European Journal of Dentistry最新文献

{"title":"Osteogenesis Potential of Polymethylmethacrylate-Hydroxyapatite and Stem Cells from Human Exfoliated Deciduous Teeth as Alveolar Bone Graft: An In Silico Study.","authors":"Tania Saskianti, Michelle Angelina, Ardianti Maartina Dewi, Yulanda Antonius, Amelinda Nabila Zahri, Rini Devijanti Ridwan, Masami Kanawa, Takeshi Kawamoto, Kotaro Tanimoto, Katsumi Fujimoto","doi":"10.1055/s-0044-1801280","DOIUrl":"https://doi.org/10.1055/s-0044-1801280","url":null,"abstract":"<p><strong>Objective: </strong> The goal is to analyze the osteogenesis potential of polymethylmethacrylate (PMMA)-hydroxyapatite (HA) and stem cells from human exfoliated deciduous teeth (SHED) as a biomaterial candidate for alveolar bone defect therapy through a bioinformatic approach within an <i>in silico</i> study.</p><p><strong>Materials and methods: </strong> Three-dimensional (3D) ligand structures consisting of HA, PMMA, and target proteins of SHED were obtained from the PubChem database. STITCH was used for SHED target protein analysis, STRING was utilized for analysis and visualization of protein pathways related to osteogenesis, PASS Online was employed to predict biological functions supporting osteogenesis potential, PyRx 0.8 was used for molecular docking analysis, and PyMol was utilized to visualize the 3D structures resulting from the molecular docking analysis.</p><p><strong>Results: </strong> PMMA ligand was found to support osteogenesis through several biological functions, while interaction of HA ligand with matrix metalloproteinase (MMP) 20, DSPP, IBSP, SPP1, CD44, and MMP7 protein was revealed to play a role specifically in extracellular matrix organization. The interaction of all these proteins played a role in various pathways of osteogenesis. Toxicity level predictions of PMMA and HA were at class V and class III, respectively, which means that both ligands were shown to be neither hepatotoxic, carcinogenic, immunotoxic, nor cytotoxic. However, the ligand of PMMA had a lower binding affinity to SHED's protein (MMP7, MMP20, CD44, BMP7, and COL1A1) than the control ligand.</p><p><strong>Conclusion: </strong> The interaction between HA-PMMA ligands and several SHED proteins showed biological process and osteogenesis pathways supporting the osteogenesis potential of PMMA-HA and SHED for alveolar bone defect therapy.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Regeneration Potential of Bone Marrow-Derived Mesenchymal Stem Cells on Induced Damaged Submandibular Salivary Gland in Mice.","authors":"Nadia Attia Radi, Doaa Adel Habba, Seham Ibrahim Hallool, Ahmed Ali Almeshari, Hanaa Mohamed Abd Elsamia","doi":"10.1055/s-0044-1791940","DOIUrl":"https://doi.org/10.1055/s-0044-1791940","url":null,"abstract":"<p><strong>Objectives: </strong> The ultimate goal of stem cell (SC) transplantation is the regeneration of salivary gland function by transplanted SCs differentiating into salivary gland cells. Therefore, this study aimed to evaluate the regenerative capacity of bone marrow-derived mesenchymal stem cells (BM-MSCs) transplantation in irradiated mice using the immunohistochemical markers Ki-67 and CD34.</p><p><strong>Material and methods: </strong> Four groups of male mice were included in the study. Group I (normal control) comprised six mice that were not subjected to gamma radiation. Group II comprised six irradiated mice that were not treated with BM-MSCs. Group III comprised 12 irradiated mice that were treated with intraglandular injection of labeled BM-MSCs into their submandibular salivary glands, 24 hours postradiation. Group IV comprised 12 irradiated mice that were treated with intraglandular injection of labeled BM-MSCs into their submandibular salivary glands, on day 11 postradiation.</p><p><strong>Statistical analysis: </strong> Data were presented as mean and standard deviation. The different groups were compared using a one-way analysis of variance (ANOVA).