Folia medica Cracoviensia最新文献_第10页

Compound motor action potentials in transient and persistent phrenic nerve injury - metanalysis. 短暂性和持续性膈神经损伤的复合运动动作电位meta分析。

Folia medica Cracoviensia Pub Date : 2022-12-29 DOI: 10.24425/fmc.2022.144087

Marcin Kuniewicz, Marcin Kowalski, Grzegorz Karkowski, Nicholas Jacob, Rafał Badacz, Tomasz Rajs, Jacek Legutko

{"title":"Compound motor action potentials in transient and persistent phrenic nerve injury - metanalysis.","authors":"Marcin Kuniewicz, Marcin Kowalski, Grzegorz Karkowski, Nicholas Jacob, Rafał Badacz, Tomasz Rajs, Jacek Legutko","doi":"10.24425/fmc.2022.144087","DOIUrl":"https://doi.org/10.24425/fmc.2022.144087","url":null,"abstract":"Background: The right phrenic nerve is vulnerable to injury (PNI) during cryoballoon ablation (CBA) isolation of the right pulmonary veins. The complication can be transient or persistent. The reported incidence of PNI fluctuates from 4.73% to 24.7% depending on changes over time, CBA generation, and selected protective methods. M e t h o d s: Through September 2019, a database search was performed on MEDLINE, EMBASE, and Cochrane Database. In the selected articles, the references were also extensively searched. The study provides a comprehensive meta-analysis of the overall prevalence of PNI, assesses the transient to persistent PNI ratio, the outcome of using compound motor action potentials (CMAP), and estimated average time to nerve recovery. R e s u l t s: From 2008 to 2019, 10,341 records from 48 trials were included. Out of 783 PNI retrieved from the studies, 589 (5.7%) and 194 (1.9%) were persistent. CMAP caused a significant reduction in the risk of persistent PNI from 2.3% to 1.1% (p = 0.05; odds ratio [OR] 2.13) in all CBA groups. The mean time to PNI recovery extended beyond the hospital discharge was significantly shorter in CMAP group at three months on average versus non CMAP at six months (p = 0.012). CMAP (in contrast to non-CMAP procedures) detects PNI earlier from 4 to 16 sec (p <0.05; I2 = 74.53%) and 3 to 9o (p <0.05; I2 = 97.24%) earlier. C o n c l u s i o n s: Right PNI extending beyond hospitalization is a relatively rare complication. CMAP use causes a significant decrease in the risk of prolonged injury and shortens the time to recovery.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"62 4","pages":"99-120"},"PeriodicalIF":0.0,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10817814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total ankle arthroplasty with the use of Zimmer prosthesis and a review of the results of previous research conducted in this field. 使用Zimmer假体的全踝关节置换术以及对该领域先前研究结果的回顾。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142369

Artur Fałek, Szymon Skwarcz, Artur Staszczuk, Marek Paździor

引用次数: 0

The Inhibitory Effect of Human Plasma Albumin and Haptoglobin on Platelet Aggregation and 5-HT Release. 人血浆白蛋白和触珠蛋白对血小板聚集和5-HT释放的抑制作用。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142365

Nadia Khan, Magdalena Kurnik-Łucka, Gniewomir Latacz, Krzysztof Gil, Sheikh Arshad Saeed

{"title":"The Inhibitory Effect of Human Plasma Albumin and Haptoglobin on Platelet Aggregation and 5-HT Release.","authors":"Nadia Khan, Magdalena Kurnik-Łucka, Gniewomir Latacz, Krzysztof Gil, Sheikh Arshad Saeed","doi":"10.24425/fmc.2022.142365","DOIUrl":"https://doi.org/10.24425/fmc.2022.142365","url":null,"abstract":"Platelet aggregation contributes to the pathogenesis of cardiovascular diseases. After activation it leads to dense granule secretion and 5-HT release. The question arises; how platelet aggregation is endogenously controlled during blood circulation. In preliminary studies, we observed that human platelets aggregate more rapidly when suspended in buffer as compared to those suspended in plasma (PRP). These observations point to the presence of an endogenous substance that may inhibit arachidonic acid- induced platelet aggregation. An analysis of plasma Cohn fractions demonstrated that most of the plasma inhibitory activity was associated with albumin-rich and α-globulin rich protein fractions. The identity of plasma endogenous inhibitors of platelet aggregation (EIPA) was established by affinity chromatography on Cibacron Blue F3G-A for specific removal of albumin. The association of α-globulins to EIPA activity was recognized as due to haptoglobin by affinity chromatography on a column of hemoglobin-sepharose. In addition, we also found that the distribution of EIPA activity varies according to sex and physiological state. These findings reveal that EIPA may act by modulation of arachidonic acid metabolism or sequestering the fatty acid substrate.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"62 3","pages":"5-18"},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40655754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Modulating the activity of fluoropyrimidines against colorectal cancer by Vitamin D and its analogs. 维生素D及其类似物调节氟嘧啶抗结直肠癌的活性。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142368

