comprise a wide range of different diseases affecting the structural or functional integrity of the GI neuromusculature. Their clinical presentation and burden of disease depends on the predominant location and extent of gut involvement as well as the component of the gut neuromusculature affected.Areas covered: A comprehensive literature review was conducted using the PubMed and Medline databases to identify articles related to GI motility and functional disorders, published between 2016 and 2023. In this article, we highlight the current knowledge of molecular and genetic mechanisms underlying GI dysmotility, including disorders of gut-brain interaction, which involve both GI motor and sensory disturbance.Expert opinion: Although the pathophysiology and molecular mechanisms underlying many such disorders remain unclear, recent advances in the assessment of intestinal tissue samples, genetic testing with the application of 'omics' technologies and the use of animal models will provide better insights into disease pathogenesis as well as opportunities to improve therapy.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1301-1312"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138829121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative endoscopic ultrasound-guided biliary drainage for primary drainage in obstructive jaundice. 术前内镜超声引导胆道引流术，用于梗阻性黄疸的初次引流。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2293813

Shuntaro Mukai, Takao Itoi

{"title":"Preoperative endoscopic ultrasound-guided biliary drainage for primary drainage in obstructive jaundice.","authors":"Shuntaro Mukai, Takao Itoi","doi":"10.1080/17474124.2023.2293813","DOIUrl":"10.1080/17474124.2023.2293813","url":null,"abstract":"Introduction: Endoscopic transpapillary approach by endoscopic retrograde cholangiopancreatography (ERCP) is the established technique for preoperative biliary drainage (PBD). Recently, endoscopic ultrasound-guided biliary drainage (EUS-BD) has been reported to be a useful alternative technique after ERCP fail. However, the optimal strategy remain controversial.Area covered: This review summarizes the literature on EUS-BD techniques for PBD with a literature search using PubMed, Web of Science, and the Cochrane Central Register of Controlled Trials database between 2000 and 2023 using keywords for 'preoperative biliary drainage' and all types of EUS-BD techniques.Expert opinion: As there is no consensus on the optimal EUS-BD technique for PBD, selection of the EUS-BD approach depends on the patient's condition, the biliary obstruction site, the anastomosis after surgical intervention, and the preference of the endoscopist. However, we consider that EUS-HGS using a dedicated plastic stent may have some advantages in the adverse impact of surgical procedure because the location where the fistula is created by EUS-HGS is away from the site of the surgical procedure. Although there remain many issues that require further investigation, EUS-BD can be a feasible and safe alternative method of PBD for malignant biliary obstruction after ERCP fail.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1197-1204"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138829122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Securing the diagnosis of HRS-AKI: implications for current therapies. 确保rs - aki的诊断:对当前治疗的影响。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2284189

Arpan Mohanty, Andrés Cárdenas

{"title":"Securing the diagnosis of HRS-AKI: implications for current therapies.","authors":"Arpan Mohanty, Andrés Cárdenas","doi":"10.1080/17474124.2023.2284189","DOIUrl":"10.1080/17474124.2023.2284189","url":null,"abstract":"Introduction: Hepatorenal syndrome (HRS)-acute kidney injury (HRS-AKI) is a specific type of kidney injury seen in patients with cirrhosis and ascites and is associated with high mortality and morbidity. It is characterized by rapid deterioration of renal function due to reduced renal blood flow secondary to portal hypertensive splanchnic and systemic vasodilation. Early diagnosis and treatment of HRS-AKI are associated with greater likelihood of improvement in renal function, lower need for dialysis, and better post-transplant outcomes.Areas covered: This review discusses the diagnostic criteria for HRS-AKI, which has undergone several key changes over the last decade, with an aim to secure an early diagnosis and aid swift treatment initiation. Additionally, this review outlines the current treatment paradigms for HRS-AKI.Expert opinion: In the last 20 years, there have been several advances in understanding the pathophysiology and natural course of HRS-AKI. These have led to critical changes in its definition and diagnostic algorithm. However, prognosis of HRS-AKI remains dismal with no significant improvement in HRS-AKI reversal or HRS-related mortality over this time. We discuss several gaps in the current understanding and management of HRS-AKI that will benefit from further research.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1233-1239"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138046686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review and meta-analysis on GERD after OAGB: rate, treatments, and success. 关于 OAGB 术后胃食管反流病的系统回顾和荟萃分析：发病率、治疗方法和成功率。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2296992

