European journal of general medicine最新文献_第9页

Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Fibromyalgia 纤维肌痛患者中性粒细胞/淋巴细胞比值及血小板/淋巴细胞比值

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1525

Erdem Ilgün, Ö. Akyürek, A. Kalkan, Fethi Demir, M. Demirayak, M. Bilgi

{"title":"Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Fibromyalgia","authors":"Erdem Ilgün, Ö. Akyürek, A. Kalkan, Fethi Demir, M. Demirayak, M. Bilgi","doi":"10.15197/EJGM.1525","DOIUrl":"https://doi.org/10.15197/EJGM.1525","url":null,"abstract":"Objective:We aimed at contributing to the understanding of the pathophysiology of Fibromyalgia (FM) by measuring neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR), which are the systemic inflammatory response (SIR) markers in patients with fibromyalgia.Method:The study population consisted of 70 patients newly diagnosed with FM (mean (SD) age: 43.9 (±9.8) years, 80% were female) and 52 healthy volunteers (mean (SD) age: 43.4 (±10.4) years, 76.9% were female). American College of Rheumatology-ACR 1990 criteria regarding the evaluation of widespread pain and tender points were used for the diagnosis of FM. Demographic characteristics, anthropometrics and laboratory findings were used to make comparisons between patient and control groups.Results:PLR was 128.0 (±40.2) in the patient group while it was 110.5 (±33.6) in the control group and the difference was found to be significant (p=0.03). NLR was similar in both groups. The tender point count was significantly higher in the patient group (p<0.001) whereas there was a negative correlation between the tender point count and the lymphocyte count (r= -0.200; p=0.020) and a strong positive correlation with PLR (r=0.022; p=0.001).Conclusion:Our findings indicate that NLR levels were similar in both groups while the PLR values of the FM patients were found to be significantly higher than those of the control group and there was a positive correlation between PLR and the tender point count.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87500220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Surgical Complications of Simple and Complex Gastroschisis in Newborn 新生儿单纯性和复杂性胃裂的手术并发症

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1495

S. Méndez-Martínez, M. García-Carrasco, C. Mendoza-Pinto, E. García-Cano, Á. Montiel-Jarquín

引用次数: 6

In the Absence of Co-Morbidities Mean Platelet Volume is not A Severity Indicator in OSAS 在没有合并症的情况下，平均血小板体积不是OSAS的严重程度指标

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1555

Özgür Bilgin Topçuoğlu, G. Afşar, Sema Sarac, O. Oruc, Tülin Kuyucu

{"title":"In the Absence of Co-Morbidities Mean Platelet Volume is not A Severity Indicator in OSAS","authors":"Özgür Bilgin Topçuoğlu, G. Afşar, Sema Sarac, O. Oruc, Tülin Kuyucu","doi":"10.15197/EJGM.1555","DOIUrl":"https://doi.org/10.15197/EJGM.1555","url":null,"abstract":"Objective: To evaluate the relationship of mean platelet volume and OSAS severity, in OSAS patients without any vascular risk factors and co-morbidites. Method: The patients files and polysomnographies of OSAS patients who admitted to sleep laboratory between January 1st 2011 and April 1st 2012 have been retrospectively evaluated. Inclusion criteria are to have no vascular risk factors and no co-morbidities, to be a non-smoker, to be older than 18 years of age and not be taking any medications. Patients have been grouped as severe and non-severe OSAS according to their apne- hypopne indices. Mean platelet volume (MPV) of patients in the two groups have been compared. Results: Among 81 patients who met the inclusion criteria, 39.6% of the patients had severe OSAS while 60.4% had non-severe OSAS. MPV in the severe group was 9.05+0.89 (fL), while it was 9.00+0.82 (fL) in the non-severe group. The difference of MPV between two groups was not significant (p:0.800). Conclusion: Controversially with the former studies which declared higher MPV in severe OSAS, our study concludes that when all other risk factors are excluded MPV is not an indicator of severity in OSAS.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82018453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Challenges in Managing Severe Lower Limb Spasticity Associated with Bilateral Hip Joints Subluxation 处理双侧髋关节半脱位相关的严重下肢痉挛的挑战

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1475

O. Htwe, R. I. Hussain, A. S. Naicker

引用次数: 2

Recurrent Hypoglycaemia: an Uncommon Presentation in Sheehan Syndrome. 复发性低血糖:希恩综合征中一种罕见的表现。

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1457

H. Aggarwal, D. Jain, S. Pawar, A. Mittal, P. Jain

引用次数: 0

The Role of Surgical Diagnosis in The Choice of Anesthetic Technique 手术诊断在麻醉技术选择中的作用

