Food Additives & Contaminants: Part A最新文献_第7页

Exposure to nitrate from food and drinking-water in New Zealand. Can these be considered separately? 在新西兰，人们从食物和饮用水中接触硝酸盐。这些可以分开考虑吗?

Food Additives & Contaminants: Part A Pub Date : 2022-03-18 DOI: 10.1080/19440049.2022.2037725

P. Cressey, B. Cridge

{"title":"Exposure to nitrate from food and drinking-water in New Zealand. Can these be considered separately?","authors":"P. Cressey, B. Cridge","doi":"10.1080/19440049.2022.2037725","DOIUrl":"https://doi.org/10.1080/19440049.2022.2037725","url":null,"abstract":"Abstract Recent epidemiological studies have reported associations between colorectal cancer incidence and nitrates in drinking-water, but not from the diet. The toxicokinetics of nitrates were reviewed and exposure data from New Zealand were analysed. Dietary (including drinking-water) exposure of New Zealanders to nitrates was found to be very similar to most other countries and within internationally-established acceptable daily intakes. Less than 10% of nitrate exposure was from drinking-water, with little difference between adults and children. Approximately half of the total water-based exposure is through water alone, the remainder was consumed as tea and coffee (adults), or water-based fruit drinks (children). For children, drinking-water as a beverage is generally consumed close to a meal time, with 83% of servings consumed within an hour of eating. For adults, this is reduced to 51% of servings consumed within an hour of a meal. Only 2.6% of nitrate exposure for adults and 0.7% of nitrate exposure for children is from drinking-water consumed on its own and not in close temporal association to food consumption. It was concluded from the combination of the biology and the exposure assessment that there is little reason to differentiate between drinking-water and food nitrate exposure.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"23 1","pages":"838 - 852"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79328008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The effect of high hydrostatic pressure on tetracycline hydrochloride and sulfathiazole residues in various food matrices – comparison with ultrasound and heat treatment 高静水压力对各种食品基质中盐酸四环素和磺胺噻唑残留的影响——与超声和热处理的比较

Food Additives & Contaminants: Part A Pub Date : 2022-03-18 DOI: 10.1080/19440049.2022.2036820

Nikolaos D Sidirokastritis, Ioannis Tsiantoulas, C. Tananaki, P. Vareltzis

{"title":"The effect of high hydrostatic pressure on tetracycline hydrochloride and sulfathiazole residues in various food matrices – comparison with ultrasound and heat treatment","authors":"Nikolaos D Sidirokastritis, Ioannis Tsiantoulas, C. Tananaki, P. Vareltzis","doi":"10.1080/19440049.2022.2036820","DOIUrl":"https://doi.org/10.1080/19440049.2022.2036820","url":null,"abstract":"Abstract Antibiotic residues in food pose serious direct and indirect risks for consumers. The aim of this study was to investigate the effect of High Hydrostatic Pressure (HHP) on tetracycline hydrochloride (TCH) and sulfathiazole (STZ) residues in honey, milk, and water. Three different pressures were tested for their efficiency and treatment at 580 MPa for 6 min was finally selected. Qualitative and quantitative determination of antibiotics were performed with HPLC and LC-MS. HHP treatment was compared to ultrasound and heat treatment. HHP treatment was found to be more effective than the other two methods for both antibiotics in water and milk. The reduction of STZ in honey was over 90%, while no reduction was observed for TCH. The highest TCH reduction was recorded after HHP treatment in water (76.4%) and the highest STZ reduction after ultrasound treatment in honey (94.3%). Reduction of the two antibiotics in different matrices did not follow a similar pattern. For the HHP treatment, the effect of the initial concentration of the two antibiotics was studied under two different storage conditions (refrigerated and frozen storage). The effectiveness of the method was found to be affected by the initial concentration, in both storage conditions for STZ, while for TCH significant differences were observed only for refrigerated storage.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"165 1","pages":"687 - 698"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75059211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Scopolamine and atropine in feeds – determination with liquid chromatography mass spectrometry 饲料中的东莨菪碱和阿托品。液相色谱-质谱法测定

Food Additives & Contaminants: Part A Pub Date : 2022-03-18 DOI: 10.1080/19440049.2022.2037724

