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European Journal of Dermatology最新文献

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Extramammary Paget's disease in situ of the scrotum and penis with cervical lymph node metastasis of unknown origin. 阴囊和阴茎的乳腺外原位佩吉特病伴来源不明的颈部淋巴结转移。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4917
Daiki Karube, Koji Kamiya, Soichiro Kado, Atsuko Sato, Mamitaro Ohtsuki, Mayumi Komine
{"title":"Extramammary Paget's disease in situ of the scrotum and penis with cervical lymph node metastasis of unknown origin.","authors":"Daiki Karube, Koji Kamiya, Soichiro Kado, Atsuko Sato, Mamitaro Ohtsuki, Mayumi Komine","doi":"10.1684/ejd.2025.4917","DOIUrl":"https://doi.org/10.1684/ejd.2025.4917","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"325-326"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sQUIZ your knowledge! Erythematous-violaceous plaques on the thigh progressing to ecchymosis. 测试你的知识！大腿红斑-紫斑发展为瘀斑。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4936
Pedro José Ezomo Gervilla, Francisco Javier De La Torre Gomar, Ricardo Ruiz-Villaverde
{"title":"sQUIZ your knowledge! Erythematous-violaceous plaques on the thigh progressing to ecchymosis.","authors":"Pedro José Ezomo Gervilla, Francisco Javier De La Torre Gomar, Ricardo Ruiz-Villaverde","doi":"10.1684/ejd.2025.4936","DOIUrl":"https://doi.org/10.1684/ejd.2025.4936","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"347-349"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sQuiz your knowledge! Yellowish nodules on the knees and elbows: a warning sign of a potentially fatal disease. 测试你的知识！膝盖和肘部的黄色结节：潜在致命疾病的警告信号。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4938
Cherif Malek, Hammami Fatma, Turki Hamida
{"title":"sQuiz your knowledge! Yellowish nodules on the knees and elbows: a warning sign of a potentially fatal disease.","authors":"Cherif Malek, Hammami Fatma, Turki Hamida","doi":"10.1684/ejd.2025.4938","DOIUrl":"https://doi.org/10.1684/ejd.2025.4938","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"351-353"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sQUIZ your knowledge! Linear pinkish-orange papules on the forearms. 测试你的知识！前臂上呈粉红色和橙色的线状丘疹。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4939
María Zulaika-Lloret, Francisco Javier De La Torre-Gomar, Ricardo Ruiz-Villaverde
{"title":"sQUIZ your knowledge! Linear pinkish-orange papules on the forearms.","authors":"María Zulaika-Lloret, Francisco Javier De La Torre-Gomar, Ricardo Ruiz-Villaverde","doi":"10.1684/ejd.2025.4939","DOIUrl":"https://doi.org/10.1684/ejd.2025.4939","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"353-354"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Journal club: Dupilumab and remibrutinib as treatment for chronic spontaneous urticaria: new pathways in disease control. 杂志俱乐部：Dupilumab和remibrutinib治疗慢性自发性荨麻疹：疾病控制的新途径。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4935
César Silva Ferreira, Belén Rodríguez Sánchez, Luis Jiménez-Briones, Simon Goller, Paloma Garcia Piqueras
{"title":"Journal club: Dupilumab and remibrutinib as treatment for chronic spontaneous urticaria: new pathways in disease control.","authors":"César Silva Ferreira, Belén Rodríguez Sánchez, Luis Jiménez-Briones, Simon Goller, Paloma Garcia Piqueras","doi":"10.1684/ejd.2025.4935","DOIUrl":"https://doi.org/10.1684/ejd.2025.4935","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"339-342"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Six cases of ectopic cutaneous ossification associated with GNAS gene variants. 与GNAS基因变异相关的异位性皮肤骨化6例。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4919
Cheng Zhang, Wei He, Qiaoyu Cao, Hongsong Ge, Jie Yao, Jing Chu, Xinjie Lin, Ming Li, Wei Song
{"title":"Six cases of ectopic cutaneous ossification associated with GNAS gene variants.","authors":"Cheng Zhang, Wei He, Qiaoyu Cao, Hongsong Ge, Jie Yao, Jing Chu, Xinjie Lin, Ming Li, Wei Song","doi":"10.1684/ejd.2025.4919","DOIUrl":"10.1684/ejd.2025.4919","url":null,"abstract":"<p><p>The GNAS gene gives rise to stimulatory G protein Gs-alpha (Gsα), a pivotal transducer of hormonal signalling pathways. Variants inherited maternally lead to reduced Gsα activity in certain tissues, resulting in resistance to multiple hormones and manifesting clinically as pseudohypoparathyroidism (PHP). In contrast, paternal transmission is linked to pseudopseudohypoparathyroidism (PPHP), which is characterized by extensive ectopic cutaneous ossification but lacks endocrine resistance. Thus, the phenotypic spectrum arising from GNAS gene variants is profoundly influenced by the parent-of-origin effect. Objectives: To analyse the clinical characteristics and GNAS gene variants of six patients with ectopic cutaneous ossification. We retrospectively analysed six patients with GNAS-related ectopic cutaneous ossification, with evaluation of clinical features, laboratory results, histopathology, and