Reduction of radiation exposure and preserved image quality using photon-counting detector cardiac computed tomography without electrocardiographic gating in children with congenital heart disease.

Abstract

Objectives: To evaluate the radiation exposure, quantitative, and qualitative image quality in pediatric cardiac CT by using photon-counting detector computed tomography (PCD CT) versus energy-integrating detector CT (EID CT) in matched children.

Materials and methods: Thirty-seven contrast-enhanced, clinically indicated cardiac CTs performed on PCD CT were matched with 37 examinations acquired by EID CT. The patients were matched according to water-equivalent diameters. Quantitative evaluation of image quality comprised a region of interest (ROI)-based analysis, calculating image noise, signal-to-noise (SNR) and contrast-to-noise (CNR) ratio. Differences of the attenuation variation of the paraspinal and the pectoral muscles were calculated to measure beam hardening artifacts. Volume CT dose index (CTDI_vol) and dose length product (DLP) were documented, and the effective radiation dose was calculated for each patient. Statistical analysis comprised t-tests and Wilcoxon signed rank tests.

Results: The mean age of the children on PCD CT was 794 ± 1016 days, similar to the mean age of 815 ± 957 days of the children on EID CT (p = 0.76). Moreover, age, height, weight, and body mass index (BMI) were also not significantly different between the two groups (p ≥ 0.32). Radiation exposure was significantly lower on PCD CT (CTDI_vol 0.20 ± 0.12 mGy and DLP 4.06 ± 3.22 mGy*cm) versus EID CT (CTDI_vol 0.37 ± 0.17 mGy, p < 0.001 and DLP 7.21 ± 4.67 mGy*cm, p < 0.001). No significant differences in SNR, CNR, or beam hardening artifacts could be observed. Qualitative image quality was also comparable for PCD CT versus EID CT.

Conclusions: With a reduction in radiation exposure exceeding 40% by using PCD CT, image quality remained stable compared to EID CT. Reducing radiation with PCD CT while preserving image quality might substantially advance cardiac imaging in children.

Key points: Question Children are particularly sensitive to radiation exposure, highlighting the need for dose reduction. Findings Radiation dosage can be significantly reduced while preserving image quality when using photon-counting detector (PCD) CT in pediatric patients with congenital heart disease. Clinical relevance Since radiation exposure can be significantly reduced by PCD CT compared to energy-integrating detector (EID) CT, while image quality was comparable, PCD CT is advisable for children with congenital heart disease.