</p><p><strong>Results: </strong> The ANOVA test revealed that the difference between all groups was extremely statistically significant (<i>p</i> < 0.003), and Tukey's post hoc test revealed a statistically significant difference between group II and groups I, III, and IV included in the study regarding microvessel density of CD34 immunoexpression in different groups.</p><p><strong>Conclusion: </strong> BM-MSCs have a regeneration potential on induced damaged submandibular salivary glands in mice; time is an essential factor in the regeneration capacity of BM-MSCs.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing the Surface Quality of L-PBF Ti6Al4V ELI Alloy via Electropolishing and Its Effect on Corrosion Resistance for Dental Applications.","authors":"Venus Chatpaiboonwat, Vorapat Trachoo, Patcharapit Promoppatum, Viriyah Chobaomsup, Kanokwan Saengkiettiyut, Viritpon Srimaneepong, Kamolporn Wattanasirmkit","doi":"10.1055/s-0045-1802572","DOIUrl":"https://doi.org/10.1055/s-0045-1802572","url":null,"abstract":"<p><strong>Objectives: </strong> The Ti6Al4V ELI alloy produced via laser powder bed fusion (L-PBF) has attracted interest for use in dental applications. However, surface finishing is an important property that can be managed by various methods. The purpose of this study was to investigate the effects of electropolishing (EP) on the surface roughness and corrosion resistance of L-PBF Ti6Al4V ELI alloy.</p><p><strong>Materials and methods: </strong> The present study explored the influence of current density (0.3 A/cm²), voltage (15 V), and distance (2 and 4 cm) on the surface quality of L-PBF-printed Ti6Al4V ELI. The potentiodynamic polarization testing was performed to investigate the corrosion behavior of electropolished Ti6Al4V ELI alloy plates.</p><p><strong>Statistical analysis: </strong> The data variation was compared at different conditions of EP using a one-way analysis of variance and Tukey's <i>post hoc</i> testing at a significance level of 5%.</p><p><strong>Results: </strong> This study showed that EP significantly reduced the surface roughness and enhanced corrosion resistance of printed Ti6Al4V ELI alloy with the best result achieved by using 15 V and 2 cm of anode-cathode distance.</p><p><strong>Conclusion: </strong> This study indicates that customized EP settings are crucial for optimizing the surface properties of Ti6Al4V ELI for use in dental and biomedical applications. However, the corrosion resistance can be reduced due to increased porosity resulting from the EP treatment.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Repair Materials and Surface Treatments on the Shear Bond Strength of 3D-Printed Provisional Restoration.","authors":"Pattaramon Hanpongkittikun, Wissanee Jia-Mahasap, Boonchai Chaoklaiwong","doi":"10.1055/s-0044-1791979","DOIUrl":"https://doi.org/10.1055/s-0044-1791979","url":null,"abstract":"<p><strong>Objective: </strong> Despite the emergence of numerous three-dimensional (3D) printed provisional resin, there are no conclusive guidelines for repairing them. This study aims to investigate the effects of different repair materials and surface treatments on the shear bond strength of 3D-printed provisional resin.</p><p><strong>Materials and methods: </strong> A total of 180 3D-printed resin specimens underwent six surface treatments: no surface treatment (control), silicon carbide paper (SP), sandblasting with aluminum oxide (SB), SP followed by SB (SP + SB), SP with bonding agent (SP + BD), and SB with bonding agent (SB + BD). Each group was repaired with polymethyl methacrylate (PMMA), Bis-acryl, and flowable composite resin (FCR). The shear bond strength of the bonded specimens was tested using a universal testing machine and the mode of failure was examined with stereomicroscope.</p><p><strong>Statistical analysis: </strong> The Shapiro-Wilk test was used to assess normal distribution, and two-way analysis of variance (ANOVA; <i>α</i> = 0.05) was used to find the effect of independent variables on the shear bond strength. The post hoc test was achieved using the Tukey honest significant difference (HSD) test.