European Radiology最新文献

{"title":"Prospective randomized study on the effect of music on anxiety and pain related to CT-guided percutaneous interventions.","authors":"Florian Nima Fleckenstein, Kara Ann Hecker, Florian Schusta, Anna Pöhlmann, Timo Alexander Auer, Bernhard Gebauer, Federico Collettini","doi":"10.1007/s00330-025-11441-3","DOIUrl":"https://doi.org/10.1007/s00330-025-11441-3","url":null,"abstract":"<p><strong>Background: </strong>CT-guided percutaneous interventions may cause patients to experience high levels of stress and anxiety, negatively affecting post-interventional outcomes. Music played during medical interventions has been shown to reduce anxiety and pain, yet the effect of music on patients undergoing interventional radiology procedures has not been evaluated. The aim of this study was to assess whether music played during CT-guided percutaneous interventions may reduce anxiety and pain.</p><p><strong>Methods: </strong>This prospective randomized controlled trial included patients undergoing CT-guided transcutaneous procedures. The final analysis included a total of 209 patients, randomized into a music group (MG, n = 107) and a control group (CG, n = 102). Items of state and trait anxiety were analysed using the short form of the State Trait Anxiety Inventory (STAI-6) before and after the procedure. Post-procedural pain was assessed with the numeric rating scale (NRS) with faces.</p><p><strong>Results: </strong>Patients in the MG exhibited lower anxiety and a greater reduction in anxiety levels as compared to patients in the CG (p < 0.001, respectively). The median change of anxiety was 6.5 ± 3.8 (range: -3 to 14) in the MG versus 3.7 ± 3.5 (range: -6 to 13) in the CG. Post-procedural pain showed a value of 2 ± 2.1 (median, range: 0 to 9) in the MG, versus 6 ± 2.4, (median, range: 0 to 10) in the CG.</p><p><strong>Conclusion: </strong>Exposure to music during CT-guided percutaneous interventions can aid in significantly lowering peri-interventional anxiety and pain and thus improve overall patient care without any negative side effects.</p><p><strong>Key points: </strong>Question Does listening to music during CT-guided percutaneous interventions reduce peri-interventional anxiety and pain in patients? Findings This prospective randomized-controlled trial found that patients exposed to music during CT-guided interventions experienced significantly lower levels of anxiety and pain compared to those in a control group. Clinical relevance Incorporating music into CT-guided interventions provides an easy, non-invasive, and cost-effective method to reduce patient anxiety and pain in the clinical setting.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translational approaches for radiation protection: treating patients, not their images.","authors":"Moreno Zanardo, Luca Maria Sconfienza","doi":"10.1007/s00330-025-11458-8","DOIUrl":"https://doi.org/10.1007/s00330-025-11458-8","url":null,"abstract":"","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annual percentage change of MR Parkinsonism index in progressive supranuclear palsy: a feasibility study.","authors":"Min Wang, Jiaying Lu, Ling Li, Fengtao Liu, Fangyang Jiao, Ping Wu, Jingjie Ge, Luyao Wang, Matthias Brendel, Axel Rominger, Kuangyu Shi, Jian Wang, Chuantao Zuo, Jiehui Jiang","doi":"10.1007/s00330-025-11440-4","DOIUrl":"https://doi.org/10.1007/s00330-025-11440-4","url":null,"abstract":"<p><strong>Objectives: </strong>Considerable evidence suggests that midbrain-based magnetic resonance Parkinsonism index (MRPI) measurements are reliable biomarkers for the diagnosis of progressive supranuclear palsy (PSP). However, the longitudinal atrophy pattern of PSP and potential differences in change rates among PSP phenotypic spectrum remain unclear. This study aims to investigate the longitudinal changes of MRPI measurements and explore their potential role in PSP phenotype progression monitoring.</p><p><strong>Materials and methods: </strong>Thirty-six patients with PSP-Richardson's syndrome (PSP-RS), 21 patients with variant PSP (vPSP), and 21 healthy controls (HCs) with longitudinal MRI and clinical follow-up were enrolled. Midbrain-based morphometric measurements and the corresponding annual percentage changes (APCs) were measured and further used to evaluate the associations with disease progression.