2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)最新文献_第6页

Design and implementation of data acquisition system based on FPGA and USB interface in fourier-transform mass spectrometer 基于FPGA和USB接口的傅里叶变换质谱仪数据采集系统的设计与实现

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401494

Dayu Li, Yajing Fang, Wei Huang, Xianrui Huang

引用次数: 1

A fast iterative reconstruction method based on the selective total variation for sparse angular CT 基于选择性全变分的稀疏角CT快速迭代重建方法

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401471

Huijun Li, Shuxu Zhang, Kehong Yuan, Linjing Wang, Yingying Peng

{"title":"A fast iterative reconstruction method based on the selective total variation for sparse angular CT","authors":"Huijun Li, Shuxu Zhang, Kehong Yuan, Linjing Wang, Yingying Peng","doi":"10.1109/BMEI.2015.7401471","DOIUrl":"https://doi.org/10.1109/BMEI.2015.7401471","url":null,"abstract":"Sparse angular Computer Tomography (CT) is a rapidly developing imaging modality that reconstructs high-quality images from sparse data toward low-dose x-rays. The effectiveness of conventional total variation (TV) algorithm is limited by the over-smoothness on the edges and slow convergence. To mitigate this drawback, we proposed an improved fast iterative reconstruction method based on the minimization of selective image TV. The presented selective TV model is derived by linking the regularity metric to the local gradient of images, and selectively applies different degrees of regularization (the value of p) to background and potential signal locations for the purpose of preserving the edge details. In order to further speed up the convergence, we draws on a fast variant of The Iterative-Shrinkage-Thresholding Algorithm (ISTA), which uses a special linear combination of the two previous iterate results as the initial value of next iteration for more accurate correction. Experiments on simulated Shepp-Logan phantom are performed. The results demonstrated that the new method not only protected the edge of the image characteristics, but also significantly improved the convergence speed of the iterative reconstruction.","PeriodicalId":119361,"journal":{"name":"2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129805441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison imaging effect of acoustic radiation force excitation in ultrasound 超声声辐射力激励成像效果比较

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401599

Dequan Guo, Hao Yin, Richen Liu

引用次数: 0

Automatic mesh fusion for dental crowns and roots in a computer-aided orthodontics system 计算机辅助正畸系统中牙冠与牙根的自动网状融合

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401516

Xiaomeng Wei, Li Chen, Chaowei Gao

{"title":"Automatic mesh fusion for dental crowns and roots in a computer-aided orthodontics system","authors":"Xiaomeng Wei, Li Chen, Chaowei Gao","doi":"10.1109/BMEI.2015.7401516","DOIUrl":"https://doi.org/10.1109/BMEI.2015.7401516","url":null,"abstract":"In computer-aided orthodontics systems, an essential task is to present tooth models. Model data may come from different sources. A laser scanner can generate a relatively fine mesh of the dental crown, while a CBCT (cone beam computerized tomography) scanner can generate a mesh complete but coarser. To combine both advantages, it is natural to consider fusing the fine crown with the coarser but complete root. Since data sources are different, the sizes and vertex densities of the two kinds of meshes don't match well. This paper presents an automatic method to address these problems and fuse the fine crowns with the coarse roots. First, the root part of the CBCT generated mesh is extracted according to the laser scanned crown mesh. Then, the two parts are connected via a Bezier surface. The mesh of the transitional part is constructed by triangulating sampling points over the Bezier surface, and subsequently faired using the mean curvature flow method. The proposed method can generate meshes with a fine crown and a complete root, which will facilitate the subsequent orthodontics planning process.","PeriodicalId":119361,"journal":{"name":"2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132791795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

ECG signal compressed sensing using the wavelet tree model 基于小波树模型的心电信号压缩感知

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401499

Zhicheng Li, Yang Deng, Hong Huang, S. Misra

{"title":"ECG signal compressed sensing using the wavelet tree model","authors":"Zhicheng Li, Yang Deng, Hong Huang, S. Misra","doi":"10.1109/BMEI.2015.7401499","DOIUrl":"https://doi.org/10.1109/BMEI.2015.7401499","url":null,"abstract":"Compressed Sensing (CS) is a novel approach of compressing, which can reconstruct a sparse signal much below Nyquist rate of sampling. Though ECG signals can be well approximated by some wavelet basis, the noise still influences the ECG wavelet decomposition and also reduces the effectiveness of the signal reconstruction. In this note, we present a compressed sensing method to reconstruct ECG signals in MITBIH [1] arrhythmia based on different wavelet families. Our approach is composed of two steps. The first step is to use Condensing Sort and Select Algorithm (CSSA) to dampen the impact of the noise for ECG signals and get sparse signals to estimate and replace raw ECG signals, and then, the second step is to use CS method to compress and transfer those filtered signals. The result is evaluated by some indices like Percentage Root Mean Square Difference (PRD), Mean Square Error (MSE), Peak Signal To Noise Ratio (PSNR), and Correlation Coefficient (CoC). These reconstructed results are comprehensively compared by 4:1 compression ratio. These results indicate that Symlets and Daubechies wavelet families have better performance for all parameters compared to other wavelet families and most of existing results.","PeriodicalId":119361,"journal":{"name":"2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114223872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Prediction model of human body composition based on physiological information entropy 基于生理信息熵的人体成分预测模型

