The Ceylon medical journal最新文献_第8页

Thrombotic microangiopathy in a patient with primary dengue fever. 原发性登革热患者的血栓性微血管病变。

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/cmj.v61i1.8262

N A Bartholameuz, A. Ratnatilaka, B. Jayaratne

引用次数: 1

Risk estimates of cardiovascular diseases in a Sri Lankan community. 斯里兰卡社区心血管疾病的风险估计。

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/cmj.v61i1.8253

U. Ranawaka, C. Wijekoon, A. Pathmeswaran, A. Kasturiratne, Gunasekera Dp, S. Chackrewarthy, N. Kato, A. Wickramasinghe

{"title":"Risk estimates of cardiovascular diseases in a Sri Lankan community.","authors":"U. Ranawaka, C. Wijekoon, A. Pathmeswaran, A. Kasturiratne, Gunasekera Dp, S. Chackrewarthy, N. Kato, A. Wickramasinghe","doi":"10.4038/cmj.v61i1.8253","DOIUrl":"https://doi.org/10.4038/cmj.v61i1.8253","url":null,"abstract":"OBJECTIVES\u0000Quantifying the risk of cardiovascular disease (CVD) in a community is important in planning preventive strategies, but such data are limited from developing countries, especially South Asia. We aimed to estimate the risks of coronary heart disease (CHD), total CVD, and CVD mortality in a Sri Lankan community.\u0000\u0000\u0000METHODS\u0000A community survey was conducted in an urban health administrative area among individuals aged 35-64 years, selected by stratified random sampling. Their 10-year CHD, total CVD, and CVD mortality risks were estimated using three risk prediction tools: National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III), Systematic Coronary Risk Evaluation (SCORE), and World Health Organisation/ International Society of Hypertension (WHO/ISH) charts.\u0000\u0000\u0000RESULTS\u0000Among study participants (n=2985), 54.5% were females, and mean age (SD) was 52.4 (7.8) years. According to NCEP-ATP III ('hard' CHD risk), WHO/ISH (total CVD risk), and SCORE (CVD mortality risk) criteria, 25.4% (95% CI 23.6-27.2), 8.2% (95% CI 7.3-9.2), and 11.8 (95% CI 10.5-13.1) respectively were classified as at 'high risk'. The proportion of high risk participants increased with age. 'High risk' was commoner among males (30.3% vs 20.6%, p<0.001) according to NCEPATP III criteria, but among females (9.7% vs. 6.7%, p<0.001) according to WHO/ISH criteria. No significant gender difference was noted in SCORE risk categories.\u0000\u0000\u0000CONCLUSIONS\u0000A large proportion of individuals in this community are at risk of developing cardiovascular diseases, especially in older age groups. Risk estimates varied with the different prediction tools, and were comparatively higher with NCEP-ATP III charts.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115264049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Validation of the Sinhala version of the Pittsburgh Sleep Quality Index. 僧伽罗语版匹兹堡睡眠质量指数的验证。

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/cmj.v61i1.8255

D. Anandakumar, M. Dayabandara, S. Ratnatunga, R. Hanwella, V. D. de Silva

{"title":"Validation of the Sinhala version of the Pittsburgh Sleep Quality Index.","authors":"D. Anandakumar, M. Dayabandara, S. Ratnatunga, R. Hanwella, V. D. de Silva","doi":"10.4038/cmj.v61i1.8255","DOIUrl":"https://doi.org/10.4038/cmj.v61i1.8255","url":null,"abstract":"INTRODUCTION\u0000Pittsburg Sleep Quality Index (PSQI) is a widely used standardized instrument to assess sleep quality in clinical and research settings. Objective of the study was to translate the PSQI into Sinhala language and validate using a combined qualitative and quantitative approach.\u0000\u0000\u0000METHODS\u0000Every fifth patient aged 18-60 years who attended the out-patients department of a tertiary care hospital was recruited. PSQI was translated into Sinhala using a combined qualitative and quantitative approach. Internal consistency was measured using Cronbach's alpha. Construct validity was assessed by comparing the scores in patients who were identified as having depressive disorder according to the Centre for Epidemiologic Studies Depression Scale (CES-D) and those without depressive disorder.\u0000\u0000\u0000RESULTS\u0000Forty-six participants with depression were compared with 159 non depressed controls. Mean PSQI component scores were significantly higher in depressed patients in 5 components. Factor analysis identified a single component explaining 53.53% of the variance. Cronbach's alpha of 0.85 indicated a high internal consistency.\u0000\u0000\u0000CONCLUSIONS\u0000The Sinhala translation of the PSQI is a valid and reliable tool to assess sleep quality.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128821806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Quadriparesis after a wasp sting. 被黄蜂蜇伤后四肢瘫痪。

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/cmj.v61i1.8265

A. Narayan, R. Mohan, M. Gowda, J. Finsterer, M. Frank

引用次数: 0

A study on silicosis among employees of a silica processing factory in the Central Province of Sri Lanka. 斯里兰卡中部省二氧化硅加工厂员工矽肺病研究。