</p><p><strong>Results: </strong>Significant differences in midbrain-based morphometric biomarkers were observed both at baseline and longitudinal trajectories between PSP and HC groups, but no significant differences were found between PSP-RS and vPSP subgroups. Baseline comprehensive measurements were significantly associated with the baseline PSP rating scale (PSPrs) in all PSP and PSP phenotypes. The APC of MRPI was significantly associated with the APC of PSPrs in all PSP (r = 0.267, p = 0.046) and the PSP-RS subgroup (r = 0.386, p = 0.020).</p><p><strong>Conclusions: </strong>This study characterizes the longitudinal atrophy trajectory of PSP phenotypes and the significant associations between morphometric measurements and disease severity. Dissecting the causal associations among core 4R-tau, dopamine, and subsequent atrophy trajectories may enhance the application of these biomarkers for phenotype attribution.</p><p><strong>Key points: </strong>Questions The use of midbrain-based MRPI measurements to assess the longitudinal prognosis of the PSP phenotype remains uncertain. Findings Significant differences in midbrain-based morphometric biomarkers were observed both at baseline and longitudinal trajectories between PSP and health control groups. Clinical relevance Midbrain-based morphometric measurements hold promise as potential radiological biomarkers for monitoring PSP disease progression and assessment.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebellar hemorrhages in very preterm infants: presence, involvement of the dentate nucleus, and cerebellar hypoplasia are associated with adverse cognitive outcomes.","authors":"Karla Drommelschmidt, Thomas Mayrhofer, Borek Foldyna, Hanna Müller, Janika Raudzus, Sophia L Göricke, Bernd Schweiger, Selma Sirin","doi":"10.1007/s00330-025-11452-0","DOIUrl":"https://doi.org/10.1007/s00330-025-11452-0","url":null,"abstract":"<p><strong>Objective: </strong>Impaired cognition is a frequent complication of prematurity, closely related to patients' outcomes. Imaging features of cerebellar hemorrhages (CBH) related to impaired cognition are not well studied. This study evaluated the relationship between cMRI-derived CBH characteristics and clinical risk factors for adverse cognition.</p><p><strong>Methods: </strong>Our analysis is threefold: (1) We included very preterm infants (2009-2018) undergoing cMRI, and compared clinical and cMRI findings between infants with and without CBH. (2) In the CBH cohort, we associated clinical and imaging findings with cognitive outcomes (Bayley Score of Infant Development at two years corrected age, impaired outcomes: < 85) using uni- and multivariable logistic regression analyses. (3) We conducted a matched pair case-control analysis (CBH vs. no CBH) matching for gestational age (GA) and supratentorial injury.</p><p><strong>Results: </strong>Among the 507 infants (52% male; mean GA 26.8 ± 2.7 weeks), 53 (10.5%) presented with CBH. Cognition was impaired in those with CBH (case-control: 88 (IQR: 75-110) vs. 105 (IQR: 90-112), p < 0.001), even in those with CBH < 5 mm (case-control: 95 (IQR: 77.5-115) vs. 105 (IQR: 91-113), p = 0.037). In infants with CBH, red-blood-cell-transfusion requirement (odds ratio (OR) 1.32, 95% CI: 1.01-1.72, p = 0.037), dentate nucleus involvement (OR 17.61, 95% CI: 1.83-169.83, p = 0.013) and moderate-to-severe cerebellar hypoplasia (OR 26.41, 95% CI: 1.11-626.21, p = 0.043) were independent predictors of impaired cognition. Adding dentate nucleus involvement to cerebellar hypoplasia increased the discriminatory capacity (AUC 0.85 vs. 0.71, p = 0.004).</p><p><strong>Conclusion: </strong>CBH (even < 5 mm) impact cognitive outcomes of very preterm infants, underlining the cerebellum's importance for cognition. In infants with CBH, involvement of the dentate nucleus and moderate-to-severe cerebellar hypoplasia are independent structural risk factors for impaired cognition.</p><p><strong>Key points: </strong>Question The cerebellum is important for cognition. Cerebellar hemorrhages are common in preterm infants, but the imaging features related to impaired cognition are not well studied. Findings Even small cerebellar hemorrhages affected cognition. Involvement of the dentate nucleus and moderate-to-severe cerebellar hypoplasia were identified as new structural risk factors for adverse cognition. Clinical relevance Cerebral MRI enables precise diagnosis of cerebellar hemorrhages and the detection of structural risk factors for adverse cognition like dentate nucleus involvement and cerebellar moderate-to-severe hypoplasia. This knowledge facilitates risk estimation, structured follow-up, and interventions after prematurity.