E. Kowalczyk, K. Kwiatek

引用次数: 5

Risk characterization of dietary acrylamide exposure and associated factors in the Portuguese population 葡萄牙人群饮食丙烯酰胺暴露的风险特征及相关因素

Food Additives & Contaminants: Part A Pub Date : 2022-03-14 DOI: 10.1080/19440049.2022.2047540

S. Costa, D. Correia, Catarina Carvalho, S. Vilela, M. Severo, C. Lopes, D. Torres

{"title":"Risk characterization of dietary acrylamide exposure and associated factors in the Portuguese population","authors":"S. Costa, D. Correia, Catarina Carvalho, S. Vilela, M. Severo, C. Lopes, D. Torres","doi":"10.1080/19440049.2022.2047540","DOIUrl":"https://doi.org/10.1080/19440049.2022.2047540","url":null,"abstract":"Abstract Acrylamide exposure, mainly resulting from food cooking and processing, has been associated with a higher risk of health problems, due to genotoxic effects. This study aims to estimate acrylamide dietary exposure of the Portuguese population and its associated factors. Dietary data collected through 2 non-consecutive 24 hour recalls or food diaries from a representative sample of the Portuguese population from the National Food, Nutrition and Physical Activity Survey was used (n = 5811; 3–84 years). Occurrence data of acrylamide in food were obtained from EFSA. The margins of exposure (MOE) were calculated for peripheral neuropathy and neoplastic effects. The association between acrylamide and socio-demographic characteristics was estimated through linear regression models. For the total population, the estimated median daily dietary exposure per body weight to acrylamide was 0.38 µg/kg/day, ranging from 0.14 to 0.88 µg/kg/day for the 5th and 95th percentile, respectively. Children aged between 1–2 years had the highest acrylamide exposure (median 0.75 µg/kg/day, 95th percentile 1.41 µg/kg/day). For the peripheral neuropathy and neoplastic effects, the median MOE estimated was 1140 and 451, respectively. Men compared to women had a higher acrylamide dietary exposure, as well as smokers compared to non-smokers. Elderly and less educated individuals were inversely associated with acrylamide exposure. ‘Bread and rusks’ (24.2%) were the main source of acrylamide, followed by ‘coffee’ (21.3%). The current dietary exposure to acrylamide in the Portuguese population is of concern mainly regarding neoplastic effects. Our results point to the need to reduce exposure to acrylamide, especially in men, young children, higher educated individuals and smokers.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"44 1","pages":"888 - 900"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79633720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Acrylamide in widely consumed foods – a review 广泛食用食品中的丙烯酰胺——综述

Food Additives & Contaminants: Part A Pub Date : 2022-03-14 DOI: 10.1080/19440049.2022.2046292

Francesca Pietropaoli, Sara Pantalone, A. Cichelli, N. d’Alessandro

引用次数: 8

Application of the maximum cumulative ratio (MCR) as a screening tool for the evaluation of multiple metal mixtures in shellfish in Chinese population 应用最大累积比(MCR)筛选中国人群贝类中多种金属混合物

Food Additives & Contaminants: Part A Pub Date : 2022-03-14 DOI: 10.1080/19440049.2022.2037726

