{"title":"Global Research Trends in Surgical Management of Facial Paralysis: A Bibliometric Analysis.","authors":"Yaliang Yang, Zheng Zhang, Yuan Peng, Can Zhang","doi":"10.1055/a-2969-4686","DOIUrl":"10.1055/a-2969-4686","url":null,"abstract":"<p><strong>Introduction: </strong>The surgical treatment strategies of facial paralysis are diversified, and the existing research lacks systematic integration of global research trends and core hotspots.</p><p><strong>Objectives and hypotheses: </strong>The purpose of this study is to sort out the research status, hotspots, and development trends of surgical treatment of facial paralysis worldwide from 2015 to 2025 through bibliometric analysis, so as to provide reference for future research.</p><p><strong>Study design: </strong>This is a bibliometric analysis.</p><p><strong>Methods: </strong>Literatures related to the surgical treatment of facial paralysis were retrieved from the Web of Science Core Collection, and bibliometric analysis was performed using CiteSpace software.</p><p><strong>Results: </strong>A total of 240 publications were included. The annual publication output showed a steady increase. China, the United States, and Italy were the leading contributing countries. The most prolific institutions included Harvard Medical School, the University of Milan, and the University of Toronto. Keywords and cluster analysis showed that the research hotspots focused on facial nerve decompression, nerve transfer, functional free muscle transplantation, selective neurotomy, and facial dynamic reconstruction. Emerging trends include dual innervation techniques, neurovascular free flaps, and the integration of electromyographic feedback and artificial intelligence in surgical planning.</p><p><strong>Conclusion: </strong>The surgical treatment of facial paralysis is an area of continuous dynamic development, with increasing emphasis on functional recovery and individualized treatment strategies. Strengthening international cooperation and multidisciplinary integration is crucial for future progress. The results of this study can serve as a reference for future research directions and clinical practice.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2025-12-29DOI: 10.1055/a-2778-9712
David Ulrich Seidel, Nicole Rotter, Mark Scheithauer, Olaf Ebeling, Simon Bode
{"title":"Advances in Rhinoplasty Evidence: A Narrative Overview of Recent Meta-analyses (2015-2025).","authors":"David Ulrich Seidel, Nicole Rotter, Mark Scheithauer, Olaf Ebeling, Simon Bode","doi":"10.1055/a-2778-9712","DOIUrl":"10.1055/a-2778-9712","url":null,"abstract":"<p><strong>Introduction: </strong>Septoplasty and septorhinoplasty are key procedures in functional and aesthetic nasal surgery. Over the past decade, evidence on diagnostics, techniques, and outcomes has expanded significantly.</p><p><strong>Objectives: </strong>To provide a structured summary of current evidence from systematic reviews and meta-analyses, focusing on diagnostics, surgical techniques, perioperative treatment, and patient-reported outcomes.</p><p><strong>Study design: </strong>Narrative review of 86 articles, reviews, and meta-analyses published within the past 10 years.</p><p><strong>Methods: </strong>Studies were screened for relevance to functional and aesthetic rhinoplasty. Extracted data covered diagnostic methods, surgical techniques, medications, PROMs, and functional outcomes.</p><p><strong>Results: </strong>Four-phase rhinomanometry offers promise but lacks validation. Body dysmorphic disorder (BDD) screening is gaining relevance. Evidence supports perioperative corticosteroids and tranexamic acid; routine antibiotics appear unnecessary. PROMs (NOSE, ROE, SNOT-22) are widely used.</p><p><strong>Conclusion: </strong>Evidence for rhinoplasty is growing but heterogeneous. Standardized diagnostics, PROM-linked objective measures, and long-term data are needed to guide future patient-centered care.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"640-651"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145855118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2026-06-04DOI: 10.1055/a-2883-0757
Robert B Baldwin, Brandon J Dyer, Luka Bedalov, Julia Toman
{"title":"The Role of Anti-Inflammatory Nutrition in Facial Cosmetic Surgery Outcomes: A Scoping Review.","authors":"Robert B Baldwin, Brandon J Dyer, Luka Bedalov, Julia Toman","doi":"10.1055/a-2883-0757","DOIUrl":"10.1055/a-2883-0757","url":null,"abstract":"<p><strong>Introduction: </strong>Prolonged inflammatory responses are associated with impaired wound healing, increased surgical complications, and poor health outcomes. Additionally, anti-inflammatory diet and nutrition have been shown to reduce harmful inflammatory markers in the body. However, the relationship between anti-inflammatory diet and surgical outcomes remains poorly understood in cosmetic surgery populations.</p><p><strong>Objectives and hypotheses: </strong>This scoping review aims to evaluate the quality and quantity of the current literature regarding the impact of the anti-inflammatory diet on facial cosmetic surgery outcomes.</p><p><strong>Study design: </strong>Scoping Review following PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines.</p><p><strong>Methods: </strong>A literature search was performed in PubMed, Embase, Scopus, and CINAHL with keywords relating to anti-inflammatory diet, surgical outcomes, and elective surgery. Duplicate articles were removed, and the remaining were reviewed by two independent reviewers. Inclusion criteria consisted of studies with elective surgery patients, immunomodulating nutritional interventions, and outcomes relating to facial cosmetic surgery. Exclusion criteria included studies focused on gastrointestinal surgery, oncological surgery, emergent surgery, total parenteral nutrition, or malnourished populations. Additionally, we excluded systematic reviews, commentaries, editorials, abstracts, non-English studies, and protocols.</p><p><strong>Results: </strong>Our literature search yielded 2,954 articles, of which 36 articles underwent full-text review, and 7 studies met inclusion criteria. There was substantial variability in surgeries performed, study quality, specialties covered, outcome measures, and interventions. Three studies reported clinical outcomes such as wound complications or postoperative morbidity, whereas the remaining four studies focused on immune cell recovery and inflammatory markers. Importantly, multiple studies demonstrated statistically significant improvements in length of hospital stay, inflammatory markers, or complication rates. Unfortunately, no studies evaluated facial cosmetic surgery directly.</p><p><strong>Conclusion: </strong>While the evidence is extremely limited, anti-inflammatory nutrition shows promise in modulating factors that are related to cosmetic surgery outcomes. These findings suggest that anti-inflammatory diets and nutrition for cosmetic surgery patients warrant further investigation.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"563-570"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2026-05-05DOI: 10.1055/a-2849-8666
Sam Lam
{"title":"Micro Botulinum Toxin Techniques.","authors":"Sam Lam","doi":"10.1055/a-2849-8666","DOIUrl":"10.1055/a-2849-8666","url":null,"abstract":"<p><strong>Aim and background: </strong>To introduce micro botulinum toxin therapy (MBT) for the treatment of aging skin, scarring, and other skin therapies.</p><p><strong>Historical aspects: </strong>Mesotherapy involved the injection of microdoses of vitamins and nutrients, and serves as the backdrop for this current intervention.</p><p><strong>Anatomy: </strong>MBT is advocated to work on improving both epidermal and dermal damage through cellular repair induced by dilute botulinum toxin (BT).</p><p><strong>Technology: </strong>The technique does not require any sophisticated technology to perform other than a syringe loaded with dilute BT.</p><p><strong>Patient selection: </strong>Patients of all Fitzpatricks and ages are eligible for therapy without risk other than rare, temporary paresis.</p><p><strong>Techniques: </strong>The technique involves injection of hyperdilute BT intradermally across the entire expanse of the face, neck, chest, etc., to effect desired skin changes.</p><p><strong>Postoperative care: </strong>None.</p><p><strong>Current and future development: </strong>Other ingredients could be added to further enhance the efficacy of MBT.</p><p><strong>Conclusion and clinical relevance: </strong>MBT offers unparalleled safety and efficacy in all skin types for a variety of skin improvements, including active acne, acne scarring, pores, texture, and generalized cutaneous sun damage and aging.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"597-600"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147835736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2026-06-30DOI: 10.1055/a-2898-5952
Margareta Morrissette, Eli Stein, Katherine Tai, Oscar Trujillo
{"title":"In-Office Surgical Procedures for Prejuvenation.","authors":"Margareta Morrissette, Eli Stein, Katherine Tai, Oscar Trujillo","doi":"10.1055/a-2898-5952","DOIUrl":"10.1055/a-2898-5952","url":null,"abstract":"<p><strong>Aims and backgrounds: </strong>This review describes surgical interventions that address structural and anatomical changes in younger patients with the aim of delaying traditional rejuvenating or corrective surgery in an operative setting.</p><p><strong>Historical aspects: </strong>Traditionally, surgical procedures like submentoplasty and rhytidectomy are used to rejuvenate and/or correct anatomical, structural, and/or age-related defects in patients with advanced aging.</p><p><strong>Anatomy: </strong>For appropriate younger patients, we describe a shift away from cutaneous, surface-level changes to procedures aimed to correct structural changes resulting from aging, trauma, or genetic manifestation, specifically addressing submental fat, plastysmal diastasis, jowling, and periorbital dermatochalasis.</p><p><strong>Patient selection: </strong>Candidates are younger patients with high skin elasticity and mild structural changes.</p><p><strong>Techniques: </strong>Targeted procedures include submentoplasty, mini-facelift, and preservation-focused upper and lower blepharoplasty performed in the office, under local anesthesia for younger patients.</p><p><strong>Postoperative care: </strong>Emphasis is placed on compression, cold therapy, and supplements to minimize downtime and swelling.</p><p><strong>Conclusion and clinical relevance: </strong>In appropriate patients, the surgical, structural prejuvenation techniques described herein offer a proactive, durable result from procedures performed entirely in-office.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"614-621"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148360212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2026-05-25DOI: 10.1055/a-2875-0254