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401555

Bo Chen, Xiu-e Gao, A. Zhang

引用次数: 4

Mathematical modeling and simulations of the pathophysiology of Type-2 Diabetes Mellitus 2型糖尿病病理生理的数学建模与模拟

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401518

F. Nani, Mingxian Jin

{"title":"Mathematical modeling and simulations of the pathophysiology of Type-2 Diabetes Mellitus","authors":"F. Nani, Mingxian Jin","doi":"10.1109/BMEI.2015.7401518","DOIUrl":"https://doi.org/10.1109/BMEI.2015.7401518","url":null,"abstract":"The pathophysiology of Type 2 Diabetes Mellitus (T2DM) is modelled using a coupled system of non-linear deterministic differential equations. An attempt is made to construct to a clinically plausible mathematical model that incorporates the homeostasis associated with endocrinological regulation of glucose and glycogen levels in the human body, by the hormones, insulin and glucagon. The model variables include the concentrations of glucose in the venous blood plasma, the concentration of glycogen in the liver/tissues, the concentration of the hormone glucagon, and the concentration of insulin in the venous blood plasma. The physiological interactions between the model parameters are depicted by clinically measurable rate constants and biophysically quantifiable stoichiometric coefficients. The processes of gluconeogenesis, glycogenolysis, and pulsatile insulin secretion during type 2 diabetes are modelled using plausible auxiliary functions. Investigative computer simulations are performed to elucidate various hypothetical scenarios of glycemia, patho-physiology of T2DM and insulinoma associated hypoglycemia which results from excessive insulin production probably due to a tumor. This study has demonstrated the necessity of simultaneous monitoring of plasma glucose, glucagon, insulin, and glycogen levels in the proper assessment of the pathophysiology of type 2 diabetes and during determination of the therapeutic efficacy of anti-diabetic drugs.","PeriodicalId":119361,"journal":{"name":"2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116517328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

A tightly secure multi-party-signature protocol in the plain model 在普通模型中一个高度安全的多方签名协议

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401588

L. Wei, Jieqing Ai, Shenghan Liu

引用次数: 4

Simulation of the formation mechanism of coronary thrombosis based on DEM-CFD coupling 基于DEM-CFD耦合的冠状动脉血栓形成机理模拟

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401467

X. Hou, Yuetian Shi, Jianting Yao, Xin Sun, Kailiang Zhang

引用次数: 5

Virtual screening of cytochrome P450 2A6 inhibitors from traditional Chinese medicine using support vector machine and molecular docking 基于支持向量机和分子对接的中药细胞色素P450 2A6抑制剂虚拟筛选

2015 8th International Conference on Biomedical Engineering and Informatics (BMEI) Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401557

Ganggang Luo, Fang Lu, Ludi Jiang, Yilian Cai, Yanling Zhang

{"title":"Virtual screening of cytochrome P450 2A6 inhibitors from traditional Chinese medicine using support vector machine and molecular docking","authors":"Ganggang Luo, Fang Lu, Ludi Jiang, Yilian Cai, Yanling Zhang","doi":"10.1109/BMEI.2015.7401557","DOIUrl":"https://doi.org/10.1109/BMEI.2015.7401557","url":null,"abstract":"Cytochrome P450 2A6 (CYP2A6), which is a member of the cytochrome P450 (CYP450) mixed-function oxidase system and is highly expressed in liver, is involved in the metabolism of drugs in the body. The inhibition of it often reduces the metabolic rate of the corresponding metabolites and then may cause unwanted drug-drug interaction (DDI). In this study, discriminative models of CYP2A6 inhibitors were created by using the support vector machine (SVM) method. And the optimal model was selected based on three assessment criteria, including accuracy, sensitivity and specificity, which were all above 95%. Then, the optimal model was used to distinguish potential inhibitors of CYP2A6 from traditional Chinese medicine database (TCMD), which resulting in a hit list of 619 compounds. These compounds were further refined by using molecular docking and then 23 compounds with higher scores than the original ligand in the crystal structure of CYP2A6 enzyme were retained. Among them, Peucedanin, which has better prediction results, might exhibits inhibition effect on CYP2A6. This paper suggests the applicability of computational methods for obtaining potential inhibitors of CYP2A6 from Natural Products, and also provides guidance for the rational application of drugs in clinical.","PeriodicalId":119361,"journal":{"name":"2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133734470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1