European journal of obstetrics, gynecology, and reproductive biology最新文献

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Epidural analgesia in small for gestational age and growth restricted fetuses: Impact on emergency delivery for presumed fetal distress 小胎龄和生长受限胎儿的硬膜外镇痛:对推定胎儿窘迫的紧急分娩的影响。
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2026-01-05 DOI: 10.1016/j.ejogrb.2026.114940
Anna Fichera , Chiara Pedretti , Nicola Fratelli , Adriana Valcamonico , Daniela Recupero , Andrea Coelli , Angelica Fiorini , Antonino D’Ippolito , Franco E. Odicino
{"title":"Epidural analgesia in small for gestational age and growth restricted fetuses: Impact on emergency delivery for presumed fetal distress","authors":"Anna Fichera ,&nbsp;Chiara Pedretti ,&nbsp;Nicola Fratelli ,&nbsp;Adriana Valcamonico ,&nbsp;Daniela Recupero ,&nbsp;Andrea Coelli ,&nbsp;Angelica Fiorini ,&nbsp;Antonino D’Ippolito ,&nbsp;Franco E. Odicino","doi":"10.1016/j.ejogrb.2026.114940","DOIUrl":"10.1016/j.ejogrb.2026.114940","url":null,"abstract":"<div><h3>Introduction</h3><div>Epidural analgesia (EDA) is widely used for pain relief during labor. Concerns have been raised about its potential association with an increased risk of emergency delivery for presumed fetal compromise, particularly in fetuses with low birth weight. This study aimed to evaluate whether EDA increases the risk of emergency delivery for suspected fetal distress in small-for-gestational-age and fetal growth restricted fetuses.</div></div><div><h3>Methods</h3><div>Retrospective cohort study conducted on singleton pregnancies with prenatal diagnosis of small-for-gestational-age or fetal growth restricted fetuses, delivering at ≥ 36 + 0 weeks at a tertiary care center between January 2020 and January 2024. The primary exposure was EDA; the primary outcome was emergency cesarean section or vacuum-assisted delivery due to presumed fetal distress, based on cardiotocographic findings. The secondary outcome was the incidence of a composite neonatal outcome defined as the occurrence of at least one of umbilical artery pH &lt; 7.00, base excess &lt; –12 mEq/L, 5-minute Apgar score &lt; 7, or NICU admission. The two groups (EDA vs. non-EDA) were compared using the chi-square test for categorical variables and the Mann–Whitney <em>U</em> test for continuous variables. Multivariate logistic regression was used to control for confounders.</div></div><div><h3>Results</h3><div>Among 310 eligible deliveries, 135 (43.5 %) received EDA. Emergency delivery for suspected fetal distress occurred in 16.5 % of cases. There were no significant differences in emergency delivery rates between the EDA and non-EDA groups (15.56 % vs 17.14 %; p = 0.759), nor within the small-for-gestational-age (13.4 % vs 13.9 %; p = 0.896) and the growth restricted fetuses (21.5 % vs 22.4 %; p = 0.874) subgroups. No significant difference in the composite adverse neonatal outcome was observed between the EDA and non-EDA groups (8.15 % vs 7.43 %; p = 0.814). Multivariate analysis confirmed no association between EDA and emergency delivery (p = 0.600), whereas nulliparity (p = 0.024) and U/C ratio &gt; 0.8 (p = 0.004) emerged as independent risk factors. Composite neonatal outcomes were similar between groups.</div></div><div><h3>Conclusions</h3><div>In this cohort of well-characterized small-for-gestational-age and fetal growth restricted fetuses, EDA was not associated with an increased risk of emergency delivery for suspected fetal distress. Individualized patient assessment and tailored management of labor analgesia remain crucial to ensure maternal and fetal safety.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114940"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145917400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diurnal variation in urine protein-to-creatinine ratio among pregnant women with and without hypertensive disorders: A retrospective clinical study 有或无高血压疾病孕妇尿蛋白与肌酐比值的日变化:一项回顾性临床研究。
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2025-12-13 DOI: 10.1016/j.ejogrb.2025.114893
Cami Lehavi , Amir Naeh , Eiman Shalabna , Rinat Gabbay-Benziv , Esther Maor-Sagie
