Cryolipolysis for Submental Fat Reduction: A Systematic Review and Meta-Analysis.

IF 1.1 4区医学 Q3 SURGERY

Facial Plastic Surgery Pub Date : 2025-06-05 DOI:10.1055/a-2628-3831

Kenny Do, Nabih Ghani, Nathan Lloyd, Emily S Sagalow, Kurtis Young, Benjamin Tam, Sisi Tian, Harry H Ching, Jo-Lawrence Bigcas

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引用次数: 0

Abstract

Introduction: Submental fat can be addressed using both surgical and non-surgical techniques. Cryolipolysis is a non-invasive treatment that uses cold temperatures to trigger apoptosis in adipose tissue. Objectives & Hypotheses: This study aims to evaluate the efficacy and safety of cryolipolysis for submental fat reduction, specifically analyzing changes in submental fat thickness and volume. It is hypothesized that cryolipolysis leads to measurable improvements in submental fat among patients.

Study design: This is a systematic review and meta-analysis conducted in accordance with the PRISMA reporting guidelines.

Methods: A literature search was performed across PubMed, Scopus, and Web of Science from 1973 to 2025. A total of 951 articles were screened, and eight pre-post studies involving 206 patients met inclusion criteria.

Results: Pooled analysis showed a mean reduction in submental fat thickness of -2.78 mm and volume of -19.57 cm³.

Conclusion: Cryolipolysis significantly reduces submental fat with minimal, transient side effects.

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冷冻脂肪分解减少颏下脂肪：系统回顾和荟萃分析。

引言：颏下脂肪可以通过手术和非手术技术来解决。低温脂肪分解是一种非侵入性治疗，使用低温触发脂肪组织的细胞凋亡。目的与假设：本研究旨在评价冷冻脂肪溶解术减少颏下脂肪的有效性和安全性，特别是分析颏下脂肪厚度和体积的变化。据推测，冷冻脂肪溶解可显著改善患者的精神下脂肪。研究设计：这是一项按照PRISMA报告指南进行的系统综述和荟萃分析。方法：检索1973 - 2025年PubMed、Scopus和Web of Science的文献。共有951篇文章被筛选，8项涉及206名患者的前后研究符合纳入标准。结果：合并分析显示，颏下脂肪厚度平均减少-2.78 mm，体积平均减少-19.57 cm³。结论：冷冻脂肪溶解术可显著减少颏下脂肪，且副作用极小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Facial Plastic Surgery 医学-外科

CiteScore

1.80

自引率

10.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Facial Plastic Surgery is a journal that publishes topic-specific issues covering areas of aesthetic and reconstructive plastic surgery as it relates to the head, neck, and face. The journal''s scope includes issues devoted to scar revision, periorbital and mid-face rejuvenation, facial trauma, facial implants, rhinoplasty, neck reconstruction, cleft palate, face lifts, as well as various other emerging minimally invasive procedures. Authors provide a global perspective on each topic, critically evaluate recent works in the field, and apply it to clinical practice.