Folia medica Cracoviensia最新文献_第8页

Does the incidence of infectious endocarditis show seasonal patterns? - a single center retrospective study. 感染性心内膜炎的发病率是否有季节性?-单中心回顾性研究。

Folia medica Cracoviensia Pub Date : 2023-04-30 DOI: 10.24425/fmc.2023.145428

Anna Tofilska, Katarzyna Zięba, Andrzej Surdacki, Marek Rajzer, Agnieszka Olszanecka

{"title":"Does the incidence of infectious endocarditis show seasonal patterns? - a single center retrospective study.","authors":"Anna Tofilska, Katarzyna Zięba, Andrzej Surdacki, Marek Rajzer, Agnieszka Olszanecka","doi":"10.24425/fmc.2023.145428","DOIUrl":"https://doi.org/10.24425/fmc.2023.145428","url":null,"abstract":"I n t r o d u c t i o n: Seasonal variation has been observed for bacterial and viral infections (e.g., COVID-19 [1]), but also for numerous cardiac problems. However, little information is available on the seasonality of infectious endocarditis (IE), a rare disease that is usually linked to a bacterial origin. Data from the Polish population are lacking. Materials and M e t h o d s: Our retrospective study focused on the identification of patients with IE, who were hospitalized at the University Hospital in Krakow between 2005-2022. For this purpose, we searched the medical records system using the ICD-10 code. We decided to divide our patients into four groups (winter, spring, summer, autumn), based on the date of admission to the hospital. Comparison of the distribution of IE incidents by season was performed with the ch2 test. R e s u l t s: One hundred and ten patients were included in the study (median age 62.5 years (range 20-94), 72 men (65.45%)). The left native valve IE was diagnosed in 49% of the patients, the prosthetic valve IE in 16%, the right valve IE in 27% and the implantable cardiac electronic devices IE in 12% of the subjects. The outcomes comprised of cardiac surgery (n = 53), embolism (n = 16), death (n = 15) and metastatic infections (n = 5). No differences in the incidence of IE by season were observed. C o n c l u s i o n s: In the preliminary observation of IE cases of patients admitted to the University Hospital in Krakow, Poland no seasonal pattern of IE was detected. Therefore, IE should be taken into account in the differential diagnosis at any time of the year.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"63 1","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9793326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical aspects of the treatment of atopic dermatitis with topical glucocorticoids and calcineurin inhibitors - a pilot questionnaire study. 局部糖皮质激素和钙调磷酸酶抑制剂治疗特应性皮炎的临床方面-一项试点问卷研究。

Folia medica Cracoviensia Pub Date : 2023-04-30 DOI: 10.24425/fmc.2023.145433

Przemysław Hałubiec, Andrzej Kazimierz Jaworek, Anna Wojas-Pelc

{"title":"Clinical aspects of the treatment of atopic dermatitis with topical glucocorticoids and calcineurin inhibitors - a pilot questionnaire study.","authors":"Przemysław Hałubiec, Andrzej Kazimierz Jaworek, Anna Wojas-Pelc","doi":"10.24425/fmc.2023.145433","DOIUrl":"https://doi.org/10.24425/fmc.2023.145433","url":null,"abstract":"Atopic dermatitis (AD) is the most common inflammatory skin disease. However, recent reports concerning the simple clinical aspects of treatment with topical glucocorticosteroids (TCS) and calcineurin inhibitors (TCI) are lacking. The objective of this study is providing an update on these characteristics of AD management. A group of 150 adults suffering from AD treated with TCS during last year was asked to fill an anonymous questionnaire. The course of topical treatment was analyzed in the context of the severity of symptoms and the knowledge of the patients about therapy. During the last year, the majority of patients (66%) were treated with class IV TCS; however, in the last two weeks, class I TCS was used the most frequently (35%). Only 11% were familiar with the concept of intermittent therapy and 4% used the fingertip unit (FTU). In total, 77% of them used TCI. Most of the patients used the same class of TCS permanently. Unfortunately, patients are unaware of simple approaches (like intermittent therapy or FTU) that increase both the effectiveness and safety of the treatment. Practicians should be aware of these problems to identify and eliminate them, primarily through the education of patients.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"63 1","pages":"97-108"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9802329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detecting undetectable - epidemiology, etiology, and diagnosis of carcinoma of unknown primary - systematic review. 发现无法检测的-原发不明的癌症的流行病学、病因学和诊断-系统回顾。

