European Addiction Research最新文献

{"title":"Morbidity through 3 Years of Age in Children of Women Using Methamphetamine during Pregnancy: A National Registry Study.","authors":"Roman Gabrhelík,&nbsp;Svetlana Skurtveit,&nbsp;Blanka Nechanská,&nbsp;Viktor Mravčík,&nbsp;Marte Handal","doi":"10.1159/000527238","DOIUrl":"https://doi.org/10.1159/000527238","url":null,"abstract":"<p><strong>Background: </strong>There is a lack of studies on methamphetamine (MA) exposure and morbidity in children beyond the perinatal period.</p><p><strong>Objectives: </strong>We compared morbidity in children (0-3 years) with prenatal MA exposure to opioid-exposed and to non-exposed children.</p><p><strong>Methods: </strong>We used data from a Czech nationwide, registry-based cohort study (2000-2014). Children, who reached 3 years of age, of mothers hospitalized with (i) MA use disorder during pregnancy (MA; n = 194), (ii) opioid use disorder during pregnancy (opioids; n = 166), and (iii) general population (GP; n = 1,294,349) with no recorded history of substance use disorder (SUD). Information on inpatient contacts, length of stay, and diagnoses (International Statistical Classification of Diseases and Related Health Problems 10th Revision [ICD-10]) were assessed. Crude and adjusted odds ratios (aOR), 95% confidence interval (CI) for the risk of hospitalization, and for getting diagnosis from the ICD-10 diagnosis chapters were calculated using binary logistic regression. A stratified analysis on hospitalizations with SUD of mothers was performed.</p><p><strong>Results: </strong>No significant differences were found in the measures of hospitalization between the MA and opioid groups. Children prenatally exposed to MA and opioids had higher numbers of hospitalizations and diagnoses and longer stays in hospital than children in the GP. Increased risks of certain infectious and parasitic diseases were found in both MA (aOR = 1.6; CI: 1.1-2.3) and opioid (aOR = 1.9; 1.3-2.8) groups as compared to the GP group. The most pronounced difference in stratified analysis on maternal hospitalizations related to SUD after birth was observed for injury, poisoning, and certain other consequences of external causes in the strata of the MA group who had hospitalized mothers (aOR 6.3, 1.6-24.6) compared to the strata without maternal hospitalizations (aOR 1.4, 0.9-2.3).</p><p><strong>Conclusion: </strong>This study suggests that children born to mothers using MA during pregnancy have similar morbidity during the first 3 years of life but higher than the GP. The excess of risk was primarily due to infections and injuries in the MA group.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 1","pages":"19-29"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9290385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Risk Gaming Is Associated with Frequent Substance Use: An Exploratory Survey among Young Adults.","authors":"Francesco Di Carlo,&nbsp;Valeria Verrastro,&nbsp;Maria Chiara Alessi,&nbsp;Antonella Sociali,&nbsp;Arianna Ida Altomare,&nbsp;Chiara Di Natale,&nbsp;Gianfranco Stigliano,&nbsp;Andrea Miuli,&nbsp;Aliseo Lalli,&nbsp;Gilberto Di Petta,&nbsp;Stefania Chiappini,&nbsp;Mauro Pettorruso,&nbsp;Henrietta Bowden-Jones,&nbsp;Mark D Griffiths,&nbsp;Giovanni Martinotti","doi":"10.1159/000529544","DOIUrl":"https://doi.org/10.1159/000529544","url":null,"abstract":"<p><strong>Introduction: </strong>Internet gaming disorder (IGD) is an emerging condition within the field of behavioural addictions. IGD has been demonstrated to be highly comorbid with many other mental health disorders. Among these, substance use has been associated with IGD, and there are underlying similarities between behavioural addictions and substance use disorders. The main aims of the present study were (i) to investigate the association between high-risk gaming and substance use among young adults drawn from the general Italian population; and (ii) to explore the psychopathological correlates of high-risk gaming.</p><p><strong>Methods: </strong>Lifetime substance use, type of substances consumed, and frequency of use were investigated through an online survey in a sample of 913 adults aged 18-40 years. High-risk gaming was assessed using the ten-item Internet Gaming Disorder Test (IGDT-10). Psychopathology was assessed using the Revised 90-item Symptom Checklist (SCL-90-R).</p><p><strong>Results: </strong>High-risk gaming prevalence rate was 4.4%. High-risk gamers scored higher on all dimensions of psychopathology, confirming the association between high-risk gaming and psychiatric distress. Regarding substance use, high-risk gamers were more commonly polysubstance users and more commonly made use of psychodysleptic substances. High-risk gamers were more commonly frequent substance users, and 32.5% of high-risk gamers used or had used psychoactive substances often or everyday throughout their lives.