Mallory Rose Layne, Jessica Ann Weiser
{"title":"The Safety and Efficacy of At-Home Devices for Skin Care.","authors":"Mallory Rose Layne, Jessica Ann Weiser","doi":"10.1055/a-2875-0254","DOIUrl":"10.1055/a-2875-0254","url":null,"abstract":"<p><strong>Aim and background: </strong>At-home skin care devices have gained significant popularity as consumers seek convenient, noninvasive treatments for common dermatologic concerns. These devices are designed to address issues such as early signs of aging, acne, and skin dullness while maintaining a favorable safety profile for unsupervised consumer use.</p><p><strong>Technology: </strong>Common technologies used in at-home devices include light-emitting diode therapy, radiofrequency, microcurrent, low-energy laser, and intense pulsed light. Compared with professional in-office treatments, these devices operate at lower energy outputs and incorporate safety mechanisms to reduce the risk of burns, dyspigmentation, and scarring. Many devices are cleared by the U.S. Food and Drug Administration, indicating that they meet established safety standards when used according to manufacturer instructions.</p><p><strong>Current and future development: </strong>Evidence from small clinical studies suggests that at-home devices may stimulate collagen production, reduce acne lesions, and improve overall skin texture. However, clinical outcomes are generally more gradual and less pronounced than those achieved with professional-grade equipment due to lower treatment intensity.</p><p><strong>Conclusion and clinical relevance: </strong>At-home skin care devices demonstrate a favorable safety profile and modest clinical efficacy for maintenance therapy and early dermatologic intervention when used appropriately.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"571-578"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148014194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2026-06-15DOI: 10.1055/a-2894-5802
Michael T Somenek
{"title":"Biostimulatory Injectables for Collagen Stimulation.","authors":"Michael T Somenek","doi":"10.1055/a-2894-5802","DOIUrl":"10.1055/a-2894-5802","url":null,"abstract":"<p><strong>Aim and background: </strong>Biostimulatory injectables represent a transformative paradigm in aesthetic medicine, shifting the therapeutic focus from immediate volumization to biologically driven tissue regeneration. Unlike traditional hyaluronic acid fillers, agents such as calcium hydroxylapatite (CaHA) and poly-L-lactic acid (PLLA) harness the body's endogenous regenerative capacity by activating fibroblasts and promoting neocollagenesis. This chapter reviews the scientific foundations, mechanisms of action, clinical applications, and evolving role of these two principal biostimulatory agents.</p><p><strong>Anatomy: </strong>CaHA and PLLA exert their regenerative effects primarily within the dermis and subdermal connective tissue. Optimal outcomes require a precise injection technique within the subdermal plane, and treatment zones include the face, neck, décolletage, and body.</p><p><strong>Technology: </strong>CaHA microspheres provide immediate structural support while simultaneously functioning as a biologic scaffold for neocollagenesis. PLLA microparticles achieve their regenerative effect through gradual polymer hydrolysis and prolonged fibroblast stimulation, yielding cumulative and durable improvements across staged treatment sessions.</p><p><strong>Techniques: </strong>Both PLLA and Hyperdilute CaHA formulations enable versatile treatment across multiple anatomic regions. Optimal outcomes depend on proper patient selection, appropriate dilution strategies, and precise injection technique within the subdermal plane.</p><p><strong>Post operative care: </strong>Thorough patient counseling regarding the delayed onset of results is essential to manage expectations. PLLA, in particular, requires staged treatment sessions to achieve cumulative improvements.</p><p><strong>Conclusion and clinical relevance: </strong>Together, CaHA and PLLA offer clinicians a sophisticated, biologically grounded complement to the broader injectable armamentarium, addressing the underlying structural causes of facial aging rather than solely masking their clinical manifestations.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"601-606"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148257814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2026-04-13DOI: 10.1055/a-2849-8783
Naina Tanya Judge