Michał Jurczyk, Aleksandra Midro, Magdalena Król, Weronika Olesiak, Dariusz Stąpor, Anna Gil, Krzysztof Gil

{"title":"Modulating the activity of fluoropyrimidines against colorectal cancer by Vitamin D and its analogs.","authors":"Michał Jurczyk, Aleksandra Midro, Magdalena Król, Weronika Olesiak, Dariusz Stąpor, Anna Gil, Krzysztof Gil","doi":"10.24425/fmc.2022.142368","DOIUrl":"https://doi.org/10.24425/fmc.2022.142368","url":null,"abstract":"Colorectal cancer (CRC) is the third most common malignancy worldwide and the second most deadly cancer. Scientists have projected that by 2040, the prevalence will reach up to 3.2 million new cases annually due to population aging, disadvantageous diet transformations, and elevated exposure to risk factors. In the past decades, the five-year survival rate in colorectal cancer has significantly increased to 65% due to the development of an early endoscopic diagnosis and new chemotherapeutic approaches. Fluoropyrimidines, such as 5-fluorouracil or capecitabine, are commonly used to treat CRC. One of the most fundamental mechanisms of 5-FU is based on the inhibition of thymidylate synthase. This action is responsible for the therapeutic, but also toxic, effects of the drug. In this short review, we discuss the possible effects of vitamin D activity on colorectal cancer cells in relation to fluoropyrimidines. PubMed, Embase, and Web of Science databases were searched up to January 2022 for studies on vitamin D and 5-fluorouracil interaction mechanisms. Original studies, case reports, and review articles were included. Vitamin D or its analogs target multiple biochemical pathways and modulate numerous pathophysiological mechanisms in the course of colon cancer, including those related to the pharmacological sites of fluoropyrimidines. However, the available data concerning vitamin D-fluoropyrimidine pharmacological interactions are limited, especially regarding patients suffering from colon cancer and being treated with fluoropyrimidines.s.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"62 3","pages":"51-61"},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40655757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Anesthesia for gynecological cancer surgery. 妇科肿瘤手术麻醉。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142366

Paweł Krawczyk, Tomasz Lonc, Rafał Świstek, Paweł Tyszecki, Janusz Andres

引用次数: 2

Risk factors for the development of temporomandibular disorders related to the work environment - a literature review and own experience. 与工作环境相关的颞下颌疾病发展的危险因素——文献综述和自身经验。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142367

Małgorzata Pihut, Magdalena Orczykowska, Andrzej Gala

{"title":"Risk factors for the development of temporomandibular disorders related to the work environment - a literature review and own experience.","authors":"Małgorzata Pihut, Magdalena Orczykowska, Andrzej Gala","doi":"10.24425/fmc.2022.142367","DOIUrl":"https://doi.org/10.24425/fmc.2022.142367","url":null,"abstract":"This article characterizes the etiology of temporomandibular disorder with particular emphasis on emotional factors that have a major impact on the development of these dysfunctions and the most common their symptoms. They mainly affect people in the third and fourth decade of life and women predominate among this group of patients. The article analyzes the current literature (Pub Med Database, Scopus and EMBASE) in relation to the conditions in the work environment, which often constitute important causes of emotional tensions, constant state of mental tension and susceptibility to the effects of stressors, which have an impact on the state of functioning of the musculoskeletal system of the masticatory system. Despite the high frequency of temporomandibular disorders, unfortunately only a few studies describe the influence of harmful factors related to the work environment, and own experience (information from the patient's interview) and data from the literature indicate a significant share of these factors in the development of temporomandibular disorder. The relationships and anatomical connections affecting the influence of stressors on the functioning of masticatory muscles and temporomandibular joints are also discussed. In conclusion, it should be stated that the work environment and the emotional tensions generated in it constitute a serious sociological problem and increase the risk of developing and intensify the symptoms of TMD.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"62 3","pages":"43-49"},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40655756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Physiotherapeutic rehabilitation of adolescent patients with temporomandibular disorders. 青少年颞下颌障碍患者的物理治疗康复。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142370

