European journal of paediatric dentistry最新文献

筛选
英文 中文
Fracture Resistance of Space Maintainers Produced Using 3D Printable Materials. 使用三维打印材料制作的空间维持器的抗断裂性。
IF 2.2 2区 医学
European journal of paediatric dentistry Pub Date : 2024-09-01 DOI: 10.23804/ejpd.2024.2104
N Aktaş, D Atabek
{"title":"Fracture Resistance of Space Maintainers Produced Using 3D Printable Materials.","authors":"N Aktaş, D Atabek","doi":"10.23804/ejpd.2024.2104","DOIUrl":"https://doi.org/10.23804/ejpd.2024.2104","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to evaluate the fracture resistance of space maintainers (SMs) produced using 3D-printable materials (metal, resin and polyetheretherketone [PEEK]) after thermal aging and compare them with conventional space maintainers.</p><p><strong>Methods: </strong>A standardised typodont model for paediatric dentistry was utilised, and band and loop space maintainers were designed digitally using computer-aided design (CAD) technology. Four groups were established: Conventional, 3D printed metal, 3D printed resin, and 3D printed PEEK. Fracture resistance was assessed after 10,000 thermal cycles, simulating oral conditions. Fracture tests were conducted using a universal testing machine, applying vertical force to the band and loop junction until fracture. Statistical analyses were performed using one-way ANOVA and the Tukey HSD test (P<0.05).</p><p><strong>Conclusion: </strong>Although the fracture resistance values showed that metal, resin, and PEEK 3D printed band and loop space maintainers can be acceptable clinically, the permanent resin may be preferable to printable material because of their aesthetic properties.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental defects of enamel in childhood cancer survivors: A systematic review and meta-analysis. 儿童癌症幸存者的釉质发育缺陷:系统回顾和荟萃分析。
IF 2.2 2区 医学
European journal of paediatric dentistry Pub Date : 2024-07-01 DOI: 10.23804/ejpd.2024.2256
A Allam, N Camoni, S Cirio, C Salerno, G Campus, M G Cagetti
{"title":"Developmental defects of enamel in childhood cancer survivors: A systematic review and meta-analysis.","authors":"A Allam, N Camoni, S Cirio, C Salerno, G Campus, M G Cagetti","doi":"10.23804/ejpd.2024.2256","DOIUrl":"https://doi.org/10.23804/ejpd.2024.2256","url":null,"abstract":"<p><strong>Aim: </strong>The present systematic review and meta-analysis (Prospero registration number: CRD42023472016) aims to assess the prevalence of developmental defects of enamel (DDEs), qualitatively and/or quantitatively, in childhood cancer survivors (CCS) and evaluate, when possible, these data in comparison with those found in healthy children.</p><p><strong>Methods: </strong>Three electronic databases (PubMed, Embase, Scopus) were searched from January 2003 to January 2024 for studies reporting on DDEs in children with a mean age not exceeding 16 years at the time of the study who underwent antineoplastic therapy. The ROBINS-I and the Joanna Briggs Institute (JBI) tools were used to assess the risk of bias. Included studies with comparable outcomes underwent random effects models meta-analysis using Stata®18.</p><p><strong>Conclusion: </strong>CCS showed a higher prevalence of DDEs, both qualitative and quantitative, compared to healthy children. The meta- analysis showed higher odds of developing qualitative defects over quantitative defects in CCS. Conclusions regarding the association between the type of therapy administered, age of therapy initiation, and prevalence of DDEs could not be drawn due to insufficient data. A lack of a standardized method of detecting enamel defects posed a challenge in the qualitative and quantitative analysis.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of treatment outcomes with passive presurgical infant orthopaedics in patients with non-syndromic cleft lip and or palate: A systematic review conducted according to PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. 评估非综合征唇腭裂患者手术前婴儿被动矫形的治疗效果:根据 PRISMA 指南和 Cochrane 《干预措施系统综述手册》进行的系统综述。
IF 2.2 2区 医学
European journal of paediatric dentistry Pub Date : 2024-07-01 DOI: 10.23804/ejpd.2024.2056
N Bhatia, A K Subramanian, N Ramasamy, M Di Blasio, V Ronsivalle, M Cicciù, G Minervini
