T. Dias, S. Abeykoon, S. Kumarasiri, C. Gunawardena, G. Pragasan, T. Padeniya, A. Pathmeswaran
{"title":"Symphysis-pubis fundal height charts to assess fetal size in women with a normal body mass index.","authors":"T. Dias, S. Abeykoon, S. Kumarasiri, C. Gunawardena, G. Pragasan, T. Padeniya, A. Pathmeswaran","doi":"10.4038/CMJ.V61I3.8345","DOIUrl":"https://doi.org/10.4038/CMJ.V61I3.8345","url":null,"abstract":"OBJECTIVES\u0000To construct symphysis-pubis fundal height (SFH) charts to estimate fetal size in pregnant women with a normal body mass index (BMI) and to describe the variation of SFH measurements according to BMI.\u0000\u0000\u0000METHODS\u0000cross sectional study was carried out at Ampara and Gampaha Districts in Sri Lanka. Women with normal nutritional and health status, normal BMI and minimal environmental constraints on fetal growth, with ultra sound confirmation of dates by fetal crown-rump length measurements between 11 weeks and 13 weeks + six days,had their SFH measured, using non-elastic tape and standard techniques, between 24 and 41 weeks gestation. Only one measurement of SFH was obtained from each pregnant woman. Linear and polynomial regression models were fitted separately to the means and standard deviations (SD) as functions of gestational age to identify the model with the best fit. Centiles were derived from the mean and SD at each gestational age.\u0000\u0000\u0000RESULTS\u0000Pregnant women from the districts of Ampara (n=387) and Gampaha (n=200) were recruited. Other than a difference of -1.5 cm (95% CI -2.27 to -0.23) at 38 weeks of gestation, there were no significant differences between the SFH measurements obtained from women with normal BMI in Ampara and Gampaha Districts. Using the SFH measurements from the Ampara sample, charts were created for 10th, 50th and 90th centile values of SFH. At 40 weeks of gestation these were 34 cm, 37 cm and 41 cm respectively. At 40 weeks gestation, the variation in SFH measurements between BMI sub groups within the normal range was approximately 1.4 cm to 1.6 cm.\u0000\u0000\u0000CONCLUSIONS\u0000These SFH charts could be used to estimate fetal size in pregnant women with normal BMI.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124986857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Senadheera, S. Sri Ranganathan, G. Patabendige, G. Fernando, D. Gamage, R M W Maneke, B. Fernandopulle
{"title":"Resistance and utilisation pattern of antibacterial agents in outpatient settings in two Teaching Hospitals in Colombo.","authors":"G. Senadheera, S. Sri Ranganathan, G. Patabendige, G. Fernando, D. Gamage, R M W Maneke, B. Fernandopulle","doi":"10.4038/CMJ.V61I3.8346","DOIUrl":"https://doi.org/10.4038/CMJ.V61I3.8346","url":null,"abstract":"OBJECTIVES\u0000Antibacterial resistance (ABR) is a public threat. Sri Lanka is a country with limited surveillance of ABR in the community. The WHO methodology was adapted to identify ABR in outpatient settings (nonhospitalised patients) and its link to consumption of antibiotics.\u0000\u0000\u0000METHODS\u0000It was a cross-sectional descriptive community based study to collect ABR data from Out Patient Department (OPD) of two leading Teaching Hospitals in Colombo district. The indicator organism Escherichia coli (E. coli) was obtained from the urine specimens of patients who were suspected to have urinary tract infections. Antibiotic susceptibility testing was performed for commonly used oral antibiotics using disc diffusion method. The antibiotic consumption aggregate data were collected from the OPD pharmacies of the said hospitals and expressed as Defined Daily Doses (DDD) per 1000 inhabitants per 1000 day.\u0000\u0000\u0000RESULTS\u0000Of the 2183 urine samples, pathogenic E. coli was isolated in 9.3% (204), and 8% (n=16) of them were Extended Spectrum Beta Lactamase (ESBL) producers. E.coli was most resistant to ampicillin (85%), followed by nalidixic acid (58.5%), trimethoprim/sulphamethoxazole (47.1%), ciprofloxacin (46.2%), norfloxacin (43.7%) amoxicillin /clavulanic acid (36.3%) and nitrofurantoin (15%). Multi-drug resistance was seen in 44%. Amoxicillin was the most frequently consumed antibacterial agent (2.65 DDD per 1000 inhabitants per day).\u0000\u0000\u0000CONCLUSIONS\u0000There is an alarmingly high antibiotic resistance in the non-hospitalised patients indicating high prevalence of E. coli resistance in the community.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127732946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Kumanan, M. Guruparan, K. Gnanakanthan, U. Ratnayake