{"title":"Diurnal variation in urine protein-to-creatinine ratio among pregnant women with and without hypertensive disorders: A retrospective clinical study","authors":"Cami Lehavi ,&nbsp;Amir Naeh ,&nbsp;Eiman Shalabna ,&nbsp;Rinat Gabbay-Benziv ,&nbsp;Esther Maor-Sagie","doi":"10.1016/j.ejogrb.2025.114893","DOIUrl":"10.1016/j.ejogrb.2025.114893","url":null,"abstract":"<div><h3>Objective</h3><div>Physiological proteinuria occurs in approximately 8 % of normal pregnancies due to increased glomerular filtration and altered tubular reabsorption. Hypertensive disorders complicate 3–8 % of pregnancies and are associated with adverse outcomes. Although 24-hour urine collection is the traditional standard for assessing proteinuria, it is cumbersome and time-consuming. The urine protein-to-creatinine ratio (Upcr) has largely replaced it owing to its convenience and strong correlation with 24-hour values. However, Upcr relies on random sampling and may be influenced by diurnal variation. This study aimed to assess and compare Upcr diurnal variability in normotensive versus hypertensive singleton pregnancies.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted of all Upcr tests performed between January 2021 and March 2024 at a single university-affiliated center. Tests were ordered following a positive urine dipstick during routine screening. Only the first test per pregnancy was included. Upcr values were compared by sampling time—day (07:00–22:59) versus night (23:00–06:59)—and by subsequent development of hypertensive disorders. Differences were analyzed using the Kruskal–Wallis test.</div></div><div><h3>Results</h3><div>Among 13,054 deliveries, 1,317 (10 %) underwent Upcr testing; 35.8 % developed hypertensive disorders. Most samples were collected during the day (1,121 vs. 196 at night). Hypertensive pregnancies exhibited higher Upcr levels regardless of sampling time. In this group, daytime Upcr values were significantly higher than nighttime values (0.75 vs. 0.39, <em>p</em> = 0.02), whereas no diurnal difference was observed in normotensive pregnancies.</div></div><div><h3>Conclusions</h3><div>Upcr demonstrates significant diurnal variation in hypertensive pregnancies. These findings support reevaluating current proteinuria thresholds and incorporating time-of-day considerations in Upcr interpretation.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114893"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145767364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The sonographic subpubic area is a predictor of anal incontinence after a first vaginal delivery: A prospective cohort study 一项前瞻性队列研究:首次阴道分娩后,超声检查阴下区域是肛门失禁的预测指标。
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2025-12-04 DOI: 10.1016/j.ejogrb.2025.114867
Bram Packet , Rik Van Severen , Laura Cattani , Adela Samesova , Florian Ramakers , Helena Williams , Jute Richter , Jan Deprest
{"title":"The sonographic subpubic area is a predictor of anal incontinence after a first vaginal delivery: A prospective cohort study","authors":"Bram Packet ,&nbsp;Rik Van Severen ,&nbsp;Laura Cattani ,&nbsp;Adela Samesova ,&nbsp;Florian Ramakers ,&nbsp;Helena Williams ,&nbsp;Jute Richter ,&nbsp;Jan Deprest","doi":"10.1016/j.ejogrb.2025.114867","DOIUrl":"10.1016/j.ejogrb.2025.114867","url":null,"abstract":"<div><h3>Objectives</h3><div>To study the association between the subpubic arch angle and area, the latter a novel estimator of maternal pelvic outlet dimensions, and postpartum anal incontinence.</div></div><div><h3>Methods</h3><div>Convenience sample from a prospective observational cohort study conducted in primiparous women who delivered vaginally at term. A transperineal ultrasound (TPUS) volume was acquired before the second stage for <em>offline</em> measurement of the subpubic arch angle, area, and levator ani hiatal area. Six to eight weeks postpartum, anal incontinence was self-reported using the St. Marks Incontinence Score (SMIS), and perineal and pelvic floor muscle structural changes were assessed by TPUS. Intra and inter-observer agreement on subpubic arch angle and area measurements was assessed. Anal incontinence and its potential predictors were studied in multivariable logistic regression. Last, a prediction model for postpartum anal incontinence was fitted based on antenatal predictors (age, BMI, anal incontinence at term). Individual sonographic variables were added to this baseline model to assess whether they influenced discriminatory accuracy by comparing the AUC.