Europace最新文献

{"title":"Correction to: Transforming atrial fibrillation management by targeting comorbidities and reducing atrial fibrillation burden: the 10th AFNET/EHRA consensus conference.","authors":"","doi":"10.1093/europace/euag280","DOIUrl":"https://doi.org/10.1093/europace/euag280","url":null,"abstract":"","PeriodicalId":11981,"journal":{"name":"Europace","volume":"28 10","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13629746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Electrical reconnection after pulsed field ablation with a circular over-the-wire catheter in atrial fibrillation.","authors":"","doi":"10.1093/europace/euag281","DOIUrl":"https://doi.org/10.1093/europace/euag281","url":null,"abstract":"","PeriodicalId":11981,"journal":{"name":"Europace","volume":"28 10","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13637613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term incidence of infective endocarditis according to the type of cardiac implantable electronic device: a nationwide comparison with moderate- and high-risk patient groups.","authors":"Amna Alhakak, Lauge Østergaard, Mohammed Bakir Ahmad Lafta, Michael Vinther, Berit Thornvig Philbert, Henning Bundgaard, Lars Køber, Emil Loldrup Fosbøl","doi":"10.1093/europace/euag232","DOIUrl":"10.1093/europace/euag232","url":null,"abstract":"<p><strong>Aims: </strong>According to the European Society of Cardiology (ESC) guidelines, patients with a cardiac implantable electronic device (CIED) are considered at moderate risk of infective endocarditis (IE), irrespective of CIED type. However, comparative data across CIED types and IE risk groups are limited. We examined IE rates according to CIED type compared with moderate- and high-risk groups.</p><p><strong>Methods and results: </strong>Danish nationwide registries were used to identify patients with first-time CIED implantation and reference populations at moderate and high risk of IE (2000-2022), based on the ESC guidelines. The high-risk group included patients with a left-sided prosthetic valve. Patients with prior IE or left-sided prosthetic valve were excluded from the CIED group. The primary outcome was incident IE within 10 years. The study included 84 171 CIED recipients, 127 966 moderate-risk patients, and 23 505 high-risk patients. Pacemakers were the most common CIED type (74.9%), followed by implantable cardioverter-defibrillator (16.6%), cardiac resynchronization therapy device with defibrillator (CRT-D) (4.6%), and cardiac resynchronization therapy device without defibrillator (3.9%). Pacemaker recipients were the oldest (median 78.2 years) and most frail. The 10-year cumulative incidence of IE was lowest in pacemaker recipients (1.0% [95% confidence interval (CI): 0.9-1.1]) and highest in CRT-D recipients (2.2% [95% CI: 1.7-2.9]). In adjusted analyses, all CIED types were associated with higher IE rates than the moderate-risk group but lower than the high-risk group.</p><p><strong>Conclusion: </strong>In this nationwide cohort, IE risk differed across CIED types, highest in CRT-D and lowest in pacemaker recipients. All CIED types were associated with higher risk than moderate-risk patients but lower risk than high-risk patients, supporting the ESC classification. Cardiac resynchronization therapy device with defibrillator recipients may warrant further evaluation of preventive strategies.</p>","PeriodicalId":11981,"journal":{"name":"Europace","volume":" ","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thirty years of percutaneous epicardial access: reflections on the evolution of ventricular tachycardia substrate mapping and ablation.","authors":"Mauricio Scanavacca","doi":"10.1093/europace/euag263","DOIUrl":"https://doi.org/10.1093/europace/euag263","url":null,"abstract":"","PeriodicalId":11981,"journal":{"name":"Europace","volume":"28 10","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive conduction system disease preceding hypertrophy in IVS4+919G>A Fabry variant: a population-based electrocardiographic study.","authors":"Wei-Hsin Chung, Cheng-Chang Tung, Ting-Yuan Liu, Wan-Jung Chang, Kuan-Cheng Chang, Wei-De Lin, Hsin-Yueh Liang, Fuu-Jen Tsai","doi":"10.1093/europace/euag258","DOIUrl":"10.1093/europace/euag258","url":null,"abstract":"<p><strong>Aims: </strong>The IVS4+919G>A variant is the most prevalent late-onset Fabry variant in East Asian populations, but its electrophysiological trajectory remains incompletely defined.</p><p><strong>Methods and results: </strong>From a regional genetic screening programme, 905 IVS4+919G>A carriers were identified among 457 581 patients and matched 1:2 to controls by age and sex. Electrocardiographic (ECG) parameters were compared across decades, and echocardiography correlated structural changes with ECG findings. The cumulative prevalence of IVS4+919G>A was 0.198%. Age-specific prevalence in females was ∼2.5-fold higher than in males (0.11-0.15%), without significant change throughout different age categories. Female carriers demonstrated the catch-up phenomenon after the age of 60. Males exhibited a nine-fold risk of right bundle branch block and pacemaker implantation compared with male controls (right bundle branch block, HR 9.286, 95% CI 5.16-16.70, P < 0.001; pacemaker implantation, HR 9.197, 95% CI 2.88-29.31, P < 0.001), and this precedes the onset of echocardiographic left ventricular hypertrophy. Risk of stroke and atrial fibrillation (HR 1.435, 95% CI 0.69-2.96, P = 0.289) was similar between male carriers and controls. PR interval did not shorten but was prolonged instead. Combining left ventricular hypertrophy with conduction abnormalities, ECG detection achieved 88% sensitivity, exceeding echocardiographic criteria alone (51.5%).