Colonic diverticular disease revisited.

IF 3.8 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Expert Review of Gastroenterology & Hepatology Pub Date : 2024-12-19 DOI:10.1080/17474124.2024.2438708

Arjuna Priyadarsin de Silva, Nilushi Nuwanshika, Uditha Dassanayake, Madunil Anuk Niriella, Poornima Ranasinghe, H Janaka de Silva

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引用次数: 0

Abstract

Introduction: Diverticular disease, including diverticulosis and diverticulitis, presents a significant health concern globally, with increasing prevalence in Western societies and emerging trends in Asia. The incidence of diverticulitis, is on the rise, leading to significant morbidity and healthcare costs.

Areas covered: A literature search was conducted using the PubMed database, and studies published between 1995 and 2024 were selected based on their relevance to the overall understanding of disease. This review investigates the clinical spectrum, classification, and management strategies of diverticular disease, focusing particularly on evolving trends in diagnosis and treatment. Discussions regarding the prevalence of diverticulosis, the identification of risk factors associated with disease progression, recent advancements in research, and the utilization of biomarkers in disease monitoring and treatment decision-making are considered in detail.

Expert opinion: The discourse on diverticular disease underscores the pressing need for tailored management strategies and innovative treatments. Understanding the intricacies of the disease's pathophysiology is paramount for effective intervention. Recent advances in diagnostic imaging and biomarker identification are promising, yet more research is imperative to further refine patient care. Advances in these areas hold the potential for significantly improving outcomes in disease management.

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导言：憩室疾病，包括憩室病和憩室炎，是全球关注的重大健康问题，在西方社会发病率不断上升，在亚洲也呈现出新的趋势。憩室炎的发病率呈上升趋势，导致严重的发病率和医疗费用：我们使用 PubMed 数据库进行了文献检索，并根据其对疾病总体认识的相关性，选择了 1995 年至 2024 年间发表的研究。这篇综述研究了憩室疾病的临床范围、分类和管理策略，尤其关注诊断和治疗方面不断发展的趋势。文中详细讨论了憩室病的发病率、与疾病进展相关的风险因素的识别、最新研究进展以及生物标记物在疾病监测和治疗决策中的应用：关于憩室疾病的讨论强调了对量身定制的管理策略和创新治疗方法的迫切需要。了解该疾病错综复杂的病理生理学是有效干预的关键。诊断成像和生物标志物鉴定方面的最新进展令人充满希望，但要进一步完善患者护理，还必须开展更多的研究。这些领域的进展有可能显著改善疾病管理的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Gastroenterology & Hepatology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

6.80

自引率

2.60%

发文量

审稿时长

6-12 weeks

期刊介绍： The enormous health and economic burden of gastrointestinal disease worldwide warrants a sharp focus on the etiology, epidemiology, prevention, diagnosis, treatment and development of new therapies. By the end of the last century we had seen enormous advances, both in technologies to visualize disease and in curative therapies in areas such as gastric ulcer, with the advent first of the H2-antagonists and then the proton pump inhibitors - clear examples of how advances in medicine can massively benefit the patient. Nevertheless, specialists face ongoing challenges from a wide array of diseases of diverse etiology.