</div></div><div><h3>Results</h3><div>Data on 156 participants were available, of whom 73.7 % delivered spontaneously. Postpartum anal respective fecal incontinence was reported by 70.5 % and 7.7 %. The incidence of obstetric anal sphincter injury was 3.8 %. Inter- and intra-rater agreement was better for the subpubic area (ICC 0.95, 95 % CI 0.92–0.97 and ICC 0.97, 95 % CI 0.95–0.98) than the subpubic arch angle. Anal incontinence at term (aOR 3.77, 95 % CI1.46–9.73) and assisted vaginal birth (aOR 4.05, 95 %CI 1.27–12.92) were the strongest predictors of <em>postpartum</em> anal incontinence. Although less strong, the subpubic area was also an independent predictor (aOR 1.44, 95 %1.08–1.93). Addition of the subpubic area to the antenatal model did not improve discriminatory accuracy (AUC baseline model: 0.70, 95 % CI 0.61–0.80).</div></div><div><h3>Conclusion</h3><div>The subpubic area can be reliably measured on TPUS. Herein, it was an independent predictor of postpartum anal incontinence. Nonetheless, the addition of this variable to a model containing <em>antenatal</em> predictors only, did not improve discriminatory accuracy for <em>postpartum</em> anal incontinence, questioning its added value for individualized risk prediction.</div></div><div><h3>Funding</h3><div>Research Council Flanders (grant number 1S49923N).</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114867"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145780057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of ovarian stimulation in adolescents and young adults undergoing fertility preservation 保持生育能力的青少年和年轻成人卵巢刺激的特点。
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2025-12-10 DOI: 10.1016/j.ejogrb.2025.114886
Tiffany Brun , Marie Sineux , Vincent Lavoué , Ludivine Dion , Jean Levêque , Solène Duros
{"title":"Characteristics of ovarian stimulation in adolescents and young adults undergoing fertility preservation","authors":"Tiffany Brun ,&nbsp;Marie Sineux ,&nbsp;Vincent Lavoué ,&nbsp;Ludivine Dion ,&nbsp;Jean Levêque ,&nbsp;Solène Duros","doi":"10.1016/j.ejogrb.2025.114886","DOIUrl":"10.1016/j.ejogrb.2025.114886","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the ovarian response to controlled ovarian hyperstimulation (COH) performed for fertility preservation (FP) in adolescents and young adults (AYA) aged ≤20 years with that of adult women aged 25–35 years.</div></div><div><h3>Materials and Methods</h3><div>This retrospective cohort study included 66 COH cycles in AYA patients (≤20 years) and 107 cycles in adults (25–35 years) treated between January 2014 and March 2022 for oocyte vitrification. Outcomes assessed included the number of mature oocytes vitrified, total oocytes retrieved, total rFSH dose, peak estradiol levels, maturation rate, and duration of stimulation.</div></div><div><h3>Results</h3><div>Groups were comparable regarding BMI, smoking status, AMH, stimulation protocol, and gonadotropin type. Median number of mature oocytes was not statistically different between groups: (9.5 (AYA) vs. 9.0 (A), p = 80.19). The maturation index was significantly lower in AYA (0.80 vs. 0.88, p = 80.02). Peak estradiol was lower in AYA (1267 pg/mL vs. 1582 pg/mL, p = 80.04). Other stimulation parameters were similar.</div></div><div><h3>Conclusion</h3><div>Fertility preservation through COH in adolescents and young adults appears as effective as in adult women in terms of mature oocyte yield. Nevertheless, AYA patients exhibit a lower oocyte maturation rate and lower peak estradiol levels. Larger studies are needed to confirm these findings and better characterise age-related physiological differences in ovarian response.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114886"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145780660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pregnancy outcomes after laparotomic or laparoscopic myomectomy: A multicenter retrospective cohort study 剖腹或腹腔镜子宫肌瘤切除术后妊娠结局:一项多中心回顾性队列研究。