{"title":"Evaluation of treatment outcomes with passive presurgical infant orthopaedics in patients with non-syndromic cleft lip and or palate: A systematic review conducted according to PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions.","authors":"N Bhatia, A K Subramanian, N Ramasamy, M Di Blasio, V Ronsivalle, M Cicciù, G Minervini","doi":"10.23804/ejpd.2024.2056","DOIUrl":"https://doi.org/10.23804/ejpd.2024.2056","url":null,"abstract":"<p><strong>Aim: </strong>The primary goal of the present comprehensive systematic review is to assess the treatment results attained through PSIO in individuals with NSCLP, as well as to explore its effectiveness. This will be accomplished by examining a range of existing published studies that focus on patient groups who have undergone PPIO.</p><p><strong>Materials: </strong>A comprehensive search strategy was devised by a single author for each database without language restrictions. The databases searched were PubMed, Cochrane library Google Scholar, Web of Science and Scopus. The search period was limited to the years 2001 to 2023. Duration and study design filter was used. Furthermore, conference proceedings, abstracts, and reference lists of relevant studies were sought to obtain additional records.</p><p><strong>Conclusion: </strong>The examined protocols for passive presurgical infant orthopaedics (PPIO) in individuals with CLP typically did not reveal notable treatment outcomes when compared to a lack of treatment across a range of domains. These domains encompass feeding patterns, facial aesthetics, maxillary dentoalveolar factors, cephalometric measurements, speech and language-related aspects, dental arch alignments, economic assessments, as well as occurrences of adverse effects or complications associated with applied appliances or procedures.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upper Jaw Development After Lingual Laser Frenectomy and Myofuntional Therapy. 舌侧激光切除术和肌肉治疗后的上颌骨发育
IF 2.2 2区 医学
European journal of paediatric dentistry Pub Date : 2024-07-01 DOI: 10.23804/ejpd.2024.2143
L De Simone, D Martinelli, M Tieri, A Monaco, D Tripodi
{"title":"Upper Jaw Development After Lingual Laser Frenectomy and Myofuntional Therapy.","authors":"L De Simone, D Martinelli, M Tieri, A Monaco, D Tripodi","doi":"10.23804/ejpd.2024.2143","DOIUrl":"https://doi.org/10.23804/ejpd.2024.2143","url":null,"abstract":"<p><strong>Aim: </strong>Over the years, the role of the lingual frenulum in the development of skeletal structures has been evaluated. However, the effect of short lingual frenulum treatment on bone structures is unclear. We need to investigate the effect of surgery and myofunctional therapy on maxillary development. This could be the rationale to establish an orthodontic interception protocol.</p><p><strong>Methods: </strong>The case-control study was carried out in the Operative Unit of Pedodontics of the University Dental Clinic, at the Department of Medical, Oral and Biotechnological Sciences of the University of \"G. D'Annunzio\" Chieti-Pescara. The study population consisted in thirty children. The data were collected through anamnesis carried out by qualified health personnel before dental examination. Photos, frenulum length and cast measurements were taken. Student's t-test statistical analysis was used. Significance was ascertained based on the obtained P value of less than 0.01.</p><p><strong>Conclusion: </strong>The results confirmed the benefit of laser surgical treatment. The change in parameters related to the anterior palate region showed the power of frenectomy and myofunctional therapy in restoring the tongue's ability to stimulate bone development. The protocol adopted in the following study could be used in interceptive orthodontics. However, further studies are needed to evaluate the effects on the upper jaw over the long term that have higher sample numbers.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interdisciplinary management of orofacial lesions in early childhood: paediatric alert system at University of Verona. 幼儿口面部损伤的跨学科管理:维罗纳大学的儿科警报系统。
IF 3.6 2区 医学
European journal of paediatric dentistry Pub Date : 2024-06-03 Epub Date: 2024-05-01 DOI: 10.23804/ejpd.2024.2141
N Zerman, A Zangani, C Maffeis, A Pietrobelli, G Piacentini, F Zotti, R De Manzoni, R Silva, A Cordiano, E Spinas, P F Nocini