</p><p><strong>Results: </strong> Two-way ANOVA indicated a statistically significant interaction between repair materials and surface treatments in relation to the shear bond strength of 3D-printed resin (<i>p</i> < 0.001). The three highest shear bond strengths overall were SB repaired with Bis-acryl (17.30 ± 0.77 MPa), SB + BD repaired with FCR (17.20 ± 0.29 MPa), and SB + BD repaired with PMMA (16.60 ± 0.71 MPa), which were significantly higher than their control group (<i>p</i> < 0.001). However, there were no significant differences between these groups. Notably the lowest shear bond strength in PMMA occurred in the control group (8.49 ± 0.42 MPa), while the lowest shear bond strength in Bis-acryl and FCR was observed in the SP group (7.28 ± 0.71 and 8.84 ± 1.15 MPa, respectively).</p><p><strong>Conclusion: </strong> Repair materials and surface treatments play an important role in repairing 3D-printed resin. PMMA and composite resin-based repair materials require both sandblast and a chemical bonding agent, while Bis-acryl-based repair materials only need sandblasting to improve the shear bond strength.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Static Computer-Assisted Implant Placement in Narrow Ridge by Novice Clinicians.","authors":"Jaafar Abduo, Radhwan Himmadi Hasan, Douglas Lau","doi":"10.1055/s-0045-1802949","DOIUrl":"https://doi.org/10.1055/s-0045-1802949","url":null,"abstract":"<p><strong>Objective: </strong> This study aimed to evaluate the accuracy and clinical impact of implant placement by novice implant clinicians in the narrow anterior ridge by fully guided (FG), pilot-guided (PG), and freehand (FH) placements.</p><p><strong>Materials and methods: </strong> A maxillary surgical model with missing incisors and a narrow ridge was designed. Two implants were planned in the lateral incisor locations to receive screw-retained implant prosthesis. Fifteen novice implant clinicians placed implants according to every placement. Angle, vertical and horizontal platform, and horizontal apex deviations from the planned implant were measured. The clinical impact evaluation aimed to relate the position of each placed implant to (1) periimplant bone dimension after implant placement and (2) the prosthesis retention mechanism.</p><p><strong>Results: </strong> The FG implants were more accurate than PG implants at the angle (<i>p</i> = 0.001) and maximum horizontal apex deviations (<i>p</i> = 0.001), and were more accurate than FH implants for all comparisons (<i>p</i> = 0.001). The PG implants were superior to FH implants at the maximal horizontal platform deviation (<i>p</i> = 0.001). All FG implants were fully covered with bone and could be restored with screw-retained prostheses. One PG implant (3.3%) had fenestration at the apex, and one PG implant (3.3%) could not be restored with screw-retained prosthesis. Seven FH implants (23.3%) had fenestration at the apex, and one FH implant (3.3%) suffered from dehiscence. Seven FH implants (23.3%) were not restorable with screw-retained prosthesis.</p><p><strong>Conclusion: </strong> For novice clinicians, a significantly greater accuracy was observed for FG placement, followed by PG and FH placements. FH implants experienced significant compromise of periimplant bone dimension and the prosthesis retention mechanism.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of CAD-CAM Workflow Variations on the Marginal and Internal Gaps and Fatigue Behavior of Ceramic and Resin Composite Dental Crowns.","authors":"Rafaela Oliveira Pilecco, Lucas Saldanha da Rosa, Andrea Baldi, Renan Vaz Machry, João Paulo Mendes Tribst, Luiz Felipe Valandro, Cornelis Johannes Kleverlaan, Nicola Scotti, Gabriel Kalil Rocha Pereira","doi":"10.1055/s-0044-1791705","DOIUrl":"https://doi.org/10.1055/s-0044-1791705","url":null,"abstract":"<p><strong>Objectives: </strong> To analyze the marginal/internal gap and the fatigue behavior of crowns made of two different materials, using four combinations of a digital workflow-two intraoral scanners (IOSs) and two milling machines.