European Heart Journal最新文献

Coffee drinking timing and mortality in US adults

IF 39.3 1区医学

European Heart Journal Pub Date : 2025-01-08 DOI: 10.1093/eurheartj/ehae871

Xuan Wang, Hao Ma, Qi Sun, Jun Li, Yoriko Heianza, Rob M Van Dam, Frank B Hu, Eric Rimm, JoAnn E Manson, Lu Qi

{"title":"Coffee drinking timing and mortality in US adults","authors":"Xuan Wang, Hao Ma, Qi Sun, Jun Li, Yoriko Heianza, Rob M Van Dam, Frank B Hu, Eric Rimm, JoAnn E Manson, Lu Qi","doi":"10.1093/eurheartj/ehae871","DOIUrl":"https://doi.org/10.1093/eurheartj/ehae871","url":null,"abstract":"Background and Aims To identify the patterns of coffee drinking timing in the US population and evaluate their associations with all-cause and cause-specific mortality. Methods This study included 40 725 adults from the National Health and Nutrition Examination Survey 1999–2018 who had complete information on dietary data and 1463 adults from the Women’s and Men’s Lifestyle Validation Study who had complete data on 7-day dietary record. Clustering analysis was used to identify patterns of coffee drinking timing. Results In this observational study, two distinct patterns of coffee drinking timing [morning type (36% of participants) and all-day-type patterns (14% of participants)] were identified in the National Health and Nutrition Examination Survey and were validated in the Women’s and Men’s Lifestyle Validation Study. During a median (interquartile range) follow-up of 9.8 (9.1) years, a total of 4295 all-cause deaths, 1268 cardiovascular disease deaths, and 934 cancer deaths were recorded. After adjustment for caffeinated and decaffeinated coffee intake amounts, sleep hours, and other confounders, the morning-type pattern, rather than the all-day-type pattern, was significantly associated with lower risks of all-cause (hazard ratio: .84; 95% confidential interval: .74–.95) and cardiovascular disease-specific (hazard ratio: .69; 95% confidential interval: .55–.87) mortality as compared with non-coffee drinking. Coffee drinking timing significantly modified the association between coffee intake amounts and all-cause mortality (P-interaction = .031); higher coffee intake amounts were significantly associated with a lower risk of all-cause mortality in participants with morning-type pattern but not in those with all-day-type pattern. Conclusions Drinking coffee in the morning may be more strongly associated with a lower risk of mortality than drinking coffee later in the day.","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"2020 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142935920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

24-hour ambulatory blood pressure monitoring: a game changer in the management of reflex syncope?

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-01-03 DOI: 10.1093/eurheartj/ehae872

Peter Mitro

引用次数: 0

Atrial fibrillation ablation timing: where is the sweet spot?

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-01-03 DOI: 10.1093/eurheartj/ehae892

Jonathan M Kalman, Peter M Kistler, Gerhard Hindricks, Prashanthan Sanders

{"title":"Atrial fibrillation ablation timing: where is the sweet spot?","authors":"Jonathan M Kalman, Peter M Kistler, Gerhard Hindricks, Prashanthan Sanders","doi":"10.1093/eurheartj/ehae892","DOIUrl":"https://doi.org/10.1093/eurheartj/ehae892","url":null,"abstract":"Convincing evidence for the efficacy of ablation as first-line therapy in paroxysmal AF (PAF) and its clear superiority to medical therapy for rhythm control in both PAF and persistent AF (PsAF) has generated considerable interest in the optimal timing of ablation. Based on this data, there is a widespread view that the principle of 'the earlier the better' should be generally applied. However, the natural history of AF is highly variable and non-linear, and for this reason, it is difficult to be emphatic that all patients are best served by ablation early after their initial AF episodes. Sufficient evidence exists to indicate a conservative approach is reasonable in patients with infrequent and non-progressive episodes (i.e. absence of progressive increase in burden culminating in PsAF) in whom symptoms remain mild and well-controlled. A conservative management phase should be marked by assiduous attention to risk factor modification, changes in frequency and duration of AF episodes, and patient preferences. If and when AF does begin to progress, accumulating evidence indicates that early ablation accompanied by ongoing attention to risk factors provides the best outcomes.","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":37.6,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Weekly Journal Scan: FINEARTS-HF supports the role of aldosterone antagonism in the management of heart failure with mildly reduced or preserved ejection fraction. 每周期刊扫描：FINEARTS-HF 支持醛固酮拮抗剂在治疗射血分数轻度降低或保留的心力衰竭中的作用。

