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The future of diagnosis in mental health: promises and challenges of biomarkers to identify reliable and highly predictive biosignatures of affective disorders.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-02-06 DOI: 10.1192/j.eurpsy.2025.15
Alessandra Berry, Mario Luciano, Francesca Cirulli, Andrea Fiorillo
{"title":"The future of diagnosis in mental health: promises and challenges of biomarkers to identify reliable and highly predictive biosignatures of affective disorders.","authors":"Alessandra Berry, Mario Luciano, Francesca Cirulli, Andrea Fiorillo","doi":"10.1192/j.eurpsy.2025.15","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.15","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-6"},"PeriodicalIF":7.2,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep-administered ketamine/psychedelics: A streamlined strategy to address two challenges in research on ketamine and psychedelics. 睡眠管理氯胺酮/迷幻剂：解决氯胺酮和迷幻药研究两大难题的简化策略。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-02-05 DOI: 10.1192/j.eurpsy.2025.14
Shokouh Arjmand, Mats B Lindström, Carl M Sellgren, Gregers Wegener
{"title":"Sleep-administered ketamine/psychedelics: A streamlined strategy to address two challenges in research on ketamine and psychedelics.","authors":"Shokouh Arjmand, Mats B Lindström, Carl M Sellgren, Gregers Wegener","doi":"10.1192/j.eurpsy.2025.14","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.14","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-5"},"PeriodicalIF":7.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Respiratory disease in people with Major Depressive Disorder: A Systematic Review and Meta-analysis.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-02-05 DOI: 10.1192/j.eurpsy.2025.13
Ana Jiménez-Peinado, David Laguna-Muñoz, María José Jaén-Moreno, Cristina Camacho-Rodríguez, Gloria Isabel Del Pozo, Eduard Vieta, Javier Caballero-Villarraso, Fernando Rico-Villademoros, Fernando Sarramea
{"title":"Respiratory disease in people with Major Depressive Disorder: A Systematic Review and Meta-analysis.","authors":"Ana Jiménez-Peinado, David Laguna-Muñoz, María José Jaén-Moreno, Cristina Camacho-Rodríguez, Gloria Isabel Del Pozo, Eduard Vieta, Javier Caballero-Villarraso, Fernando Rico-Villademoros, Fernando Sarramea","doi":"10.1192/j.eurpsy.2025.13","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.13","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-34"},"PeriodicalIF":7.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuropsychiatric adverse events associated with Glucagon-like peptide-1 receptor agonists: a pharmacovigilance analysis of the FDA Adverse Event Reporting System database.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-02-04 DOI: 10.1192/j.eurpsy.2024.1803
Wenchao Lu, Shihan Wang, Huilin Tang, Tao Yuan, Wei Zuo, Yuling Liu
{"title":"Neuropsychiatric adverse events associated with Glucagon-like peptide-1 receptor agonists: a pharmacovigilance analysis of the FDA Adverse Event Reporting System database.","authors":"Wenchao Lu, Shihan Wang, Huilin Tang, Tao Yuan, Wei Zuo, Yuling Liu","doi":"10.1192/j.eurpsy.2024.1803","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2024.1803","url":null,"abstract":"<p><strong>Background: </strong>Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used due to their profound efficacy in glycemic control and weight management. Real-world observations have revealed potential neuropsychiatric adverse events (AEs) associated with GLP-1RAs. This study aimed to comprehensively investigate and characterize these neuropsychiatric AEs with GLP-1RAs.</p><p><strong>Methods: </strong>We analyzed GLP-1RA adverse reaction reports using the FDA Adverse Event Reporting System database. Disproportionality analysis using reporting odds ratio (ROR) identified eight categories of neuropsychiatric AEs associated with GLP-1RAs. We conducted descriptive and time-to-onset (TTO) analyses and explored neuropsychiatric AE signals among individual GLP-1RAs for weight loss and diabetes mellitus (DM) indications.</p><p><strong>Results: </strong>We identified 25,110 cases of GLP-1RA-related neuropsychiatric AEs. GLP-1RAs showed an association with headache (ROR 1.74, 95% confidence interval [CI] 1.65-1.84), migraine (ROR 1.28, 95%CI 1.06-1.55), and olfactory and sensory nerve abnormalities (ROR 2.44, 95%CI 1.83-3.25; ROR 1.69, 95%CI 1.54-1.85). Semaglutide showed a moderate suicide-related AEs signal in the weight loss population (ROR 2.55, 95%CI 1.97-3.31). The median TTO was 16 days (interquartile range: 3-66 days).</p><p><strong>Conclusions: </strong>In this study, we identified eight potential neuropsychiatric adverse events (AEs) associated with GLP-1RAs and, for the first time, detected positive signals for migraine, olfactory abnormalities, and sensory abnormalities. We also observed positive suicide-related signals of semaglutide, in weight loss population. This study provides a reliable basis for further investigation of GLP-1RA-related neuropsychiatric AEs. However, as an exploratory study, our findings require confirmation through large-scale prospective studies.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"68 1","pages":"e20"},"PeriodicalIF":7.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between antidepressants and risk of suicidal behaviour and violent crimes in personality disorder.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-02-03 DOI: 10.1192/j.eurpsy.2025.16
