European Heart Journal最新文献_第10页

Non-traditional risk factors for atrial fibrillation: epidemiology, mechanisms, and strategies. 房颤的非传统危险因素：流行病学、机制和策略。

IF 37.6 1区医学

European Heart Journal Pub Date : 2025-03-03 DOI: 10.1093/eurheartj/ehae887

Yingli Lu, Ying Sun, Lingli Cai, Bowei Yu, Yuying Wang, Xiao Tan, Heng Wan, Dachun Xu, Junfeng Zhang, Lu Qi, Prashanthan Sanders, Ningjian Wang

{"title":"Non-traditional risk factors for atrial fibrillation: epidemiology, mechanisms, and strategies.","authors":"Yingli Lu, Ying Sun, Lingli Cai, Bowei Yu, Yuying Wang, Xiao Tan, Heng Wan, Dachun Xu, Junfeng Zhang, Lu Qi, Prashanthan Sanders, Ningjian Wang","doi":"10.1093/eurheartj/ehae887","DOIUrl":"10.1093/eurheartj/ehae887","url":null,"abstract":"<p><p>Atrial fibrillation (AF) has become the pre-dominant arrhythmia worldwide and is associated with high morbidity and mortality. Its pathogenesis is intricately linked to the deleterious impact of cardiovascular risk factors, emphasizing the pivotal imperative for early detection and mitigation strategies targeting these factors for the prevention of primary AF. While traditional risk factors are well recognized, an increasing number of novel risk factors have been identified in recent decades. This review explores the emerging non-traditional risk factors for the primary prevention of AF, including unhealthy lifestyle factors in current society (sleep, night shift work, and diet), biomarkers (gut microbiota, hyperuricaemia, and homocysteine), adverse conditions or diseases (depression, epilepsy, clonal haematopoiesis of indeterminate potential, infections, and asthma), and environmental factors (acoustic pollution and other environmental factors). Unlike traditional risk factors, individuals have limited control over many of these non-traditional risk factors, posing challenges to conventional prevention strategies. The purpose of this review is to outline the current evidence on the associations of non-traditional risk factors with new-onset AF and the potential mechanisms related to these risk factors. Furthermore, this review aims to explore potential interventions targeting these risk factors at both the individual and societal levels to mitigate the growing burden of AF, suggesting guideline updates for primary AF prevention.</p>","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"784-804"},"PeriodicalIF":37.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}