Amir Hossein Davarpanah Jazi, Shahab Shahabi, Erfan Sheikhbahaei, Salvatore Tolone, Mehdi El Skalli, Ali Kabir, Rohollah Valizadeh, Mohammad Kermansaravi

{"title":"A systematic review and meta-analysis on GERD after OAGB: rate, treatments, and success.","authors":"Amir Hossein Davarpanah Jazi, Shahab Shahabi, Erfan Sheikhbahaei, Salvatore Tolone, Mehdi El Skalli, Ali Kabir, Rohollah Valizadeh, Mohammad Kermansaravi","doi":"10.1080/17474124.2023.2296992","DOIUrl":"10.1080/17474124.2023.2296992","url":null,"abstract":"Introduction: This review aims to investigate the gastroesophageal reflux disease (GERD) as one of the important concerns for both surgeons and patients after one anastomosis gastric bypass (OAGB).Method: PubMed, Scopus, Embase, Web of Science, and Cochrane were reviewed by the end of the 2021 with keywords relating to GERD, OAGB, and their equivalents. Data regarding OAGB, number of patients with GERD, treatment for GERD, endoscopy findings, the interval between GERD and OAGB were retrieved by two independent investigators. The primary effect/effect size measure was prevalence.Results: 40 studies examining 17,299 patients were included revealing that 2% of patients experience GERD following OAGB. Reflux after revisional OAGB is six times higher than primary OAGB. Despite being unclear, medical and surgical treatments for GERD after OAGB were used in 60% and 41% of patients with estimated success rate of 85% and 100%, respectively.Conclusion: Based on how GERD was identified after OAGB, its rate ranged from 0 to 55%; the pooled rate of 2% is near to Roux-en-Y gastric bypass. GERD symptoms can be mild to be tolerated without medical treatment, moderate that respond to acid-reducing agents, or severe enough that are categorized as interactable and would need a surgical intervention.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1321-1332"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139039714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging in pediatric disorders of the gut-brain interactions: current best practice and future directions. 儿童脑肠相互作用疾病的影像学:当前最佳实践和未来方向。

IF 3.9 3区医学

Expert Review of Gastroenterology & Hepatology Pub Date : 2023-12-01 Epub Date: 2024-01-17 DOI: 10.1080/17474124.2023.2288164

Shaman Rajindrajith, Wathsala Hathagoda, Eranga Ganewatte, Niranga Manjuri Devanarayana, Nikhil Thapar, Marc Benninga

{"title":"Imaging in pediatric disorders of the gut-brain interactions: current best practice and future directions.","authors":"Shaman Rajindrajith, Wathsala Hathagoda, Eranga Ganewatte, Niranga Manjuri Devanarayana, Nikhil Thapar, Marc Benninga","doi":"10.1080/17474124.2023.2288164","DOIUrl":"10.1080/17474124.2023.2288164","url":null,"abstract":"Introduction: Disorders of Gut-Brain Interactions (DGBI) are a common clinical problem in children and pose significant challenges to the attending pediatrician. Radiological investigations are commonly ordered to evaluate these children.Area covered: This review focuses on the current best practice of using radiological investigations in DGBIs and how novel radiological investigations could revolutionize the assessment and therapeutic approach of DGBI in children.Expert opinion: We believe imaging in DGBI is still in its early stages, but it has the potential to revolutionize how we diagnose and treat children with DGBI. As the understanding of the gut-brain axis continues to grow, we can expect to see the disappearance of conventional imaging techniques and the emergence of more sophisticated imaging techniques with less radiation exposure in the future which provide more clinically meaningful information regarding the gut-brain axis and its influence on intestinal function. Some of the novel imaging modalities will be able to broaden our horizon of understanding DGBI in children providing more useful therapeutic options to minimize their suffering.","PeriodicalId":12257,"journal":{"name":"Expert Review of Gastroenterology & Hepatology","volume":" ","pages":"1255-1266"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138298850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0