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/cmj.v61i1.8252

A. Siribaddana, K. Wickramasekera, W. Palipana, M. Peiris, B. A. Upul, K. Senevirathna, D. Dassanayake

{"title":"A study on silicosis among employees of a silica processing factory in the Central Province of Sri Lanka.","authors":"A. Siribaddana, K. Wickramasekera, W. Palipana, M. Peiris, B. A. Upul, K. Senevirathna, D. Dassanayake","doi":"10.4038/cmj.v61i1.8252","DOIUrl":"https://doi.org/10.4038/cmj.v61i1.8252","url":null,"abstract":"OBJECTIVES\u0000The silica industry is rapidly expanding in Sri Lanka. The main objective of this study was to assess the prevalence of silicosis among workers exposed to silica dust, and to describe the disease pattern of the affected. We also screened the affected workers for tuberculosis.\u0000\u0000\u0000METHODS\u0000Employees of a silica factory (n=250) were screened using a questionnaire. Details of duration of silica exposure and work category within the industry were recorded. All symptomatic workers were investigated with chest radiography and screened for tuberculosis. International Labour Organisation criteria for diagnosis of silicosis were used for diagnosis.\u0000\u0000\u0000RESULTS\u0000Of the 250 employees 25 (10%) had respiratory symptoms. Chest radiographs of 14 workers (5.6%) showed abnormalities diagnostic of silicosis. The mean age of the affected workers was 29 years. One worker had radiological changes suggestive of progressive massive fibrosis. Of 14 patients, 13 had duration of exposure less than 10 years suggestive of accelerated silicosis. Among the 14 workers diagnosed with silicosis five (35.7%) had Mantoux induration of more than 10 mm suggestive of latent tuberculesis.\u0000\u0000\u0000CONCLUSIONS\u0000Silica workers at the investigated industrial facility are at a significant risk of developing accelerated silicosis. Prevalence of infection with mycobacteria was high. Education of workers, improvement of protective measures and regular monitoring of the work environment should be undertaken to avert this deadly disease.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127111113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Growth hormone releasing hormone receptor codon 72 mutation in a cohort of Sri Lankan patients with growth hormone deficiency. 斯里兰卡生长激素缺乏症患者中生长激素释放激素受体密码子72突变

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/cmj.v61i1.8257

K. de Silva,, K. Tennekoon, T. Sundralingam, B. Navarathne, A. S. Hewage, W. De Silva, D. Ganihigama, H. D. Jayasinghe, M. Muhandiram

{"title":"Growth hormone releasing hormone receptor codon 72 mutation in a cohort of Sri Lankan patients with growth hormone deficiency.","authors":"K. de Silva,, K. Tennekoon, T. Sundralingam, B. Navarathne, A. S. Hewage, W. De Silva, D. Ganihigama, H. D. Jayasinghe, M. Muhandiram","doi":"10.4038/cmj.v61i1.8257","DOIUrl":"https://doi.org/10.4038/cmj.v61i1.8257","url":null,"abstract":"INTRODUCTION\u0000Growth hormone releasing hormone receptor (GHRH-R) codon 72 mutation is recognised as a common genetic cause of growth hormone deficiency (GHD) in the Indian subcontinent resulting in a characteristic lean phenotype. Genetic studies have not been previously carried out in Sri Lankans with GHD.\u0000\u0000\u0000METHODS\u0000Patients with GHD presenting to a tertiary care referral centre were studied for GHRH-R codon 72 mutation by PCR amplification and sequencing. The phenotype of the cohort was described as the BMI SDS (Body mass index standard deviation score) based on the anthropometric data at the time of diagnosis.\u0000\u0000\u0000RESULTS\u0000Among 91 patients from 88 families studied, eight (6 boys) carried the codon 72 mutation. The presence of this mutation was low among the Sinhalese ethnicity (3 out of 68) than among Tamil and Moor ethnicities. BMI SDS of <-2 was seen in 71% of mutation positive and 45.8% of mutation negative patients.\u0000\u0000\u0000CONCLUSIONS\u0000Prevalence of GHRH-R codon 72 mutation in this group of GH deficient patients was 8.8%. The lean phenotype observed in 71% of the mutation positive patients was not a significant association when compared to a similar phenotype in 45.8% of the mutation negative patients.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"243 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131930327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Immune response to hepatitis B vaccination in a group of medical students in Sri Lanka. 斯里兰卡一组医科学生对乙肝疫苗接种的免疫反应。

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/CMJ.V61I1.8267

Faseeha Noordeen, D. Madushanka, F. Pitchai

引用次数: 1

Reply: Takotsubo cardiomyopathy after an emotional outburst. 回复:情绪爆发后的Takotsubo心肌病。

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/cmj.v61i1.8266

J. Finsterer, M. Frank

引用次数: 0

Health benefits of Ceylon cinnamon (Cinnamomum zeylanicum): a summary of the current evidence. 锡兰肉桂(Cinnamomum zeylanicum)的健康益处:当前证据的总结。

The Ceylon medical journal Pub Date : 2016-03-21 DOI: 10.4038/cmj.v61i1.8251

P. Ranasinghe, P. Galappaththy