W. Mao, Ding-guo Jiang, Haixia Sui, Yan Song, Yiting Shao, Lei Zhang

{"title":"Application of the maximum cumulative ratio (MCR) as a screening tool for the evaluation of multiple metal mixtures in shellfish in Chinese population","authors":"W. Mao, Ding-guo Jiang, Haixia Sui, Yan Song, Yiting Shao, Lei Zhang","doi":"10.1080/19440049.2022.2037726","DOIUrl":"https://doi.org/10.1080/19440049.2022.2037726","url":null,"abstract":"Abstract The objective of this study was to investigate the potential effects from exposure to multiple metals, including cadmium (Cd), chromium (Cr), arsenic (As), mercury (Hg), nickel (Ni) and lead (Pb) that exist in shellfish in Chinese populations, and evaluate the impacts of cumulative exposures among individuals. A total 15,469 individual shellfish samples were analyzed following a protocol for elemental analysis. A total of 25,669 respondents were selected through stratified multi-stage cluster sampling from 31 survey sites in China. Individual shellfish consumption data and body weight were collected and analyzed with a 24-hour dietary recall method on three non-consecutive days. The consumers were divided into two groups: aged 2–12 years group and aged ≥13 years. Exposure levels were estimated based using a semi-probabilistic risk assessment method and cumulative exposures among individual persons using the maximum cumulative ratio (MCR) method. The mean, median and 95th percentile of all metals exposure for age 2–12 years group were higher than age ≥13 years group, but none exceeded the respective reference doses of the metals. The mean hazard indices (HI) of each metal in shellfish for both age groups were less than 1. The MCR values calculated among 1283 consumers ranged from 1.28 to 3.25 with the average MCR value was 2.22. There were 51 (3.98%) consumers in group I, 1186 (92.44%) consumers in group II, 26(2.03%) consumers in group III A, and 20 (1.56%) consumers in group III B. And cadmium (Cd) and lead (Pb) produced the HQMax that trigged cumulative exposures. It was concluded that heavy metals did not present a potential health risk to people solely through shellfish. The cumulative risks indicated that 7.56% of the surveyed consumers were of concern because of high HI of metals exposure, and Cd, Pb, and Ni made significant contributions to the potential risk. Graphical Abstract","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"167 1","pages":"938 - 948"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73498618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Dissipation characteristics of spirotetramat and its metabolites in two phenotypically different Korean vegetables under greenhouse conditions 温室条件下两种表型不同的高丽蔬菜中螺虫及其代谢物的耗散特性

Food Additives & Contaminants: Part A Pub Date : 2022-03-14 DOI: 10.1080/19440049.2022.2046293

Rakhi Nandi, Se-Yeon Kwak, Sang-Hyeob Lee, A. Sarker, Hyo-Jeong Kim, Dong-Ju Lee, Y. Heo, K. Kyung, J. Kim

{"title":"Dissipation characteristics of spirotetramat and its metabolites in two phenotypically different Korean vegetables under greenhouse conditions","authors":"Rakhi Nandi, Se-Yeon Kwak, Sang-Hyeob Lee, A. Sarker, Hyo-Jeong Kim, Dong-Ju Lee, Y. Heo, K. Kyung, J. Kim","doi":"10.1080/19440049.2022.2046293","DOIUrl":"https://doi.org/10.1080/19440049.2022.2046293","url":null,"abstract":"Abstract This study involved analysis and method validation of spirotetramat applied to two phenotypically different Korean vegetables (e.g. Korean cabbage and shallots) to determine the safe pre-harvest residue limit (PHRL) and comparative dissipation patterns. Two steps of the investigation involved greenhouse monitoring during crop cultivation followed by LC-MS/MS analysis. Commercial spirotetramat was sprayed twice with seven-day intervals according to the spray schedule (0, 3, 7, 10, 14, and 21 days before harvest) at the dose recommended by the Ministry of Food and Drug Safety (MFDS), Korea. During the validation of the analytical method, good linearity, specificity, and acceptable recoveries (82%–114% for Korean cabbage and 82%–111% for shallot) were established for spirotetramat and its four metabolites. The calculated biological half-life derived from the first-order reaction (t1/2) of spirotetramat was 4.8 days for Korean cabbage and 4.0 days for shallot, respectively. The safe PHRL for Korean cabbage was suggested at 7 days, due to permissible spirotetramat concentration in terms of an acceptable MRL. The findings of the study will be used as the analytical reference point for developing spirotetramat safety guidelines for use in the vegetables investigated.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"5 1","pages":"964 - 976"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80355150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Neuro-2a cell-based assay for toxicity equivalency factor - proposal and evaluation in Chilean contaminated shellfish samples 以神经-2a细胞为基础的毒性等效因子测定-智利受污染贝类样品的建议和评价

Food Additives & Contaminants: Part A Pub Date : 2020-01-02 DOI: 10.1080/19440049.2019.1676919

Ambbar Aballay-González, J. Gallardo-Rodríguez, Macarena Silva-Higuera, Alejandra Rivera, V. Ulloa, Lorena Delgado-Rivera, Andrea Rivera-Belmar, Allisson Astuya