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular penetration sign: dual-phase enhanced CT manifestations of atypical liver abscess caused by Klebsiella pneumoniae.","authors":"Tao Yuan, TangLi Zhong, Jun Song","doi":"10.1007/s00330-025-11460-0","DOIUrl":"https://doi.org/10.1007/s00330-025-11460-0","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to investigate the multislice spiral computed tomography (MSCT) features of atypical liver abscesses caused by Klebsiella pneumoniae (KP).</p><p><strong>Methods: </strong>A retrospective review was conducted on patients with atypical KP-caused liver abscesses, as verified by biopsy or surgery, from October 2019 to December 2023. All patients underwent dual-phase enhanced CT scan, and MSCT findings were analysed.</p><p><strong>Results: </strong>Seventy-two patients (58.5 ± 12.3 years, 43 males, 29 females) with atypical KP-induced liver abscess and 115 lesions were identified. Vascular penetration was detected in twelve lesions, presenting as vascular thickening, indistinct margins, and irregular invasive alterations. Among them, three lesions were initially misdiagnosed as primary hepatic lymphoma (PHL). Additionally, 50 lesions exhibited imaging patterns such as the \"honeycomb\", \"petal\", or \"cluster\" signs, and 40 lesions showed \"lesion shrinkage\" sign. Transient abnormal enhancement in hepatic parenchyma was observed in 83 lesions.</p><p><strong>Conclusion: </strong>Vascular penetration with inflammatory infiltration might be a crucial sign in the diagnosis of atypical liver abscess caused by KP; correctly recognising this sign could reduce misdiagnosis.</p><p><strong>Key points: </strong>Question Early imaging diagnosis of atypical liver abscesses caused by Klebsiella pneumoniae is significant because microbiology or blood cultures are time-consuming and may delay appropriate treatment. Findings The vascular penetration sign was noted in some Klebsiella pneumoniae atypical liver abscesses and play a vital role in the diagnosis of this disease. Clinical relevance The newly discovered vascular penetration sign in this study is an important sign for identifying atypical liver abscesses caused by Klebsiella pneumoniae. Accurate identification of this sign facilitates early clinical diagnosis and diminishes the risk of misdiagnosis.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracranial atherosclerotic plaque features on vessel wall imaging predict first ever and recurrence of stroke: a meta-analysis.","authors":"Jinhuan Zhang, Beibei Sun, Huayu Wang, Hanrui Shi, Qiuting Wen, Mahmud Mossa-Basha, Chengcheng Zhu","doi":"10.1007/s00330-025-11451-1","DOIUrl":"https://doi.org/10.1007/s00330-025-11451-1","url":null,"abstract":"<p><strong>Objectives: </strong>Intracranial atherosclerotic disease (ICAD) features on vessel wall magnetic resonance imaging (VW-MRI) are associated with first-ever or recurrent ischemic stroke (IS) or transient ischemic attack (TIA). There are multiple longitudinal ICAD VW-MRI studies, but they are limited by small sample size, non-standardized imaging acquisition and analysis, and some controversial results. Hence, we conducted the current meta-analysis of intracranial plaque features predicting recurrence of IS.</p><p><strong>Materials and methods: </strong>PubMed, Web of Science, and EMBASE databases were searched through March 2024. Two independent reviewers extracted data on study design, VW-MRI techniques, and patient outcome. Quality assessment was used by the NOS tool. Subgroup analyses, sensitivity analysis, and evaluation of publication bias were also performed.</p><p><strong>Results: </strong>For recurrent IS, eighteen studies were included for meta-analysis, comprising 2240 participants, and 472 participants had recurrent IS during an average of 16-month follow-up. All studies were of high quality with an NOS score ≥ 7. Plaque enhancement (OR 2.18, [95% CI 1.70-4.65]), plaque enhancement ratio (SMD 0.46, [95% CI 0.15-0.77]), plaque thickness, (SMD 0.271, [95% CI 0.047-0.496]), T1-weighted (T1W) hyperintensity, (OR 2.58, [95% CI 1.56-4.26]), and degree of stenosis (SMD 0.41, [95% CI 0.03-0.79]) significantly predicted IS recurrence. Subgroup analyses found plaque enhancement was significantly higher in the IS and TIA recurrence group as compared to the non-recurrence group (OR 3.39, 95% CI 1.84-6.22).