European Heart Journal最新文献

{"title":"Weekly Journal Scan: Extending anticoagulation beyond 6 months after venous thromboembolism in patients with active cancer. Is low-dose apixaban the answer?","authors":"Mattia Galli, Carlo Patrono","doi":"10.1093/eurheartj/ehaf346","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf346","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":37.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statins beat device-related in-stent neo-atherosclerosis: pathophysiology reigns supreme.","authors":"William Wijns, Shengxian Tu","doi":"10.1093/eurheartj/ehaf295","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf295","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":37.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An update on the Council for Cardiology Practice of the European Society of Cardiology.","authors":"Luigina Guasti,Konstantinos Toutouzas,Ruxandra Christodorescu","doi":"10.1093/eurheartj/ehaf123","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf123","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"35 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finerenone effects on biomarkers: an analysis from the FIGARO-DKD trial.","authors":"Mario Berger,Aidan MacNamara,João Pedro Ferreira,Peter Kolkhof,Sebastian Voss,Adam Skubala,Andrea Scalise,Laura Goea,Richard Nkulikiyinka,Bertram Pitt,Joachim Hanno Ix,Peter Rossing,Richard John Mark Coward,Faiez Zannad,Hiddo J L Heerspink","doi":"10.1093/eurheartj/ehaf316","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf316","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"19 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior left pericardiotomy in cardiac surgery and outcomes: PALACS-EF trial extended follow-up.","authors":"Mario Gaudino,Lamia Harik,Bjorn Redfors,Jordan Leith,Alexander C Gregg,Jessica Kim,Rachel Heise,Lisa Q Rong,Sigrid Sandner,Antonino Di Franco,Charles A Mack,Christopher Lau,Tommaso Sanna,Giovanni J Soletti,Jonathan W Weinsaft,Gianni D Angelini,John H Alexander,Leonard N Girardi","doi":"10.1093/eurheartj/ehaf325","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf325","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"136 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beta-blocker interruption effects on blood pressure and heart rate after myocardial infarction: the AβYSS trial.","authors":"Niki Procopi,Michel Zeitouni,Mathieu Kerneis,Guillaume Cayla,Emile Ferrari,Grégoire Range,Etienne Puymirat,Nicolas Delarche,Paul Guedeney,Farzin Beygui,Laurent Desprets,Jean-Louis Georges,Thomas Bochaton,François Schiele,Grégory Ducrocq,Marie Hauguel-Moreau,Raphaelle Dumaine,Michel S Slama,Laurent Payot,Mohamad El Kasty,Karim Aacha,Abdourahmane Diallo,Xavier Girerd,Eric Vicaut,Johanne Silvain,Gilles Montalescot","doi":"10.1093/eurheartj/ehaf170","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf170","url":null,"abstract":"BACKGROUND AND AIMSThis study aims to report the effects of β-blocker interruption on blood pressure (BP) and heart rate (HR) in the AβYSS trial where patients were randomized to interruption or continuation of β-blocker treatment after a myocardial infarction (MI).METHODSChanges in HR and BP from baseline to post-randomization are reported using linear mixed repeated model, in the 3698 patients of the AβYSS trial with a median follow-up of 3.0 years. Additionally, changes in HR and BP and the impact on the primary endpoint (death, MI, stroke, hospitalization for cardiovascular reason) in the pre-specified subgroups of patients with or without history of hypertension were assessed using linear mixed repeated and adjusted Cox proportional hazards model, respectively.RESULTSβ-blocker interruption was associated with significant increase {least square mean difference [95% confidence interval (CI)]} in systolic BP [+3.7 (2.6, 4.8) mmHg, P < .001], diastolic BP [+3.3 (2.6, 4.0) mmHg, P < .001], and resting HR [+10 [9, 11) b.p.m., P < .001] at 6 months that persisted over the duration of follow-up despite an increase in antihypertensive drugs in the β-blocker interruption group. The effects were observed in both hypertensive (43% of the population) and non-hypertensive patients. Hypertensive patients were at higher risk of events (25.8% vs. 19.2%) as compared with patients without hypertension (adjusted hazard ratio 1.18, 95% CI 1.01-1.36, P = .03). Patients with hypertension had a particularly marked