</p><p><strong>Discussion and conclusion: </strong>The findings are in line with the concept of a common neurobiological vulnerability for both gaming and substance use. There is the need for more research to examine the phenomenology of gaming and its interplay with substance use to help develop effective interventions and prevention strategies.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 4","pages":"241-252"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10044767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards a New Definition of the Typical Day in the Alcohol Use Disorder Identification Test-Consumption.","authors":"Annelien Esselink,&nbsp;Rob H L M Bovens,&nbsp;Dike H M Van de Mheen,&nbsp;Maurice J W Gesthuizen,&nbsp;Jolanda J P Mathijssen","doi":"10.1159/000530823","DOIUrl":"10.1159/000530823","url":null,"abstract":"<p><strong>Introduction: </strong>The standard screening instrument for alcohol problems in the current primary care, the Alcohol Use Disorder Identification Test-Consumption (AUDIT-C), contains a question about alcohol consumption \"on a typical day.\" Since this is a term that leaves room for multiple interpretations and the differences between alcohol consumption on weekends and weekdays are not taken into account, this study examines whether the latter distinction improves the prediction validity of the screening instrument.</p><p><strong>Methods: </strong>A subgroup of 852 participants of the Dutch version of Dry January (\"NoThanks\") 2022 got the annual \"NoThanks\" survey, including questions about their alcohol consumption on weekends and weekdays, and the original ten AUDIT questions. The full AUDIT was used as golden standard. Sensitivity, specificity, and receiver operating characteristic curves were calculated for the original and different versions of the AUDIT-C.</p><p><strong>Results: </strong>Of all participants, 67 percent were hazardous drinkers (AUDIT ≥8) and 27 percent were harmful drinkers (AUDIT ≥16). For the original AUDIT-C, the cut-off score with the most balanced combination of sensitivity and specificity for hazardous drinking in men was 7 and in women was 6. For harmful drinking, this was 8 and 7, respectively. Certain versions performed equally well as the original. For harmful drinkers, the highest area under the receiver operating characteristic curve (AUROC) was 0.814 and 0.866 for the original AUDIT-C, for men and women, respectively. Only for hazardous drinking men, the AUDIT-C with weekend day (AUROC = 0.887) performed slightly better than the original.</p><p><strong>Conclusion: </strong>Distinguishing weekend- and weekday alcohol consumption in the AUDIT-C does not lead to better predictions of problematic alcohol use. However, the distinction between weekends and weekdays provides more detailed information for healthcare professionals and can be used without having to compromise too much on validity.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 4","pages":"264-271"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10044778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19-Related Death in Patients with Alcohol or Substance Use Disorders.","authors":"Raimondo Maria Pavarin,&nbsp;Dario Consonni,&nbsp;Fabio Lucchi,&nbsp;Paolo Pandolfi,&nbsp;Silvia Marani,&nbsp;Francesco Palmese,&nbsp;Marco Domenicali","doi":"10.1159/000527542","DOIUrl":"https://doi.org/10.1159/000527542","url":null,"abstract":"<p><strong>Background: </strong>People with substance or alcohol use disorders (SUDs/AUDs) are likely to be more vulnerable to COVID-19 infection than the general population, but the evidence of COVID-19-related mortality in these patients is unclear.</p><p><strong>Objectives: </strong>The aim of the study was to verify whether patients with AUD and SUD have a higher mortality rate for COVID-19-related mortality compared to the general population.</p><p><strong>Method: </strong>We performed a follow-up study to assess mortality in 2020 in a cohort of patients diagnosed for the first time with AUDs or SUDs at the Public Health Services in the metropolitan area of Bologna (Northern Italy) from 2009 to 2019.</p><p><strong>Results: </strong>SUDs/AUDs patients present an excess mortality with respect to the general population for all causes of death and for COVID-19-related mortality.</p><p><strong>Conclusions: </strong>Our data support the need for prevention strategies in SUDs/AUDs patients such as vaccinations.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 1","pages":"67-70"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892992/pdf/ear-0029-0067.