{"title":"Interdisciplinary management of orofacial lesions in early childhood: paediatric alert system at University of Verona.","authors":"N Zerman, A Zangani, C Maffeis, A Pietrobelli, G Piacentini, F Zotti, R De Manzoni, R Silva, A Cordiano, E Spinas, P F Nocini","doi":"10.23804/ejpd.2024.2141","DOIUrl":"10.23804/ejpd.2024.2141","url":null,"abstract":"<p><strong>Background: </strong>Orofacial trauma (OFT) occurs frequently in children and requires thorough evaluation not only by paediatric dentists but also by all specialists involved in emergency services, particularly in cases involving children under 3 years of age, given their inability to directly participate in clinical-anamnestic evaluations. Addressing early childhood orofacial trauma resulting from maltreatment, this study explores the key role played by various healthcare professionals, including paediatric dentists, general dentists, maxillofacial surgeons, dental hygienists, and paediatricians, in the optimal management of these cases. In the event of trauma due to suspected or confirmed mistreatment, it is essential that all healthcare workers involved have precise knowledge of the appropriate course of action from both a clinical and legal point of view, guaranteeing maximum protection for the young patient. This is particularly significant as cases of mistreatment with apparently minor consequences can degenerate into situations of irreparable severity. The latest guidelines from the International Association of Dental Traumatology (IADT) in 2020 continue to emphasise the potential correlation between OFT and cases of abuse or violence. Recent recommendations in the literature highlight the importance of facilitating mandatory reporting of incidents to relevant authorities and improving information sharing between dental healthcare professionals and child welfare services. A new flow diagram, called Paediatric Orofacial Trauma Alert (P.O.T.A.), has been proposed at the University of Verona. This tool is specifically designed to assist specialists dealing with early childhood orofacial trauma cases by assisting them in identifying potential cases of maltreatment. In this innovative approach, the collaborative efforts of general dentists, paediatric dentists, maxillofacial surgeons, dental hygienists and paediatricians play a vital role in cases of abuse. In addition to restoring the oral health of young patients, these professionals can activate a vast network of contacts, ensuring not only optimal oral health care but also providing comprehensive support to victims. The objective is to safeguard not only the physical but also the psychological well-being of these vulnerable subjects.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dog-Assisted Therapy (DAT) for the management of anxiety during paediatric dental care. A scoping review. 狗辅助治疗(DAT)用于缓解儿科牙科护理过程中的焦虑。范围综述。
IF 3.6 2区 医学
European journal of paediatric dentistry Pub Date : 2024-06-03 Epub Date: 2024-03-01 DOI: 10.23804/ejpd.2024.2001
A Garrocho-Rangel, M Rosales-Bérber, D Ríos-Méndez, J Flores-Velázquez, D Trejo-Herbert, F Pozos-Guillén, A Pozos-Guillén
{"title":"Dog-Assisted Therapy (DAT) for the management of anxiety during paediatric dental care. A scoping review.","authors":"A Garrocho-Rangel, M Rosales-Bérber, D Ríos-Méndez, J Flores-Velázquez, D Trejo-Herbert, F Pozos-Guillén, A Pozos-Guillén","doi":"10.23804/ejpd.2024.2001","DOIUrl":"10.23804/ejpd.2024.2001","url":null,"abstract":"<p><strong>Aim: </strong>Distraction techniques in paediatric dentistry can be effective in decreasing the child's attention span from an unpleasant or stressful procedure. Distraction is achieved through imagination, audio, and/or visual stimuli. It has been shown that the accompaniment and participation of animals or pets, specifically dogs (Dog-Assisted Therapy or DAT), during medical, oral, and therapeutic activities can improve the physical and mental health of patients, especially children. However, there is limited information available regarding the impact of incorporating a certified therapy dog into the paediatric dental environment as a distraction strategy to alleviate anxiety levels during dental procedures.</p><p><strong>Methods: </strong>This scoping review aimed to identify and review published articles concerning the use of DAT in paediatric dentistry. The article discusses indications, benefits, and potential risks to human health and safety in clinical settings. Eligible sources encompass clinical trials, observational studies, and narrative reviews written in either English or Spanish and published over the last two decades, sourced from four electronic databases. Ultimately, seven pertinent studies were included in the review.</p><p><strong>Conclusion: </strong>DAT presents itself as a promising alternative in managing anxiety and stress among children during dental visits. The integration of a therapy dog and its handler into the paediatric oral care team should be thoughtfully considered by clinicians as a means to enhance the comfort and compliance of apprehensive patients.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140157857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Different effects of whitening treatment on natural teeth and teeth treated with Icon resin: an experimental study in vitro. 美白处理对天然牙齿和用 Icon 树脂处理过的牙齿的不同影响:体外实验研究。