Kimmo Herttua, Giulio Scola, Tapio Paljarvi, Seena Fazel
{"title":"Associations between antidepressants and risk of suicidal behaviour and violent crimes in personality disorder.","authors":"Kimmo Herttua, Giulio Scola, Tapio Paljarvi, Seena Fazel","doi":"10.1192/j.eurpsy.2025.16","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.16","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-28"},"PeriodicalIF":7.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing the EPA Guidance of Pharmacological Treatment of Schizophrenia - Results of a Delphi process.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-30 DOI: 10.1192/j.eurpsy.2024.1794
Peter Falkai, Elias Wagner, Miriam John, Vladislav Yakimov, Silvana Galderisi, Istvan Bitter, Geert Dom, Andrea Schmitt, Wolfgang Gaebel, Bernardo Carpiniello, Alkomiet Hasan
{"title":"Developing the EPA Guidance of Pharmacological Treatment of Schizophrenia - Results of a Delphi process.","authors":"Peter Falkai, Elias Wagner, Miriam John, Vladislav Yakimov, Silvana Galderisi, Istvan Bitter, Geert Dom, Andrea Schmitt, Wolfgang Gaebel, Bernardo Carpiniello, Alkomiet Hasan","doi":"10.1192/j.eurpsy.2024.1794","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2024.1794","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-24"},"PeriodicalIF":7.2,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of social distancing on mental health during the Covid-19 pandemic: A nationwide study of 4.6 million Danish adults.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-28 DOI: 10.1192/j.eurpsy.2025.5
Andreas Geest, Barbara Bonnesen, Alexander Jordan, Louise Tønnesen, Valdemar Rømer, Charlotte S Ulrik, Zitta Barrella Harboe, Josefin Eklöf, Pradeesh Sivapalan, Jens-Ulrik Stæhr Jensen
{"title":"The impact of social distancing on mental health during the Covid-19 pandemic: A nationwide study of 4.6 million Danish adults.","authors":"Andreas Geest, Barbara Bonnesen, Alexander Jordan, Louise Tønnesen, Valdemar Rømer, Charlotte S Ulrik, Zitta Barrella Harboe, Josefin Eklöf, Pradeesh Sivapalan, Jens-Ulrik Stæhr Jensen","doi":"10.1192/j.eurpsy.2025.5","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.5","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-24"},"PeriodicalIF":7.2,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
European Psychiatry: 2024 in review.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-27 DOI: 10.1192/j.eurpsy.2025.4
Sophia Frangou, Andrea Fiorillo
{"title":"European Psychiatry: 2024 in review.","authors":"Sophia Frangou, Andrea Fiorillo","doi":"10.1192/j.eurpsy.2025.4","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.4","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-7"},"PeriodicalIF":7.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between IL-6 and trajectories of depressive symptoms across the life course: Evidence from ALSPAC and UK Biobank cohorts.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-27 DOI: 10.1192/j.eurpsy.2025.7
A J Edmondson-Stait, E Davyson, X Shen, M J Adams, G M Khandaker, V E Miron, A M McIntosh, S M Lawrie, A S F Kwong, H C Whalley
{"title":"Associations between IL-6 and trajectories of depressive symptoms across the life course: Evidence from ALSPAC and UK Biobank cohorts.","authors":"A J Edmondson-Stait, E Davyson, X Shen, M J Adams, G M Khandaker, V E Miron, A M McIntosh, S M Lawrie, A S F Kwong, H C Whalley","doi":"10.1192/j.eurpsy.2025.7","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.7","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-54"},"PeriodicalIF":7.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HOW TO IMPROVE PSYCHIATRIC NOSOGRAPHY IN THE XXI CENTURY: A PHENOMENOLOGIST'S VIEWPOINT.
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-27 DOI: 10.1192/j.eurpsy.2025.11
Giovanni Stanghellini
{"title":"HOW TO IMPROVE PSYCHIATRIC NOSOGRAPHY IN THE XXI CENTURY: A PHENOMENOLOGIST'S VIEWPOINT.","authors":"Giovanni Stanghellini","doi":"10.1192/j.eurpsy.2025.11","DOIUrl":"https://doi.org/10.1192/j.eurpsy.2025.11","url":null,"abstract":"","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"1-10"},"PeriodicalIF":7.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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