genetic testing data. Six patients presented with cutaneous ossification and Albright hereditary osteodystrophy (AHO) phenotype associated with GNAS gene variants. The identified variants comprised a splicing mutation (c.718+1G>A), two nonsense mutations (c.91C>T and c.103C>T), and three frameshift mutations (c.518_521del, c.565_568del, and c.522_523del). Notably, the frameshift variant c.522_523del has not been previously reported in the literature. Five patients were diagnosed with PHP, one with PPHP. This study expands the mutational spectrum of GNAS by identifying a novel variant and highlights the phenotypic heterogeneity of GNAS-associated disorders. Early molecular diagnosis, integrated with clinical evaluation, is essential for timely intervention, mitigating disease progression, and enhancing the overall quality of life in affected children.</p>","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"307-312"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secukinumab-induced erythema multiforme-like drug eruption in generalized pustular psoriasis: a case report and literature review. 广泛性脓疱性银屑病致多形红斑样药疹1例报告并文献复习。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4922
Jing Sun, Zhaoyang Wang, Zigang Xu
{"title":"Secukinumab-induced erythema multiforme-like drug eruption in generalized pustular psoriasis: a case report and literature review.","authors":"Jing Sun, Zhaoyang Wang, Zigang Xu","doi":"10.1684/ejd.2025.4922","DOIUrl":"10.1684/ejd.2025.4922","url":null,"abstract":"<p><p>Secukinumab is an IL-17A inhibitor that selectively binds to IL-17A and inhibits its interaction with IL-17 receptors, thereby reducing the production of pro-inflammatory cytokines, chemokines, and tissue-damaging mediators. Secukinumab has been proven to rapidly improve erythema and pustules in adult and paediatric generalized pustular psoriasis (GPP) patients. Here, we report a case study of erythema multiforme-like drug eruption induced by secukinumab and provide an overview of all cases reported so far. A systematic literature search of publications was conducted from inception to September 2024 via PubMed and Web of Science Core Collection, in order to identify all cases of drug hypersensitivity reactions associated with secukinumab. We conducted a search for retrospective and prospective studies, case series, case reports, and data from Phase II and III clinical trials related to immune-related (or potentially immune-related) adverse events associated with the use of secukinumab. In total, four cases of drug hypersensitivity reactions associated with secukinumab were identified. Drug hypersensitivity reactions associated with secukinumab are relatively rare. The recognition of potential rare adverse events by clinicians is important and may expand our understanding of immune-mediated diseases.</p>","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"279-284"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of rhododendrol-induced leukoderma successfully treated with topical delgocitinib and UVA1 phototherapy. 局部delgocitinib联合UVA1光疗治疗杜鹃花诱导的白皮病1例。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4930
Marina Teraoka, Toshiaki Kogame, Gyohei Egawa, Naotomo Kambe, Rie Arai, Kenji Kabashima
{"title":"A case of rhododendrol-induced leukoderma successfully treated with topical delgocitinib and UVA1 phototherapy.","authors":"Marina Teraoka, Toshiaki Kogame, Gyohei Egawa, Naotomo Kambe, Rie Arai, Kenji Kabashima","doi":"10.1684/ejd.2025.4930","DOIUrl":"https://doi.org/10.1684/ejd.2025.4930","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"331-333"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of pemphigoid gestationis successfully treated with systemic corticosteroids combined with dupilumab. 一例类天疱疮妊娠成功治疗与全身皮质类固醇联合杜匹单抗。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4912
Chen Sun, Yue-Ping Zeng
{"title":"A case of pemphigoid gestationis successfully treated with systemic corticosteroids combined with dupilumab.","authors":"Chen Sun, Yue-Ping Zeng","doi":"10.1684/ejd.2025.4912","DOIUrl":"https://doi.org/10.1684/ejd.2025.4912","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"320-321"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mogamulizumab-associated rash and lymphocytopenia coinciding with treatment response of Sézary syndrome. mogamulizumab相关的皮疹和淋巴细胞减少症与ssamzary综合征的治疗反应一致。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2025-08-01 DOI: 10.1684/ejd.2025.4942
Simon Goller, Matthias Goebeler, Marion Wobser
{"title":"Mogamulizumab-associated rash and lymphocytopenia coinciding with treatment response of Sézary syndrome.","authors":"Simon Goller, Matthias Goebeler, Marion Wobser","doi":"10.1684/ejd.2025.4942","DOIUrl":"https://doi.org/10.1684/ejd.2025.4942","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 4","pages":"342-343"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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