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2026-01-14 DOI: 10.1016/j.ejogrb.2026.114964
Bernies J. Bos , Elisabeth R. Knorren Loes , Cathy van de Graaf , Marjan van den Berg , Jeroen R. Dijkstra , Mirjam J.A. Apperloo , Jorien M. Woolderink
{"title":"Pregnancy outcomes after laparotomic or laparoscopic myomectomy: A multicenter retrospective cohort study","authors":"Bernies J. Bos ,&nbsp;Elisabeth R. Knorren Loes ,&nbsp;Cathy van de Graaf ,&nbsp;Marjan van den Berg ,&nbsp;Jeroen R. Dijkstra ,&nbsp;Mirjam J.A. Apperloo ,&nbsp;Jorien M. Woolderink","doi":"10.1016/j.ejogrb.2026.114964","DOIUrl":"10.1016/j.ejogrb.2026.114964","url":null,"abstract":"<div><h3>Objective</h3><div>Expend knowledge about pregnancy rate, live birth rate and outcomes after laparotomic or laparoscopic myomectomy.</div></div><div><h3>Methods</h3><div>In four hospitals in the Netherlands patients with a FIGO type 3–7 myoma who underwent laparoscopic or laparotomic myomectomy between January 2007 and April 2022, were retrospectively identified. Indication for the myomectomy was abnormal uterine bleeding, bulk-related symptoms and/or infertility. Baseline characteristics, data of the myomectomy and outcomes including pregnancy rates, live birth rates and complications during pregnancy or delivery, were extracted from electronic patient records. Logistic regression analysis was used to identify factors influencing the live birth rate.</div></div><div><h3>Results</h3><div>One hundred sixty four patients were included. Sixty one patients had 94 pregnancies after the myomectomy (pregnancy rate: 37 %), resulting in 64 deliveries in 50 patients (30 %). The most common mode of delivery was caesarean section (CS) (n = 40, 62 %). Forty-six patients had a live birth after the myomectomy (live birth rate: 28 %), together they had 60 children. No major complications related to the myomectomy occurred during pregnancy or delivery. Patients who had been pregnant before the myomectomy and patients with infertility as primary symptom, had a higher probability of live birth after myomectomy.</div></div><div><h3>Conclusion</h3><div>Patients who underwent a laparotomic or laparoscopic myomectomy have a live birth rate of 28%, with a pregnancy rate of 37%. The most common mode of delivery is CS. No major complications were found during delivery. Patients with a pregnancy prior to the myomectomy or with infertility as primary symptom had an increased probability of live birth after myomectomy.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114964"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146003177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurocognitive function, psychosocial characteristics, and occupational performance across menstrual phases in young adults with and without primary dysmenorrhea 有或无原发性痛经的青壮年经期的神经认知功能、社会心理特征和职业表现
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2026-01-14 DOI: 10.1016/j.ejogrb.2026.114965
Aysenur Karakus , Semanur Inanc , Gokcen Akyurek
{"title":"Neurocognitive function, psychosocial characteristics, and occupational performance across menstrual phases in young adults with and without primary dysmenorrhea","authors":"Aysenur Karakus ,&nbsp;Semanur Inanc ,&nbsp;Gokcen Akyurek","doi":"10.1016/j.ejogrb.2026.114965","DOIUrl":"10.1016/j.ejogrb.2026.114965","url":null,"abstract":"<div><h3>Objective</h3><div>To examine phase-related variations in cognitive, emotional, and occupational functioning among women with and without primary dysmenorrhea (PD).</div></div><div><h3>Study design</h3><div>A repeated-measures case-control study was conducted at a university-based research laboratory and hospital outpatient unit.</div></div><div><h3>Participants</h3><div>Seventy-nine women with PD and fifty-nine asymptomatic women aged 17-25 years participated.