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86P Functional impact of miR-205-5p on cervical cancer cell behavior and chemotherapy response 86P miR-205-5p 对宫颈癌细胞行为和化疗反应的功能影响
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103827
R.L. Causin , A.J.A. de Freitas , A.V.H. Lengert , I.N.F. Gomes , M.N. Rosa , R.D. Reis , R.M. Reis , M.M.C. Marques
{"title":"86P Functional impact of miR-205-5p on cervical cancer cell behavior and chemotherapy response","authors":"R.L. Causin , A.J.A. de Freitas , A.V.H. Lengert , I.N.F. Gomes , M.N. Rosa , R.D. Reis , R.M. Reis , M.M.C. Marques","doi":"10.1016/j.esmoop.2024.103827","DOIUrl":"10.1016/j.esmoop.2024.103827","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103827"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
88P Impact of poly(ADP-ribose) polymerase (PARP) mutations on interaction with PARP inhibitors (iPARPs) 88P 多（ADP-核糖）聚合酶（PARP）突变对与 PARP 抑制剂（iPARPs）相互作用的影响
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103829
J.F. Diaz Acosta , L.D. Gutierrez , G. Ardila Patiño , J. Carvajal Veloza , A.T. Palacios , C.A. Maya
{"title":"88P Impact of poly(ADP-ribose) polymerase (PARP) mutations on interaction with PARP inhibitors (iPARPs)","authors":"J.F. Diaz Acosta , L.D. Gutierrez , G. Ardila Patiño , J. Carvajal Veloza , A.T. Palacios , C.A. Maya","doi":"10.1016/j.esmoop.2024.103829","DOIUrl":"10.1016/j.esmoop.2024.103829","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103829"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
67P Multi-institutional evaluation of interrater agreement of biomarker-drug pair rankings based on the ESMO scale for clinical actionability of molecular targets (ESCAT) and sources of discordance 67P 基于ESMO分子靶点临床可操作性量表（ESCAT）的生物标记物-药物配对排序的多机构间一致性评价以及不一致的来源
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103811
A. Lebedeva , A. Taraskina , E. Belova , A. Kavun , M. Bartoletti , I. Bieche , G. Curigliano , C. Dupain , M. Kamal , E. Ignatova , C. Luchini , S. Poyarkov , A. Rios-Hoyo , C. Le Tourneau , E. Veselovsky , V. Mileyko , M. Ivanov
{"title":"67P Multi-institutional evaluation of interrater agreement of biomarker-drug pair rankings based on the ESMO scale for clinical actionability of molecular targets (ESCAT) and sources of discordance","authors":"A. Lebedeva , A. Taraskina , E. Belova , A. Kavun , M. Bartoletti , I. Bieche , G. Curigliano , C. Dupain , M. Kamal , E. Ignatova , C. Luchini , S. Poyarkov , A. Rios-Hoyo , C. Le Tourneau , E. Veselovsky , V. Mileyko , M. Ivanov","doi":"10.1016/j.esmoop.2024.103811","DOIUrl":"10.1016/j.esmoop.2024.103811","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103811"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
28P Clinical significance of TROP2 expression in lung adenocarcinomas 28P TROP2 在肺腺癌中表达的临床意义
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103774
K. Takamochi , T. Hayashi , H. Teukina , H. Tomita , K. Suzuki
{"title":"28P Clinical significance of TROP2 expression in lung adenocarcinomas","authors":"K. Takamochi , T. Hayashi , H. Teukina , H. Tomita , K. Suzuki","doi":"10.1016/j.esmoop.2024.103774","DOIUrl":"10.1016/j.esmoop.2024.103774","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103774"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142530479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
52P RAS mutation status and mutation type as potential predictive biomarkers for thrombosis in metastatic colorectal cancer: A tertiary center 12-year cohort analysis 52P RAS突变状态和突变类型作为转移性结直肠癌血栓形成的潜在预测生物标志物：三级中心12年队列分析
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103797
J. Leão Mendes, R.Q. Ferreira, R. Escaleira, F. Verdasca, M. Seladas, J. Gramaça, S. Duarte Oliveira
{"title":"52P RAS mutation status and mutation type as potential predictive biomarkers for thrombosis in metastatic colorectal cancer: A tertiary center 12-year cohort analysis","authors":"J. Leão Mendes, R.Q. Ferreira, R. Escaleira, F. Verdasca, M. Seladas, J. Gramaça, S. Duarte Oliveira","doi":"10.1016/j.esmoop.2024.103797","DOIUrl":"10.1016/j.esmoop.2024.103797","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103797"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142530939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
