European Heart Journal最新文献

{"title":"From individual markers to reformulable processing signatures in hypertension prevention.","authors":"Yue-Zhong Huang","doi":"10.1093/eurheartj/ehag842","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag842","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing co-occurrence patterns of potentially disease-relevant markers of ultra-processed food.","authors":"Kathrin Marie Krost, Gerrit Eichner, Nathalie Judith Eise","doi":"10.1093/eurheartj/ehag843","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag843","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond clinical phenotypes: endotype-specific environmental cardiovascular susceptibility.","authors":"Masanobu Ishii, Taishi Nakamura, Kenichi Tsujita","doi":"10.1093/eurheartj/ehag814","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag814","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the lifestyle paradigm: environmental triggers and susceptible cardiovascular phenotypes.","authors":"Shazina Saeed, Priyadarshini Arambam, Upendra Kaul","doi":"10.1093/eurheartj/ehag813","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag813","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracoronary imaging to assess atherosclerosis and to guide percutaneous coronary intervention.","authors":"Rocco Vergallo, Gregg W Stone, Thomas W Johnson, Joo Myung Lee, Lorenz Räber, Ik-Kyung Jang","doi":"10.1093/eurheartj/ehag824","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag824","url":null,"abstract":"<p><p>Intracoronary imaging has become an important tool for the in vivo assessment of coronary atherosclerosis and for guiding percutaneous coronary intervention. By enabling high-resolution visualization of coronary anatomy, these modalities allow for more accurate lesion characterization, precise stent sizing, and optimized procedural strategies. In recent years, multiple randomized controlled trials have demonstrated that imaging-guided percutaneous coronary intervention reduces major adverse cardiac events (including cardiac death, myocardial infarction, and repeat revascularization), particularly in complex clinical and anatomical settings. This state-of-the-art review synthesizes contemporary evidence supporting the use of intravascular ultrasound and optical coherence tomography to guide percutaneous coronary intervention and improve clinical outcomes, drawing from recent trial data and current guideline recommendations. Special emphasis is placed on complex lesion subsets, such as left main coronary artery disease and other complex bifurcation lesions, calcified lesions, long lesions, and scenarios involving patients at heightened risk, such as those with acute coronary syndrome. Finally, this review considers the strengths and limitations of intracoronary imaging, as well as unresolved questions and priority areas for future research aimed at further improving patient outcomes.</p>","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photon-counting computed tomography depicts seven multifocal ulcer-like projections with jet-like blood flow in aortic dissection.","authors":"Qinglin Du, Yifan Shen, Jiayu Sun","doi":"10.1093/eurheartj/ehag844","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag844","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporary mechanical circulatory support in cardiogenic shock.","authors":"Alaide Chieffo, Mario Iannaccone, Christian Hassager, Dariusz Dudek, Alain Combes, Mario Gramegna, Sigrun Halvorsen, Kurt Huber, Vijay Kunadian, Jiri Maly, Jacob Eifer Møller, Federico Pappalardo, Giuseppe Tarantini, Guido Tavazzi, Holger Thiele, Christophe Vandenbriele, Nicolas M Van Mieghem, Pascal Vranckx, Steffen Desch, Nikos Werner, Susanna Price","doi":"10.1093/eurheartj/ehag708","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag708","url":null,"abstract":"<p><p>Cardiogenic shock (CS) remains a heterogeneous syndrome associated with persistently high mortality despite advances in temporary mechanical circulatory support. One recent randomized controlled trial suggested a mortality benefit of a percutaneous microaxial flow pump in a cohort of patients with ST-elevation myocardial infarction complicated by CS, whereas routine veno-arterial extracorporeal membrane oxygenation in populations with acute myocardial infarction complicated by CS has not improved survival and is associated with