</div></div><div><h3>Main outcome measures</h3><div>Menstrual pain intensity (Visual Analog Scale), menstrual attitudes (Menstrual Attitudes Questionnaire), body awareness (Body Awareness Questionnaire), occupational performance and satisfaction (Canadian Occupational Performance Measure), and self-esteem (Rosenberg Self-Esteem Scale) were assessed across three menstrual phases. Cognitive functions (attention, processing speed, and executive control) were evaluated using the Stroop Test and the Paced Auditory Serial Addition Test. Mann-Whitney U and Friedman tests were used for between- and within-group analyses, and regression models identified predictors of occupational performance and self-esteem.</div></div><div><h3>Results</h3><div>Women with PD reported higher pain intensity (p&lt;0.001), lower BMI (p=0.022), and a more frequent family history of dysmenorrhea (p = 0.016). They also had more negative and proactive menstrual attitudes (p=0.01-0.04), lower occupational performance and satisfaction (p&lt;0.001), and reduced self-esteem (p&lt;0.001). Cognitive performance significantly declined during the luteal phase (p=0.01-0.004). No significant differences were observed in body awareness (p&gt;0.05).</div></div><div><h3>Conclusion</h3><div>Women with PD experience cognitive, emotional, and occupational challenges that extend beyond menstrual pain. Integrative, multidisciplinary interventions addressing both physical and psychosocial domains are recommended to improve overall functioning and well-being.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114965"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145973290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of placenta accreta spectrum on sexual and psychological health: a comparative analysis using FSFI and SF-36 胎盘增生谱对性健康和心理健康的影响:FSFI和SF-36的比较分析
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2026-01-06 DOI: 10.1016/j.ejogrb.2026.114942
Dini Hidayat , Sri Dewi Rahmawati Syarief , Vyanda Sri Weningtyas , Faradiba Janiyustika
{"title":"Impact of placenta accreta spectrum on sexual and psychological health: a comparative analysis using FSFI and SF-36","authors":"Dini Hidayat ,&nbsp;Sri Dewi Rahmawati Syarief ,&nbsp;Vyanda Sri Weningtyas ,&nbsp;Faradiba Janiyustika","doi":"10.1016/j.ejogrb.2026.114942","DOIUrl":"10.1016/j.ejogrb.2026.114942","url":null,"abstract":"<div><h3>Background</h3><div>Placenta accreta spectrum (PAS) is a potentially life-threatening obstetric condition characterized by abnormal placental adherence to the myometrium. While hysterectomy remains the standard definitive management, conservative strategies such as wedge resection or delayed hysterectomy have been increasingly adopted to preserve fertility. The comparative impact of these approaches on women’s quality of life (QoL), particularly social and sexual functioning, has not been well investigated.</div></div><div><h3>Method</h3><div>A cross-sectional study included 185 women who underwent caesarean section (CS) for histopathologically confirmed PAS at Dr. Hasan Sadikin General Hospital, Bandung, West Java, from 2022 to 2024. A total of 161 met the inclusion criteria and were analyzed, while 24 were excluded. Sexual function and QoL were assessed using the Female Sexual Function Index (FSFI) and the 36-Item Short Form Health Survey (SF-36), respectively. Non-parametric analysis using the Mann–Whitney <em>U</em> test was applied for scale scores and categorical comparisons were analyzed using Chi-square or Fisher’s exact test, with p &lt; 0.05 considered significant.</div></div><div><h3>Result</h3><div>Median FSFI scores for desire (3.0 [2.5–3.5] vs. 3.0 [2.0–4.0], p = 0.015), arousal (2.5 [2.0–3.5] vs. 3.0 [2.0–4.0], p = 0.048), and pain (2.4 [2.0–2.7] vs. 3.0 [2.0–4.0], p = 0.021) differed significantly between the hysterectomy and conservative groups, although median values for desire were similar. Other FSFI domains and total scores were not significantly different (p &gt; 0.05). In the SF-36, a statistically significant difference was observed only in the social functioning domain, despite comparable median scores between groups.</div></div><div><h3>Conclusion</h3><div>Conservative management in PAS was associated with better preservation of specific aspects of sexual function, particularly pain and arousal.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114942"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145973308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application and validation of AI-driven methods to explore patient experiences of pre-cervical cancer 人工智能驱动方法在宫颈癌前期患者体验探索中的应用与验证
