European Psychiatry最新文献

{"title":"Mental disorders into adulthood among adolescents placed in residential care: A prospective 10-year follow-up study - CORRIGENDUM.","authors":"Süheyla Seker, Cyril Boonmann, Delfine d'Huart, David Bürgin, Klaus Schmeck, Nils Jenkel, Martin Steppan, Alexander Grob, Hilma Forsman, Jörg M Fegert, Marc Schmid","doi":"10.1192/j.eurpsy.2025.22","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.22","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"68 1","pages":"e52"},"PeriodicalIF":7.2,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12041730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical restraint in inpatient psychiatric settings: a systematic review of international prevalence, associations, outcomes and reduction strategies.","authors":"Daniel Whiting, Alexandra Lewis, Kursoom Khan, Eddie Alder, Gill Gookey, John Tully","doi":"10.1192/j.eurpsy.2025.2453","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.2453","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-35"},"PeriodicalIF":7.2,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health status of the European population and its determinants: a cross-national comparison study.","authors":"Javier-David Lopez-Morinigo, Andrea Fiorillo, Geert Dom, Celso Arango","doi":"10.1192/j.eurpsy.2025.2449","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.2449","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-27"},"PeriodicalIF":7.2,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prefrontal cortex stimulation prevents stress-induced HPA axis reactivity in people at familial risk of schizophrenia.","authors":"Ondine Adam, Mélanie Perret, Louis Simon, Clément Dondé, Véronique Raverot, William Vallet, Marine Mondino, Jérôme Brunelin","doi":"10.1192/j.eurpsy.2025.2455","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.2455","url":null,"abstract":"<p><strong>Background: </strong>Schizophrenia is a multifactorial disorder with a range of risk factors. Dysregulation in the systems involved in the stress response is a key component of its pathophysiology. Individuals at risk of developing schizophrenia exhibit hyperreactivity to stress and altered cognitive performance, both known as vulnerability markers. This study aims to determine whether stimulation of the prefrontal cortex can reduce reactivity to stress in unaffected siblings of patients with schizophrenia.</p><p><strong>Methods: </strong>In a randomized, sham-controlled trial, 27 participants were assigned to receive either active (<i>n</i> = 14) or sham (<i>n</i> = 13) transcranial direct current stimulation (tDCS) over the prefrontal cortex for 30 min during exposure to an acute stressor. The stress response was measured biologically, via salivary cortisol levels, and cognitively, through a reality monitoring task, which serves as an intermediate cognitive vulnerability marker.</p><p><strong>Results: </strong>In contrast to the sham condition, active stimulation significantly reduced cortisol release in response to stress (<i>F</i>_(9,216) = 1.972; <i>p</i> = 0.04) and prevented stress-induced impairment in reality monitoring (<i>F</i>_(1,23) = 9.954; <i>p</i> = 0.004).</p><p><strong>Conclusions: </strong>These findings suggest that tDCS should be a promising tool for reducing stress-induced biological and cognitive reactivity in a population at risk of schizophrenia.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"68 1","pages":"e55"},"PeriodicalIF":7.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Profiles before Suicide Mortality in Patients with Bipolar Disorder across the Lifespan.","authors":"Yueh-Pin Lin, Wen-Yin Chen, Chun-Hung Pan, Sheng-Siang Su, Shang-Ying Tsai, Chiao-Chicy Chen, Chian-Jue Kuo","doi":"10.1192/j.eurpsy.2025.2451","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.2451","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-32"},"PeriodicalIF":7.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosing ADHD in adults in randomized controlled studies: A scoping review.","authors":"Igor Studart, Mads Gram Henriksen, Julie Nordgaard","doi":"10.1192/j.eurpsy.2025.2447","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.2447","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-23"},"PeriodicalIF":7.2,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Responsiveness of European countries to the population mental health needs: a cross-national comparison study.","authors":"Celso Arango, Andrea Fiorillo, Geert Dom, Javier-David Lopez-Morinigo","doi":"10.1192/j.eurpsy.2025.2448","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.2448","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-29"},"PeriodicalIF":7.2,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in adults with Attention-Deficit/Hyperactivity Disorder: A population-based study.","authors":"Ferran Mestres, Vanesa Richarte, Juan Jesús Crespín, Carla Torrent, Santiago Biel, Carolina Ramos, Pol Ibáñez, Laura Oltra-Arañó, Montse Corrales, Silvia Amoretti, Christian Fadeuilhe, Josep Antoni