55P Impact of IHC/PCR discordance on immunotherapy (ICI) response in colorectal cancer (CRC) patients and prospects of liquid biopsy (LB) to replace conventional methods: Survival analysis of BLOOMSI trial 55P IHC/PCR不一致对结直肠癌（CRC）患者免疫疗法（ICI）反应的影响以及液体活检（LB）取代传统方法的前景：BLOOMSI试验的生存分析
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103800
A. Lebedeva , O.A. Kuznetsova , T. Grigoreva , A. Taraskina , D.A. Kravchuk , E. Belova , A. Kavun , E. Ignatova , E. Veselovsky , L. Belyaeva , V. Nikulin , A. Sergeeva , S. Aliyarova , V. Mileyko , A. Tryakin , M. Fedyanin , M. Ivanov
{"title":"55P Impact of IHC/PCR discordance on immunotherapy (ICI) response in colorectal cancer (CRC) patients and prospects of liquid biopsy (LB) to replace conventional methods: Survival analysis of BLOOMSI trial","authors":"A. Lebedeva , O.A. Kuznetsova , T. Grigoreva , A. Taraskina , D.A. Kravchuk , E. Belova , A. Kavun , E. Ignatova , E. Veselovsky , L. Belyaeva , V. Nikulin , A. Sergeeva , S. Aliyarova , V. Mileyko , A. Tryakin , M. Fedyanin , M. Ivanov","doi":"10.1016/j.esmoop.2024.103800","DOIUrl":"10.1016/j.esmoop.2024.103800","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103800"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
57P Response of gastric adenocarcinoma to neoadjuvant chemotherapy with respect to the presence or absence of HER2 overexpression: A prospective observational study 57P 胃腺癌对新辅助化疗的反应与是否存在 HER2 过度表达有关：前瞻性观察研究
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103802
P.K. Deb
{"title":"57P Response of gastric adenocarcinoma to neoadjuvant chemotherapy with respect to the presence or absence of HER2 overexpression: A prospective observational study","authors":"P.K. Deb","doi":"10.1016/j.esmoop.2024.103802","DOIUrl":"10.1016/j.esmoop.2024.103802","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103802"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
79P Targeting galectin-9 in BRCA mutant breast cancer 79P 以 BRCA 突变乳腺癌中的 galectin-9 为靶点
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103820
C.Y.T. So, Y. Li, K.T. Chow
{"title":"79P Targeting galectin-9 in BRCA mutant breast cancer","authors":"C.Y.T. So, Y. Li, K.T. Chow","doi":"10.1016/j.esmoop.2024.103820","DOIUrl":"10.1016/j.esmoop.2024.103820","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103820"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
81P Evaluating the effect of lenvatinib-resistance in hepatocellular carcinoma cells and in lenvatinib-resistant patient-derived PBMCs 81P 评估肝癌细胞和来伐替尼耐药患者来源的PBMC中来伐替尼耐药的影响
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103822
L. Amato , C. de Rosa , A. Ariano , S. Capaldo , C. Tuccillo , F. Ciardiello , E. Martinelli , G. Martini
{"title":"81P Evaluating the effect of lenvatinib-resistance in hepatocellular carcinoma cells and in lenvatinib-resistant patient-derived PBMCs","authors":"L. Amato , C. de Rosa , A. Ariano , S. Capaldo , C. Tuccillo , F. Ciardiello , E. Martinelli , G. Martini","doi":"10.1016/j.esmoop.2024.103822","DOIUrl":"10.1016/j.esmoop.2024.103822","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103822"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
11P A prospective study to evaluate the prognostic implications and molecular mechanism of SLC40A1 gene in primary acute myeloid leukemia 11P 一项评估原发性急性髓性白血病 SLC40A1 基因预后意义和分子机制的前瞻性研究
IF 7.1 2区 医学
ESMO Open Pub Date : 2024-10-01 DOI: 10.1016/j.esmoop.2024.103757
H. Goel , P. Tanwar
{"title":"11P A prospective study to evaluate the prognostic implications and molecular mechanism of SLC40A1 gene in primary acute myeloid leukemia","authors":"H. Goel , P. Tanwar","doi":"10.1016/j.esmoop.2024.103757","DOIUrl":"10.1016/j.esmoop.2024.103757","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"9 ","pages":"Article 103757"},"PeriodicalIF":7.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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