{"title":"Interrupted Aortic Arch in an adult.","authors":"T. Kumanan, M. Guruparan, K. Gnanakanthan, U. Ratnayake","doi":"10.4038/CMJ.V61I3.8353","DOIUrl":"https://doi.org/10.4038/CMJ.V61I3.8353","url":null,"abstract":"Interrupted Aortic Arch (IAA) is an uncommon congenital anomaly representing approximately 1-2% of congenital heart disease. More than 97% of the cases have associated cardiac abnormalities, mainly VSD. The median age at death in untreated cases is four days making it rare to survive into adulthood without an associated structural cardiac abnormality. Here we report a patient with an IAA without any structural cardiac lesion who survived into third decade of his life.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117227165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Sanchayan, R. Fernandopulle, A. Amarasinghe, S. N. Thiyahiny, S. Sri Ranganathan
{"title":"Safety of live attenuated Japanese encephalitis vaccine given at the age of 9 months in National Immunisation Programme of Sri Lanka.","authors":"K. Sanchayan, R. Fernandopulle, A. Amarasinghe, S. N. Thiyahiny, S. Sri Ranganathan","doi":"10.4038/CMJ.V61I3.8344","DOIUrl":"https://doi.org/10.4038/CMJ.V61I3.8344","url":null,"abstract":"OBJECTIVES\u0000This study was designed to describe the safety profile of the single dose live attenuated Japanese encephalitis vaccine (LJEV) SA-14-14-2 given at the age of 9 months in the National Immunisation programme of Sri Lanka.\u0000\u0000\u0000METHODS\u0000cohort event monitoring (CEM) was conducted in the Jaffna district during November 2012 to January 2015. A representative sample of 3041 infants who received the LJEV at the age of 9 months was followed up actively over telephone interviews on days 1, 3, 14, 30 and 45 for adverse events (AE). Parents were encouraged to self-report in between these interviews. When an AE is notified, further clinical information was obtained through in-depth interviews and home/hospital visits to determine as an adverse event following immunisation (AEFI). Investigators independently reviewed each AEFI for consistent causal association with LJEV according to WHO causality assessment.\u0000\u0000\u0000RESULTS\u0000Of the 2878 (94%) infants who completed the follow up of 14 days, 911 (32%) experienced 1423 AEFIs. Of them, 376 (26%) were identified as AEFI with consistent causal association to LJEV (AEFIc). Irritability (53/ 1000 doses administered) and fever ≥100.4° F (46/1000 doses administered) accounted for 41% and 35% of AEFIcrespectively. Majority of AEFI (940) were identified as inconsistent as there were alternate causes. Nineteen AEFIc in 14 infants were classified as serious since they led to hospitalisation. Of the 2392 (79%) infants who completed 45 days follow up, 1022 experienced 1804 AEFI during 15-45 days. Only 20 were identified as AEFIc. There were no reported fatal or life threatening AEs.\u0000\u0000\u0000CONCLUSIONS\u0000LJEV administered to infants at 9 months was devoid of any significant safety concerns as most of the AEFIs were non-serious and resolved completely. CEM is a useful method for AEFI surveillance.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123962583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of idiopathic arterial calcification of infancy diagnosed at autopsy.","authors":"A. Dayapala, I L Rathnayake, P. Pethiyagoda","doi":"10.4038/CMJ.V61I3.8354","DOIUrl":"https://doi.org/10.4038/CMJ.V61I3.8354","url":null,"abstract":"Neonatal deaths pose challenges for parents, clinicians and forensic practitioners alike. Detailed histories, clinical and investigative findings, autopsies and ancillary investigations can be helpful in diagnosis. Even some rare genetic conditions can be diagnosed with commonly available diagnostic tools such as histology with Haematoxylin and Eosin staining. Once such inherited conditions are diagnosed, genetic counseling can be done to prevent recurrence of neonatal