Facial Plastic SurgeryPub Date : 2025-04-01Epub Date: 2025-01-20DOI: 10.1055/a-2510-6807
Manoj T Abraham, John Wilson
{"title":"Exosomes in Facial Plastic Surgery.","authors":"Manoj T Abraham, John Wilson","doi":"10.1055/a-2510-6807","DOIUrl":"10.1055/a-2510-6807","url":null,"abstract":"<p><p>Exosomes have emerged as a promising therapeutic frontier in facial plastic surgery. Preclinical studies have demonstrated their ability to modulate wound healing, skin rejuvenation, hair growth, and nerve regeneration. Early clinical evidence suggests potential benefits in enhancing recovery after laser resurfacing, treating acne scars, and promoting hair growth. Despite their potential, there are currently no exosome products that are FDA-approved for medical use, and they should be considered experimental until receiving regulatory approval and robust clinical validation. As research advances, exosomes may offer valuable tools for facial plastic surgeons to improve patient outcomes and expand regenerative medicine applications in facial aesthetics and reconstruction.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"274-276"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selecting the Right Technique for the Treatment of Submental Adiposity.","authors":"Evan A Jones, Angela Sturm","doi":"10.1055/a-2559-7309","DOIUrl":"https://doi.org/10.1055/a-2559-7309","url":null,"abstract":"<p><p>This study focuses on interventions to improve the contour of the submentum. Various therapies for the submentum are available to the conscientious provider. To partner with patients effectively in today's aesthetic landscape, a provider must be well-versed in both surgical and minimally invasive techniques. This study aids decision-making and provides therapeutic options for a diverse patient population.Given the wide array of options for treating the submentum, this study differentiates based on invasiveness. Transcutaneous therapies include cryolipolysis, ultrasound, microwave, and laser. Percutaneous treatments include Kybella or enzymatic mixture injection and transcutaneous energy delivery. Liposuction with or without adjunctive treatments and deep neck lifts are the subcutaneous and structural options.Submental interventions, whether percutaneous, transcutaneous, or subcutaneous, amplify the natural characteristics and beauty of the patient. Aligning the proper technique with the proper patient is the mark of a perceptive surgeon who accounts for underlying anatomy and treatment goals.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Margareta Morrissette, Alexandra Michalowski, Anthony P Sclafani
{"title":"Factors Contributing to Burnout and Professional Fulfillment among AAFPRS Members.","authors":"Margareta Morrissette, Alexandra Michalowski, Anthony P Sclafani","doi":"10.1055/a-2558-7975","DOIUrl":"10.1055/a-2558-7975","url":null,"abstract":"<p><p>Physician wellness is important for physician engagement and reduction of medical errors 1-6, impacting patient care. A recent survey showed that academic otorhinolaryngologists reported low levels of professional fulfillment and high levels of burnout 7,8. This study explores wellness factors in facial plastic and reconstructive surgery (FPRS).To examine factors associated with fulfillment, burnout, and intent to leave within FPRS.Cross-sectional survey.AAFPRS members completed an anonymous and standardized survey to assess professional fulfillment and burnout. Chi-square testing was used for data analysis.Among 75 respondents (5% response rate), 34% lacked professional fulfillment and 18% experienced burnout, lower than reported rates in academic otorhinolaryngology7. Lack of decision-making power in recruitment/purchasing decisions and uncompensated otolaryngology call were driving factors.Decreased autonomy and extra-subspecialty responsibilities drive burnout, lack of fulfillment, and intent to leave and should be considered in employment arrangements.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Bogari, Mohammed Jomah, Naif Alshehri, Hamad F Alrabiah, Abdullah Binghaith, Khalid AlOsaimi, Lulu Aldhwaihy, Alaa Baghazal, Hassan Bogari