</p><p><strong>Materials and methods: </strong> Crowns were made considering three factors: IOS (a confocal microscopy-based scanner: TRIOS 3-TR; or a combination of active triangulation and dynamic confocal microscopy: Primescan-PS), milling machines (four-axis: CEREC MC XL-CR or five-axis: PrograMill PM7-PM), and restorative material (lithium disilicate-LD or resin composite-RC) (<i>n</i> = 10). The bonding surface of each crown was treated and bonded to each respective glass fiber-reinforced epoxy resin die using a dual-cure resin cement. A computed microtomography analysis was performed to access marginal/internal gap. The specimens were subjected to a cyclic fatigue test (20 Hz, initial load = 100 N/5,000 cycles; step size= 50 N/10,000 cycles until 1,500 N, then if specimens survived, the step size was increased to 100 N/10,000 cycles).</p><p><strong>Statistical analysis: </strong> For data analysis, three-way analysis of variance and Kaplan-Meier with log-rank (Mantel-Cox) test were performed (α = 0.05).</p><p><strong>Results: </strong> TR resulted in a smaller axial-occlusal angle and occlusal gap, and five-axis milling resulted in a smaller marginal gap, axial-occlusal angle, and occlusal gap. Angled points and occlusal surface showed a tendency for overmilling. RC crowns displayed higher survival rates and a more pronounced topography compared with LD independently of the scanning and milling method. LD crowns produced with a five-axis milling machine resulted in higher fatigue performance and rougher topography compared with a four-axis machine.</p><p><strong>Conclusion: </strong> RC crowns displayed better fatigue behavior compared with LD, while LD benefited from a five-axis machine for improved survival probability.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Vertical Marginal Discrepancy in High and Low Translucent Monolithic Zirconia Crowns in Repeated Firing Cycles.","authors":"Mehrzad Moazzam, Amirhossein Fathi, Mahsa Ghorbani, Ramin Mosharraf","doi":"10.1055/s-0044-1801303","DOIUrl":"https://doi.org/10.1055/s-0044-1801303","url":null,"abstract":"<p><strong>Objective: </strong> Increase in vertical marginal discrepancy (VMD) during repeated firing cycles and its clinical outcomes is a major concern for high and low translucent monolithic zirconia crowns. The purpose of this in vitro study was to evaluate and compare VMD in high and low translucent monolithic zirconia crowns in repeated firing cycles.</p><p><strong>Material and methods: </strong> To perform this study, 10 monolithic zirconia crowns made by computer-aided design and computer-aided manufacturing method were used in two groups of five with high and low translucency, which were designed on Zimmer tissue-level implant abutment. The crowns in each group were randomly numbered from 1 to 5 and each underwent 1, 3, and 5 firing cycles. After completing each mentioned cycle, the VMD was measured at eight predetermined points on abutment by optical microscope and their average was recorded for each sample. Data analysis was done by SPSS 22 software through repeated-measure analysis of variance, paired <i>t</i>-test, and <i>t</i>-test with a 5% significance threshold.</p><p><strong>Results: </strong> A total of 240 measurements were made for the VMD, which, due to the presence of five samples in each translucency group and eight examined points in each sample, was finally summed up to six averages for each translucency group in the mentioned three stages of firing cycles. The averages for the low-translucency group after 1, 3, and 5 firing cycles were 76.86, 85.02, and 90.55 μm, respectively, and for the high-translucency group after 1, 3, and 5 firing cycles were 80.38, 87.33, and 97.78 μm, respectively. The average VMD of the samples regardless of the translucency level after 1, 3 and 5 firing cycles was calculated as 78.62, 86.18, and 94.16 μm, respectively.</p><p><strong>Conclusion: </strong> This study found that VMD increased with repeated firing cycles, with no significant difference between high- and low-translucency zirconia crowns. Repeated firings significantly raised VMD, but all values remained within clinically acceptable limits, supporting the suitability of both translucency types for clinical use.