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2026-01-10 DOI: 10.1016/j.ejogrb.2026.114953
Michael Y. Luo , Christopher Y.K. Williams
{"title":"Application and validation of AI-driven methods to explore patient experiences of pre-cervical cancer","authors":"Michael Y. Luo ,&nbsp;Christopher Y.K. Williams","doi":"10.1016/j.ejogrb.2026.114953","DOIUrl":"10.1016/j.ejogrb.2026.114953","url":null,"abstract":"<div><h3>Objective</h3><div>We sought to apply novel natural language processing (NLP) tools to explore patient experiences of pre-cervical cancer on social media and validate the performance of these tools.</div></div><div><h3>Methods</h3><div>All posts and comments were extracted from the forum r/PreCervicalCancer on social media platform <em>Reddit</em>. Using BERTopic, posts were clustered into topics according to their semantic similarity, which were manually reviewed. Topic headings were derived using a large language model (LLM) and compared to manually curated headings. Clustering outliers were reassigned by BERTopic, an LLM and by manual methods in parallel and compared. Post and comment sentiment were quantitatively analysed using VADER. Post upvote scores and comments counts were analysed to measure community engagement.</div></div><div><h3>Results</h3><div>4592 posts were extracted from r/PreCervicalCancer. Posts clustered into 10 different topics using BERTopic with 88.0% accuracy. 80.0% of topic headings generated by GPT-4o mini were deemed appropriate. Reassignment of clustering outliers by BERTopic and GPT-4o mini was limited, 52.8% and 41.1% accuracy, respectively. Key clinical findings reflect several common concerns among patients, particularly regarding specific lasting physical and psychological impact of procedures like LEEP, result anxiety, and challenges in healthcare navigation. Comments had less negative sentiment than posts (Cohen’s d = 0.46), suggesting support.</div></div><div><h3>Conclusions</h3><div>In this cross-sectional study, we validated NLP tools to analyse content, sentiment and reactions to 4592 posts on pre-cervical cancer. Our findings suggest that, with minimal human oversight, automated methods can accurately conduct large-scale analyses of similar clinical content, unlocking new insights of patient experiences using non-traditional data sources.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114953"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145973386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergency contraception pills among female students: Use, knowledge, perceptions, and expectations 女大学生紧急避孕药的使用、知识、认知和期望
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2026-01-10 DOI: 10.1016/j.ejogrb.2026.114946
Alison Catilaz , Anne-Laure Clairet , Marilia Girault , Stéphanie Paris , Virginie Nerich
{"title":"Emergency contraception pills among female students: Use, knowledge, perceptions, and expectations","authors":"Alison Catilaz ,&nbsp;Anne-Laure Clairet ,&nbsp;Marilia Girault ,&nbsp;Stéphanie Paris ,&nbsp;Virginie Nerich","doi":"10.1016/j.ejogrb.2026.114946","DOIUrl":"10.1016/j.ejogrb.2026.114946","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess the rate of emergency contraception pills (ECP) use among female students, and to examine their characteristics, knowledge, perceptions and expectations regarding ECPs, with particular attention to the experiences and feedback of those who had previously used it.</div></div><div><h3>Study design</h3><div>A cross-sectional, voluntary online survey was conducted among female women students at the Marie and Louis Pasteur University during the 2022–2023 academic year. The questionnaire mainly assessed demographics, contraceptive use, knowledge and perceptions of ECP, and experiences with ECP use. Descriptive and comparative analyses were performed.