increase in the primary endpoint (risk difference 5.02%, 0.72%-9.32%, P = .014) when randomized to β-blocker interruption.CONCLUSIONSInterruption of β-blocker treatment after an uncomplicated MI led to a sustained increase in BP and HR, with potentially deleterious effects on outcomes, especially in patients with history of hypertension.","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"45 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of ventricular arrhythmic outcomes in suspected cardiac sarcoidosis: a comparison of cardiovascular magnetic resonance phenotyping vs. societal recommendations for implantable cardioverter-defibrillator placement","authors":"Harold Mathijssen, Parag H Bawaskar, Yogita Rochlani, Issac Georgy, Pal Satyajit Singh Athwal, Yugene Guo, Daniel Pollmann, Jeremy Markowitz, Lisa Von Wald, Henri Roukoz, David Perlman, Maneesh Bhargava, Leandro Slipczuk, Annalisa Filtz, Julio Andres Ovalle Ramos, Saurabhi Samant, Sanya Chhikara, Francesco Castagna, Marcel Veltkamp, Fatima Akdim, Annelies L M Bakker, Marco C Post, Chetan Shenoy","doi":"10.1093/eurheartj/ehaf338","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf338","url":null,"abstract":"Background and Aims Implementing societal recommendations for primary prevention implantable cardioverter-defibrillators (ICDs) in cardiac sarcoidosis requires an accurate diagnosis. However, cardiac sarcoidosis diagnostic schemes are inconsistent and often produce conflicting results. This study aimed to compare the discriminative accuracy of cardiovascular magnetic resonance imaging (CMR) phenotyping with the societal recommendations for predicting long-term ventricular arrhythmic outcomes in patients with suspected cardiac sarcoidosis, regardless of their diagnostic status. Methods This multicentre study included patients with histology-supported sarcoidosis who underwent CMR for suspected cardiac involvement and were ineligible for secondary prevention ICDs. The study outcome was a composite of fatal or life-threatening ventricular arrhythmias. Outcomes were compared based on eligibility for ICDs by societal recommendations and CMR phenotyping. Results Among 1514 patients, 84 experienced the study outcome during a median follow-up of 4.5 years and a maximum follow-up of 10 years. The high-risk CMR phenotype was associated with higher 5- and 10-year incidences of the outcome (24.0% and 35.0%, respectively) compared with those who met societal recommendations. Patients with low-risk phenotypes had lower incidences (0.7% and 2.6%). Cardiovascular magnetic resonance imaging phenotyping outperformed societal recommendations in discriminative accuracy, with areas under the curve of 0.861 and 0.776 for 5- and 10-year outcomes, respectively. Additionally, CMR phenotyping had the highest adjusted subdistribution hazard ratio (19.8) for the study outcome. Conclusions In patients with suspected cardiac sarcoidosis, CMR phenotyping showed greater discriminative accuracy than societal recommendations for predicting fatal or life-threatening ventricular arrhythmias, suggesting that it may be more effective at identifying candidates for primary prevention ICDs.","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"7 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staring into the AβYSS: how many pills and for how long after myocardial infarction?","authors":"John G F Cleland","doi":"10.1093/eurheartj/ehaf226","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf226","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"57 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The year in cardiovascular medicine 2024: the top 10 papers in diabetes and metabolic disorders.","authors":"Francesco Cosentino, Christopher Paul Cannon, Nikolaus Marx","doi":"10.1093/eurheartj/ehaf280","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf280","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":37.6,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family history of aortic dissection in fibrillin-1 pathogenic variant.","authors":"Maria Tchitchinadze,Olivier Milleron,Ludivine Eliahou,Sabrine Jadoui,Nadia Ould Ouali,Nadine Hanna,Pauline Arnaud,Jacques Ropers,Catherine Boileau,Laurent Gouya,Guillaume Jondeau","doi":"10.1093/eurheartj/ehaf321","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf321","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"40 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}