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10656680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What Do Young Adults Expect from the Recreational Use of Ecstasy (3,4-Methylenedioxymethamphetamine/Molly)? A Latent Class Analysis of a Convenience Sample of Dutch Young Adults.","authors":"Martha Charlotta de Jonge,&nbsp;Andrea Johanna Bukman,&nbsp;Tom Ter Bogt,&nbsp;Simone Arianne Onrust,&nbsp;Marloes Kleinjan","doi":"10.1159/000530330","DOIUrl":"https://doi.org/10.1159/000530330","url":null,"abstract":"<p><strong>Introduction: </strong>This study offers insights into Dutch young people's expected social and personal consequences of ecstasy use. Substance use expectancies are assumed to be an essential component in explaining substance use behaviour and, therefore, the development of effective substance use prevention and treatment strategies.</p><p><strong>Method: </strong>Dutch young adults with an online interest in drug-related social media posts were targeted with an online survey about their use of alcohol and drugs. This resulted in a convenience sample (N = 4182, 73.4% female, Mage = 21.11), of which 35.5% had used ecstasy at least once in their life and 29.3% had used ecstasy last year. Latent class analyses were used to identify subgroups based on both positive and negative expectancies of ecstasy use. Cross-class differences were examined using multinomial logistic regression.</p><p><strong>Results: </strong>This study yielded four distinct classes: only negative expectancies (13.6%), high positive and negative expectancies (23.5%), low to moderate positive and negative expectancies (20.6%), and mostly positive expectancies (22.4%). These classes differed significantly in lifetime experience with ecstasy use, intention to use ecstasy, perception of harmfulness and availability, and social norms regarding the use of ecstasy.</p><p><strong>Conclusion: </strong>Findings show that ecstasy use expectancies can be used to create meaningful classes of users and non-users, and that these classes are different enough to warrant varied prevention approaches. Expectancies young people have regarding the use of ecstasy are associated with various ecstasy use-related variables and should be taken into consideration when developing and implementing preventive interventions.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 3","pages":"231-240"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10245266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seasonality and Delirium Tremens in Hospitalized Patients with Alcohol Dependence Syndrome.","authors":"Ildikó Katalin Pribék,&nbsp;Bettina Kata Kádár,&nbsp;Lea Péter,&nbsp;Júlia Daróczy,&nbsp;András Bajsz,&nbsp;Csenge Sára Kovács,&nbsp;Ildikó Demeter,&nbsp;Zoltán Janka,&nbsp;Róbert Urbán,&nbsp;Zsolt Demetrovics,&nbsp;Bence András Lázár,&nbsp;Ildikó Kovács,&nbsp;János Kálmán,&nbsp;Bálint Andó","doi":"10.1159/000527973","DOIUrl":"https://doi.org/10.1159/000527973","url":null,"abstract":"<p><strong>Introduction: </strong>Due to the high rate of mortality, recognizing the contributing factors of alcohol-related delirium tremens (DT), which is the most severe form of alcohol withdrawal state (AWS) is pivotal in clinical settings. Previous studies suggested relationship between seasonality and other types of delirium; however, to our knowledge, this is the first empirical study which examined the role of seasonality in DT in alcohol dependence syndrome (ADS).</p><p><strong>Methods: </strong>A retrospective study was undertaken between 2008 and 2015; medical records of 1,591 patients were included, which yielded 2,900 hospital appearances. Three groups were formed based on the ICD-10 diagnoses: ADS, AWS, and DT. The characteristics of the groups were analysed with one-way ANOVA and χ2 tests. Multinomial logistic regression was used to explore the potential predictors of DT, including seasonality.</p><p><strong>Results: </strong>The highest incidence of DT was in spring (36.8%; χ2 (3) = 27.666; p < 0.001), especially in March (13.9%; χ2 (11) = 33.168; p < 0.001). Spring, higher mean age, higher presence of comorbid somatic disorders, and lower occurrence of comorbid psychiatric disorders were significant predictive variables for DT with the control of socio-demographic and clinical variables.</p><p><strong>Conclusions: </strong>The present study revealed that spring, especially March is a critical period in temperate climate zone regarding DT. This can be interpreted as a late winter effect since the temperature is lower in this month compared to other spring months. Furthermore, higher age and the occurrence of comorbid somatic disorders can be considered as risk factors in case of DT. These results support the need of further clinical studies to better understand the impact of seasonality on DT.