deaths. Idiopathic arterial calcification of infancy is an autosomal recessive condition characterised by calcification of internal elastic lamina of medium and large arteries causing sudden deaths in infancy [1-3].","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116079241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improvement of quality of speech in patients with velo-pharyngeal insufficiency corrected using a buccinator myomucosal flap.","authors":"D. K. Dias, P. Fernando, R. Dissanayake","doi":"10.4038/CMJ.V61I3.8349","DOIUrl":"https://doi.org/10.4038/CMJ.V61I3.8349","url":null,"abstract":"INTRODUCTION\u0000Oro-facial clefts involving the palate is the commonest structural defect causing velopharyngeal insufficiency (VPI) and poor intelli gibility of speech. Proper repair of the soft palateis a surgical challenge. Posterior-based buccinator myomucosal flap (BMF) is used to lengthen the soft palate of patients who undergo primary palatoplasty at Teaching Hospital, Karapitiya (THK). BMF is a good choice for the repair of medium sized mucosal defects in the oral cavity since it has appropriate thickness, contains mucous membrane with mucous glands and has a rich blood supply. Objectives To assess improvement in quality of speech after soft palate repair using BMF in patients with previously corrected cleft pate.\u0000\u0000\u0000METHODS\u0000Thirty four patients (M:F-1:1) who had undergone palatal lengthening using BMF procedure for correction of VPI for speech improvement at Teaching Hospital, Karapitiya from 2010 to 2012, were assessed before and one year after surgery for quality of speech.\u0000\u0000\u0000RESULTS\u0000All patients below 8 years showed significant reduction of hypernasality (p<0.05), whereas only 60% of patients above 8 years showed reduction after the surgery. All patients showed reduction in nasal air emission and in consonant production error at least by one consonant. The group below 8 years showed more improvement in speech quality after surgery.\u0000\u0000\u0000CONCLUSIONS\u0000Palatal lengthening using BMF procedure is a good treatment option for correction of VPI.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114836872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. B. F. Rahuman, J. Jayawardana, G. Francis, M. Niraj, A. T. Kumara, U. A. D. Wijesinghe, R. Haniffa, Ranithrie Ariyapperuma, C. Anuruddha, A. D. de Silva
{"title":"Outcome of early coronary intervention for acute ST elevation myocardial infarction in a tertiary care cardiac centre in Sri Lanka.","authors":"M. B. F. Rahuman, J. Jayawardana, G. Francis, M. Niraj, A. T. Kumara, U. A. D. Wijesinghe, R. Haniffa, Ranithrie Ariyapperuma, C. Anuruddha, A. D. de Silva","doi":"10.4038/cmj.v61i1.8258","DOIUrl":"https://doi.org/10.4038/cmj.v61i1.8258","url":null,"abstract":"OBJECTIVES\u0000To describe the outcomes of early percutaneous coronary intervention (PCI) for the treatment of acute ST elevation myocardial infarction (STEMI) in a tertiary care cardiac centre in Colombo, Sri Lanka.\u0000\u0000\u0000METHODS\u0000Medical records of 139 consecutive patients presenting to Cardiology Unit 5, National Hospital of Sri Lanka from March 2013 to June 2014 with acute STEMI, and treated with early PCI as a mode of reperfusion were reviewed. These patients were then followed up for 6 months to determine survival, target-vessel revascularization, in-stent thrombosis and other major adverse cardiac events (MACE).\u0000\u0000\u0000RESULTS\u0000Of 139 patients, 116 (83.5%) were male. Mean age was 52.3±SD11.1 years. Eighty eight (63.3%) patients underwent primary PCI and 51 (36.7%) underwent rescue PCI. There were six deaths (4.3%). One occurred on-table and three occurred after discharge. Four patients who died had cardiogenic shock. Mean door-to-balloon (DTB) time was 147 minutes for the primary PCI patients who were transferred from ETU. At six months, of 106 patients who attended follow up, two had been re-hospitalised for heart failure but none underwent coronary artery bypass grafting (CABG).\u0000\u0000\u0000CONCLUSIONS\u0000This report from the national tertiary care cardiology referral centre in Sri Lanka, found that the study population was relatively younger, similar to other Asian countries. There was high rate of initial success (98.6%) and good short-term survival (95.7%), particularly in the subset presenting without cardiogenic shock (98.4%) despite the long DTB time. Loss to follow up at 6 months in this centre was 23.7% (33 patients).","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128510340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Pathirana, K G M W Bandara, MA Faleel, S D Kuruppumullage, N. Solangarachchi, R. Rupasinghe, N P N Karunaratne, D D Ranasinghe, W. A. Epa, V. Thusyanthan