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-01-03 DOI: 10.1093/eurheartj/ehae679

Massimo Volpe, Leonarda Galiuto

引用次数: 0

Gold standard: Karin Sipido honoured for pioneering work. 黄金标准：卡琳-西皮多（Karin Sipido）因开创性工作而获奖。

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-01-03 DOI: 10.1093/eurheartj/ehae741

Judith Ozkan

引用次数: 0

Non-vitamin K oral anticoagulants in valvular heart disease before surgery: a tale of bridging vs. no bridging. 瓣膜性心脏病术前使用非维生素 K 口服抗凝剂：桥接与不桥接的故事。

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-01-03 DOI: 10.1093/eurheartj/ehae615

Raffaele De Caterina, Hugo Ten Cate, Vittorio Pengo

引用次数: 0

Bleeding risk using non-steroidal anti-inflammatory drugs with anticoagulants after venous thromboembolism: a nationwide Danish study. 静脉血栓栓塞后使用非甾体抗炎药和抗凝剂的出血风险：一项全国性的丹麦研究。

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-01-03 DOI: 10.1093/eurheartj/ehae736

Søren Riis Petersen, Kasper Bonnesen, Erik Lerkevang Grove, Lars Pedersen, Morten Schmidt

{"title":"Bleeding risk using non-steroidal anti-inflammatory drugs with anticoagulants after venous thromboembolism: a nationwide Danish study.","authors":"Søren Riis Petersen, Kasper Bonnesen, Erik Lerkevang Grove, Lars Pedersen, Morten Schmidt","doi":"10.1093/eurheartj/ehae736","DOIUrl":"10.1093/eurheartj/ehae736","url":null,"abstract":"Background and aims: The bleeding risk of using non-steroidal anti-inflammatory drugs (NSAIDs) in patients treated with oral anticoagulants for venous thromboembolism (VTE) remains unclear.Methods: A nationwide cohort study of 51 794 VTE patients initiating oral anticoagulants between 1 January 2012 and 31 December 2022 was conducted. Time-dependent multivariate cause-specific Cox regression was used to compute adjusted hazard ratios between NSAID use and hospital-diagnosed bleeding episodes.Results: Event rates for any bleeding per 100 person-years were 3.5 [95% confidence interval (CI), 3.4-3.7] during periods without NSAID use and 6.3 (95% CI, 5.1-7.9) during periods with NSAID use (number needed to harm = 36 patients treated for 1 year). Compared with non-use, the adjusted hazard ratios for any bleeding associated with NSAID use were 2.09 (95% CI, 1.67-2.62) overall, 1.79 (95% CI, 1.36-2.36) for ibuprofen, 3.30 (95% CI, 1.82-5.97) for diclofenac, and 4.10 (95% CI, 2.13-7.91) for naproxen. Compared with non-use, the adjusted hazard ratios associated with NSAID use were 2.24 (95% CI, 1.61-3.11) for gastrointestinal bleeding, 3.22 (95% CI, 1.69-6.14) for intracranial bleeding, 1.36 (95% CI, .67-2.77) for thoracic and respiratory tract bleeding, 1.57 (95% CI, .98-2.51) for urinary tract bleeding, and 2.99 (95% CI, 1.45-6.18) for anaemia caused by bleeding. Results were consistent for anticoagulant and VTE subtypes.Conclusions: Patients treated with oral anticoagulants for VTE had a more than two-fold increased bleeding rate when using NSAIDs. This increased bleeding rate was not restricted to the gastrointestinal tract.","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"58-68"},"PeriodicalIF":37.6,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thrombus straddling a patent foramen ovale. 横跨卵圆孔的血栓。

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-01-03 DOI: 10.1093/eurheartj/ehae433

Na Sun, Yan Cong, Bing-Xiang Wu

引用次数: 0

Cardio-renal risk stratification and acute kidney injury in acute coronary syndromes. 急性冠状动脉综合征的心肾风险分层和急性肾损伤。

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-01-03 DOI: 10.1093/eurheartj/ehae717

Luca Crisanti, Christian Mueller

引用次数: 0

Family matters: health policies to tackle cardiomyopathies across Europe. 家庭问题：欧洲各地应对心肌病的卫生政策。