European urology最新文献

{"title":"How Sound Are High-intensity Focused Ultrasound Data?","authors":"Nikos Grivas, Daniel Eberli, Henk van der Poel","doi":"10.1016/j.eururo.2024.12.013","DOIUrl":"https://doi.org/10.1016/j.eururo.2024.12.013","url":null,"abstract":"No Abstract","PeriodicalId":12223,"journal":{"name":"European urology","volume":"15 1","pages":""},"PeriodicalIF":23.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142935111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Jonas Hugosson. Population-based Screening for Prostate Cancer: Is It Time? Eur Urol. In press. https://doi.org/10.1016/j.eururo.2024.11.003","authors":"Renée C.A. Leenen, Monique J. Roobol, Katharina Beyer","doi":"10.1016/j.eururo.2024.12.012","DOIUrl":"https://doi.org/10.1016/j.eururo.2024.12.012","url":null,"abstract":"No Abstract","PeriodicalId":12223,"journal":{"name":"European urology","volume":"18 1 1","pages":""},"PeriodicalIF":23.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142925244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Cabozantinib Plus Nivolumab in Patients with Non–Clear Cell Renal Cell Carcinoma: Updated Results from a Phase II Trial” [Eur. Urol. 86(2) (2024) 90–94]","authors":"Kelly N. Fitzgerald , Chung-Han Lee , Martin H. Voss , Maria I. Carlo , Andrea Knezevic , Laura Peralta , Yingbei Chen , Robert A. Lefkowitz , Neil J. Shah , Colette N. Owens , Deaglan J. McHugh , David H. Aggen , Andrew L. Laccetti , Ritesh R. Kotecha , Darren R. Feldman , Robert J. Motzer","doi":"10.1016/j.eururo.2024.10.002","DOIUrl":"10.1016/j.eururo.2024.10.002","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"87 1","pages":"Page 96"},"PeriodicalIF":25.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142449845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Impact of Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography on Prostate Cancer Salvage Radiotherapy Management: Results from a Prospective Multicenter Randomized Phase 3 Trial (PSMA-SRT NCT03582774)” [Eur Urol. 86(1) (2024) 52–60]","authors":"Wesley R. Armstrong , Amar U. Kishan , Kiara M. Booker , Tristan R. Grogan , David Elashoff , Ethan C. Lam , Kevyn J. Clark , Michael L. Steinberg , Wolfgang P. Fendler , Thomas A. Hope , Nicholas G. Nickols , Johannes Czernin , Jeremie Calais","doi":"10.1016/j.eururo.2024.10.022","DOIUrl":"10.1016/j.eururo.2024.10.022","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"87 1","pages":"Pages 97-99"},"PeriodicalIF":25.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142597140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Long-term Prostate Cancer–specific Mortality After Prostatectomy, Brachytherapy, External Beam Radiation Therapy, Hormonal Therapy, or Monitoring for Localized Prostate Cancer","authors":"Francesco Montorsi , Mattia Longoni , Alberto Briganti , Giorgio Gandaglia","doi":"10.1016/j.eururo.2024.07.009","DOIUrl":"10.1016/j.eururo.2024.07.009","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"87 1","pages":"Pages 93-94"},"PeriodicalIF":25.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prostate Cancer Therapy Cardiotoxicity Map (PROXMAP) for Advanced Disease States: A Systematic Review and Network Meta-analysis with Bayesian Modeling of Treatment Histories","authors":"Moez Karim Aziz ,&nbsp;Donald Molony ,&nbsp;Dominique Monlezun ,&nbsp;Travis Holder ,&nbsp;Oliver Brunckhorst ,&nbsp;Noel Higgason ,&nbsp;Jerry Roland ,&nbsp;Resa Magill ,&nbsp;Mariya Fatakdawala ,&nbsp;Alexander Iacobucci ,&nbsp;Neal Mody-Bailey ,&nbsp;Chris Owen ,&nbsp;Andrew Zarker ,&nbsp;Emma Thames ,&nbsp;Justin Swaby ,&nbsp;Daniel Xiao ,&nbsp;Lily Choi ,&nbsp;Shubh Desai ,&nbsp;Jacob Galan ,&nbsp;Brett Deng ,&nbsp;Steven Canfield","doi":"10.1016/j.eururo.2024.08.031","DOIUrl":"10.1016/j.eururo.2024.08.031","url":null,"abstract":"<div><h3>Background and objective</h3><div>Recommendations of first-line therapies for metastatic hormone-sensitive (mHSPC), nonmetastatic castrate-resistant (M0CRPC), and metastatic castrate-resistant (mCRPC) prostate cancer do not account for cardiotoxicity due to a lack of clear prior evidence. This manuscript assesses cardiotoxicity of these therapies.