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1458

Nureddin Yüzkat, L. Soyoral, M. B. Çeğin, B. Özkan, U. Goktas

引用次数: 2

Effect of Urtica Dioica against Doxorubicin-InducedCardiotoxicity in Rats through Suppression ofHistological Damage, Oxidative Stress and LipidPeroxidation 荨麻通过抑制组织损伤、氧化应激和脂质过氧化作用对抗阿霉素诱导的大鼠心脏毒性

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1567

M. Erboğa, Yeliz Bozdemir Donmez, U. Sener, Z. Erboğa, C. Aktas, M. Kanter

{"title":"Effect of Urtica Dioica against Doxorubicin-InducedCardiotoxicity in Rats through Suppression ofHistological Damage, Oxidative Stress and LipidPeroxidation","authors":"M. Erboğa, Yeliz Bozdemir Donmez, U. Sener, Z. Erboğa, C. Aktas, M. Kanter","doi":"10.15197/EJGM.1567","DOIUrl":"https://doi.org/10.15197/EJGM.1567","url":null,"abstract":"Objective: Doxorubicin (DOX) is a highly effective anti-cancer drug with limited clinical use due to its serious cardiotoxicity. Urtica dioica L. seeds (UD), have been widely used in folk medicine, particularly in the therapy for advanced cancer patients, possesses a potent anti-oxidant properties. The goal of present study was to investigate the cardioprotective effects of UD on DOX-induced cardiotoxicity. Method: The rats in the UD treated group were given intraperitoneally 2 ml/kg UD. To induce cardiotoxicity, 30 mg/kg DOX was injected intraperitoneally by a single dose and the rats were sacrificed after 48 h. Results: The present study revealed for the first time a protective role of UD against DOXinduced cardiotoxicity. UD therapy significantly protected against DOXinduced myocardial damage which was characterized by conduction abnormalities, vacuolization, inflammatory cell infiltration, hemorrhag es, and myofibrillar disarrangement. As indicators of oxidative stress, DOX caused significantly increase lipid peroxidation and reduction in activities of antioxidant enzymes; superoxide dismutase, glutathione peroxidase, and catalase. UD treatment significantly attenuated DOXinduced oxidative injury. Conclusion: The present study showed that UD might be a suitable cardioprotector against toxic effects of DOX.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76691230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Multiple Ileo-ileal Intussusceptions in a 3-Year-Old Child 1例3岁儿童多发回肠-回肠肠套叠

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1454

B. Kızılyıldız, B. Beger, B. Sönmez, K. Karaman

引用次数: 2

Tracheobronchial Foreign Bodies Aspirations in Adults: A 25-Years Experience 成人气管支气管异物插管:25年的经验

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1506

B. Altuntas, Y. Aydın, A. Eroğlu

{"title":"Tracheobronchial Foreign Bodies Aspirations in Adults: A 25-Years Experience","authors":"B. Altuntas, Y. Aydın, A. Eroğlu","doi":"10.15197/EJGM.1506","DOIUrl":"https://doi.org/10.15197/EJGM.1506","url":null,"abstract":"Objective:The incidence of tracheobronchial aspirations of foreign bodies in adults is lower than in children. In this article, we aimed to present our experience in tracheobronchial aspiration of foreign bodies in adults during 25-years.Methods:From January 1990 to January 2015, 122 patients older than 16 years with suspected tracheobronchial aspiration of foreign body were included in this study. Patients’ data cards were retrospectively assessed according to age, gender, clinical symptoms and physical examination findings, localization and type of foreign body, radiologic findings and therapeutic options.Results:Ninety-six of the patients were female (78.7%) and 26 were male (21.3%). The age range was 17-70 years and mean age was 30.3 years. Rigid bronchoscopy was performed in all patients. Foreign bodies were seen in 112 patients (91.8%). Foreign bodies were extracted by rigid bronchoscopy in 109 patients. Thoracotomy and pneumotomy were performed in the remaining 3 patients. The most common foreign body was pin (83%). The chief symptom was cough (100%). The most common anatomic location of foreign bodies was right bronchial system (60.7%). The main radiologic finding was radiopaque image of the related foreign body (88.4%). Right lower lobectomy was performed in two patients because of bronchiectasis.Conclusion:If tracheobronchial aspirations of foreign bodies are not treated in early period, irreversible and suppurative lung diseases may occur as results of aspirations in later years. The education of societies about this subject is principal precaution in reducing the frequency of tracheobronchial aspirations of foreign bodies.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80206113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Linezolid-induced Lactic Acidosis 利奈唑胺致乳酸性酸中毒

European journal of general medicine Pub Date : 2016-04-06 DOI: 10.15197/EJGM.1439

H. Rehman

引用次数: 37