{"title":"AI-ECG and prediction of new atrial fibrillation: when the heart tells the age.","authors":"Antonio H Ribeiro, Antonio Luiz P Ribeiro","doi":"10.1093/eurheartj/ehae809","DOIUrl":"https://doi.org/10.1093/eurheartj/ehae809","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":37.6,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Binge drinking and arrhythmias: a sobering message.","authors":"Nicole Evans, Aleksandr Voskoboinik","doi":"10.1093/eurheartj/ehae709","DOIUrl":"10.1093/eurheartj/ehae709","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"4950-4952"},"PeriodicalIF":37.6,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Another piece in the puzzle of atrial fibrillation risk: clinical, genetic, and electrocardiogram-based artificial intelligence.","authors":"Shinwan Kany, Patrick T Ellinor, Shaan Khurshid","doi":"10.1093/eurheartj/ehae691","DOIUrl":"10.1093/eurheartj/ehae691","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"4935-4937"},"PeriodicalIF":37.6,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Weekly Journal Scan: Risk factors for recurrent ischaemic stroke in patients with atrial fibrillation on oral anticoagulation.","authors":"Leonarda Galiuto, Carlo Patrono","doi":"10.1093/eurheartj/ehae630","DOIUrl":"10.1093/eurheartj/ehae630","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"4977-4978"},"PeriodicalIF":37.6,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stroke risk in device-detected atrial fibrillation is modulated by the continuum of vascular disease burden.","authors":"Dominik Linz, Sevasti-Maria Chaldoupi","doi":"10.1093/eurheartj/ehae797","DOIUrl":"10.1093/eurheartj/ehae797","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"4917-4919"},"PeriodicalIF":37.6,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Focus on atrial fibrillation: role of atrioventricular node ablation, prediction by deep learning, and anticoagulation in device-detected arrhythmia.","authors":"Filippo Crea","doi":"10.1093/eurheartj/ehae826","DOIUrl":"https://doi.org/10.1093/eurheartj/ehae826","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"45 46","pages":"4873-4877"},"PeriodicalIF":37.6,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gilbert Jabbour, Alexis Nolin-Lapalme, Olivier Tastet, Denis Corbin, Paloma Jordà, Achille Sowa, Jacques Delfrate, David Busseuil, Julie G Hussin, Marie-Pierre Dubé, Jean-Claude Tardif, Léna Rivard, Laurent Macle, Julia Cadrin-Tourigny, Paul Khairy, Robert Avram, Rafik Tadros
{"title":"Prediction of incident atrial fibrillation using deep learning, clinical models, and polygenic scores.","authors":"Gilbert Jabbour, Alexis Nolin-Lapalme, Olivier Tastet, Denis Corbin, Paloma Jordà, Achille Sowa, Jacques Delfrate, David Busseuil, Julie G Hussin, Marie-Pierre Dubé, Jean-Claude Tardif, Léna Rivard, Laurent Macle, Julia Cadrin-Tourigny, Paul Khairy, Robert Avram, Rafik Tadros","doi":"10.1093/eurheartj/ehae595","DOIUrl":"10.1093/eurheartj/ehae595","url":null,"abstract":"<p><strong>Background and aims: </strong>Deep learning applied to electrocardiograms (ECG-AI) is an emerging approach for predicting atrial fibrillation or flutter (AF). This study introduces an ECG-AI model developed and tested at a tertiary cardiac centre, comparing its performance with clinical models and AF polygenic score (PGS).</p><p><strong>Methods: </strong>Electrocardiograms in sinus rhythm from the Montreal Heart Institute were analysed, excluding those from patients with pre-existing AF. The primary outcome was incident AF at 5 years. An ECG-AI model was developed by splitting patients into non-overlapping data sets: 70% for training, 10% for validation, and 20% for testing. The performance of ECG-AI, clinical models, and PGS was assessed in the test data set. The ECG-AI model was externally validated in the Medical Information Mart for Intensive Care-IV (MIMIC-IV) hospital data set.</p><p><strong>Results: </strong>A total of 669 782 ECGs from 145 323 patients were included. Mean age was 61 ± 15 years, and 58% were male. The primary outcome was observed in 15% of patients, and the ECG-AI model showed an area under the receiver operating characteristic (AUC-ROC) curve of .78. In time-to-event analysis including the first ECG, ECG-AI inference of high risk identified 26% of the population with a 4.3-fold increased risk of incident AF (95% confidence interval: 4.02-4.57). In a subgroup analysis of 2301 patients, ECG-AI outperformed CHARGE-AF (AUC-ROC = .62) and PGS (AUC-ROC = .59). Adding PGS and CHARGE-AF to ECG-AI improved goodness of fit (likelihood ratio test P < .001), with minimal changes to the AUC-ROC (.76-.77). In the external validation cohort (mean age 59 ± 18 years, 47% male, median follow-up 1.1 year), ECG-AI model performance remained consistent (AUC-ROC = .77).</p><p><strong>Conclusions: </strong>ECG-AI provides an accurate tool to predict new-onset AF in a tertiary cardiac centre, surpassing clinical and PGS.</p>","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"4920-4934"},"PeriodicalIF":37.6,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accelerated pacing as a treatment for heart failure with preserved ejection fraction and atrial fibrillation?","authors":"Markus Meyer","doi":"10.1093/eurheartj/ehae766","DOIUrl":"10.1093/eurheartj/ehae766","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"4965-4967"},"PeriodicalIF":37.6,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}