{"title":"5-Fluorouracil in Facial Plastic Surgery: Indications, Efficacy, and Safety - A Systematic Review and Narrative Synthesis.","authors":"Ahmad Bogari, Mohammed Jomah, Naif Alshehri, Hamad F Alrabiah, Abdullah Binghaith, Khalid AlOsaimi, Lulu Aldhwaihy, Alaa Baghazal, Hassan Bogari","doi":"10.1055/a-2541-2644","DOIUrl":"10.1055/a-2541-2644","url":null,"abstract":"<p><p>5-Fluorouracil (5-FU) is an antimetabolite that inhibits fibroblast proliferation and collagen synthesis, making it valuable in facial plastic surgery for scar modulation and other conditions. This systematic review examines the indications, outcomes, and safety of 5-FU in facial plastic surgery. Due to methodological heterogeneity across studies, a narrative synthesis was performed. A comprehensive search of MEDLINE, Cochrane, SCOPUS, EMBASE, PubMed, and Web of Science identified 32 eligible studies (1,456 patients) from 4,772 screened articles. Indications included keloids, hypertrophic scars, contractures, periocular scars, granulomas from filler complications, nasal skin thickening, infections following thread lifts, resistant facial warts, and hypochromic lesions. Most studies reported reductions in scar size, erythema, and recurrence rates, with combination therapies enhancing outcomes. Adverse effects were mild and transient. However, variability in dosing, administration frequency, and follow-up underscores the need for standardized treatment guidelines and long-term studies.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andre Generalow, Milos Kovacevic, Theresia Stigger, Barbara Kofler
{"title":"Angulated Cephalic Strip Flap in Lateral Crura Reduction: A Scroll Area Preservation Technique in Rhinoplasty.","authors":"Andre Generalow, Milos Kovacevic, Theresia Stigger, Barbara Kofler","doi":"10.1055/a-2541-2708","DOIUrl":"10.1055/a-2541-2708","url":null,"abstract":"<p><p>In nasal tip surgery, achieving both functional and aesthetic results is crucial. Several complications, such as alar retraction or weakening of the internal nasal valve (INV), are associated with the \"classical\" cephalic trim. To prevent complications in nasal tip surgery a horizontal reduction of the lateral crus (LC) using a cephalic hinged flap while preserving the scroll area is described. In 138 patients with bulbous tips, a modification of the hinged flap, the angulated cephalic strip flap (ACSF), was performed during open septorhinoplasty. The cephalic portion of the lower lateral cartilage was superficially incised without separation, preserving the scroll area. The anterior-cephalic triangle of the cephalic portion was resected to facilitate tip sutures and avoid cartilage duplication in the new dome area and hereby creation of additional, undesired volume. The cephalic part was folded inferiorly and anchored with a single fixation suture. Additionally, a fixation with a suture in the scroll area should be performed to strengthen the cranial border of the LC to prevent flap displacement and warping of lower lateral cartilage, particularly in thin-skin patients where the healing forces are significantly stronger. In all 138 patients, a satisfactory postoperative result was achieved, with improved aesthetic and functional outcomes for the nasal tip. The ACSF facilitated tip suturing in all patients after resection of the anterior-cephalic triangle. No revision related to this technique was required, and no narrowing of the INV was observed.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
İbrahim Ömer Gürlek, Filiz Gülüstan, Burak Kaan İnan, Ahmet Bahadır Göktaş, Öznur İnan, İbrahim Sayın, Kamil Hakan Kaya
{"title":"Nonsurgical Rhinoplasty: Histopathological Effects of Dermal Fillers on Nasal Cartilage in a Rabbit Model.","authors":"İbrahim Ömer Gürlek, Filiz Gülüstan, Burak Kaan İnan, Ahmet Bahadır Göktaş, Öznur İnan, İbrahim Sayın, Kamil Hakan Kaya","doi":"10.1055/a-2541-2508","DOIUrl":"10.1055/a-2541-2508","url":null,"abstract":"<p><p>Nonsurgical rhinoplasty has emerged as a preferred nasal aesthetic treatment due to its safety, predictability, and high patient satisfaction. It utilizes dermal fillers, primarily hyaluronic acid (HA), to enhance nasal profiles and correct defects. However, limited data exist on the effects of HA-containing dermal fillers on nasal cartilage. This study aimed to evaluate these effects histopathologically. Sixteen New Zealand white rabbits were divided into two groups (A and B). Group A's right lateral cartilages (AR) received 0.1 mL of VYC-20L filler, while the left (AL) received isotonic saline. Group B's right lateral cartilages (BR) received 0.1 mL of VYC-25L filler, with the left (BL) serving as the control. After 90 days, the rabbits were sacrificed, and cartilage samples were analyzed histopathologically for cartilage thickness, chondrocyte nucleus loss, inflammation, fibrosis, giant cells, granulation tissue, abscess, and necrosis. Statistical significance was set at <i>p</i> < 0.05. Significant differences were found between groups for chondrocyte nucleus loss, fibrosis, and giant cells (<i>p</i> = 0.005, 0.018, <0.001, respectively). No difference was observed in cartilage thickness between AR and BR (<i>p</i> = 0.918). Chondrocyte nucleus loss was present in AR and BR but absent in AL and BL. Giant cells were detected in all VYC-20L and VYC-25L samples. Chronic inflammation and fibrosis varied but were not statistically significant. No abscess or necrosis was observed. This study demonstrated the histopathological effects of VYC-20L and VYC-25L on nasal cartilage using a rabbit model. Further studies with larger samples and diverse fillers are recommended.