Małgorzata Pihut, Elżbieta Zarzecka-Francica, Andrzej Gala

{"title":"Physiotherapeutic rehabilitation of adolescent patients with temporomandibular disorders.","authors":"Małgorzata Pihut, Elżbieta Zarzecka-Francica, Andrzej Gala","doi":"10.24425/fmc.2022.142370","DOIUrl":"https://doi.org/10.24425/fmc.2022.142370","url":null,"abstract":"TMD is a group of pathological changes including increased tension in the masticatory muscles, pain in the muscles and/or the temporomandibular joints, abnormal range of the mandibular movement or the presence of acoustic symptoms in the joints in the form of clicking or poping. The aim of the project was to compare the effectiveness of two methods of physiotherapeutic rehabilitation, used in adolescent patients with temporomandibular disorders.Material and methods: The material consisted of 68 patients, aged 14 to 17, of both sexes, generally healthy, who came to the Dental Prosthetics Department for treatment due to pain in the masticatory muscles. Dental examination and diagnostics revealed Ia in all cases in accordance with RDC/TMD protocol. Manual therapy was performed in group I (34 people) and kinesitherapy with massage was performed in group II (34 people). Patients were allocated randomly to both groups. Contraindications were considered for both methods.Results: Within the first study, mean values of pain intensity between group I and group II were not significantly different (6.12 and 6.24 respectively). Within the second study significantly lower VAS scores in both groups have been revealed (0.92 and 0.74 respectively). Results of the first and second study differed significantly in both groups. Similar results were obtained for the maximum abduction of the mandible.Conclusions: The results of the conducted studies indicate a beneficial effect of the assessed physiotherapeutic procedures in terms of functional rehabilitation of adolescent patients with temporomandibular disorders.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"62 3","pages":"79-90"},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40655759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of acute hyperglycemia on baroreflex sensitivity in healthy young adults. 急性高血糖对健康青年压力反射敏感性的影响。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142374

Navkiran Ranjan, Kiran Prakash, Anita S Malhotra

{"title":"Effect of acute hyperglycemia on baroreflex sensitivity in healthy young adults.","authors":"Navkiran Ranjan, Kiran Prakash, Anita S Malhotra","doi":"10.24425/fmc.2022.142374","DOIUrl":"https://doi.org/10.24425/fmc.2022.142374","url":null,"abstract":"Background: Autonomic dysfunction, impaired baroreflex sensitivity (BRS), and deranged circulatory homeostasis have been observed in chronic hyperglycemia and found to be associated with increased cardiovascular morbidity and mortality. However, the acute effects of hyperglycemia in healthy subjects have been rarely studied. The present study explores the effect of acute hyperglycemia on conventional and unconventional parameters of BRS in healthy young adults.Methods: For the estimation of BRS beat-to-beat blood pressure (BP) and electrocardiogram were recorded in forty-two young, healthy subjects during fasting and at 1hr of the oral glucose load. Analysis of BRS was carried out by sequence and spectral method. Number of UP-, DOWN- and ALL-sequences between ramps of BP and RR-interval were calculated as an unconventional measure of BRS along with the other conventional parameters.Results: We observed significant alteration of unconventional parameters of autonomic functions [the number of sequences of UP- (p = 0.0039) and ALL-sequences (p = 0.0233) of systolic BP and RR interval; and, UP- (p = 0.0380), DOWN- (p = 0.0417) and ALL-sequences (p = 0.0313) of mean BP and RR- interval] during acute hyperglycemia as compared to the fasting state. However, no significant changes were observed in any of the conventional parameters of BRS during acute hyperglycemia as compared to the fasting state.Conclusions: Present study concludes that the unconventional parameters of BRS - the number of sequences between the ramp of BP and RR-interval - change significantly during acute hyperglycemia. However, the conventional parameters do not show significant changes during acute hyperglycemia. We may hypothesize that the relatively constant BRS is maintained at the expense of increased oscillations in the ramp of BP and RR-interval.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"62 3","pages":"111-122"},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40670405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The challenging diagnosis of acute scrotum: remaining difficulties and further insights. 具有挑战性的诊断急性阴囊:剩下的困难和进一步的见解。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142371

Ioanna Gkalonaki, Ioannis Patoulias, Michail Anastasakis, Christina Panteli, Dimitrios Patoulias

引用次数: 1

Notes about telocytes and immunity. 关于远端细胞和免疫的注意事项。

Folia medica Cracoviensia Pub Date : 2022-09-15 DOI: 10.24425/fmc.2022.142373

Veronika Aleksandrovych, Anna Gil, Adrian Poniatowski

引用次数: 1