Folia medica Cracoviensia Pub Date : 2023-04-30 DOI: 10.24425/fmc.2023.145427

Justyna Ostojewska, Iga Wieczorek, Olaf Pachciński, Wojciech Zdziennicki, Franciszek Burdan

{"title":"Detecting undetectable - epidemiology, etiology, and diagnosis of carcinoma of unknown primary - systematic review.","authors":"Justyna Ostojewska, Iga Wieczorek, Olaf Pachciński, Wojciech Zdziennicki, Franciszek Burdan","doi":"10.24425/fmc.2023.145427","DOIUrl":"https://doi.org/10.24425/fmc.2023.145427","url":null,"abstract":"Carcinoma of unknown primary (CUP) is a heterogeneous group of oncological diseases in which it is impossible to determine the primary tumor. The incidence is 3-5% of oncologic patients, but the survival time varies from 6 weeks to 5 months. The diagnostics should begin with a clinical evaluation and basic laboratory tests. For CUP placed in head and neck the positron emission tomography - computed tomography is recommended; pancreatic or lung neoplasms are diagnosed with the computed tomography as well. Recently, the magnetic resonance, especially whole-body diffusion-weighted imaging has been introduced to the imaging panel. The lesion obtained during surgically removed metastases or biopsy material should be histopathological and molecularly examined to define the type of tumor. The basic immunoexpression panel should include cytokeratin-5/6, -7 and -20, EMA, synaptophysin, chromogranin, vimentin and GATA3 and molecular expression of ERBB2, PIK3CA, NF1, NF2, BRAF, IDH1, PTEN, FGFR2, EGFR, MET and CDK6. During the accurate diagnostics enable to classify malignancy of undefined primary origin as provisional CUP or finally confirmed CUP in which the primary place of tumor remains undetectable. The detailed diagnostics should be performed in highly specified centers to establish an accurate diagnosis and to initiate personalized treatment. Majority of patients are diagnosed with adenocarcinoma (70%), undifferentiated carcinoma (20%), squamous cell or transitional cell/uroepithelial carcinoma (5-10%), neuroendocrine tumor (5%) and with minor incidence other histological types, including melanoma.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"63 1","pages":"19-37"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9793325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Squamous Cell Carcinoma of perineal area developed from the Buschke-Löwenstein tumor. 会阴区鳞状细胞癌起源于Buschke-Löwenstein肿瘤。

Folia medica Cracoviensia Pub Date : 2023-04-30 DOI: 10.24425/fmc.2023.145432

Grzegorz J Stępień, Jakub Włodarczyk, Marcin Włodarczyk, Łukasz Dziki

引用次数: 0

Analysis of the epidemic situation of the COVID-19 coronavirus infection in Ukraine. 乌克兰新型冠状病毒感染疫情分析

Folia medica Cracoviensia Pub Date : 2023-04-30 DOI: 10.24425/fmc.2023.145434

Alla Podavalenko, Nina Malysh, Viktoriya Zadorozhna, Kateryna Zhuk, Galina Zaitseva, Inna Chorna