</p><p><strong>Conclusion: </strong>Plaque enhancement, plaque enhancement ratio, plaque thickness, T1W hyperintensity and degree of stenosis emerged as strong imaging biomarkers of recurrence of stroke.</p><p><strong>Clinical trial registration: </strong>Clinical trial registration no: CRD42023479678.</p><p><strong>Key points: </strong>Questions Several studies suggest that vessel wall MRI (VWMRI) features of intracranial atherosclerotic disease (ICAD) may be associated with first-time or recurrent ischemic strokes, though this remains a debated topic. Findings Our study demonstrates that plaque enhancement, plaque enhancement ratio, plaque thickness, T1W hyperintensity, and degree of stenosis are strong imaging biomarkers for predicting stroke recurrence. Clinical relevance Incorporating these features into post-stroke evaluations using VWMRI could help guide patient management more effectively, enabling more targeted treatments for secondary stroke prevention.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Node-RADS category on preoperative CT predicts prognosis in patients with papillary renal cell carcinoma.","authors":"Xiaoxia Li, Dengqiang Lin, Ying Xiong, Weifeng Lin, Shaoting Zhang, Shunfa Huang, Jianjun Zhou, Chenchen Dai","doi":"10.1007/s00330-025-11446-y","DOIUrl":"https://doi.org/10.1007/s00330-025-11446-y","url":null,"abstract":"<p><strong>Objectives: </strong>This research focused on investigating the relationship between the Node Reporting and Data System (Node-RADS) categories, determined via preoperative CT, and the outcomes of progression-free survival (PFS) and cancer-specific survival (CSS) in individuals diagnosed with papillary renal cell carcinoma (pRCC).</p><p><strong>Methods: </strong>A retrospective multicenter study initially enrolled 454 patients, with 218 eligible for analysis following partial nephrectomy or radical resection for pRCC. Prognostic factors related to PFS and CSS in pRCC patients were identified through univariate and multivariate Cox regression analyses. Subsequently, the prognostic value of Node-RADS was assessed and compared with the existing pRCC risk stratification model.</p><p><strong>Results: </strong>In total, 218 patients (mean age, 58 years; men, 164 [75.2%]) with pRCC (186 Node-rads I tumors (85.3%), 10 Node-rads II tumors (4.6%), and 22 Node-rads III tumors (10.1%)) were included. The Node-RADS category emerged as an independent prognostic factor for PFS (III vs II vs I, hazard ratio (HR) 4.250, p < 0.001) and CSS (III vs II vs I, HR 4.466; p < 0.001). When the Node-RADS category was incorporated into Leibovich's model, the resulting combined model demonstrated a significant improvement in predictive accuracy (C-index: 0.865 versus 0.755, p = 0.005 for PFS; and 0.921 versus 0.835, p = 0.01 for CSS).</p><p><strong>Conclusion: </strong>The Node-RADS category has been identified as a more accurate predictor of prognosis for pRCC, regardless of pathologic lymph node involvement. These findings need further confirmation in prospective studies.</p><p><strong>Key points: </strong>Question Lymph node status is important for papillary renal cell carcinoma prognosis, and there is a lack of consensus on radiological evaluation. Findings Node-RADS is an independent predictor of progression-free survival and cancer-specific survival in papillary renal cell carcinoma. Clinical relevance The Node Reporting and Data System category improves the accuracy of the Leibovich model for prognosis, which can help clinical practitioners select individualized treatment plans for each patient.