IF 3.6 2区 医学
European journal of paediatric dentistry Pub Date : 2024-06-03 Epub Date: 2024-03-01 DOI: 10.23804/ejpd.2024.2014
R Favero, M Pellarin, D Bresolato, A Di Fiore, A Zuccon, A Volpato, L Favero
{"title":"Different effects of whitening treatment on natural teeth and teeth treated with Icon resin: an experimental study in vitro.","authors":"R Favero, M Pellarin, D Bresolato, A Di Fiore, A Zuccon, A Volpato, L Favero","doi":"10.23804/ejpd.2024.2014","DOIUrl":"10.23804/ejpd.2024.2014","url":null,"abstract":"<p><strong>Background: </strong>It is quite common for white spots to develop on a tooth, due sometimes to a defective formation of the enamel layer, and sometimes to patches of demineralisation as a result of poor oral hygiene during orthodontic treatment with fixed braces. ICON DMG is currently the only noninvasive treatment for white spots. After a preliminary etching, it infiltrates the enamel, filling the spaces between the prisms with a resinous material that has a refraction coefficient very similar to that of healthy tooth enamel. The aim of this study was to test the efficacy of professional whitening procedures on teeth previously treated with ICON. The study hypothesis was that infiltration with ICON resin creates a barrier capable of preventing the bleaching action of the whitening agent.</p><p><strong>Materials: </strong>White spots were artificially created on one half of the vestibular surface of 12 human teeth, while the other half was protected with a composite adhesive. The white spots were infiltrated with ICON and the protective adhesive was subsequently removed. A professional teeth whitening procedure was then completed on both halves of the teeth. A statistical analysis was performed to compare spectrophotometric recordings obtained before and after the ICON infiltration and teeth whitening procedures.</p><p><strong>Conclusion: </strong>The whitening procedure modified the colour of the teeth on the half not infiltrated with ICON (p<0.05), but there was no statistically significant change in colour on the half infiltrated with ICON. The presence of the ICON resin seems to act as a partial barrier to the action of the whitening agent.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Humanisation and health needs in children: present or future? 人性化与儿童的健康需求:现在还是未来?
IF 3.6 2区 医学
European journal of paediatric dentistry Pub Date : 2024-06-03 Epub Date: 2024-02-01 DOI: 10.23804/ejpd.2024.2012
A V Brescia, A Mastroianni, G Parisi, G Di Gennaro, R Docimo, L Montesani
{"title":"Humanisation and health needs in children: present or future?","authors":"A V Brescia, A Mastroianni, G Parisi, G Di Gennaro, R Docimo, L Montesani","doi":"10.23804/ejpd.2024.2012","DOIUrl":"10.23804/ejpd.2024.2012","url":null,"abstract":"<p><strong>Aim: </strong>For a few years, teledentistry has been an emerging innovative strategy with potential in the field of paediatric dentistry. There are still few studies in this regard, so further research is needed to verify and ensure that teledentistry is not only an accessible mode of communication, but above all effective and evidence-based. This study aimed to use a preliminary telematic approach to promote the compliance of patients in the developmental age during the first dental visit.</p><p><strong>Materials: </strong>Two hundred patients were selected according to the eligibility criteria, and distributed in two groups: a study group with the preliminary telematic approach (ATP) before the first visit and a control group with traditional first visit without ATP. Through an ordinal semi-proportional regression model, the degrees of collaboration between the study and control groups were compared, correcting the estimate for age groups, the presence of systemic pathologies, disorders of cognition, attention and learning, degree of anxiety and previous medical-dental experiences.</p><p><strong>Conclusion: </strong>The preliminary telematic approach could be useful as a support to the traditional paediatric dental visit, to promote better management and fidelity of the patient, reducing anxiety and increasing collaboration during the first visit.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139982695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of two different remineralising toothpastes in children with drug-controlled asthma and allergic rhinitis: a randomised clinical trial. 评估药物控制哮喘和过敏性鼻炎患儿使用的两种不同再矿化牙膏:随机临床试验。