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 2","pages":"83-91"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9651225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of COVID-19 Pandemic Lockdowns on Alcohol Consumption and Tobacco Smoking Behaviour in South Africa: A National Survey.","authors":"Witness Mapanga, Ashleigh Craig, Asanda Mtintsilana, Siphiwe N Dlamini, Justin Du Toit, Lisa J Ware, Shane A Norris","doi":"10.1159/000528484","DOIUrl":"10.1159/000528484","url":null,"abstract":"<p><strong>Introduction: </strong>During the first phase of the coronavirus (COVID-19) pandemic lockdowns in South Africa (SA), both alcohol and tobacco were considered non-essential goods and their sales were initially prohibited and further restricted to certain days and timeframes. This study investigates self-reported changes in alcohol consumption and tobacco smoking behaviour in the general population during the COVID-19 pandemic lockdowns in SA.</p><p><strong>Methods: </strong>A cross-sectional national survey was conducted in October 2021 (before the Omicron wave 4 and while SA was in low-level lockdown) among 3,402 nationally representative respondents (weighted to 39,640,674) aged 18 years and older. Alcohol consumption and tobacco use were assessed from the beginning of the lockdown towards the end of March 2020 until October 2021 using the WHO-AUDIT and the US Centre for Disease Control (CDC) Global Adult Tobacco Survey questionnaires, respectively.</p><p><strong>Results: </strong>Among those that drank alcohol (33.2%), 31.4% were classified as having a drinking problem that could be hazardous or harmful and 18.9% had severe alcohol use disorder during the COVID-19 lockdowns. Twenty-two per cent (22.0%) of those that reported alcohol consumption reported that the COVID-19 pandemic lockdowns changed their alcohol consumption habits, with 38.1% reporting a decreased intake or quitting altogether. Among the one in five respondents (19.2%) who had ever smoked, most reported smoking at the time of the survey (82.6%) with many classified as light smokers (87.8%; ≤10 cigarettes/day). Almost a third (27.2%) of those smoking reported that the COVID-19 pandemic lockdowns had changed their use of tobacco products or vaping, with 60.0% reporting a reduction/quitting tobacco use. Given that sales were restricted this indicates that people could still get hold of tobacco products. Heavy smoking was associated with older age (p = 0.02), those classified as wealthy (p &lt; 0.001), those who started or increased tobacco smoking during the pandemic lockdowns (p = 0.01) and residential provinces (p = 0.04).</p><p><strong>Conclusion: </strong>Given restrictions on the sale of alcohol and tobacco in SA between 27 March and August 17, 2020, during the pandemic, respondents reported an overall decline in alcohol consumption and tobacco use which might suggest that the regulatory restrictive strategies on sales had some effect but may be inadequate, especially during times where individuals are likely to experience high-stress levels. These changes in alcohol consumption and tobacco use were different from what was reported in several European countries, possibly due to differences in the restrictions imposed in SA when compared to these European countries.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 2","pages":"127-140"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Affordability of Alcoholic Beverages in the European Union.","authors":"Carolin Kilian,&nbsp;Jakob Manthey,&nbsp;Maria Neufeld,&nbsp;Jürgen Rehm","doi":"10.1159/000527096","DOIUrl":"https://doi.org/10.1159/000527096","url":null,"abstract":"<p><strong>Background: </strong>From a public health perspective, alcohol taxation should be designed to reduce alcohol affordability and thus alcohol consumption and related harms.</p><p><strong>Objectives: </strong>In this brief report, we estimate alcohol affordability in European Union Member States and associated countries and investigate whether affordability is related to national alcohol excise duties.</p><p><strong>Method: </strong>Beverage-specific affordability for beer, wine, and spirits were estimated based on the number of standard drinks a household could purchase based on their median monthly disposable household income in 2020. To determine the pooled affordability of alcohol, the beverage-specific estimates were weighted by the share of the beverage-specific per capita consumption in total recorded consumption. Pearson and Spearman rank correlations were calculated to establish the association between alcohol affordability and alcohol excise duty rates. All data were retrieved from official sources.</p><p><strong>Results: </strong>On average, a European household can purchase 1,628 standard drinks of alcohol with its monthly income, with affordability being highest in Germany, Austria, France, and Luxembourg. The affordability of spirits, but not that of beer or wine, was inversely correlated with the beverage-specific excise duty rates.