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large language models for error detection in radiology reports: a comparative analysis between closed-source and privacy-compliant open-source models.","authors":"Babak Salam, Claire Stüwe, Sebastian Nowak, Alois M Sprinkart, Maike Theis, Dmitrij Kravchenko, Narine Mesropyan, Tatjana Dell, Christoph Endler, Claus C Pieper, Daniel L Kuetting, Julian A Luetkens, Alexander Isaak","doi":"10.1007/s00330-025-11438-y","DOIUrl":"https://doi.org/10.1007/s00330-025-11438-y","url":null,"abstract":"<p><strong>Purpose: </strong>Large language models (LLMs) like Generative Pre-trained Transformer 4 (GPT-4) can assist in detecting errors in radiology reports, but privacy concerns limit their clinical applicability. This study compares closed-source and privacy-compliant open-source LLMs for detecting common errors in radiology reports.</p><p><strong>Materials and methods: </strong>A total of 120 radiology reports were compiled (30 each from X-ray, ultrasound, CT, and MRI). Subsequently, 397 errors from five categories (typographical, numerical, findings-impression discrepancies, omission/insertion, interpretation) were inserted into 100 of these reports; 20 reports were left unchanged. Two open-source models (Llama 3-70b, Mixtral 8x22b) and two commercial closed-source (GPT-4, GPT-4o) were tasked with error detection using identical prompts. The Kruskall-Wallis test and paired t-test were used for statistical analysis.</p><p><strong>Results: </strong>Open-source LLMs required less processing time per radiology report than closed-source LLMs (6 ± 2 s vs. 13 ± 4 s; p < 0.001). Closed-source LLMs achieved higher error detection rates than open-source LLMs (GPT-4o: 88% [348/397; 95% CI: 86, 92], GPT-4: 83% [328/397; 95% CI: 80, 87], Llama 3-70b: 79% [311/397; 95% CI: 76, 83], Mixtral 8x22b: 73% [288/397; 95% CI: 68, 77]; p < 0.001). Numerical errors (88% [67/76; 95% CI: 82, 93]) were detected significantly more often than typographical errors (75% [65/86; 95% CI: 68, 82]; p = 0.02), discrepancies between findings and impression (73% [73/101; 95% CI: 67, 80]; p < 0.01), and interpretation errors (70% [50/71; 95% CI: 62, 78]; p = 0.001).</p><p><strong>Conclusion: </strong>Open-source LLMs demonstrated effective error detection, albeit with comparatively lower accuracy than commercial closed-source models, and have potential for clinical applications when deployed via privacy-compliant local hosting solutions.</p><p><strong>Key points: </strong>Question Can privacy-compliant open-source large language models (LLMs) match the error-detection performance of commercial non-privacy-compliant closed-source models in radiology reports? Findings Closed-source LLMs achieved slightly higher accuracy in detecting radiology report errors than open-source models, with Llama 3-70b yielding the best results among the open-source models. Clinical relevance Open-source LLMs offer a privacy-compliant alternative for automated error detection in radiology reports, improving clinical workflow efficiency while ensuring patient data confidentiality. Further refinement could enhance their accuracy, contributing to better diagnosis and patient care.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reproducibility of methodological radiomics score (METRICS): an intra- and inter-rater reliability study endorsed by EuSoMII.","authors":"Tugba Akinci D'Antonoli, Armando Ugo Cavallo, Burak Kocak, Alessandra Borgheresi, Andrea Ponsiglione, Arnaldo Stanzione, Emmanouil Koltsakis, Fabio Martino Doniselli, Federica Vernuccio, Lorenzo Ugga, Matthaios Triantafyllou, Merel Huisman, Michail E Klontzas, Romina Trotta, Roberto Cannella, Salvatore Claudio Fanni, Renato Cuocolo","doi":"10.1007/s00330-025-11443-1","DOIUrl":"https://doi.org/10.1007/s00330-025-11443-1","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the intra- and inter-rater reliability of the total methodological radiomics score (METRICS) and its items through a multi-reader analysis.</p><p><strong>Materials and methods: </strong>A total of 12 raters with different backgrounds and experience levels were recruited for the study. Based on their level of expertise, raters were randomly assigned to the following groups: two inter-rater reliability groups, and two intra-rater reliability groups, where each group included one group with and one group without a preliminary training session on the use of METRICS. Inter-rater reliability groups assessed all 34 papers, while intra-rater reliability groups completed the assessment of 17 papers twice within 21 days each time, and a \"wash out\" period of 60 days in between.