{"title":"New Technology in Skin and Facial Analysis: Elevating the Clinical Encounter for Patients and Providers.","authors":"Naina Tanya Judge","doi":"10.1055/a-2849-8783","DOIUrl":"10.1055/a-2849-8783","url":null,"abstract":"<p><strong>Aim and background: </strong>Aesthetic medicine has expanded rapidly, yet the clinical infrastructure supporting the patient encounter has not kept pace with patient sophistication. Today's aesthetic patient is highly educated, visually literate, and accustomed to data-driven decision-making. A measurable gap exists between patient expectations and what the standard clinical encounter consistently delivers.</p><p><strong>Technology: </strong>This review examines emerging technologies in skin and facial analysis and presents the evidence-based case for their adoption across the full care continuum. Technologies are organized by clinical function: in-office multispectral skin analysis systems, three-dimensional (3D) volumetric imaging and simulation platforms, AI facial scoring and proportion analysis tools, and advanced tissue characterization modalities.</p><p><strong>Patient selection: </strong>A three-phase framework-preconsultation, consultation, and posttreatment-structures the case for adoption. Patient selection considerations, informed consent implications, and the appropriate boundaries of AI-assisted analysis versus clinical diagnostic judgment are addressed.</p><p><strong>Conclusion and clinical relevance: </strong>Technology-augmented encounters produce better-informed patients, stronger clinical trust, and more defensible outcomes. Technology does not replace the surgeon-patient relationship-it amplifies it.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"556-562"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2026-04-15DOI: 10.1055/a-2854-6601
David Liao, Aman Prasad, Jason D Bloom
{"title":"Use of Ultrasound in Face and Neck Rejuvenation.","authors":"David Liao, Aman Prasad, Jason D Bloom","doi":"10.1055/a-2854-6601","DOIUrl":"10.1055/a-2854-6601","url":null,"abstract":"<p><strong>Aim and background: </strong>To review the current state of ultrasound energy-based devices and their role in facial and neck rejuvenation.</p><p><strong>Historical aspects: </strong>High-frequency ultrasound (HIFU) paved the way for the micro-focused and parallel beam ultrasound technology in aesthetics.</p><p><strong>Anatomy: </strong>Facial and cervical aging reflect multilayered structural changes, as well as reduced collagen production and increased collagen breakdown at the histologic level, resulting in rhytids and skin laxity.</p><p><strong>Technology: </strong>Micro-focused ultrasound with visualization (MFU-V) is adapted from HIFU, using significantly less ultrasound energy and visualization to precisely target the deep dermis and superficial musculoaponeurotic system (SMAS) at depths ranging from 1.5 to 4.5 mm; synchronous ultrasound parallel beam (SUPERB) technology uses parallel transducers to deliver energy at a precise depth of 1.5 mm to target the mid-dermis.</p><p><strong>Patient selection: </strong>Ultrasonic facial rejuvenation is ideal for those with mild to moderate skin laxity who desire incremental tightening and textural improvement without surgery.</p><p><strong>Techniques: </strong>MFU-V can be performed at different tissue depths based on the transducer tip, with various combination protocols described; SUPERB technology delivers energy at a fixed depth.</p><p><strong>Postoperative care: </strong>Self-limited erythema and edema, sun protection.</p><p><strong>Current and future development: </strong>The intersection of ultrasonic devices and regenerative medicine is promising.</p><p><strong>Conclusion and clinical relevance: </strong>MFU-V and SUPERB are ideal noninvasive options for patients with mild to moderate skin laxity.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"607-613"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147688855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Facial Plastic SurgeryPub Date : 2026-10-01Epub Date: 2026-06-12DOI: 10.1055/a-2887-9735
Benjamin C Paul
{"title":"Non-Surgical Hair Restoration Options: Current Techniques and Emerging Technologies in Prejuvenation.","authors":"Benjamin C Paul","doi":"10.1055/a-2887-9735","DOIUrl":"10.1055/a-2887-9735","url":null,"abstract":"<p><strong>Aims and backgrounds: </strong>Hair loss is a highly prevalent condition, and patients are increasingly seeking prejuvenation and restoration. This review evaluates contemporary non-surgical hair restoration modalities.</p><p><strong>Historical aspects: </strong>Therapeutic strategies have evolved from topical vasodilators to targeted hormonal, regenerative, and device-based interventions reflecting advances in our understanding of follicular biology and technology.</p><p><strong>Anatomy: </strong>Hair follicle cycling is regulated by dermal papilla signaling, epithelial stem cells, and perifollicular vascular and inflammatory environments.</p><p><strong>Technology: </strong>Non-surgical therapies include oral and topical pharmacologics, hormonal therapies, platelet-rich plasma (PRP), microneedling, peptide-based treatments, exososomes, nutraceuticals, low-level laser (light) therapy (LLLT), lasers, and transdermal delivery systems.</p><p><strong>Patient selection: </strong>Appropriate candidates include patients with androgenetic alopecia and other non-scarring alopecias; accurate diagnosis is critical.</p><p><strong>Techniques: </strong>Combination therapy is increasingly utilized to target multiple biologic pathways.</p><p><strong>Post operative care: </strong>Minimal downtime is expected; long-term adherence is required.</p><p><strong>Current and future development: </strong>Emerging therapies include exosome-based treatments, peptides, and advanced drug delivery platforms.</p><p><strong>Conclusion and clinical relevance: </strong>Non-surgical modalities are central to prejuvenation and can delay or complement surgical intervention when appropriately applied.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"584-590"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148239158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}