IF 3.6 2区 医学
European journal of paediatric dentistry Pub Date : 2024-06-03 Epub Date: 2024-02-01 DOI: 10.23804/ejpd.2024.2130
A Scribante, M Pascadopoli, P Bergomi, A Licari, G L Marseglia, F M Bizzi, A Butera
{"title":"Evaluation of two different remineralising toothpastes in children with drug-controlled asthma and allergic rhinitis: a randomised clinical trial.","authors":"A Scribante, M Pascadopoli, P Bergomi, A Licari, G L Marseglia, F M Bizzi, A Butera","doi":"10.23804/ejpd.2024.2130","DOIUrl":"10.23804/ejpd.2024.2130","url":null,"abstract":"<p><strong>Aim: </strong>To compare the efficacy of two remineralising toothpastes in children suffering from asthma and allergic rhinitis after a 6-month study.</p><p><strong>Methods: </strong>40 patients aged between 6-14 years with enamel demineralisations were enrolled for the study at the Unit of Dental Hygiene of the University of Pavia (Italy). The following indices were collected: Schiff air index (SAI), plaque index (PI), bleeding on probing (BoP), salivary pH, Basic Erosive Wear Examination (BEWE), susceptibility index (SI) for hard and soft tissues' pathologies, and decayed missing filled teeth (DMFT). After mechanical debridement with piezoelectric instrumentation and glycine powder, patients were equally divided into two groups: Group 1 using a toothpaste with zinc hydroxyapatite, and Group 2 using a toothpaste containing calcium sodium phosphosilicate. The toothpaste had to be used twice a day. The time frames of the study were: baseline (T0), after 1 month (T1), after 3 months (T2), after 6 months (T3).</p><p><strong>Conclusion: </strong>The tested toothpastes can be proposed for home use in children with asthma and allergic rhinitis as they significantly reduced dental sensitivity and periodontal indices.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139734825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silver diamine fluoride: A stem cell cytotoxicity and dentin growth factor release in-vitro study. 二胺氟化银:一项干细胞细胞毒性和牙本质生长因子释放的体外研究。
IF 3.6 2区 医学
European journal of paediatric dentistry Pub Date : 2024-06-03 Epub Date: 2023-06-01 DOI: 10.23804/ejpd.2023.1928
M M Khalil, A Bashir, Y Monjazebi, M Shah, A R Tawfik, I Hussein, M Jamal
{"title":"Silver diamine fluoride: A stem cell cytotoxicity and dentin growth factor release in-vitro study.","authors":"M M Khalil, A Bashir, Y Monjazebi, M Shah, A R Tawfik, I Hussein, M Jamal","doi":"10.23804/ejpd.2023.1928","DOIUrl":"10.23804/ejpd.2023.1928","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effect of 38% SDF and its serial dilutions on the Stem cells from Human Exfoliated Deciduous teeth (SHED) and its ability to release growth factors from deciduous dentine.</p><p><strong>Methods: </strong>The viability of SHED post-exposure to 38%, 3.8%, 0.38%, 0.038%, and 0.0038% SDF were assessed at 2, 5, and 7 days using the CyQuant assay, and results were validated using the MTT assay. The osteogenic differentiation of the cells was also investigated post-exposure to 0.0038% SDF. The release of the growth factors; TGF-β1, FGF-b, BMP-2, and VEGF from deciduous dentin discs exposed to 38% SDF, 0.0038% SDF, Ca(OH)2, MTA, and 17% EDTA were examined using ELISA. Statistical analysis was performed using means and standard deviations (p < 0.05). Two-way ANOVA compared the means of more than two groups with Tukey's multiple comparison test. The unpaired t-test was also used to compare the differences between the two data sets.</p><p><strong>Conclusion: </strong>38% SDF released dentinogenic growth factors from dentin discs, potentially explaining its role in reactionary dentinogenesis. Moreover, 0.0038% SDF resulted in a non-cytotoxic concentration that enhanced cellular proliferation and released bioactive molecules from dentin comparable to the 38% concentration. After further investigations, the 0.0038% dilution of SDF could present itself as a clinical concentration.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10257146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信