Controversy: the blanking period after atrial fibrillation ablation is needed and should be maintained.

IF 7.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Europace Pub Date : 2025-10-07 DOI:10.1093/europace/euaf203
Helmut Pürerfellner, Stylianos Tzeis, John Mandrola
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Abstract

The concept of a post-ablation 'blanking period' (typically 90 days) has long served as a clinical and regulatory buffer during which atrial arrhythmia recurrences are not considered indicative of procedural failure. This period was originally justified by transient electrophysiological instability due to oedema, inflammation, and autonomic fluctuations. However, recent data-particularly in the era of continuous rhythm monitoring and novel energy sources such as pulsed field ablation-have challenged the biological and prognostic neutrality of early recurrences. Several studies now suggest that arrhythmia episodes within the blanking period, especially beyond the first 30 days, may strongly predict long-term recurrence, thereby questioning the utility of maintaining a fixed observational window. This EP Europace Controversy article presents opposing viewpoints on the necessity of the blanking period in modern practice. Dr Stelios Tzeis argues in favour of preserving the blanking period, citing its role in minimizing unnecessary re-intervention and ensuring standardized trial endpoints. Conversely, Dr John Mandrola advocates for shortening or abandoning the blanking period, proposing a more individualized approach guided by arrhythmia timing, symptom burden, and ablation modality. The introduction, authored by Prof. Helmut Pürerfellner, sets the stage by reviewing the historical rationale, emerging evidence, and practical implications of this ongoing debate. As ablation techniques evolve and data accrue, reassessing the blanking period becomes essential. This Controversy aims to inform clinical practice, future trial design, and shared decision-making by juxtaposing two expert perspectives on a timely and consequential topic in atrial fibrillation management.

Abstract Image

Abstract Image

争议:房颤消融后的空白期是需要的,应该维持。
消融后“空白期”(通常为90天)的概念长期以来一直作为临床和监管缓冲,在此期间,心房心律失常复发不被认为是手术失败的指示。这一时期最初是由水肿、炎症和自主神经波动引起的短暂电生理不稳定所证明的。然而,最近的数据,特别是在连续节律监测和脉冲场消融等新能源的时代,对早期复发的生物学和预后中立性提出了挑战。现在有几项研究表明,在空白期内,特别是在前30天之后,心律失常发作可能强烈预测长期复发,从而质疑维持固定观察窗口的效用。本文就空白期在现代实践中的必要性提出了不同的观点。斯泰利奥斯·泽伊斯博士主张保留空白期,理由是空白期在减少不必要的再干预和确保标准化试验终点方面的作用。相反,John Mandrola博士主张缩短或放弃空白期,提出一种更个性化的方法,以心律失常时间、症状负担和消融方式为指导。由Helmut p rerfellner教授撰写的引言通过回顾这一正在进行的辩论的历史依据、新出现的证据和实际意义,奠定了基础。随着烧蚀技术的发展和数据的积累,重新评估烧蚀时间变得至关重要。该争议旨在通过并置两名专家对房颤管理的及时和重要主题的观点,为临床实践、未来的试验设计和共同决策提供信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Europace
Europace 医学-心血管系统
CiteScore
10.30
自引率
8.20%
发文量
851
审稿时长
3-6 weeks
期刊介绍: EP - Europace - European Journal of Pacing, Arrhythmias and Cardiac Electrophysiology of the European Heart Rhythm Association of the European Society of Cardiology. The journal aims to provide an avenue of communication of top quality European and international original scientific work and reviews in the fields of Arrhythmias, Pacing and Cellular Electrophysiology. The Journal offers the reader a collection of contemporary original peer-reviewed papers, invited papers and editorial comments together with book reviews and correspondence.
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