higher complication rates. These findings underscore the importance of phenotype-driven patient selection, incorporating the Society for Cardiovascular Angiography and Interventions (SCAI) and Shock Academic Research Consortium (SHARC) classifications to guide device selection, timing, escalation, and de-escalation. This clinical consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) and the Association for Acute CardioVascular Care (ACVC) of the European Society of Cardiology (ESC) updates the 2020 expert consensus document and provides updated practical guidance based on the recent evidence on the use of temporary mechanical circulatory support in acute myocardial infarction complicated by CS. Emphasis is placed on patient/device selection according to recent evidence, multidisciplinary shock teams, regionalized hub-and-spoke systems, structured protocols for escalation and futility, and the integration of contemporary trial data and best practices to optimize outcomes in this high-risk population.</p>","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 'ten commandments' for the 2025 European Society of Cardiology guidelines on myocarditis and pericarditis.","authors":"Massimo Imazio, Jeanette Schulz-Menger","doi":"10.1093/eurheartj/ehag766","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag766","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genotype and arrhythmic risk in dilated cardiomyopathy.","authors":"Kishan Padalia, Alessandra Fornaro, Brian Claggett, Max Jason, Sarah Moritz, Kristen Medo, Sharon Graw, Sophie Hespe, Jodie Ingles, Carolyn Y Ho, Adam S Helms, Supriya Shore, Gianfranco Sinagra, Marco Merlo, Sadiya S Khan, Kim Lin, Iacopo Olivotto, Anjali Owens, Matthew Wheeler, Lynne Stevenson, Nosheen Reza, Joseph Rossano, Alessia Paldino, Job A J Verdonschot, Matthew R G Taylor, Upasana Tayal, Stephane R B Heymans, Sanjay Prasad, Neal K Lakdawala, Victoria N Parikh, Luisa Mestroni, Lisa D Wilsbacher","doi":"10.1093/eurheartj/ehag648","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag648","url":null,"abstract":"<p><strong>Background and aims: </strong>Dilated cardiomyopathy (DCM) presents with variable risk of life-threatening arrhythmias. Genetic diagnosis guides sudden death prevention strategies, but risk magnitude for arrhythmogenic genes remains unknown. This study leveraged the international Sarcomeric Human Cardiomyopathy Registry (SHaRe) to address this gap and improve risk stratification.</p><p><strong>Methods: </strong>Effects of pathogenic/likely pathogenic (P/LP) variants in genes associated with DCM and ventricular arrhythmia on clinical events were analysed in DCM-SHaRe patients. Patients were stratified by presence of a P/LP variant in a high-arrhythmogenic risk gene (LMNA, DSP, FLNC, RBM20, PLN, SCN5A, DES, TMEM43), a low-arrhythmogenic risk gene (TTN, TNNT2, MYH7, others), or gene-elusive. Outcomes included age-, sex-, and baseline left ventricular ejection fraction (LVEF)-adjusted risk of major ventricular arrhythmia (MVA), atrial fibrillation (AF), heart failure (HF), death, and their composite.</p><p><strong>Results: </strong>Among 2660 genotyped adults with DCM (mean diagnosis age 47 ± 15 years, 39.8% female), 434 (16%) had P/LP variants in high-arrhythmogenic genes, 451 (17%) in low-arrhythmogenic genes, and 1775 (67%) were gene-elusive. Compared with gene-elusive patients, patients with high-arrhythmogenic P/LP variants showed increased MVA [hazard ratio (HR) 3.25, 95% confidence interval (CI) 2.63-4.01], AF (HR 2.42, 95% CI 1.96-2.98), HF (HR 2.46, 95% CI 1.89-3.19), and composite (HR 1.97, 95% CI 1.69-2.29) risk, which remained significant after adjusting for age, sex, and LVEF. Patients with high-arrhythmogenic P/LP variants and LVEF ≥ 50% maintained increased MVA (HR 2.36, 95% CI 1.59-3.51) and composite (HR 1.63, 95% CI 1.25-2.12) risk.</p><p><strong>Conclusions: </strong>Genetic testing enables powerful risk stratification for arrhythmias and HF in DCM independent of age, sex, or LVEF.</p>","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Standard-dose direct oral anticoagulants for Asian patients with atrial fibrillation: the definitive case from COMBINE AF.","authors":"","doi":"10.1093/eurheartj/ehag847","DOIUrl":"https://doi.org/10.1093/eurheartj/ehag847","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":45.3,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}