Ramos-Quiroga","doi":"10.1192/j.eurpsy.2025.2441","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.2441","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-29"},"PeriodicalIF":7.2,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A network approach to lifestyle behaviors and health outcomes in people with mental illness: the MULTI+ study III.","authors":"Natascha M den Bleijker, Myrthe M E van Schothorst, Tessa F Blanken, Ingrid J M Hendriksen, Wiepke Cahn, Jeroen Deenik","doi":"10.1192/j.eurpsy.2025.2442","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.2442","url":null,"abstract":"<p><strong>Background: </strong>Unhealthy lifestyle behaviors are prevalent among people with mental illness (MI), affecting their physical and mental health. Most research has focused on the isolated effects of lifestyle behaviors, leaving the interconnectedness between these behaviors and health outcomes unexplored. This study aimed to examine these relationships and identify the most strongly connected lifestyle behavior or health outcome within a network.</p><p><strong>Methods: </strong>We conducted a cross-sectional study with 423 inpatients with MI, receiving care as usual. Lifestyle behaviors, physical and mental health outcomes were assessed through questionnaires and routine data. A Gaussian Graphical Model was estimated, and strength centrality was calculated to identify the most influential nodes.</p><p><strong>Results: </strong>Mean age was 55.5 years, 42% were female, and 41% were diagnosed with schizophrenia. Psychological and physical quality of life (QoL), nighttime sleep problems, and overall sleep quality were the most strongly connected nodes. Sleep was strongly associated with physical QoL. Furthermore, there were negative associations between healthy food intake and cholesterol ratio, and positive associations between daily doses of antipsychotics and length of hospital stay. Node strength was stable (CS(cor = 0.7) = 0.75). No clear pattern emerged among other lifestyle behaviors and health outcomes.</p><p><strong>Conclusions: </strong>This study offers insights into the interrelatedness of lifestyle behaviors and health outcomes. Addressing sleep problems could enhance QoL and potentially influence other health outcomes. Psychological and physical QoL were also strongly associated, emphasizing the importance of perceived well-being in health outcomes. Future research could explore causal pathways to identify treatment targets to improve care.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"68 1","pages":"e53"},"PeriodicalIF":7.2,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12041728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of scopolamine on memory and attention: a systematic review and meta-analysis.","authors":"Cerena Miravalles, Dara M Cannon, Brian Hallahan","doi":"10.1192/j.eurpsy.2025.2446","DOIUrl":"10.1192/j.eurpsy.2025.2446","url":null,"abstract":"<p><strong>Background: </strong>Scopolamine is a muscarinic receptor antagonist and is widely utilized as a \"memory-loss model.\" However, its impact across different memory and attention tasks and using different modes of administration has yet to be clearly evaluated. This systematic review and meta-analysis investigates the effect of scopolamine, across all routes of administration and across different dosages, on memory and attention performance in healthy humans (PROSPERO ID: CRD42024531634).</p><p><strong>Methods: </strong>Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we searched (on 20 April 2024) for studies that utilized scopolamine and assessed memory and/or attention. Random-effects meta-analyses were conducted across a range of memory and attention tasks using \"Comprehensive Meta-Analysis,\" Version 3, to evaluate differential pharmacological effects on cognitive tasks between the scopolamine and placebo groups.</p><p><strong>Results: </strong>Forty-six studies fulfilled the inclusion and exclusion criteria. Scopolamine negatively impaired performance on all memory tasks (immediate memory, delayed recall, digit span, Buschke selective reminding task, and recognition memory) and led to slower reaction times for three of the five attention tasks examined (choice reaction time, simple reaction time, and rapid visual information processing) compared to placebo. Scopolamine's negative effect on memory and attention was greater with injectable (e.g., intramuscular, intravenous, and subcutaneous) compared to non-injectable routes of administration (e.g., intranasal, oral, and transdermal).</p><p><strong>Conclusion: </strong>This study supports the use of scopolamine as a \"memory-loss model,\" particularly when given by an injectable route of administration. Future clinical trials should evaluate the bioavailability of scopolamine across different routes of administration to ensure therapeutic benefits outweigh any potential adverse cognitive effects.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"e50"},"PeriodicalIF":7.2,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12041729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}