发布求助
文献互助 智能选刊 最新文献

European Heart Journal最新文献

筛选
英文 中文
The European Society of Cardiology Council on Stroke: building the future of the multidisciplinary study of stroke. 欧洲心脏病学会卒中理事会：建立卒中多学科研究的未来。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf719
Gregory Y H Lip,Giulio Francesco Romiti,Marco Proietti,
{"title":"The European Society of Cardiology Council on Stroke: building the future of the multidisciplinary study of stroke.","authors":"Gregory Y H Lip,Giulio Francesco Romiti,Marco Proietti, ","doi":"10.1093/eurheartj/ehaf719","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf719","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"114 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From byte to bedside: how to ensure artificial intelligence is fit for clinical practice. 从字节到床边：如何确保人工智能适合临床实践。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf601
Judith Ozkan
{"title":"From byte to bedside: how to ensure artificial intelligence is fit for clinical practice.","authors":"Judith Ozkan","doi":"10.1093/eurheartj/ehaf601","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf601","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"98 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An evolving journey of cardiac rehabilitation. 心脏康复的进化之旅。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf713
David Carballo
{"title":"An evolving journey of cardiac rehabilitation.","authors":"David Carballo","doi":"10.1093/eurheartj/ehaf713","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf713","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"17 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subaortic caseous necrosis: insights from multimodality imaging. 主动脉下干酪样坏死：多模态成像的启示。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf756
He Li,Yifan Liu,Mingxing Xie
{"title":"Subaortic caseous necrosis: insights from multimodality imaging.","authors":"He Li,Yifan Liu,Mingxing Xie","doi":"10.1093/eurheartj/ehaf756","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf756","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"42 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The DORIAN GRAY project: bridging cardiovascular disease and cognitive decline. DORIAN GRAY项目：桥接心血管疾病和认知能力下降。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf575
Riccardo Proietti,Marianna Adamo,Mauro Massussi
{"title":"The DORIAN GRAY project: bridging cardiovascular disease and cognitive decline.","authors":"Riccardo Proietti,Marianna Adamo,Mauro Massussi","doi":"10.1093/eurheartj/ehaf575","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf575","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"10 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The cardiovascular professional of tomorrow: redefining basic research in the age of artificial intelligence. 未来的心血管专业人士：重新定义人工智能时代的基础研究。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf620
Judith Ozkan
{"title":"The cardiovascular professional of tomorrow: redefining basic research in the age of artificial intelligence.","authors":"Judith Ozkan","doi":"10.1093/eurheartj/ehaf620","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf620","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"98 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LRP5, a WNT signalling pathway receptor, and platelet activation WNT信号通路受体LRP5与血小板活化
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf772
Aureli Luquero, Noelia Pimentel, Gemma Vilahur, Maria Borrell-Pages, Lina Badimon
{"title":"LRP5, a WNT signalling pathway receptor, and platelet activation","authors":"Aureli Luquero, Noelia Pimentel, Gemma Vilahur, Maria Borrell-Pages, Lina Badimon","doi":"10.1093/eurheartj/ehaf772","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf772","url":null,"abstract":"Background and Aims Platelets are essential for haemostasis, thrombosis, and inflammation, with their functions controlled by receptor signalling pathways. This study examined the role of LRP5, a member of the Wnt signalling cascade, in platelet function and haemostasis. Methods Human platelets, as well as platelets isolated from wild-type (Wt) and Lrp5-deficient (Lrp5−/−) mice, were challenged with ADP, collagen, LRP5-specific inhibitors, and standard platelet inhibitor drugs. Results Both platelet aggregation (LTA) and flow-dependent platelet deposition on collagen-coated surfaces were significantly lower in Lrp5−/− than in Wt mice. In vivo carotid artery occlusion time measured by real-time blood flow monitoring was significantly prolonged in Lrp5−/− mice. While GPVI signalling remained intact, Lrp5−/− platelets displayed reduced α- and dense granule release after ADP stimulation, along with reduced membrane levels of purinergic receptors. VASP phosphorylation confirmed that P2Y12 downstream signalling pathway was dysfunctional in the LRP5-deficient platelets. Finally, human platelets express high levels of LRP5 and flow-mediated human platelet deposition and LTA was highly reduced by LRP5 inhibition. Under the experimental conditions tested, LRP5 deletion did not significantly affect coagulation nor induce bleeding. Conclusions These findings reveal for the first time that LRP5 plays a critical role in platelet adhesion and thrombus formation. Genetic deletion and biochemical inhibition of LRP5 markedly impair platelet aggregation and thrombosis in preclinical models, without major effects on haemostasis. Although further research is needed to evaluate its clinical applicability, LRP5 appears as a novel and actionable target to modulate platelet reactivity and thrombosis.","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"214 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Empowering the next generation: the importance of training early career cardiovascular professionals in scientific publishing. 授权下一代：在科学出版中培训早期职业心血管专业人员的重要性。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf740
C Fielder Camm
{"title":"Empowering the next generation: the importance of training early career cardiovascular professionals in scientific publishing.","authors":"C Fielder Camm","doi":"10.1093/eurheartj/ehaf740","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf740","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"24 3 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urinary tartaric acid and cardiovascular disease risk. 尿酒石酸与心血管疾病风险。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf761
Rosa M Lamuela-Raventós,Inés Domínguez-López,Ramon Estruch
{"title":"Urinary tartaric acid and cardiovascular disease risk.","authors":"Rosa M Lamuela-Raventós,Inés Domínguez-López,Ramon Estruch","doi":"10.1093/eurheartj/ehaf761","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf761","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"78 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized trials in cardiovascular, kidney, and metabolic diseases: rethinking late-phase drug development. 心血管、肾脏和代谢疾病的随机试验：重新思考晚期药物开发。
IF 39.3 1区 医学
European Heart Journal Pub Date : 2025-10-03 DOI: 10.1093/eurheartj/ehaf769
Brendon L Neuen,Hiddo J L Heerspink,Muthiah Vaduganathan
{"title":"Randomized trials in cardiovascular, kidney, and metabolic diseases: rethinking late-phase drug development.","authors":"Brendon L Neuen,Hiddo J L Heerspink,Muthiah Vaduganathan","doi":"10.1093/eurheartj/ehaf769","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf769","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"42 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信