</div></div><div><h3>Methods</h3><div>We searched Ovid Medline, Elsevier Embase, and the Cochrane Library for randomized clinical trials (RCTs) from database inception to January 14, 2024. Network meta-analyses of first-line mHSPC, M0CRPC, and mCRPC therapies were constructed for the five cardiotoxicity metrics defined by the International Cardio-Oncology Society: heart failure, myocarditis, vascular toxicity, hypertension, and arrhythmias. Additional Bayesian network meta-analyses also accounted for prior treatment history.</div></div><div><h3>Key findings and limitations</h3><div>Thirteen RCTs (16 292 patients) were included. For mHSPC, androgen deprivation therapy (ADT) plus docetaxel (DTX) plus abiraterone acetate (AA) with prednisone (P) demonstrated a significant increase in hypertension and arrhythmias versus ADT + DTX (risk ratio [RR] 2.85, 95% confidence interval [CI] 1.67–4.89, and RR 2.01, 95% CI 1.17–3.44, respectively); however, no corresponding differences were observed between ADT + DTX plus darolutamide (DAR) and ADT + DTX (RR 1.55, 95% CI 0.73–3.30, and RR 0.94, 95% CI 0.63–1.40, respectively). For mCRPC assuming a history of mHSPC treatment, ADT + AA + P plus olaparib (OLA) demonstrated a statistically significant decrease in hypertension versus ADT + AA + P (RR 0.20, 95% CI 0.16–0.26). M0CRPC results were unremarkable.</div></div><div><h3>Conclusions and clinical implications</h3><div>For mHSPC, ADT + DTX + DAR demonstrates less cardiotoxicity than ADT + DTX + AA + P due to a lower risk of hypertension and arrhythmias from decreased mineralocorticoid excess. In addition, OLA counterintuitively offers decreased hypertension when superimposed on ADT + AA + P for mCRPC treatment after prior androgen deprivation from mHSPC therapy.</div></div>","PeriodicalId":12223,"journal":{"name":"European urology","volume":"87 1","pages":"Pages 15-26"},"PeriodicalIF":25.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Niklas Klümper, Viktor Grünwald, Arndt Hartmann, et al. The Role of Microsatellite Instability/DNA Mismatch Repair Deficiency and Tumor Mutational Burden as Biomarkers in Predicting Response to Immunotherapy in Castration-resistant Prostate Cancer. Eur Urol. 2025;87:388–390","authors":"Feng Qi","doi":"10.1016/j.eururo.2024.08.037","DOIUrl":"10.1016/j.eururo.2024.08.037","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"87 1","pages":"Pages e15-e16"},"PeriodicalIF":25.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refining the Tissue Source for Biomarker-based Approaches in Renal Cell Carcinoma","authors":"Scott M. Haake,&nbsp;Brian I. Rini","doi":"10.1016/j.eururo.2024.09.029","DOIUrl":"10.1016/j.eururo.2024.09.029","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"87 1","pages":"Pages 84-85"},"PeriodicalIF":25.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standard Repeat Biopsies During Active Surveillance for Prostate Cancer: Are They Necessary in the Magnetic Resonance Imaging Era?","authors":"Roderick C.N. van den Bergh ,&nbsp;Ivo G. Schoots ,&nbsp;Philip A. Cornford ,&nbsp;European Association of Urology Prostate Cancer Guidelines Panel","doi":"10.1016/j.eururo.2024.09.014","DOIUrl":"10.1016/j.eururo.2024.09.014","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"87 1","pages":"Pages 5-7"},"PeriodicalIF":25.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management Decisions for Metastatic Castration-resistant Prostate Cancer in 2024","authors":"David J. VanderWeele,&nbsp;Maha Hussain","doi":"10.1016/j.eururo.2024.10.003","DOIUrl":"10.1016/j.eururo.2024.10.003","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"87 1","pages":"Pages 47-48"},"PeriodicalIF":25.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142450255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}