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Facial Fillers and Surgical Rhinoplasty: Cross-Sectional Study.","authors":"Géraldine Vansteelant, Alwyn D'Souza","doi":"10.1055/a-2535-0108","DOIUrl":"https://doi.org/10.1055/a-2535-0108","url":null,"abstract":"<p><p>This study aims to provide an overview of how rhinoplasty surgeons manage patients with previous nonsurgical rhinoplasty and facial fillers. A multicenter international cross-sectional study was conducted in accordance with strengthening the reporting of observational studies in epidemiology (STROBE) guidelines. A survey was distributed to members of the European Academy of Facial Plastic Surgery and associated colleagues, with responses analyzed from surgeons performing over 10 rhinoplasties annually. A total of 171 surgeons from 45 countries participated, with 165 meeting the inclusion criteria. The respondents included ear, nose, and throat (41%), plastic (7%), maxillo-facial (10%), and facial plastic surgeons (23%), averaging 116 rhinoplasties annually and 13 years of experience. Among the surgeons, 74% perform rhinoplasty on patients with prior nasal fillers, typically waiting 21 weeks after filler rhinoplasty before surgery. Additionally, 44% of surgeons remove nasal fillers preoperatively, primarily using hyaluronidase. During surgery, 76% of surgeons remove nasal fillers, and 25% modify their surgical steps for patients with a history of fillers. This study shows that there is no clear consensus in the management of patients with nasal fillers. Surgeons are often unaware of the preoperative existence of nasal and facial fillers, their potential complications, and their management. To address this, guidelines should be established to facilitate the management of the growing number of patients with facial fillers.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alfonso Luca Pendolino, Bruno Scarpa, Peter J Andrews
{"title":"The Effectiveness of Functional Septorhinoplasty in Improving COVID-19-related Olfactory Dysfunction.","authors":"Alfonso Luca Pendolino, Bruno Scarpa, Peter J Andrews","doi":"10.1055/a-2535-0153","DOIUrl":"10.1055/a-2535-0153","url":null,"abstract":"<p><p>Long-Term COVID-19-related olfactory dysfunction (C19OD) remains a significant challenge with no established treatment providing meaningful improvement. This study aimed to assess the efficacy of functional septorhinoplasty (fSRP) in improving olfactory dysfunction in patients with persistent C19OD compared to a control group undergoing olfactory training (OT). In this prospective study patients with persistent C19OD undergoing fSRP were enrolled while those declining surgery continued with OT as the control group. Patients were followed for six months with olfactory function assessed using Sniffin' Sticks (S'S) and nasal airflow evaluated through peak nasal inspiratory flow (PNIF) and acoustic rhinometry (AR). Among the participants 12 underwent fSRP while 13 were in the control group. Significant improvements (p < 0.05) in all S'S scores were observed in the fSRP group but not in the control group. TDI scores improved above the minimal clinically important difference only in the fSRP group. Strong correlations were found between olfactory scores and nasal measurements. Comparison of olfactory threshold gains between groups revealed a statistically significant benefit in the fSRP group. These findings suggest that fSRP can significantly improve persistent C19OD providing a notable olfactory threshold gain compared to OT.