{"title":"Analysis of the epidemic situation of the COVID-19 coronavirus infection in Ukraine.","authors":"Alla Podavalenko, Nina Malysh, Viktoriya Zadorozhna, Kateryna Zhuk, Galina Zaitseva, Inna Chorna","doi":"10.24425/fmc.2023.145434","DOIUrl":"https://doi.org/10.24425/fmc.2023.145434","url":null,"abstract":"The epidemic process of COVID-19 in the world developed rapidly. The situation with morbidity, despite the establishment of quarantine, the introduction of restrictive anti-epidemic measures, and vaccination, remains difficult. The results of research on the influence of meteorological factors on the dynamics of the incidence of COVID-19, hospitalization, and mortality are ambiguous and contradictory. The purpose of this study is to analyze the indicators of morbidity, hospitalization, and mortality from COVID-19 in Ukraine, and to establish the level of influence of meteorological factors on them. A high variation in morbidity, hospitalization, and mortality rates was observed in Ukraine, in 2020-2021. A total of 3 waves of disease growth were established. The curve of hospitalization indicators of patients with COVID-19 had a correlation dependence on the incidence curve r = 0.766 (р <0.05), the maximum rates of hospitalization and mortality were registered in September-December 2021. A direct strong correlation was established between the frequency of registration of cases of COVID-19 and mortality - r = 0.899 (р <0.05). Most cases of COVID-19 were registered in the cold season, the least in June-August. Inverse correlations of moderate strength were established between the indicators of morbidity, hospitalization, and mortality and air temperature levels (-0.370< r <-0.461). Direct correlations of average strength (0.538< r <0.632) were established with the levels of relative air humidity.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"63 1","pages":"109-120"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10179348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Retrospective analysis of a case report of a left ovarian ectopic pregnancy after the former tubal 前输卵管后左卵巢异位妊娠1例回顾性分析

Folia medica Cracoviensia Pub Date : 2023-03-09 DOI: 10.24425/fmc.2022.142372

Anna Wrona, Veronika Aleksandrovych, Anna Gil, Magdalena Kurnik-Łucka, Jerzy A Walocha, Krzysztof Gil

引用次数: 0

Higher milk consumption is not associated with fracture risk reduction: systematic review and meta-analysis 高牛奶消费量与骨折风险降低无关:系统回顾和荟萃分析

Folia medica Cracoviensia Pub Date : 2023-03-09 DOI: 10.24425/fmc.2022.144088

Grzegorz Goncerz, Patrycja Kojm, Sylwia Skocelas, Krzysztof Więckowski, Tomasz Gallina, Paulina Pietrzyk, Sebastian Goncerz

引用次数: 0

Folia medica Cracoviensia Pub Date : 2023-03-09 DOI: 10.24425/fmc.2022.144079

Damian Ucieklak, Sandra Mrozińska, Aleksandra Wojnarska, Maciej T Małecki, Tomasz Klupa, Bartłomiej Matejko

{"title":"Habits related to the use of insulin infusion set in patients with type 1 diabetes on pump therapy — the effect of the educational intervention","authors":"Damian Ucieklak, Sandra Mrozińska, Aleksandra Wojnarska, Maciej T Małecki, Tomasz Klupa, Bartłomiej Matejko","doi":"10.24425/fmc.2022.144079","DOIUrl":"https://doi.org/10.24425/fmc.2022.144079","url":null,"abstract":"Proper use of insulin infusion sets (IIS) plays an important role in pump therapy of patients with type 1 diabetes mellitus (T1DM). We assessed the habits associated with the use of IIS in patients with T1DM treated with insulin pump.This study included 79 T1DM patients who were examined for the presence of lipohypertrophy (LH) and retrained for proper IIS use. They completed a standard questionnaire regarding IIS at the time of study entry and at the follow-up. R e s u l t s: At baseline, most of the patients declared to have been using a plastic cannula (n = 68; 86.1%), changing the infusion set regularly (n = 65; 82.3%), and placing the infusion sets on the abdomen wall (n = 68; 86.1%). The most common rotation habit was the \"curve pattern\" on both sides of the umbilicus (n = 16; 20.3%). After a median of 23 weeks (IQR 20-34), 58 patients were available for the follow-up. A rise in the proportion of patients who declared to change IIS regularly (n = 48; 82.8% vs. n = 57; 98.3%, p = 0.016), change IIS every 2 to 3 days (n = 27; 46.6% vs. n = 35; 60.3%, p = 0.043), use \"crisscross\" rotation (n = 5; 8.8% vs. n = 12; 21.4%, p = 0.027) was observed. There were less patients reporting not having repeatable rotation manner (n = 15; 26.3% vs. n = 2; 5.4%, p = 0.009). C o n c l u s i o n s: A substantial proportion of T1DM patients on pump therapy declare that they do not follow the recommended principles of IIS use. The intervention consisting of LH assessment and retrain- ing of proper use of IIS might be effective in improving patient compliance.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136170577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inguinal hernia management in preterm infants: addressing current issues of interest. 腹股沟疝管理的早产儿:解决当前的问题感兴趣。