{"title":"A sonographic scoring system to assess the risk of thyroid malignancy.","authors":"A. Pathirana, K G M W Bandara, MA Faleel, S D Kuruppumullage, N. Solangarachchi, R. Rupasinghe, N P N Karunaratne, D D Ranasinghe, W. A. Epa, V. Thusyanthan","doi":"10.4038/cmj.v61i1.8268","DOIUrl":"https://doi.org/10.4038/cmj.v61i1.8268","url":null,"abstract":"Prediction of thyroid malignancy with fine needle aspiration cytology or individual ultrasound characteristics has several limitations. This study evaluates the usefulness of a combination of ultrasound characteristics in predicting malignancy in patients with thyroid nodules. We assessed 189 thyroid nodules using ultrasonography and histology. Each nodule was assigned a score based on ultrasonographic characteristics. This score was compared with histology to identify ability to predict malignancy. There were 28 malignant nodules. The scoring system was appropriate for clinical use, obtaining an area under ROC curve of 0.822 [p< 0.0001] 95% confidence. FNAC of nodules with a score of more than 4 can be recommended (100% sensitivity). Nodules with a score less than 8 can be offered total thyroidectomy when FNAC is inconclusive (97.5% sensitivity). A combination of ultrasonographic criteria increase the accuracy of predicting malignancy in thyroid nodules.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131958150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Galhenage, J. Rupasinghe, G. Abeywardena, A P De Silva, S. Williams, B. Gunasena
{"title":"Psychological morbidity and illness perception among patients receiving treatment for tuberculosis in a tertiary care centre in Sri Lanka.","authors":"J. Galhenage, J. Rupasinghe, G. Abeywardena, A P De Silva, S. Williams, B. Gunasena","doi":"10.4038/cmj.v61i1.8261","DOIUrl":"https://doi.org/10.4038/cmj.v61i1.8261","url":null,"abstract":"A descriptive cross sectional study was carried out to determine prevalence of depression and anxiety and to describe disease perception among patients with tuberculosis (TB) at National Hospital for Respiratory Diseases (NHRD), Welisara. Consecutive patients on anti-TB therapy admitted to wards and attending clinic were recruited until the estimated sample of 430 was reached. They were assessed using Hospital Anxiety and Depression Scale (HADS) and Brief Illness Perception Questionnaire (BIPQ). A total of 254 in-ward patients and 176 clinic patients were included. Of the inward patients, 25.2% had depression and 12.6% had anxiety. Of the clinic patients, 17.6% screened were positive for anxiety and 8.5% screened were positive for depression. Mean BIPQ score was 27.44 for the whole population. Prevalence of depression was significantly higher among in-ward patients (25.2%, p<0.0001), elderly age groups (20.5%, p=0.007), patients with lower education levels (20.6%, p= 0.012) and previously treated patients (32.3%, p=0.004). In-ward group (50.8%, p=0.002), lower education group (48.7%, p<0.0001), previously treated group (60%, p=0.005) and patients with depression (60.8%, p=0.001) and anxiety (68.3%, p<0.0001) showed significanly higher BIPQ scores. Our study shows that depression and anxiety are common among patients receiving treatment for TB.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129409634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W M S N Gunaratne, A T Wijeratne, S D Pilapitiya, S H Siribaddana
{"title":"A case of severe zinc phosphide poisoning.","authors":"W M S N Gunaratne, A T Wijeratne, S D Pilapitiya, S H Siribaddana","doi":"10.4038/cmj.v61i1.8263","DOIUrl":"https://doi.org/10.4038/cmj.v61i1.8263","url":null,"abstract":"","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125249419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}