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Edema, Ecchymosis, and Pain: Classic versus Electric Micro-Saw Osteotomy.","authors":"Erdem Bayrakci, Mitat Aricigil, M Akif Eryilmaz, Fakih Cihat Eravci, Hamdi Arbağ","doi":"10.1055/a-2528-4172","DOIUrl":"https://doi.org/10.1055/a-2528-4172","url":null,"abstract":"<p><p>To compare postoperative edema, ecchymosis, and pain after rhinoplasty using conventional (classical) osteotomy versus powered (electric) micro-saw osteotomy techniques. Between December 2021 and May 2023, 90 patients aged 18 to 45 underwent rhinoplasty at our clinic. Of these, 45 patients underwent lateral and transverse osteotomy with powered saw instruments, whereas 45 underwent conventional osteotomy. A resident examined edema, ecchymosis, and pain on the first, third, and seventh postoperative days. The specialist was blinded to the osteotomy method (single-blind). Edema and ecchymosis were categorized using the Yücel modification of the Kara and Gokalan classification, and the pain was evaluated using the visual analog scale. The patients who underwent osteotomy with an electric micro-saw (group 1) had less edema on the first and third days than with conventional osteotomy (group 2). However, on the seventh day, although group 1 had slightly less edema than group 2, there were no significant differences. On the other hand, group 2 had significantly more ecchymosis on the first and third postoperative days compared with group 1, but there were no significant differences on the seventh day. On the first postoperative days, patients in group 2 reported significantly more pain on average compared with group 1. There were no significant differences in pain levels between the two groups on the third and seventh days following the surgery. After rhinoplasty, patients commonly suffer from edema, ecchymosis, and pain. Our research suggests that using a powered micro-saw effectively reduces early-stage ecchymosis and pain compared with the conventional low-to-low osteotomy technique. However, there were no notable differences between the two methods regarding edema, ecchymosis, and pain on the seventh day after surgery. The electric micro-saw appears to be a feasible alternative in the osteotomy step, showing effectiveness comparable to that of the conventional method.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro P Villarroel, Cristobal Langdon, Diego Arancibia-Tagle
{"title":"Improving Postsurgical Management of Rhinoplasty: A Comprehensive Review of Existing Literature.","authors":"Pedro P Villarroel, Cristobal Langdon, Diego Arancibia-Tagle","doi":"10.1055/a-2533-2651","DOIUrl":"10.1055/a-2533-2651","url":null,"abstract":"<p><p>Rhinoseptoplasty addresses both nasal deformities and functional issues. Effective postoperative care is essential for optimal recovery, as complications such as swelling, bruising, and pain can adversely affect healing and patient satisfaction. Proper postoperative care emphasizes the significance of comprehensive management strategies.A systematic literature review was performed utilizing the PubMed and Cochrane databases to identify articles published between 2014 and 2024 that specifically addressed postoperative care following rhinoplasty. Of 191 articles, 22 met the preestablished inclusion criteria. We assessed the quality of evidence according to the Oxford Centre for Evidence-Based Medicine's Levels of Evidence.Seven key studies were analyzed, exploring a range of postoperative care interventions, including administering corticosteroids, elevating the head during and after the procedure, using alternative therapeutic approaches, and applying cooling techniques.Postsurgical recovery after rhinoplasty involves managing pain, swelling, and bruising, among other complications. Educating patients about expected outcomes and the healing process helps alleviate their anxiety and uncertainty. Corticosteroids have proven effective in controlling swelling and bruising. Antibiotics are generally not recommended. Silicone septal splints provide support, particularly when stabilization of an injured mucous membrane or septal cartilage is required; however, nasal packing is not recommended. Adhesive strips can help reduce edema in the dorsal and supratip areas. Positioning patients in a 20° reverse Trendelenburg position during surgery, followed by maintaining the head elevated at a 90° angle postoperatively, has significantly reduced edema and ecchymosis. Using a cannula for drainage and cooling techniques has been shown to reduce postoperative morbidity effectively.Rhinoplasty is a common facial plastic surgery, yet there is no consensus on optimal postoperative care. Key strategies include silicone splints, subperiosteal drainage, nasal taping, cooling, corticosteroids, and intra- and postoperative head elevation. However, further systematic trials are necessary to refine these strategies and improve patient outcomes.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}