Folia medica Cracoviensia Pub Date : 2023-03-09 DOI: 10.24425/fmc.2020.136203

I. Patoulias, I. Gkalonaki, D. Patoulias

引用次数: 1

Past strong experiences determine acute cardiovascular autonomic responses to acoustic stress. 过去的强烈经历决定了对声学应激的急性心血管自主反应。

Folia medica Cracoviensia Pub Date : 2023-02-21 DOI: 10.24425/fmc.2020.136206

Michał Jurczyk, Andrzej Boryczko, A. Furgała, Adrian Poniatowski, A. Surdacki, K. Gil

{"title":"Past strong experiences determine acute cardiovascular autonomic responses to acoustic stress.","authors":"Michał Jurczyk, Andrzej Boryczko, A. Furgała, Adrian Poniatowski, A. Surdacki, K. Gil","doi":"10.24425/fmc.2020.136206","DOIUrl":"https://doi.org/10.24425/fmc.2020.136206","url":null,"abstract":"BACKGROUND\u0000Stress is a major risk factor for cardiovascular (CV) disease. We hypothesized that past strong experiences might modulate acute CV autonomic responses to an unexpected acoustic stimulus. A i m: The study's aim was to compare acute CV autonomic responses to acoustic stress between students with and without a past strong experience associated with the acoustic stimulus.\u0000\u0000\u0000MATERIALS AND METHODS\u0000Twenty five healthy young volunteers - medical and non-medical students - were included in the study. CV hemodynamic parameters, heart rate (HR), and blood pressure (BP) variability were assessed for 10 min at rest and for 10 min after two different acoustic stimuli: a standard sound signal and a specific sound signal used during a practical anatomy exam (so-called \"pins\").\u0000\u0000\u0000RESULTS\u0000Both sounds stimulated the autonomic nervous system. The \"pins\" signal caused a stronger increase in HR in medical students (69 ± 10 vs. 73 ± 13 bpm, p = 0.004) when compared to non-medical students (69 ± 6 vs. 70 ± 10, p = 0.695). Rises in diastolic BP, observed 15 seconds after sound stressors, were more pronounced after the \"pins\" sound than after the standard sound signal only in medical students (3.1% and 1.4% vs. 3% and 4.4%), which was also reflected by low-frequency diastolic BP variability (medical students: 6.2 ± 1.6 vs. 4.1 ± 0.8 ms2, p = 0.04; non-medical students: 6.0 ± 4.3 vs. 4.1 ± 2.6 ms2, p = 0.06).\u0000\u0000\u0000CONCLUSIONS\u0000The \"pins\" sound, which medical students remembered from their anatomy practical exam, provoked greater sympathetic activity in the medical student group than in their non-medical peers. Thus, past strong experiences modulate CV autonomic responses to acute acoustic stress.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"60 4 1","pages":"79-95"},"PeriodicalIF":0.0,"publicationDate":"2023-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47459371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0