</div></div><div><h3>Results</h3><div>Among 2,157 female students who completed the survey, i.e., response rate of 15.1 %, 39.1 % reported having previously used ECP at least once, with use increasing significantly with age groups (&lt; 20, 20–29, &gt;29 years). Female students who had used ECP showed higher knowledge and more positive perceptions about ECP, were more likely to use condoms, and primarily consulted pharmacists and the Internet for information. Most ECPs were obtained from community pharmacies, with nearly three-quarters of pharmacists providing information, but only 4 % of dispensations occurred in a confidential space. The main reasons for ECP use were condom breakage, forgetting regular contraception, or not using any regular contraceptive method. Practical and theoretical knowledge about ECP was higher among users.</div></div><div><h3>Conclusion</h3><div>Most female students were aware of emergency contraception and its indications, with a moderate rate of use. These results highlight the need to improve access to reliable information and to explore the role of healthcare professionals and educational strategies in promoting appropriate ECP use.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114946"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145973397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An overview of the transgender population’s knowledge of the role of physical therapy during the transitioning process: a cross-sectional survey study 跨性别人群在过渡过程中物理治疗作用的知识概述:一项横断面调查研究。
IF 1.9 4区 医学
European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2026-02-20 Epub Date: 2025-12-22 DOI: 10.1016/j.ejogrb.2025.114905
Sara Cortés-Amador , Amanda Vidal-Chaparro , David Hernández-Guillén , Fernando Domínguez-Navarro , Laura Fuentes-Aparicio
{"title":"An overview of the transgender population’s knowledge of the role of physical therapy during the transitioning process: a cross-sectional survey study","authors":"Sara Cortés-Amador ,&nbsp;Amanda Vidal-Chaparro ,&nbsp;David Hernández-Guillén ,&nbsp;Fernando Domínguez-Navarro ,&nbsp;Laura Fuentes-Aparicio","doi":"10.1016/j.ejogrb.2025.114905","DOIUrl":"10.1016/j.ejogrb.2025.114905","url":null,"abstract":"<div><h3>Purpose</h3><div>Gender reassignment surgery is the surgical option for many transgender populations. However, there is little information about the gender reassignment process, especially the role that pelvic floor physiotherapy has in this process. The purpose of this study was to analyze the knowledge that the participants had about the gender reassignment process, about the experience of those who had gone through it, and about the knowledge they had about the role of pelvic floor physiotherapy in this process.</div></div><div><h3>Methods</h3><div>This was a cross-sectional study. A self-developed online survey b was developed consisting of 3 sociodemographic questions and 23 questions on participants’ knowledge and perception of pelvic floor physical therapy and the reassignment surgery process.</div></div><div><h3>Results</h3><div>Of the 35 participants aged 19–52 in the study, 22 identified as female, and 13 as male. Only 37.1 % were aware of the post-surgery role of pelvic floor physiotherapists. Additionally, 25.7 % considered consulting a physiotherapist, and 22.8 % had contemplated doing so. Just 11.4 % of those who had surgery sought pelvic floor physiotherapy. Common post-surgery issues included urethral stenosis, vaginal elasticity problems, and difficulty reaching orgasm, aligning with previous research. Notably, individuals receiving physiotherapy reported greater improvement in post-surgery sequelae.</div></div><div><h3>Conclusion</h3><div>Gender reassignment is a complex process that affects all aspects of the person and requires greater humanization of health professionals. Physiotherapy has shown significant barriers in terms of accessibility and knowledge of the benefits that physiotherapy can bring to this population. It is important to include in the curricula of different health professions the implications of a sex reassignment process to offer adequate support to the needs of the population.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"318 ","pages":"Article 114905"},"PeriodicalIF":1.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145827000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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