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Intermittent Fasting on Salivary Inflammatory Cytokines and Dopamine Levels.","authors":"Elyazia Fayyad, Zumurd Al Anoud, Abdulkader Habra, Hussein Al Meshal, Aghila Rani K G, Roba Saqan, Zuha Rizvi, Manal Awad, Natheer Al-Rawi","doi":"10.1055/s-0045-1802345","DOIUrl":"https://doi.org/10.1055/s-0045-1802345","url":null,"abstract":"<p><strong>Objectives: </strong> The current study elucidates potential alterations in inflammatory cytokines and dopamine (DA) levels in saliva following a 21-day fasting regimen during Ramadan and explores their associations with mental health parameters.</p><p><strong>Materials and methods: </strong> Forty-four healthy young university students (22 females and 22 males; median age 22 (2) and body mass index 23.40 (6.23) were enrolled, and saliva samples were collected before and after fasting. Cytokine and DA levels were quantified by ELISA and LEGENDplex Human Inflammation Panel, respectively. Participants also completed the Patient Health Questionnaire-9 and Depression Anxiety Stress Scales questionnaires to assess mental health.</p><p><strong>Statistical analysis: </strong> Data analysis was performed using SPSS. Differences between pre- and postfasting were tested using Wilcoxon's signed-rank test. Mann-Whitney's <i>U</i> test determined disparities in DA and cytokine levels across sex. Simple and multiple linear regression analyses were performed to identify the factors influencing the change in DA. Correlation analysis was employed to explore the relationships between the changes in DA and cytokine levels before and after fasting.</p><p><strong>Results: </strong> A significant increase in inflammatory cytokines such as interleukin (IL)-1β, interferon-α2, tumor necrosis factor-α, IL-23, IL-33, and IL-8 was observed after fasting. Anti-inflammatory cytokine, IL-10, levels remained unchanged. Females had significantly higher levels of proinflammatory cytokines before fasting compared with males, but no significant gender differences were observed after fasting. The current study also showed a significant decrease in DA levels after fasting; however, no significant difference in DA levels across genders was noted. Self-reported mental health status did not significantly change before and after fasting. Multiple linear regression analyses did not suggest potential associations between these variables and changes in DA levels before and after fasting. However, correlation analysis indicated that the change in inflammatory cytokine levels was inversely related to changes in DA levels.</p><p><strong>Conclusion: </strong> Fasting during Ramadan significantly increased salivary cytokine levels and decreased DA levels, indicating potential relationships between immune factors and mental well-being. The findings highlight the complex interplay between inflammation, immunity, and DA regulation during fasting. Further research is warranted to elucidate the potential long-term effects of these associations and their implications for mental health and well-being.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mandibular versus Maxillary Desmoplastic Fibroma: A Pooled Analysis of World Literature and Report of a New Case.","authors":"Taiseer Hussain Hassan Al-Khateeb","doi":"10.1055/s-0044-1801277","DOIUrl":"https://doi.org/10.1055/s-0044-1801277","url":null,"abstract":"<p><p>The purpose of this study is to delineate differences between mandibular and maxillary desmoplastic fibroma (DF) via analysis of published cases. Details of cases were analyzed for distribution, demographics, presentation, treatment, and follow-up. Between 1961 and 2022, 195 cases were reported, averaged 2.7 annually. There were 159 (81.5%) mandibular and 36 (18.5%) maxillary cases. The posterior mandible was most commonly affected (91.2%; <i>p</i> < 0.05). Maxillary DF mostly involved the anterior region (53.1%; <i>p</i> < 0.05). The female:male ratio was 1:1.3 (1:2 mandibular and 1:4 maxillary), and the average age was 13.5 years (12.1 mandibular and 20.5 maxillary) with a peak frequency in both jaws in the first decade of life (<i>p</i> < 0.05). Mandibular cases mostly affected whites, and maxillary cases affected a higher percentage of Asians (<i>p</i> < 0.05). Maxillary cases caused more pain and intraoral ulceration (<i>p</i> < 0.05). The combined cure rate of all treatment modalities for mandibular and maxillary cases was 74.8 and 81.5%, respectively. The most effective single-modality treatment for DF of both jaws was surgery (<i>p</i> < 0.05). To the best of our knowledge, this review is the first to delineate difference between mandibular and maxillary DF. This work will aid attaining an improved management protocol of this uncommon disease.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Dry Mouth and Factors Associated with Sarcopenia on Oral Health-Related Quality of Life in Peritoneal Dialysis Patients.","authors":"Natcha Boonyapratheeprat, Kununya Pimolbutr, Dulyapong Rungraungrayabkul, Sasiwimon Meenetkum, Sarinya Boongird, Piyatida Chuengsaman, Nis Okuma, Supanee Thanakun, Chagriya Kitiyakara, Sujiwan Seubbuk Sangkhamanee","doi":"10.1055/s-0045-1802567","DOIUrl":"https://doi.org/10.1055/s-0045-1802567","url":null,"abstract":"<p><strong>Objectives: </strong> This cross-sectional study aimed to investigate the oral health-related quality of life (OHRQoL), its associated factors, and the prevalence of possible sarcopenia in Thai well-maintained patients with end-stage renal disease (ESRD) undergoing peritoneal dialysis (PD).</p><p><strong>Materials and methods: </strong> Data were collected from 63 participants undergoing PD at Banphaeo-Charoenkrung Hemodialysis Center. Dry mouth was evaluated through unstimulated salivary flow rate measurement and self-reported xerostomia questionnaires. OHRQoL was assessed using the Thai version of Oral Health Impact Profile (OHIP-14).</p><p><strong>Statistical analysis: </strong> Statistical analyses were conducted using IBM SPSS Statistics version 21.0. Descriptive statistics summarized participant characteristics, and normality was tested with the Kolmogorov-Smirnov test. Continuous variables were expressed as medians and interquartile ranges, while categorical variables were presented as frequencies and percentages. The Mann-Whitney <i>U</i> test and Fisher's exact test were used to assess differences between OHRQoL groups. Partial Spearman's rank correlation examined variable relationships, and logistic regression identified factors linked to a higher negative impact on OHRQoL, adjusting for age, sex, body mass index, chair stand test, and salivary flow rate. A <i>p</i>-value of < 0.05 was considered significant.</p><p><strong>Results: </strong> The median age was 59 years (range 27-79), with a possible sarcopenia prevalence of 52.4%. OHIP-14 scores ranged from 0 to 32, with medians of 4 and 13 in a lower (<i>n</i> = 31) and higher (<i>n</i> = 32) negative impact on OHRQoL, respectively. Those with a higher negative impact on OHRQoL exhibited a significantly higher proportion of self-reported xerostomia (<i>p</i> = 0.01), lower salivary flow rate (<i>p</i> = 0.01), and longer 5-time chair stand test (<i>p</i> = 0.04) compared to individuals with the lower negative impact on OHRQoL. Correlation between the time of the chair stand test and the handgrip strength adjusting for age (<i>r</i> = -0.439, <i>p</i> < 0.001) and sex (<i>r</i> = -0.351, <i>p</i> = 0.006) was revealed. Multivariate logistic regression showed a significant association between salivary flow rate and a higher negative impact on OHRQoL (odds ratio 0.018; 95% confidence interval: 0.001, 0.545; <i>p</i> = 0.02).</p><p><strong>Conclusion: </strong> This finding suggests that reduced salivary flow affected OHRQoL in well-maintained ESRD patients with PD, highlighting the importance of managing dry mouth to alleviate their OHRQoL.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}