</p><p><strong>Results: </strong>Inter-rater reliability was poor to moderate between raters of group 1 (without training; ICC = 0.393; 95% CI = 0.115-0.630; p = 0.002), and between raters of group 2 (with training; ICC = 0.433; 95% CI = 0.127-0.671; p = 0.002). The intra-rater analysis was excellent for raters 9 and 12, good to excellent for raters 8 and 10, moderate to excellent for rater 7, and poor to good for rater 11.</p><p><strong>Conclusion: </strong>The intra-rater reliability of the METRICS score was relatively good, while the inter-rater reliability was relatively low. This highlights the need for further efforts to achieve a common understanding of METRICS items, as well as resources consisting of explanations, elaborations, and examples to improve reproducibility and enhance their usability and robustness.</p><p><strong>Key points: </strong>Questions Guidelines and scoring tools are necessary to improve the quality of radiomics research; however, the application of these tools is challenging for less experienced raters. Findings Intra-rater reliability was high across all raters regardless of experience level or previous training, and inter-rater reliability was generally poor to moderate across raters. Clinical relevance Guidelines and scoring tools are necessary for proper reporting in radiomics research and for closing the gap between research and clinical implementation. There is a need for further resources offering explanations, elaborations, and examples to enhance the usability and robustness of these guidelines.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The scientific evidence of commercial AI products for MRI acceleration: a systematic review.","authors":"Stefan J Fransen, Christian Roest, Frank F J Simonis, Derya Yakar, Thomas C Kwee","doi":"10.1007/s00330-025-11423-5","DOIUrl":"https://doi.org/10.1007/s00330-025-11423-5","url":null,"abstract":"<p><strong>Objectives: </strong>This study explores the methods employed by commercially available AI products to accelerate MRI protocols and investigates the strength of their diagnostic image quality assessment.</p><p><strong>Materials and methods: </strong>All commercial AI products for MRI acceleration were identified from the exhibitors presented at the RSNA 2023 and ECR 2024 annual meetings. Peer-reviewed scientific articles describing validation of clinical performance were searched for each product. Information was extracted regarding the MRI acceleration technique, achieved acceleration, diagnostic performance metrics, test cohort, and hallucinatory artifacts. The strength of the diagnostic image quality was assessed using scientific evidence levels ranging from \"product's technical feasibility for clinical purposes\" to \"product's economic impact on society\".</p><p><strong>Results: </strong>Out of 1046 companies, 14 products of 14 companies were included. No scientific articles were found for four products (29%). For the remaining ten products (71%), 21 articles were retrieved. Four acceleration methods were identified: noise reduction, raw data reconstruction, personalized scanning protocols, and synthetic image generation. Only a limited number of articles prospectively demonstrated impact on patient outcomes (n = 4, 19%), and no articles discussed an evaluation in a prospective cohort of > 100 patients or performed an economic analysis. None of the articles performed an analysis of hallucinatory artifacts.</p><p><strong>Conclusion: </strong>Currently, commercially available AI products for MRI acceleration can be categorized into four main methods. The acceleration methods lack prospective scientific evidence on clinical performance in large cohorts and economic analysis, which would help to get a better insight into their diagnostic performance and enable safe and effective clinical implementation.</p><p><strong>Key points: </strong>Question There is a growing interest in AI products that reduce MRI scan time, but an overview of these methods and their scientific evidence is missing. Findings Only a limited number of articles (n = 4, 19%) prospectively demonstrated the impact of the software for accelerating MRI on diagnostic performance metrics. Clinical relevance Although various commercially available products shorten MRI acquisition time, more studies in large cohorts are needed to get a better insight into the diagnostic performance of AI-constructed MRI.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}