</p><p><strong>Conclusions: </strong>Alcohol is affordable in the Member States of the European Union and associated countries, and low levels of excise duties on beer and wine appear to be unrelated to their affordability. Alcohol taxes should be increased to effectively reduce the affordability of alcoholic beverages in order to lower the alcohol-related health burden in Europe.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 1","pages":"63-66"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10650741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurochemical Correlates of Cue Reactivity in Individuals with Excessive Smartphone Use.","authors":"Gudrun M Henemann,&nbsp;Mike M Schmitgen,&nbsp;Nadine D Wolf,&nbsp;Dusan Hirjak,&nbsp;Katharina M Kubera,&nbsp;Fabio Sambataro,&nbsp;Tagrid Lemenager,&nbsp;Julian Koenig,&nbsp;Robert Christian Wolf","doi":"10.1159/000527095","DOIUrl":"https://doi.org/10.1159/000527095","url":null,"abstract":"<p><strong>Background: </strong>Excessive smartphone use (ESU), that is, a pattern of smartphone use that shows specific features of addictive behavior, has increasingly attracted societal and scientific interest in the past years. On the neurobiological level, ESU has recently been related to structural and functional variation in reward and salience processing networks, as shown by, for example, aberrant patterns of neural activity elicited by specific smartphone cues.</p><p><strong>Objectives: </strong>Expanding on these findings, using cross-modal correlations of magnetic resonance imaging (MRI)-based measures with nuclear imaging-derived estimates, we aimed at identifying neurochemical pathways that are related to ESU.</p><p><strong>Methods: </strong>Cross-modal correlations between functional MRI data derived from a cue-reactivity task administered in persons with and without ESU and specific PET/SPECT receptor probability maps.</p><p><strong>Results: </strong>The endogenous mu-opioid receptor (MOR) system was found to be significantly (FDR-corrected) correlated with fMRI data, and z-transformed correlation coefficients showed an association (albeit nonsignificant after FDR-correction) between MOR and the Smartphone Addiction Inventory \"withdrawal\" dimension.</p><p><strong>Conclusions: </strong>We could identify the MOR system as a neurochemical pathway associated with ESU. The MOR system is closely linked to the reward system, which has been recognized as a key player in addictive disorders. Together with its potential link to withdrawal, the MOR system hints toward a biologically highly relevant marker, which should be taken into consideration in the ongoing scientific discussion on technology-related addictive behaviors.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 1","pages":"71-75"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10651251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Client Feedback in Youth Mental Health and Addiction Care: A Controlled Study Comparing Two Treatment Cohorts.","authors":"Patty van Benthem, Renske Spijkerman, Peter Blanken, Albert Boon, Robert Vermeiren, Vincent Hendriks","doi":"10.1159/000528355","DOIUrl":"10.1159/000528355","url":null,"abstract":"<p><strong>Introduction: </strong>We investigated the value of systematic client feedback in youth mental health and addiction care. In the present study, we examined whether a client feedback intervention would result in improved therapeutic alliance and treatment outcomes.</p><p><strong>Methods: </strong>Two hundred and four adolescents participated in the study using a - non-randomized - between-group A/B design. In the first study group, 127 patients were offered 4 months of treatment as usual (TAU), and in the second study group, 77 patients received the client feedback intervention as an add-on to TAU during 4 months.</p><p><strong>Results: </strong>Youths who received systematic client feedback in addition to TAU did not show better treatment outcomes or better alliance ratings after 4 months than youths receiving TAU only. Sensitivity analyses, in which we compared the more adherent patients of the second study group with patients receiving TAU, did not show significant beneficial effects of client feedback either. Also, the client feedback intervention did not result in lower rates of early treatment drop-out.</p><p><strong>Discussion/conclusion: </strong>Our results cautiously suggest that client feedback does not have incremental effects on alliance and the treatment outcome for youth in mental health and addiction treatment. Moreover, our study highlights the challenges of implementing client feedback in clinical practice and the need for additional research addressing these challenges.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"29 1","pages":"52-62"},"PeriodicalIF":2.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9290896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}