</p><p><strong>Conclusion: </strong>The IVS4+919G>A variant is characterized by a progressive electrical phenotype dominated by conduction system disease preceding hypertrophy without excess major arrhythmic events. Electrocardiographic surveillance and phenotype-based risk stratification may be more informative than structural assessment alone for identifying individuals at risk of device therapy.Institutional Review Board: CMUH113-REC3-076.</p>","PeriodicalId":11981,"journal":{"name":"Europace","volume":" ","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149015942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary use of oesophageal temperature probes during left atrial ablation: results from an EHRA Scientific Initiatives Committee survey.","authors":"Arian Sultan, Piotr Futyma, Andreas Metzner, Giacomo Mugnai, Mark T Mills, Martin H Ruwald, Laura Perrotta, K R Julian Chun","doi":"10.1093/europace/euag255","DOIUrl":"10.1093/europace/euag255","url":null,"abstract":"","PeriodicalId":11981,"journal":{"name":"Europace","volume":"28 10","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of the GLORIA-AF Stroke Weighted Risk Score for patients with atrial fibrillation.","authors":"Yifan Xie, Wenhui Li, Yanda Meng, Tianjin Huang, Yalin Zheng, Menno V Huisman, Giuseppe Boriani, Tze-Fan Chao, Gregory Y H Lip","doi":"10.1093/europace/euag236","DOIUrl":"10.1093/europace/euag236","url":null,"abstract":"<p><strong>Aims: </strong>Accurate stroke risk stratification is central to anticoagulation decision-making in patients with atrial fibrillation (AF), but conventional scores may not fully capture risk heterogeneity. We aimed to develop and externally validate an interpretable weighted score using a time-to-event framework.</p><p><strong>Methods and results: </strong>GLORIA-AF Phase II/III data were used to evaluate 17 baseline predictors using LASSO-penalized Cox regression with stability selection; coefficients were converted into integer weights. Performance was assessed using discrimination, calibration, integrated discrimination improvement (IDI), continuous net reclassification improvement (NRI), and decision curve analysis. External validation was performed in EORP-AF and APHRS-AF registries. Among 20 517 patients included in the derivation cohort [mean (SD) age, 69.9 (10.3) years; 9196 women (44.8%)], 487 (2.4%) had stroke, and 17 397 (84.8%) were receiving anticoagulation at baseline. Ten selected predictors formed a 0-23-point score. The derived score achieved a C-index of 0.661 (95% CI, 0.636-0.685), higher than CHA2DS2-VA (0.626; P < 0.001), CHA2DS2-VASc (0.615; P < 0.001), and the unweighted score (P = 0.016), with no significant difference from the full Cox or machine learning models. In external validation (8309 patients; 147 strokes), the C-index was 0.652 (95% CI, 0.614-0.690) vs. 0.616 for CHA2DS2-VA (95% CI, 0.598-0.634; P < 0.001). IDI/NRI, calibration, and decision curve analyses supported improved risk differentiation, close calibration, and generally greater net benefit than CHA2DS2-VA. The score retained higher discrimination than CHA2DS2-VA among patients without baseline anticoagulation (P < 0.001).</p><p><strong>Conclusion: </strong>The GLORIA-AF Stroke Weighted Risk Score provides risk refinement beyond CHA2DS2-VA while retaining discrimination consistent with more complex models. External validation supports its transportability and potential adjunctive role in guideline-directed thromboembolic risk assessment.</p>","PeriodicalId":11981,"journal":{"name":"Europace","volume":" ","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13646627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148849925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanosecond pulsed field ablation for paroxysmal atrial fibrillation: feasibility, safety, and skeletal muscle activation.","authors":"Wenjie Li, Fanghui Li, Mingyang Tang, Xianjin Hu, Bangjiaxin Ren, Aobo Gong, Ying Cao, Zexi Li, Yifan Zhou, Qiancheng Zhao, Zulu Wang, Shuyan Li, Shaowen Liu, Guitang Yang, Rui Zeng","doi":"10.1093/europace/euag262","DOIUrl":"10.1093/europace/euag262","url":null,"abstract":"","PeriodicalId":11981,"journal":{"name":"Europace","volume":" ","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13629745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Outcomes of simplified left atrial appendage occlusion using the WATCHMAN FLX device: the ROSE-FLX study.","authors":"","doi":"10.1093/europace/euag287","DOIUrl":"10.1093/europace/euag287","url":null,"abstract":"","PeriodicalId":11981,"journal":{"name":"Europace","volume":"28 10","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of leadless pacing with the Micra VR beyond 10 years.","authors":"Constanze Puschmann, Hermann Blessberger, Justin Lacher, Hannah Rohringer, Jakob Bötscher, Julian Maier, Michael Gundendorfer, Stefan Schwarz, Christian Reiter, Jörg Kellermair, Juergen Kammler, Thomas Lambert, Karim Saleh, Clemens Steinwender","doi":"10.1093/europace/euag271","DOIUrl":"10.1093/europace/euag271","url":null,"abstract":"","PeriodicalId":11981,"journal":{"name":"Europace","volume":"28 10","pages":""},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13650481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}