{"title":"Neuro-2a cell-based assay for toxicity equivalency factor - proposal and evaluation in Chilean contaminated shellfish samples","authors":"Ambbar Aballay-González, J. Gallardo-Rodríguez, Macarena Silva-Higuera, Alejandra Rivera, V. Ulloa, Lorena Delgado-Rivera, Andrea Rivera-Belmar, Allisson Astuya","doi":"10.1080/19440049.2019.1676919","DOIUrl":"https://doi.org/10.1080/19440049.2019.1676919","url":null,"abstract":"ABSTRACT There are two official PSP detection methods (mouse bioassay and HLPC-FLD) and a number of alternative methods. Ethical considerations have led to regulations being adopted in some countries that limit or prohibit the application of mouse bioassay. Analytical methodologies (e.g. HPLC-FLD or LC-MSMS) have the disadvantages of not being able to detect new toxins or analogues or reflecting the overall toxicity of the sample. In addition, they require highly trained personnel and expensive equipment, which are not always available. In this work, we have evaluated a method based on the Neuro-2a cell-based assay to detect substances that inhibit voltage-dependent sodium channels (Manger’s method). We tested PSP standards and natural samples contaminated with PSP. Here we demonstrate that the adapted Manger’s method is suitable for calculating Toxicity Equivalency Factors (TEF) for STX-analogues. The method was shown to be useful for screening contaminated natural samples in concentrations above the regulatory limit for these toxins (80 μg STX equivalents/100 g shellfish). We were able to detect PSP in 19 natural mollusc samples from South Chile despite the presence of other marine toxins. These preliminary results suggest that the method could be used as a first step in screening programmes.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"38 1","pages":"162 - 173"},"PeriodicalIF":0.0,"publicationDate":"2020-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81911783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Preparative isolation and purification of B-type fumonisins by using macroporous resin column and high-speed countercurrent chromatography 采用大孔树脂柱和高速逆流色谱分离纯化b型伏马菌素

Food Additives & Contaminants: Part A Pub Date : 2020-01-02 DOI: 10.1080/19440049.2019.1678768

Junqiang Hu, Hui Lv, Mingxuan Hou, Gang Wang, Yin-Won Lee, J. Shi, Z. Gu, Jianhong Xu

引用次数: 2

The impact of infant formula production on the concentrations of 3-MCPD and glycidyl esters 婴儿配方奶粉生产对3-MCPD和缩水甘油酯浓度的影响

Food Additives & Contaminants: Part A Pub Date : 2020-01-02 DOI: 10.1080/19440049.2019.1672898

Jessica K Beekman, S. Macmahon

{"title":"The impact of infant formula production on the concentrations of 3-MCPD and glycidyl esters","authors":"Jessica K Beekman, S. Macmahon","doi":"10.1080/19440049.2019.1672898","DOIUrl":"https://doi.org/10.1080/19440049.2019.1672898","url":null,"abstract":"ABSTRACT Fatty acid esters of 3-monochloropropanediol (3-MCPD), 2-monochlorpropanediol (2-MCPD), and glycidol are process-induced chemical contaminants found in refined vegetable oils. Due to their toxicological properties, there is potential concern regarding exposure to these compounds, particularly for formula-fed infants where refined edible oils are the primary fat source in commercial infant formulas. In order to assess exposure, 55 commercial oil samples, specifically intended for use in infant formula, were collected in 2015 from various infant formula manufacturers in the United States and analysed using a LC-MS/MS direct detection method. At the time of collection, there were no validated methods for the analysis of MCPD and glycidyl esters in infant formula. Therefore, analysis of these commercial oil samples served as an alternative for confirming the presence of these ester contaminants in infant formula. Bound 3-MCPD and glycidol concentrations in these oils ranged from below the limit of quantitation (<LOQ) to 5.13 µg g−1 and <LOQ to 6.14 µg g−1, respectively. Highest ester concentrations were observed in palm olein samples. Concentrations of bound 3-MCPD and glycidol in the commercial oils were consistent with previously published occurrence studies at the time, suggesting that oils used in the manufacture of infant formula were similar (or processed in a similar manner) as refined oils marketed directly to consumers in 2015. In order to determine if conditions during infant formula production impact the presence of 3-MCPD and glycidyl esters in the finished products, concentrations in oils were compared to concentrations in finished infant formula collected at approximately the same time. The comparison revealed that conditions used in the manufacture of infant formula likely initiate the destruction or conversion of glycidyl esters to other compounds, resulting in lower amounts of bound glycidol in the final product relative to the concentrations originally present in the refined oils. GRAPHICAL ABSTRACT","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"21 1","pages":"48 - 60"},"PeriodicalIF":0.0,"publicationDate":"2020-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83271987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13